LOCUS       XM_011536563            4448 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens autophagy related 14 (ATG14), transcript
            variant X1, mRNA.
ACCESSION   XM_011536563
VERSION     XM_011536563.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000014.9) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011536563.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4448
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
     gene            1..4448
                     /gene="ATG14"
                     /gene_synonym="ATG14L; BARKOR; KIAA0831"
                     /note="autophagy related 14; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 9
                     ESTs, 347 long SRA reads, and 93% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     37 samples with support for all annotated introns"
                     /db_xref="GeneID:22863"
                     /db_xref="HGNC:HGNC:19962"
                     /db_xref="MIM:613515"
     CDS             81..1220
                     /gene="ATG14"
                     /gene_synonym="ATG14L; BARKOR; KIAA0831"
                     /codon_start=1
                     /product="beclin 1-associated autophagy-related key
                     regulator isoform X1"
                     /protein_id="XP_011534865.1"
                     /db_xref="GeneID:22863"
                     /db_xref="HGNC:HGNC:19962"
                     /db_xref="MIM:613515"
                     /translation="MSCKMRIEQLKQTICKGNEEMEKNSEGLLKTKEKNQKLYSRAQR
                     HQEKKEKIQRHNRKLGDLVEKKTIDLRSHYERLANLRRSHILELTSVIFPIEEVKTGV
                     RDPADVSSESDSAMTSSTVSKLAEARRTTYLSGRWVCDDHNGDTSISITGPWISLPNN
                     GDYSAYYSWVEEKKTTQGPDMEQSNPAYTISAALCYATQLVNILSHILDVNLPKKLCN
                     SEFCGENLSKQKFTRAVKKLNANILYLCFSQHVNLDQLQPLHTLRNLMYLVSPSSEHL
                     GRSGPFEVRADLEESMEFVDPGVAGESDESGDERVSDEETDLGTDWENLPSPRFCDIP
                     SQSVEVSQSQSTQASPPIASSSAGGMISSAAASVTSWFKAYTGHR"
ORIGIN      
        1 gtagaactgt ttcctaaaga aaactgctcc ttgatgatgg ctctccctgt cagaatttcg
       61 tgcactctag atggaaaata atgtcctgca agatgaggat tgaacagtta aaacaaacaa
      121 tatgtaaagg aaatgaagaa atggagaaaa attctgaagg ccttctcaaa accaaggaaa
      181 agaatcagaa gctttacagt cgagcacaac ggcaccaaga gaaaaaggag aagattcaga
      241 ggcataatcg caaacttggt gacctggtag aaaaaaagac cattgactta agaagtcatt
      301 atgagcgtct ggcaaatctt cgacgatccc atatattaga gctcacctct gtcatttttc
      361 caatcgagga agtaaagacg ggtgtgagag accccgcaga tgtgtcttca gagagtgaca
      421 gtgccatgac ctccagcact gtgagcaagc ttgctgaagc ccggaggaca acttacctct
      481 caggacgatg ggtctgtgac gatcacaacg gagacaccag cattagcatt acagggcctt
      541 ggattagcct ccctaacaat ggggactact ctgcctacta cagctgggtg gaggagaaga
      601 aaacaaccca ggggcctgac atggagcaga gtaaccctgc ctacaccatc agtgctgcgc
      661 tgtgctatgc aactcagctg gtcaacattc tgtctcatat acttgatgta aatcttccca
      721 aaaagctctg caacagtgaa ttttgtggcg aaaatctaag caagcagaaa tttactcgag
      781 cagtgaagaa actgaatgca aatattcttt acctttgttt ttctcagcat gtaaatttag
      841 atcaattaca accactgcat accctcagga atctaatgta cctggtcagt ccaagctctg
      901 aacacctagg caggtcaggg ccctttgaag tacgagcaga ccttgaggag tccatggaat
      961 ttgtggatcc cggagttgct ggagaatcag atgagagcgg agatgagcgc gtcagcgatg
     1021 aagaaaccga cctgggcaca gactgggaga acttgcctag tccccggttt tgtgatatcc
     1081 cttcccagtc tgtggaagtc tcccagagtc agagcaccca ggcgtcccca cccatcgcga
     1141 gcagcagtgc aggtgggatg atctcctctg cagcagcctc ggtgacctcc tggtttaaag
     1201 cttacactgg acaccgttaa cgagcatgga ccaaaacata ccaaatctgc atcaagaaag
     1261 ttcttctccc actacactct agtaaacatt ttctgtttaa gttaagatag tgtctggaac
     1321 aaagaggtta aagtgttgtt ttgttttgtc tttttaagca gggagacaaa catttctatt
     1381 tgccaagtgg cctgtgatgg tgaccaacat gcttatgata attaagagaa caggggtcga
     1441 aggtctttct acccagacca gtgctggtgg aaggaggacc tgtgcgtgtg gccagttctg
     1501 ccaaggaagc agttgatttg ggttccctct gggcccgggc caccgggccc acagatatgg
     1561 gtcagtgtgc tggtccttgc ggtgctgaga ctgttcctga cactttaagt tttagaggtt
     1621 ggttgaatca caagaggtga ttcttgatta ttaggacatg aaagataaaa gctctttaat
     1681 aagagttttt ctgccattgt tttttgtatg agaaccagca ggcaatttaa aatttctaat
     1741 ttggtccttt gattttgttt gggaggggtg agttacacgt attttattca tgctgctctg
     1801 tcgtagtttg tcagacattc ctgtttttct ttcccccaca caccaaagaa aatgaaagtc
     1861 tttttcttta ggacccacat ccataaatgg aagaaatcct ggctgcaata atgtctagag
     1921 agtttttaac tattttcttg tattctgagg ggaattaagc ttattcttac ctagttgaat
     1981 tcctgccatc cacactatga gcattttgaa attgaactta tattttctgg gtgaaaataa
     2041 gtcatgaagg tcattccctt atgtaagctc aatgcctgcc tgggcacagg ggaaaagcca
     2101 cttagttaag tggcctctgg tcattcttgt ggtgtccact ttctttctat gggattgagt
     2161 aggtggcagg tgttttcagg ggaaaccatc ctacttgttt ccccgaactc tttgttgctc
     2221 tgaggacaca gctttgctca gaaatgcagc gcagatcctt acggctgatg ctactctgct
     2281 ctgttctggg gaaagcacaa tataaagaaa gaatttccca gccaggcgca gtggctcacg
     2341 cctgtaatcc cagcacttta ggaggccgag gcaggcggat cacttgaggt caggagtttg
     2401 agagcagcct ggctaacatg gtgaaaccct gtttctacta aaaatacaaa aaattaccgg
     2461 gtgtggtggc gcacgcctgt aatcccagct actcgggagg ctgcggcagg agaatcgctt
     2521 gaaccgggag gcagaggttg cagtgagccg agattgtgcc attgcactcc agcctgggca
     2581 acaagagcga aactccgtct caaaaaaaaa aagaatttcc ctcagcagga gatcattttc
     2641 agctcacgtg tcttgtcatt cttttagtga caatcttaca agaaaactat aatgagagag
     2701 gcattatgta caaatatgta agtagtttat ttttaataac tgcaaaaaaa tcctatgtaa
     2761 caactaccaa aagaaatcct atgaaagagt cctaacaggc attattacca tatcttatgt
     2821 gattggcatg atagcacctc tgataaatca ttcagaggtt tgccatgccc cagcttcttt
     2881 tctcatcata ataattgtag ttgatacttt gcctccaagt ccgaggtgct atatagcttt
     2941 tgctaatggt atatttggtg ttttgtatag ttttgggtag agttgcagaa cggagtttat
     3001 ttctatccgg tagtcacaaa ttccttggct ctatgaattt tccatgaaag gaggaagtag
     3061 gcttttctcg ttgtgggtgg tctttttttt ttttggagac ggagtctcac tcagctgccc
     3121 aggctggagt gtagtggcac catctccgct cactgcaacc accatctcct gggttcaagc
     3181 aattcttcca tctcaacctc ccgagtagct gggattatag gcacctgcca tcatgcccag
     3241 ctaatttttg tattttagta aagacggggg ttttcaccat gttggccagg ctggtcttga
     3301 actcctgact tcaggtgatc cgcttgcctt ggcctcctaa agtgctagga ttacaggcct
     3361 gagccaccgc gcccggcccc ttatgggttc ttctacactg ctgggatctc tgttttaagt
     3421 gctcagcttc atgattgatt gctgggcttc cattttccca tccagttctg gagttcgtag
     3481 agagtgaaga tggtagactt gaacagataa ataaacttaa cgatcttgta agagttgtct
     3541 agctacttaa aaccctcaga agtaagagct tagtctcacg agttgtaaga gtgggatttg
     3601 gagcttggtg gtggagactg acttcagctg agagatgcac aacagtcatg gttttcttaa
     3661 gcctcttatg aaaccatgaa tgagagatga agctaaagaa tagaatccag agatcacaaa
     3721 ctcatctaga gtacttccac aaaatttaca aagatgtggg aactttatgg ataggatata
     3781 ttttgtttgt tgttgttaat atcaactaga ggcactttac atagggttaa gtgatcgaac
     3841 ccttttgtgg ttttgaacac caacatactg gcttacactg ctgaaatatt ttgggtttca
     3901 ttattttgca ctggatccac cctgtaaata ctcttaagta tacatttcaa ccactgtttt
     3961 ttctactctt tttgctgctc attaaaatct ttcatgtagg tgccagaacc atatgtaaac
     4021 agctttttaa aaaattgaag ctggtatttt gtttaaacaa aaagccatag aacttggtca
     4081 tgttttccat tttaaaatga tttactgaaa caaagtaata ctaataaaaa cccacaggca
     4141 ccaaacaggc tgcttaaaat ggtctgttaa agacattttt tggttatgga atataagaaa
     4201 agttttgcac atctgtaagg gggaaaaaca gtatatcacc attgggtaga gtggacggga
     4261 ctcatgtaag gactcaattt ggggaagagc attcagtggc atgctgttag aggactagtg
     4321 tccgagaatc tcctcacagt atcatgttgc aggaattccc cattgctctg caacttccaa
     4381 accagtttga gtcatacaaa tgttttctaa acttttattg tattactgca ataaatcttt
     4441 taacagta
//
