LOCUS       NM_015459               6899 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens atlastin GTPase 3 (ATL3), transcript variant 1, mRNA.
ACCESSION   NM_015459 NM_175893
VERSION     NM_015459.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6899)
  AUTHORS   Bryce,S., Stolzer,M., Crosby,D., Yang,R., Durand,D. and Lee,T.H.
  TITLE     Human atlastin-3 is a constitutive ER membrane fusion catalyst
  JOURNAL   J Cell Biol 222 (7) (2023)
   PUBMED   37102997
  REMARK    GeneRIF: Human atlastin-3 is a constitutive ER membrane fusion
            catalyst.
REFERENCE   2  (bases 1 to 6899)
  AUTHORS   Mohammadi,S., Jafari Khamirani,H., Baneshi,M., Kamal,N.,
            Manoocheri,J., Saffar,M., Dianatpour,M., Tabei,S.M.B. and
            Dastgheib,S.A.
  TITLE     A novel nonsense variant in the ATL3 gene is associated with
            disturbed pain sensitivity, numbness of distal limbs and muscle
            weakness
  JOURNAL   Ann Hum Genet 87 (4), 147-157 (2023)
   PUBMED   36856139
  REMARK    GeneRIF: A novel nonsense variant in the ATL3 gene is associated
            with disturbed pain sensitivity, numbness of distal limbs and
            muscle weakness.
REFERENCE   3  (bases 1 to 6899)
  AUTHORS   Cintra,V.P., Dohrn,M.F., Tomaselli,P.J., Figueiredo,F.B.,
            Marques,S.E., Camargos,S.T., Barbosa,L.S.M., P Rebelo,A., Abreu,L.,
            Danzi,M., Marques,W. Jr. and Zuchner,S.
  TITLE     Rare mutations in ATL3, SPTLC2 and SCN9A explaining hereditary
            sensory neuropathy and congenital insensitivity to pain in a
            Brazilian cohort
  JOURNAL   J Neurol Sci 427, 117498 (2021)
   PUBMED   34090020
  REMARK    GeneRIF: Rare mutations in ATL3, SPTLC2 and SCN9A explaining
            hereditary sensory neuropathy and congenital insensitivity to pain
            in a Brazilian cohort.
REFERENCE   4  (bases 1 to 6899)
  AUTHORS   Liu,N., Zhao,H., Zhao,Y.G., Hu,J. and Zhang,H.
  TITLE     Atlastin 2/3 regulate ER targeting of the ULK1 complex to initiate
            autophagy
  JOURNAL   J Cell Biol 220 (7) (2021)
   PUBMED   33988678
  REMARK    GeneRIF: Atlastin 2/3 regulate ER targeting of the ULK1 complex to
            initiate autophagy.
REFERENCE   5  (bases 1 to 6899)
  AUTHORS   Lee,S.H., Hadipour-Lakmehsari,S., Murthy,H.R., Gibb,N., Miyake,T.,
            Teng,A.C.T., Cosme,J., Yu,J.C., Moon,M., Lim,S., Wong,V., Liu,P.,
            Billia,F., Fernandez-Gonzalez,R., Stagljar,I., Sharma,P.,
            Kislinger,T., Scott,I.C. and Gramolini,A.O.
  TITLE     REEP5 depletion causes sarco-endoplasmic reticulum vacuolization
            and cardiac functional defects
  JOURNAL   Nat Commun 11 (1), 965 (2020)
   PUBMED   32075961
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6899)
  AUTHORS   Kornak,U., Mademan,I., Schinke,M., Voigt,M., Krawitz,P., Hecht,J.,
            Barvencik,F., Schinke,T., Giesselmann,S., Beil,F.T.,
            Pou-Serradell,A., Vilchez,J.J., Beetz,C., Deconinck,T.,
            Timmerman,V., Kaether,C., De Jonghe,P., Hubner,C.A., Gal,A.,
            Amling,M., Mundlos,S., Baets,J. and Kurth,I.
  TITLE     Sensory neuropathy with bone destruction due to a mutation in the
            membrane-shaping atlastin GTPase 3
  JOURNAL   Brain 137 (Pt 3), 683-692 (2014)
   PUBMED   24459106
  REMARK    GeneRIF: ATL3 is implicated in the structural organization of
            intracellular organelles, which may be critical to axonal survival.
REFERENCE   7  (bases 1 to 6899)
  AUTHORS   Chang,J., Lee,S. and Blackstone,C.
  TITLE     Protrudin binds atlastins and endoplasmic reticulum-shaping
            proteins and regulates network formation
  JOURNAL   Proc Natl Acad Sci U S A 110 (37), 14954-14959 (2013)
   PUBMED   23969831
REFERENCE   8  (bases 1 to 6899)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   9  (bases 1 to 6899)
  AUTHORS   Hu,J., Shibata,Y., Zhu,P.P., Voss,C., Rismanchi,N., Prinz,W.A.,
            Rapoport,T.A. and Blackstone,C.
  TITLE     A class of dynamin-like GTPases involved in the generation of the
            tubular ER network
  JOURNAL   Cell 138 (3), 549-561 (2009)
   PUBMED   19665976
REFERENCE   10 (bases 1 to 6899)
  AUTHORS   Rismanchi,N., Soderblom,C., Stadler,J., Zhu,P.P. and Blackstone,C.
  TITLE     Atlastin GTPases are required for Golgi apparatus and ER
            morphogenesis
  JOURNAL   Hum Mol Genet 17 (11), 1591-1604 (2008)
   PUBMED   18270207
  REMARK    GeneRIF: A family of human GTPases, atlastin-2 and -3 that are
            closely related to atlastin-1 are described.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC077727.1 and AP000753.4.
            This sequence is a reference standard in the RefSeqGene project.
            
            On May 17, 2019 this sequence version replaced NM_015459.4.
            
            Summary: This gene encodes a member of a family of dynamin-like,
            integral membrane GTPases. The encoded protein is required for the
            proper formation of the network of interconnected tubules of the
            endoplasmic reticulum. Mutations in this gene may be associated
            with hereditary sensory neuropathy type IF. Alternatively spliced
            transcript variants that encode distinct isoforms have been
            described. [provided by RefSeq, Feb 2014].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer protein (isoform 1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CR936784.1, SRR1660803.28769.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2467150 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000398868.8/ ENSP00000381844.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1820              BC077727.1         246-2065
            1821-6899           AP000753.4         48866-53944         c
FEATURES             Location/Qualifiers
     source          1..6899
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q13.1"
     gene            1..6899
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /note="atlastin GTPase 3"
                     /db_xref="GeneID:25923"
                     /db_xref="HGNC:HGNC:24526"
                     /db_xref="MIM:609369"
     exon            1..87
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..1667
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /note="isoform 1 is encoded by transcript variant 1;
                     atlastin-3"
                     /codon_start=1
                     /product="atlastin-3 isoform 1"
                     /protein_id="NP_056274.3"
                     /db_xref="CCDS:CCDS41663.1"
                     /db_xref="GeneID:25923"
                     /db_xref="HGNC:HGNC:24526"
                     /db_xref="MIM:609369"
                     /translation="MLSPQRVAAAASRGADDAMESSKPGPVQVVLVQKDQHSFELDEK
                     ALASILLQDHIRDLDVVVVSVAGAFRKGKSFILDFMLRYLYSQKESGHSNWLGDPEEP
                     LTGFSWRGGSDPETTGIQIWSEVFTVEKPGGKKVAVVLMDTQGAFDSQSTVKDCATIF
                     ALSTMTSSVQIYNLSQNIQEDDLQQLQLFTEYGRLAMDEIFQKPFQTLMFLVRDWSFP
                     YEYSYGLQGGMAFLDKRLQVKEHQHEEIQNVRNHIHSCFSDVTCFLLPHPGLQVATSP
                     DFDGKLKDIAGEFKEQLQALIPYVLNPSKLMEKEINGSKVTCRGLLEYFKAYIKIYQG
                     EDLPHPKSMLQATAEANNLAAAASAKDIYYNNMEEVCGGEKPYLSPDILEEKHCEFKQ
                     LALDHFKKTKKMGGKDFSFRYQQELEEEIKELYENFCKHNGSKNVFSTFRTPAVLFTG
                     IVALYIASGLTGFIGLEVVAQLFNCMVGLLLIALLTWGYIRYSGQYRELGGAIDFGAA
                     YVLEQASSHIGNSTQATVRDAVVGRPSMDKKAQ"
     exon            88..302
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /inference="alignment:Splign:2.1.0"
     exon            303..446
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /inference="alignment:Splign:2.1.0"
     exon            447..551
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /inference="alignment:Splign:2.1.0"
     exon            552..602
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /inference="alignment:Splign:2.1.0"
     exon            603..659
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /inference="alignment:Splign:2.1.0"
     exon            660..752
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /inference="alignment:Splign:2.1.0"
     exon            753..891
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /inference="alignment:Splign:2.1.0"
     exon            892..1019
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1076
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /inference="alignment:Splign:2.1.0"
     exon            1077..1148
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /inference="alignment:Splign:2.1.0"
     exon            1149..1580
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /inference="alignment:Splign:2.1.0"
     exon            1581..6899
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6881..6886
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /note="hexamer: AATAAA"
     polyA_site      6899
                     /gene="ATL3"
                     /gene_synonym="HSN1F"
                     /note="major polyA site"
ORIGIN      
        1 ctctgcaccc ctgctgcttc tgctttgaag gcggaggctc catgttgtcc cctcagcgag
       61 tggcagcagc tgcctcaaga ggagcagatg atgccatgga gagcagcaag cctggtccag
      121 tgcaggttgt tttggttcag aaagatcaac attcctttga gctagatgag aaagccttgg
      181 ccagcatcct cttgcaggac cacatccgag atcttgatgt ggtggtggtt tcagtggctg
      241 gtgccttccg aaagggcaag tccttcattc tggattttat gctacgatac ttatattctc
      301 agaaggaaag tggccattca aattggttgg gtgacccaga agaaccgtta acaggatttt
      361 cctggagagg gggatctgat ccagaaacca ctgggattca aatctggagt gaagttttca
      421 ctgtggagaa gccaggtggg aagaaggttg cagttgttct gatggatacc cagggggcat
      481 ttgacagcca gtcaactgtg aaagactgtg ctaccatctt tgctctaagc actatgacta
      541 gttctgttca gatttataat ttatctcaga acattcaaga agatgatctt caacagctgc
      601 agctcttcac agaatacggt cgtctggcaa tggatgaaat tttccaaaag cctttccaga
      661 cactgatgtt tttggttaga gattggagtt tcccttatga atatagctat ggactccaag
      721 gaggaatggc atttttggat aagcgtttac aggtgaagga acatcaacat gaagaaattc
      781 agaatgttcg aaatcacatt cactcatgtt tctccgatgt cacctgcttt ctcttaccac
      841 atccaggact ccaggtggcc acaagccctg actttgatgg gaaattaaaa gatattgctg
      901 gtgaattcaa agagcagtta caggcactga taccgtatgt attaaaccca tctaagttaa
      961 tggaaaagga gatcaatggc tcaaaggtca cctgtcgggg actactggag tattttaagg
     1021 catatattaa aatttatcaa ggagaagatc tgcctcaccc caagtccatg cttcaggcca
     1081 ctgctgaagc caacaactta gcagctgcag cctctgccaa ggacatttat tataacaaca
     1141 tggaagaggt ttgtggggga gagaaacctt atttgtctcc agacattcta gaggagaagc
     1201 actgtgaatt caaacaactt gctctggacc attttaagaa gaccaagaag atgggtggga
     1261 aggatttcag ctttcgttac cagcaggagc tggaggagga aatcaaggaa ttatatgaga
     1321 acttctgcaa gcacaatggt agcaagaacg tcttcagcac cttccgaacc cctgcagtgc
     1381 tgttcacggg cattgtagct ttgtacatag cctcaggcct cactggcttc ataggtcttg
     1441 aggttgtagc ccagttgttc aactgtatgg ttggactact gttaatagca ctcctcacct
     1501 ggggctacat caggtattct ggtcaatatc gtgagctggg cggagctatt gattttggtg
     1561 ccgcatatgt gttggagcag gcttcttctc atatcggtaa ttccactcag gccactgtga
     1621 gggatgcagt tgttggaaga ccatccatgg ataaaaaagc tcaatagcat cttaacgtga
     1681 agatcaaaca agaacacaac aagcccctac tgatttctgg gtttctgcca cggccacagg
     1741 ttcatatcca gaggaatggc agatctgaga cgatccagga agagctaaaa catggccctg
     1801 taataaatga gcagacctct cctgtggttt caaattatta aacacacttc catttctctt
     1861 ggaagcattt cttttccttg ctgttataga tgcaagcctg tgtctatttt catattactc
     1921 tgctttgtgc actttatgga ggaggaagct agaggaaaaa tggaaatgca gcttttaagt
     1981 tctttatgtg ccacttagtg ccttttaaga ttgattccat ggttttgcac acacgatggg
     2041 gaggggatgg aggataacct catgaaaggt gccgttttcg ggtgaaactt gacatttctt
     2101 ttatacttta ctcttttgag aaggattctt tttttttttt tttttttttt tgagttggag
     2161 tctcgctctg tcaccaggct tgagtgcagt ggtgtgatct tggctcactg caacctctgc
     2221 ctgccgggtt caagcagttc tcctgcctca gcctcccaag tagctgggac tacaggtgta
     2281 cgccaccata cccagctaat ttttttgtat ttttagtaga gatggggttt caccatgttg
     2341 gccaggatgg tcttggtctc ttgaccttgt gatccgcctg cccgccttgg cctcccaaag
     2401 tgctgggatt acaggcgtga gccaccgtgc ccggccaaga aggattcctt ttttaaaagt
     2461 ttacagaact tggagaaact tcagaactaa agactaactg aaaatgatgt cattacactc
     2521 aaaaaaaatt tacaataggg aatcctgttg ccacatagtg tggaaaaatc atgtcatatt
     2581 taaatatacc atactctgaa atgtgaggtt tttacccagt aggctgacag ttttgttgca
     2641 acttgctcta tttttttttt ttttttggtc cctatagctt ctttctagaa aaagaggcaa
     2701 acgtgccttg aaaagccaga gtggctcata ataaaaggaa tgcgctagat acttcaagaa
     2761 aaaagctaag tttaaatgaa ccatgtgacc tctgataagt cacttgaact tgtgccttgg
     2821 tcaggttcac tgtaggttta catatgtatg tatgttttac acaactcttg taattgtcat
     2881 ttgaggggtt ttgtttttga gagttctgca taagaacaga actttattaa ggattagagg
     2941 gaagatacaa atattactgc gtttaattga tgtctaattt catgtggctt agcagcaatt
     3001 aataacctga tttaaggtct ttattcagaa tgttaatttg cattctctgc cgtgtctaat
     3061 gttcttaata atgaagctaa aattaaccca ttttatttag tgaattatct atttaatttt
     3121 actttggcta gtctggtagc tttaagatag ctttgcctta gcaaggatca aagtcctacc
     3181 caaatataaa aaatatctag aagtatctaa gagttctttt tttctattta ccttgattag
     3241 gagataaaag ttttatctgt tagttgcttt tccttttgga attattgtgg attttaaaac
     3301 ttaaaacttg cctgcaagta tttatataaa cattcaggta tataagcctt aatttctaag
     3361 ataatttaac ttttgttatg ggagggaggt aagagtgtaa attttatata catgaaggta
     3421 agatctgagt gtaaacttta catacatgaa gtatgaatgg aaggtagaaa aaaagtccct
     3481 tttcgcatgt aatctcttta tcaaagaatt ttcttttgac actttaccac tgaagtattt
     3541 ttgtaagtcc taaattcgca gcatattgtt tcatatttat atgccatctt gcaaatagtt
     3601 cttgctattt tattcactgc tgttacactt tagaaaaatt ccagcttgtt tacttgcatt
     3661 tatcagtgat gccaaccaag ctttgactgt taacttgaaa gcttgcttct gaaatgttgg
     3721 tgcattttca ggtgacctct tatctctctg aaagttcata cctattagca ggctctgtaa
     3781 atattgacat acttagcttt taatacattc tataagtaaa tttatagatt tcagaataac
     3841 ttaaaaaatt taatggtaag aaggggtgat gtgtcgaaaa ctcatactaa agtattaggt
     3901 cactttaaaa aaagtgataa tgtatgattt aatgaaatct taagattcag ttactattta
     3961 aattcaccat ttctgttttg gtcttataaa gagaccttgg tttaattatc cagaggaagt
     4021 cctcttcacc attttttttt tttcttagtt ctgcttctgg aaagtgtttt ataaagtttt
     4081 ctcagtgagg gttcttaaga gttttctttg gcctcttttc tctcaacagt aaattgatga
     4141 ttttatatca gctttttcaa taaaagatgc attatcatta ctggctataa atcatcctgg
     4201 ggagatttat aaccaggtta aaaataatat cttttacttc tctcaccttt tacttgtggt
     4261 tcagatgctc agactgtgcc tgtttgcgtc gtgtctgttg ctctgccgct ttccatgcag
     4321 gcatttttaa ttttacacaa tcctaacaat atatggaact cattcctatg aatatataaa
     4381 aggaggcttc caaaattttc tattaaaata tttcaggata aattaagtgt tgataatttg
     4441 aaaaaataat ttcaatgagc tgcttatagt aaaaatggta gaatcagagt tttcattctt
     4501 tgagaaatct ttctgtaaga ttggctcata gataaaatga gacaaactac tatgtatgat
     4561 aaaacacctt cagagtcatg ccttgtttta ttttatttta ttttttgaga cagaggtctc
     4621 gctctgtcgc ccaggttgga gtgcagtggt gcaatctcgc tcactgcaac ctccacctcc
     4681 caggttcaag cgattctcct gtctcagctt cctgagtagc tgggactaca ggtgtacacc
     4741 accacgcctg gctaattttt gtttttttac tagaggtggg gttttgccat gttggccagg
     4801 ctggtctcaa actcctgacc tcaggtgatc cactcccccc agcctcccaa agtgctggga
     4861 ttacaggcat gagccacccc gcccagctga gtcatgcctt attttcgtag tataccaaga
     4921 aatgttctat ggaagtttac gttttaacac ctcttttata cttggtaaaa ttgcctgtgt
     4981 ttcgctttat tccttttttt ttttgagacg gactcttgta ctgtcaccca ggctgaagtg
     5041 cagtggcgca atcttggctc actacaacct ccgcctcctg ggttcaagtg attcttttgc
     5101 ctcagcctcc caagtagcag ggattacagg catgtgccac cacacccggc ttatttttgt
     5161 atttttagta gagacagggc ttcgccatgt tgaccaggct ggtctcaact cctctgggaa
     5221 tccgcctgtc ttggccttcc agggtgctgg gattacaggc gtgagccact ggaacctggc
     5281 cttgttttgc tttatttttt ctcttacatg aagtaaagcg ctttggtcaa acacacaaaa
     5341 atactgcctt gtactggtgg ttggtttcat tagtggatca cacacagtgt tctacttggc
     5401 ttgtaaaatg gtgccttgga tagggtgagt ttggataagt atgtatgtat gtatgagtta
     5461 tagcaaaatt aagtagattg aatcaagtcc atgcaaaagc aataaaacag ttttaatttt
     5521 ttaatttttt aaaaattaaa actttaataa aacagttttt aattttttgc taggttcttt
     5581 taaaaaatga tgtaacttac atggaagtct tcacaggact tttttctttc ctggaactat
     5641 tgaaatgtaa tttaggatga tttgatcttc catctcaagt tgtcaacatg gctgtgtcat
     5701 tctggcttac atatgtttta tttaacaaaa ttctagtcaa gggataaggg cataatgaag
     5761 acaagcttca gttatgaaag tacaaactat ttgtgtgatt aatttttaaa aatgacatta
     5821 agaagcccat tgtaaaataa tatttgcagt caaatggttt ttcttgctgt aagtcctgtt
     5881 gtagctatgt ttagggtagt ggttctcatc taccttggag tgcataagac ttacctagca
     5941 ggcttgttta aaaagttcag attcctagct ttgtacccag ggattgcctc aggtggtatg
     6001 ggctgtggtc ctggagtcat cacttttata aatagtggtt cagagaccac agagagagac
     6061 tgcttcatcg aatgggaagt accaaggaga aagtacaatt cagtattgtc tggaggcaag
     6121 tggacacttt gtacctgagg tttagaatag gtggtctctt gccagtacaa tccccaggcg
     6181 ttttctgtgt tcagaagtag taagaatgcc tttaattcag aggattatct aagctcttta
     6241 aagctgtttt tctccattgt catagtgcct tctctgaaaa atgaatgtac aggtatccta
     6301 ttttctaatg taattaggat tttttaaaag caatttttga tagtttttct tttaaaaagt
     6361 aaaattcagc actgtgactt gaacccccaa atctttcaca tacaggtgaa acattaagcc
     6421 acaaataaaa ataatgaaca agaaagaaga caagatccta attcctgtca ttagtgacct
     6481 aagtacccca tatcagaaac tttgcaaaac agatctaggg acagaagggc tttgaaagac
     6541 atttttcttt ggggcaaatt tcgtgtgcca gaactacagt ttaaatgttt ttatgagcaa
     6601 gggaaggtag cattgattcc catagctttc taattagata catgctgtca tggatgtaag
     6661 ccttaaagga gttaatacta atcttgtaca tacacaaatt ttcctcaggt ttttttattt
     6721 taaaaaatga tttgttaaaa gtactgtctg ctagaccctt gcctttgagt ggctttgaaa
     6781 cttaatatag tttttaaaaa gtgcaatggg atgagattat gctattagta tattaaaagc
     6841 atgtttctgt tttactccaa tttgtaagat catttaatgg aataaagatc acaacacca
//
