LOCUS       NM_007245               4456 bp    mRNA    linear   PRI 08-FEB-2025
DEFINITION  Homo sapiens ataxin 2 like (ATXN2L), transcript variant 1, mRNA.
ACCESSION   NM_007245 XM_001127543
VERSION     NM_007245.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4456)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 4456)
  AUTHORS   Lin,L., Li,X., Pan,C., Lin,W., Shao,R., Liu,Y., Zhang,J., Luo,Y.,
            Qian,K., Shi,M., Bin,J., Liao,Y. and Liao,W.
  TITLE     ATXN2L upregulated by epidermal growth factor promotes gastric
            cancer cell invasiveness and oxaliplatin resistance
  JOURNAL   Cell Death Dis 10 (3), 173 (2019)
   PUBMED   30787271
  REMARK    GeneRIF: ATXN2L promotes cell invasiveness and oxaliplatin
            resistance and can be upregulated by EGF via PI3K/Akt signaling.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4456)
  AUTHORS   Kaehler,C., Guenther,A., Uhlich,A. and Krobitsch,S.
  TITLE     PRMT1-mediated arginine methylation controls ATXN2L localization
  JOURNAL   Exp Cell Res 334 (1), 114-125 (2015)
   PUBMED   25748791
  REMARK    GeneRIF: ATXN2L associates with the protein
            arginine-N-methyltransferase 1 (PRMT1).
REFERENCE   4  (bases 1 to 4456)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4456)
  AUTHORS   Rietveld,C.A., Esko,T., Davies,G., Pers,T.H., Turley,P.,
            Benyamin,B., Chabris,C.F., Emilsson,V., Johnson,A.D., Lee,J.J., de
            Leeuw,C., Marioni,R.E., Medland,S.E., Miller,M.B., Rostapshova,O.,
            van der Lee,S.J., Vinkhuyzen,A.A., Amin,N., Conley,D.,
            Derringer,J., van Duijn,C.M., Fehrmann,R., Franke,L., Glaeser,E.L.,
            Hansell,N.K., Hayward,C., Iacono,W.G., Ibrahim-Verbaas,C.,
            Jaddoe,V., Karjalainen,J., Laibson,D., Lichtenstein,P.,
            Liewald,D.C., Magnusson,P.K., Martin,N.G., McGue,M., McMahon,G.,
            Pedersen,N.L., Pinker,S., Porteous,D.J., Posthuma,D.,
            Rivadeneira,F., Smith,B.H., Starr,J.M., Tiemeier,H., Timpson,N.J.,
            Trzaskowski,M., Uitterlinden,A.G., Verhulst,F.C., Ward,M.E.,
            Wright,M.J., Davey Smith,G., Deary,I.J., Johannesson,M., Plomin,R.,
            Visscher,P.M., Benjamin,D.J., Cesarini,D. and Koellinger,P.D.
  TITLE     Common genetic variants associated with cognitive performance
            identified using the proxy-phenotype method
  JOURNAL   Proc Natl Acad Sci U S A 111 (38), 13790-13794 (2014)
   PUBMED   25201988
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):E380. doi:
            10.1073/pnas.1424631112.. PMID: 25572966]
REFERENCE   6  (bases 1 to 4456)
  AUTHORS   Ong,S.E., Mittler,G. and Mann,M.
  TITLE     Identifying and quantifying in vivo methylation sites by heavy
            methyl SILAC
  JOURNAL   Nat Methods 1 (2), 119-126 (2004)
   PUBMED   15782174
REFERENCE   7  (bases 1 to 4456)
  AUTHORS   Beausoleil,S.A., Jedrychowski,M., Schwartz,D., Elias,J.E.,
            Villen,J., Li,J., Cohn,M.A., Cantley,L.C. and Gygi,S.P.
  TITLE     Large-scale characterization of HeLa cell nuclear phosphoproteins
  JOURNAL   Proc Natl Acad Sci U S A 101 (33), 12130-12135 (2004)
   PUBMED   15302935
REFERENCE   8  (bases 1 to 4456)
  AUTHORS   Brill,L.M., Salomon,A.R., Ficarro,S.B., Mukherji,M.,
            Stettler-Gill,M. and Peters,E.C.
  TITLE     Robust phosphoproteomic profiling of tyrosine phosphorylation sites
            from human T cells using immobilized metal affinity chromatography
            and tandem mass spectrometry
  JOURNAL   Anal Chem 76 (10), 2763-2772 (2004)
   PUBMED   15144186
REFERENCE   9  (bases 1 to 4456)
  AUTHORS   Figueroa,K.P. and Pulst,S.M.
  TITLE     Identification and expression of the gene for human
            ataxin-2-related protein on chromosome 16
  JOURNAL   Exp Neurol 184 (2), 669-678 (2003)
   PUBMED   14769358
REFERENCE   10 (bases 1 to 4456)
  AUTHORS   Meunier,C., Bordereaux,D., Porteu,F., Gisselbrecht,S., Chretien,S.
            and Courtois,G.
  TITLE     Cloning and characterization of a family of proteins associated
            with Mpl
  JOURNAL   J Biol Chem 277 (11), 9139-9147 (2002)
   PUBMED   11784712
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC145285.2, AC116346.2 and
            AC133550.2.
            
            On Sep 25, 2020 this sequence version replaced NM_007245.3.
            
            Summary: This gene encodes an ataxin type 2 related protein of
            unknown function. This protein is a member of the spinocerebellar
            ataxia (SCAs) family, which is associated with a complex group of
            neurodegenerative disorders. Several alternatively spliced
            transcripts encoding different isoforms have been found for this
            gene. [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ317970.1, SRR11853561.11126.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000336783.9/ ENSP00000338718.4
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-560               AC145285.2         214775-215334
            561-597             AC145285.2         217142-217178
            598-654             AC145285.2         217400-217456
            655-726             AC145285.2         217546-217617
            727-877             AC145285.2         218016-218166
            878-1002            AC145285.2         218638-218762
            1003-1094           AC116346.2         157272-157363
            1095-1295           AC116346.2         157729-157929
            1296-1471           AC116346.2         158486-158661
            1472-1582           AC116346.2         158833-158943
            1583-1777           AC116346.2         160076-160270
            1778-1849           AC116346.2         160367-160438
            1850-1920           AC133550.2         54955-55025         c
            1921-2216           AC133550.2         54488-54783         c
            2217-2286           AC133550.2         54334-54403         c
            2287-2433           AC133550.2         53631-53777         c
            2434-2506           AC133550.2         53427-53499         c
            2507-2694           AC133550.2         53149-53336         c
            2695-2824           AC133550.2         52655-52784         c
            2825-2946           AC133550.2         52443-52564         c
            2947-3156           AC133550.2         52084-52293         c
            3157-4456           AC133550.2         50610-51909         c
FEATURES             Location/Qualifiers
     source          1..4456
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p11.2"
     gene            1..4456
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /note="ataxin 2 like"
                     /db_xref="GeneID:11273"
                     /db_xref="HGNC:HGNC:31326"
                     /db_xref="MIM:607931"
     exon            1..560
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     CDS             262..3489
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ataxin 2 related protein; ataxin-2 domain protein;
                     ataxin-2-like protein"
                     /codon_start=1
                     /product="ataxin-2-like protein isoform 1"
                     /protein_id="NP_009176.2"
                     /db_xref="CCDS:CCDS10641.1"
                     /db_xref="GeneID:11273"
                     /db_xref="HGNC:HGNC:31326"
                     /db_xref="MIM:607931"
                     /translation="MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLAT
                     SAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQ
                     STGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAV
                     DAVHRKASEPAGGPRREDIVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSK
                     VNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSS
                     YTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQG
                     SGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSP
                     GPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSP
                     KSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKE
                     LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDP
                     FPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQP
                     PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP
                     TSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQ
                     QGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQ
                     PAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYAT
                     VHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLY
                     HPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGI
                     TAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGE
                     QPGQAPGFPGGADDRIREFSLAGGIWHGRAEGLQVGQDARVLGGE"
     exon            561..597
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            598..654
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            655..726
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            727..877
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            878..1002
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1094
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1095..1295
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1471
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1472..1582
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1583..1777
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1778..1849
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1850..1920
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1921..2216
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            2217..2286
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            2287..2433
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            2434..2506
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            2507..2694
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            2695..2824
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            2825..2946
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            2947..3156
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     exon            3157..4456
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4439..4444
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /note="hexamer: AATAAA"
     polyA_site      4456
                     /gene="ATXN2L"
                     /gene_synonym="A2D; A2LG; A2LP; A2RP"
                     /note="major polyA site"
ORIGIN      
        1 ggcgacgcgc acgcgcgcca gcccggctcg cgccctctcg ctttcctcca gccgcgagac
       61 cccctcccct tccgcctcgc ggcgcttcct cgcgccgcgg tcttctctct ccacccccga
      121 caccgcgggg ctccccccgc ccgcccacgg cgggccccgg ctgcccgatc cccctcgctt
      181 cccgcgctct ccagcggggc cccagccccg gccccctctc tccctccctt ctctctaatt
      241 ccccttccgg acgctgccat catgttgaag cctcagccgc tacaacagcc ctcccagccc
      301 cagcagccgc cccccacgca acaggccgtg gcccgtcggc cccccggggg caccagccct
      361 cccaacggcg gcctcccggg gccgctggcc acctctgcgg ctcctcccgg gcctccagcg
      421 gccgcctccc cctgcctggg gcctgtggcc gctgccggga gcgggctccg ccggggagcc
      481 gaaggcatct tggcgccgca gccgccgccg ccgcagcaac accaggagag gccgggggca
      541 gccgccatcg gcagcgccag gggacagagc acaggaaagg gacccccaca gtcacctgtg
      601 tttgaaggcg tctacaacaa ttccagaatg ctgcatttcc ttacagctgt tgtgggctcc
      661 acttgtgatg taaaggtgaa aaatggtacc acttatgagg gtatcttcaa gacgctaagc
      721 tcaaagtttg aactagccgt ggatgctgtg caccggaaag catctgagcc agcaggtggc
      781 cctcgtcggg aggacattgt ggacaccatg gtgtttaagc caagtgatgt catgcttgtt
      841 cacttccgaa atgttgactt caactatgct actaaagaca agttcaccga ttcagccatt
      901 gccatgaact cgaaagtgaa tggggaacac aaagagaagg tgcttcagcg ctgggagggg
      961 ggtgacagca acagcgacga ctatgacctc gagtctgaca tgtccaatgg atgggacccc
     1021 aatgaaatgt tcaagttcaa tgaggagaac tacggtgtga agactaccta tgatagcagt
     1081 ctttcttctt atacggtgcc cttagaaaag gacaactcag aagagtttcg tcagcgagag
     1141 ctgcgtgcgg cccagttggc tcgagagatt gaatcaagcc cccagtaccg cctacggatc
     1201 gccatggaga acgacgatgg gcgcactgaa gaggagaagc acagtgcagt ccagcggcag
     1261 ggctcagggc gggagagccc cagcttggca tccagggagg ggaagtatat ccctctgcct
     1321 caacgagtcc gggaaggtcc ccggggagga gttcgatgca gcagctctcg gggcggtcgg
     1381 cctggcctta gctctttgcc acctcgtggc cctcaccatc tggacaacag cagccctggc
     1441 ccaggttctg aggcccgtgg tatcaatgga ggcccttccc gcatgtcccc aaaggcacaa
     1501 cggcctctga gaggtgccaa gactctgtct tcgcccagta ataggccttc tggagaaact
     1561 tctgttccac ctcctcctgc agtgggccgg atgtatcccc cgcgttctcc caagtctgct
     1621 gcccctgccc caatctcagc ttcctgtcca gagcctccca tcggctcggc agtgccaacc
     1681 tcttcagcct ccatccctgt gacctcatca gtctcagatc ctggagtggg ctccatttct
     1741 ccagcttctc caaagatctc cctggccccc acagatgtaa aagaactctc taccaaggaa
     1801 cctgggagaa ctctggagcc ccaggagctg gctcggatag ctgggaaagt ccctggtctt
     1861 cagaatgaac agaaacgatt ccaactggaa gaactgagaa agtttggggc ccagtttaag
     1921 cttcagccca gtagctcccc tgagaacagc ctggatcctt ttcctccccg gatcttaaag
     1981 gaggagccca aaggaaagga gaaagaggtt gatggtctgt tgacttcaga gcccatgggg
     2041 tctcccgtct cctccaagac agagtccgta tcggataagg aggacaaacc acccctggca
     2101 ccatcaggag gcactgaggg gccagagcag cccccaccac cttgtccaag ccaaactggc
     2161 agccccccgg tgggcctcat caagggagaa gacaaagatg agggccctgt tgctgaacaa
     2221 gtaaagaaat caacgttgaa ccctaatgct aaggagttca atcctacaaa gcctctgctg
     2281 tctgtgaata aatccaccag taccccaact tctccggggc cccggactca ttcaactccc
     2341 tccatcccgg tgctgacagc aggccagagt gggctataca gcccccagta catctcctac
     2401 atacctcaga tccacatggg accagctgtg caggcacctc agatgtatcc atatcctgta
     2461 tccaattcag tgcctgggca gcagggcaag taccggggag caaaaggctc ccttcctccg
     2521 cagcgctcgg accaacacca gccagcctca gccccgccga tgatgcaggc cgccgcggct
     2581 gctggcccgc ctctggtggc tgccacgccc tattcttcct acatccccta caaccctcag
     2641 cagttcccag gccagccagc catgatgcag cccatggccc actacccctc acagccggtg
     2701 tttgccccca tgcttcagag caacccacgc atgctgacgt cgggcagcca tccccaggcc
     2761 atcgtgtcat cctctacccc tcagtaccct tctgcagagc agcctacccc ccaagccctt
     2821 tatgccactg ttcaccagtc ctacccacac catgccacac agctccatgc ccaccagccg
     2881 cagccggcta ccacgcctac tggaagccag ccgcagtccc agcatgcggc ccccagtcct
     2941 gtccagcatc aggcggggca ggccccacac ttgggcagtg gacagccaca gcagaatctg
     3001 taccacccag gggccctgac aggcacgccg ccctctctgc caccgggacc ttctgcccag
     3061 tcccctcaga gcagcttccc ccagccagcc gctgtgtatg ccatccacca ccagcagctg
     3121 ccccacggct tcaccaacat ggcccatgtt acccaggccc atgtccaaac tggaatcaca
     3181 gcagccccgc cccctcaccc tggggctccc cacccgcccc aggtgatgct gctgcaccca
     3241 ccccagagtc atggggggcc cccccaaggc gcggtgcccc agagtggggt gcctgcactc
     3301 tcagcttcca caccctcacc ctacccctac atcggacacc cccaaggtga gcagcctggc
     3361 caggcgcctg gatttccagg aggagccgat gacaggattc gtgagttctc attagctggg
     3421 ggaatttggc atggaagagc tgaggggctg caggtggggc aggatgcacg ggttctgggt
     3481 ggggagtgag gggtcttgga ggcagggctg tcccacaggg cgcccgccga cctgcacctg
     3541 tctgtgaagt atgtagggtg ggcagaagcc acagtcgccg ccgccagggg cttgctcctg
     3601 gctctgtcct ttgcttccct ccgtcctcgc tcagttgtga tccagcagcc cccctcccca
     3661 ctgcctcccc agctctcagt gaccccgact gtctcctgac ttagccgagg taaggtcagt
     3721 gcagcagaca gggccagact ggggtgtggg gggctgagct gggcacatga gtgagggctc
     3781 tggcttactg ggaaacagcg attgacctgt gcttctgaca gcccccgaga caccttgagg
     3841 aggccgctcc ttcccagaca cacccccacg cccccactgg acggcattgg aggaagggac
     3901 agctgcttgg gttctaatgc tcctgctctc ttctctttcc cctccaacca gttcaatctc
     3961 atccctccca gcagctcccc ttccaccccc cggggaactg aagattgtcc tggccgcgac
     4021 ctgagacctc catgagtgga gggaagagtg atctatgtct cttcccccag cagctcggac
     4081 cactcccagc cccccatccc cccgttcccc aggggagctg gggaattcct gccaagcacc
     4141 ttgaatggga ggggcctcac agagggcagg gccagggtcc agcaggggtg gggggttcct
     4201 gctctgcccc tgcccgtccc cacccagtct tgccctccca tcctctcatc tattcccccg
     4261 ctggagacgg aagatctttt attttctatt atttataact tcagacttgg gccccctgtt
     4321 ctttctttcc cattaacttg agtgacctgt gtgagagaca gacagatgcc ccacgaggat
     4381 ggctggacaa ggacttttac tttttattac ataaaaatat taaaaaataa ataaaaaaaa
     4441 taaaatttta aactaa
//
