LOCUS       NM_001198879            5504 bp    mRNA    linear   PRI 29-OCT-2022
DEFINITION  Homo sapiens ATP5MF-PTCD1 readthrough (ATP5MF-PTCD1), mRNA.
ACCESSION   NM_001198879
VERSION     NM_001198879.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5504)
  AUTHORS   Prakash T, Sharma VK, Adati N, Ozawa R, Kumar N, Nishida Y,
            Fujikake T, Takeda T and Taylor TD.
  TITLE     Expression of conjoined genes: another mechanism for gene
            regulation in eukaryotes
  JOURNAL   PLoS One 5 (10), e13284 (2010)
   PUBMED   20967262
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC073063.12, AK295912.1 and AC004922.2.
            
            On Jun 2, 2019 this sequence version replaced NM_001198879.1.
            
            Summary: This locus represents naturally occurring read-through
            transcription between the ATP5J2 (ATP synthase, H+ transporting,
            mitochondrial Fo complex, subunit F2) and PTCD1 (pentatricopeptide
            repeat domain 1) genes on chromosome 7. The read-through transcript
            encodes a fusion protein that shares sequence identity with each
            individual gene product. [provided by RefSeq, Nov 2010].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.216817.1, AK295912.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            readthrough transcript :: includes exons from GeneID 9551, 26024
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AC073063.12        52311-52313
            4-445               AK295912.1         1-442
            446-446             AC073063.12        83508-83508
            447-2120            AK295912.1         444-2117
            2121-5504           AC004922.2         11656-15039
FEATURES             Location/Qualifiers
     source          1..5504
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q22.1"
     gene            1..5504
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /note="ATP5MF-PTCD1 readthrough"
                     /db_xref="GeneID:100526740"
                     /db_xref="HGNC:HGNC:38844"
     exon            1..39
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..2276
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /note="ATP5J2-PTCD1 read-through transcript; ATP5J2-PTCD1
                     readthrough"
                     /codon_start=1
                     /product="ATP5J2-PTCD1 fusion protein"
                     /protein_id="NP_001185808.1"
                     /db_xref="GeneID:100526740"
                     /db_xref="HGNC:HGNC:38844"
                     /translation="MASVVPVKDKKLLEVKLGELPSWILMRDFSPSGIFGAFQRGPGG
                     TGKPEMDFVRLARLFARARPMGLFILQHLDPCRARWAGGREGLMRPMWAPFSSSSSQL
                     PLGQERQENTGSLGSDPSHSNSTATQEEDEEEEESFGTLSDKYSSRRLFRKSAAQFHN
                     LRFGERRDEQMEPEPKLWRGRRNTPYWYFLQCKHLIKEGKLVEALDLFERQMLKEERL
                     QPMESNYTVLIGGCGRVGYLKKAFNLYNQMKKRDLEPSDATYTALFNVCAESPWKDSA
                     LQSALKLRQQLQAKNFELNLKTYHALLKMAAKCADLRMCLDVFKEIIHKGHVVTEETF
                     SFLLMGCIQDKKTGFRYALQVWRLMLSLGLQPSRDSYNLLLVAARDCGLGDPQVASEL
                     LLKPREEATVLQPPVSRQRPRRTAQAKAGNLMSAMLHVEALERQLFLEPSQALGPPEP
                     PEARVPGKAQPEVDTKAEPSHTAALTAVALKPPPVELEVNLLTPGAVPPTVVSFGTVT
                     TPADRLALIGGLEGFLSKMAEHRQQPDIRTLTLLAEVVESGSPAESLLLALLDEHQVE
                     ADLTFFNTLVRKKSKLGDLEGAKALLPVLAKRGLVPNLQTFCNLAIGCHRPKDGLQLL
                     TDMKKSQVTPNTHIYSALINAAIRKLNYTYLISILKDMKQNRVPVNEVVIRQLEFAAQ
                     YPPTFDRYQGKNTYLEKIDGFRAYYKQWLTVMPAEETPHPWQKFRTKPQGDQDTGKEA
                     DDGCALGGR"
     exon            40..147
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /inference="alignment:Splign:2.1.0"
     exon            148..626
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /inference="alignment:Splign:2.1.0"
     exon            627..767
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /inference="alignment:Splign:2.1.0"
     exon            768..986
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1088
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1910
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1911..2093
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /inference="alignment:Splign:2.1.0"
     exon            2094..5504
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3110..3115
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /note="hexamer: AAGAAA"
     regulatory      3116..3121
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /note="hexamer: AAGAAA"
     polyA_site      3121
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /note="major polyA site"
     polyA_site      3135
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
     regulatory      3430..3435
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
                     /note="hexamer: AGTAAA"
     polyA_site      3457
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
     polyA_site      4783
                     /gene="ATP5MF-PTCD1"
                     /gene_synonym="ATP5J2-PTCD1"
ORIGIN      
        1 ggcacagcgg acaccaggac tccaaaatgg cgtcagttgt accagtgaag gacaagaaac
       61 ttctggaggt caaactgggg gagctgccaa gctggatctt gatgcgggac ttcagtccta
      121 gtggcatttt cggagcgttt caaagaggcc ctggagggac aggaaagcca gaaatggact
      181 tcgtgagact cgctcgactg ttcgccaggg cccgccccat gggactgttc atcctgcaac
      241 acctggaccc ctgtagagcc aggtgggcag gaggcaggga ggggctgatg cggccaatgt
      301 gggcgccctt cagcagctcc tcctctcagc tgcccctcgg ccaggagcgt caggaaaaca
      361 cgggcagcct gggctctgac ccgagccact ccaactccac ggccacgcag gaagaagacg
      421 aggaggagga ggagagtttt gggaccctct ctgacaaata ctcctcccgg agactattcc
      481 gcaaatccgc agcccagttc cataacctgc ggtttgggga acggagagat gagcaaatgg
      541 aaccggagcc caaattatgg cgaggccgga gaaacacccc gtactggtac ttcttgcagt
      601 gcaaacacct gatcaaggaa gggaagctgg ttgaagccct ggacctgttt gagaggcaga
      661 tgctgaagga ggagcgattg cagcccatgg agagcaacta cacggtgctg attgggggct
      721 gcgggcgggt tggctacctg aagaaggcct tcaacctcta caaccagatg aaaaagcggg
      781 acctggagcc ctcggacgcc acctacacgg ccctgttcaa cgtctgtgcc gagtccccct
      841 ggaaggactc agctctacag agcgccctga agctccggca gcagctgcag gccaaaaact
      901 tcgagctcaa cttgaaaaca taccacgcgc tgctgaagat ggctgccaag tgcgcagacc
      961 ttaggatgtg cctcgatgtg ttcaaggaaa tcatccacaa agggcacgtg gtcacagagg
     1021 agaccttcag tttcctgctc atgggctgca tccaagacaa gaagacaggc ttccggtacg
     1081 ccctccaggt gtggcggctg atgctgagtc tagggctaca gccgagccgg gacagctaca
     1141 acctgctgtt ggtggcagct cgggactgtg gcctagggga cccccaggtg gcctcagagc
     1201 tgcttctgaa gcccagggag gaggcgactg tgcttcagcc cccagtgagc aggcagcggc
     1261 caaggaggac agcccaggcc aaggcaggca acctcatgtc agccatgctg catgtggagg
     1321 ccctggagag gcagctgttt ctggaacctt ctcaggcact tgggcctcca gagcctccgg
     1381 aagccagagt gcccggcaag gcccaaccag aggtggatac taaggcagag cccagccaca
     1441 cagcagccct caccgcagtg gccctgaagc cacctcccgt ggagctggaa gtcaacctcc
     1501 tgacccccgg ggccgttccc cctacagtgg tctcctttgg aacggtgacc accccagctg
     1561 accggctggc cttgataggg ggcctggagg gcttcctgag caagatggca gagcacaggc
     1621 agcagcccga catcaggacc ctcacgctac tggccgaggt ggtggagtcc gggagtcctg
     1681 cagagtcctt gctgctggcc ctcctggatg agcaccaggt agaggccgac ctgacattct
     1741 ttaacacgct ggtgagaaag aagagcaagc tgggagacct ggagggggcc aaggcgctgt
     1801 tgccggtcct ggcaaagagg ggcctcgtcc ccaacctgca gacattctgc aacctggcca
     1861 tcgggtgcca caggccgaag gacggtctac agcttctcac agacatgaag aagtcccagg
     1921 tgacccccaa cactcacatc tacagtgccc tcatcaacgc ggccatcagg aagctgaact
     1981 acacctatct catcagcatc ttgaaggaca tgaagcagaa cagggtcccg gtgaacgaag
     2041 tggtcatccg ccagctggag tttgcagccc agtaccctcc cacctttgac cggtaccaag
     2101 ggaagaacac ctacctggag aagattgacg gcttccgagc ctattacaag cagtggctga
     2161 cagtgatgcc cgcagaggaa accccgcacc cctggcagaa gttccggacc aagccccagg
     2221 gggaccagga caccggcaag gaggctgatg acggatgtgc ccttgggggc aggtgatggg
     2281 agcacagctg gaacaatgtg ctcggccccc agtgctctgt gggagcccca ggacaagtga
     2341 gctggtgtca cctcctgcct gggggaagag ccaggccctg aggaacagcc gcagcgtgtc
     2401 acaggtgttg gtgaggacac acactaggcc caaggtgcct gtgctcccag caggtccaag
     2461 tgcagctcca gccacctttg cgtgtcacct tcacgggact tccagctcca gctacctttg
     2521 tgtgtcacct cacacaccac aagggggctg gggcatctgg tccctggggc ctgggccgcc
     2581 ccgccgggtt ccataggccg atgctctgaa agaagagacg tggggctcga gagatttaaa
     2641 gattttattt ttacaaatca cagctgatag acagcgaagc cttccccata gagaccgtgc
     2701 tccaactcgg gcctggggca ctgctcgctg ctcccaggaa gggggtggcg tgacaggcag
     2761 gaacctgcga agtccagagt ccagggtgga gcgcgccagc ctcagccaga gcagccacga
     2821 cagccacagt gtgtgcactc gatgatgcgg ccctgcaacg gaggaggaca gtgagacgat
     2881 gccactgcgc cacgctcgcc cctgcacact cacatatgtg gcaaccctcc cacgaaggac
     2941 ctgccaccat gccatatagg gacacacctc agaaaccctt ccttgacagc tctggacagg
     3001 gaaaatttgg ctccctcatg aaggtagaac cagctgctgt tgacaccgag gttacatctg
     3061 tatgtctatt tataatatgt tctgcaaatc caacacacgt ttgccaatca agaaaaagaa
     3121 atcggtgtga atgagtctcg ttattctgct aagtgagcat gacagaccct gcgatgagca
     3181 gacgtggctc tgctactgtt tggggacttc aggggggcct ctgggctggt acactctggt
     3241 gggggaagag ggcaggagac tatgcacttg agtcacaccc ttctggccca gagcccccca
     3301 gaaagaaggg tcttgtcccc caggcctggt gcggcccaac acttggccag ccagaaagcc
     3361 ctagaacagt ggcttgtgtt tattttactt tttcaagttc tttttttgga agaacaagac
     3421 catagtttaa gtaaacagga tcctctggtg aaacccaggt aagtctacag cgggctgttt
     3481 tggccacagg gctgaagcag caccccagcc caccagcccc tgacctggac tccttgtgga
     3541 atctgggcac tcagaggaag ggggcttctg ccactctgcc acctgtccct gcctccatca
     3601 gaaaaccaac accccagtct tccgtcgggg aggcggccct tgctcgcccc cactgctcag
     3661 tacccaagtc ctcagcatcc agccacagct ctccattgtc agtctcactg cagcataaag
     3721 gggactcatg tgaagaggcc cctgtgtgga gctggggaaa agaaggccag gctggcagat
     3781 gggcggtggg gccaacaact gtgctgaggg gctgcactga gcggccactg ctgtgactct
     3841 gcctcgggcc acagctgcct ttcagagggg cttggaaccg gatggagctc agctcctgtc
     3901 cctcagcacc actcctgagg cgcctggcct aggagtggta cttggaacag aaagttctga
     3961 aagaagaaac acagtgggct gggcgcagta gctcatgcct gtaatcccgg cactttggga
     4021 ggctgaggcg ggtggatcac ctgaggtcgg gagttcgaga ccagcctgag caacattgag
     4081 aaaccccgtc tctactaaaa atacaaaatt agccaggcgt ggtggtgcat gcctgtagtc
     4141 ccagctactc aggaggatga ggcaggagaa ccgcttgaac ccgggaggtg gaggttgcag
     4201 tgagccaaga tggcatcact gcactccagc ctgggcgaca aagcaagact ccgtcttggg
     4261 ggggcgggaa agatagtgat ggtaatgtta aagtatcact gtgaggactg aaagggacag
     4321 gaactcactg gttgtccttc cctgatgtca ccctgccacc accttgggat tagggctccc
     4381 caccaccatt tcctaagtga ggaaaggggt tcagtaattt gcccaaaagt ggagttgaga
     4441 ttgaccccag acctaacaaa cacacagcca cacgctgcct cacatggatt cctgaataca
     4501 gggacccact cccacgaggg agagccagca ggacatccag ggacaaaacg acattccagc
     4561 ccaaccaaat aacataagat cccttgcagt cgactaaggc agaattttga gctgaaaaca
     4621 acaccaagct tgagtgtcag acattaccac ttccagcttg cttttgggca cgcggcagat
     4681 gcagttcgtc ccgaagttgg tgtcccgtgt ctgaatgcac cgcaggcagc acaagttctc
     4741 atatccttgc tttttccatt ttgcaatcag gtttttgtct gcatagcctt ctttaataca
     4801 atattcatag agttctgtca aaaagatggg gaaagagcat caggccatgg tctaaaaacc
     4861 ttccccaccc ttgatcaaaa aaagcattca ggccgggtgc agtggctcac acctgtaatc
     4921 ccagcacttt gggaggccga ggcaggcgga tcacctgagg tcaggagttc aggaccagcc
     4981 cggccaacat ggtaaaaccc cgtctctact aaaaatacaa aaattactcg ggcgtggtag
     5041 cagctgtaat cccagctact taggaggctg aggcaggaga atcacttgaa cccaggaggc
     5101 ggaggttgta gtgacctgag gtcgtgccac tggactccag cctgggtgac agcgaaactc
     5161 catctcaaaa aaaaaaaggc attcagtatt gcaacgggac agtccttgga ggaggaacaa
     5221 aaaaaaaaag tacttaggcc aggcaaggtg cctcacacct gtaatcccag cacttttgga
     5281 agccaacgcc agaggatcat ttgagttaag aaaccagcct gggccaaggg cccatctcca
     5341 caaaaaattt aaaaattagc tgggtgtggt ggtgcacacc tgtagtcaca gctactcagg
     5401 aggttgaggt gagaggatcc cttgagccca gaaggttgag gctgcagtga gccatcattg
     5461 caccactgca ctccagcctg tggaacagag caagaccctg tttc
//
