LOCUS       NM_017552               8112 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens ATPase family AAA domain containing 2B (ATAD2B),
            transcript variant 1, mRNA.
ACCESSION   NM_017552 XM_039676 XM_938907
VERSION     NM_017552.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8112)
  AUTHORS   Lloyd,J.T., McLaughlin,K., Lubula,M.Y., Gay,J.C., Dest,A., Gao,C.,
            Phillips,M., Tonelli,M., Cornilescu,G., Marunde,M.R., Evans,C.M.,
            Boyson,S.P., Carlson,S., Keogh,M.C., Markley,J.L., Frietze,S. and
            Glass,K.C.
  TITLE     Structural Insights into the Recognition of Mono- and Diacetylated
            Histones by the ATAD2B Bromodomain
  JOURNAL   J Med Chem 63 (21), 12799-12813 (2020)
   PUBMED   33084328
REFERENCE   2  (bases 1 to 8112)
  AUTHORS   Lloyd,J.T. and Glass,K.C.
  TITLE     Biological function and histone recognition of family IV
            bromodomain-containing proteins
  JOURNAL   J Cell Physiol 233 (3), 1877-1886 (2018)
   PUBMED   28500727
  REMARK    Review article
REFERENCE   3  (bases 1 to 8112)
  AUTHORS   Gong,F., Chiu,L.Y., Cox,B., Aymard,F., Clouaire,T., Leung,J.W.,
            Cammarata,M., Perez,M., Agarwal,P., Brodbelt,J.S., Legube,G. and
            Miller,K.M.
  TITLE     Screen identifies bromodomain protein ZMYND8 in chromatin
            recognition of transcription-associated DNA damage that promotes
            homologous recombination
  JOURNAL   Genes Dev 29 (2), 197-211 (2015)
   PUBMED   25593309
REFERENCE   4  (bases 1 to 8112)
  AUTHORS   Alabert,C., Bukowski-Wills,J.C., Lee,S.B., Kustatscher,G.,
            Nakamura,K., de Lima Alves,F., Menard,P., Mejlvang,J.,
            Rappsilber,J. and Groth,A.
  TITLE     Nascent chromatin capture proteomics determines chromatin dynamics
            during DNA replication and identifies unknown fork components
  JOURNAL   Nat Cell Biol 16 (3), 281-293 (2014)
   PUBMED   24561620
REFERENCE   5  (bases 1 to 8112)
  AUTHORS   Filippakopoulos,P., Picaud,S., Mangos,M., Keates,T., Lambert,J.P.,
            Barsyte-Lovejoy,D., Felletar,I., Volkmer,R., Muller,S., Pawson,T.,
            Gingras,A.C., Arrowsmith,C.H. and Knapp,S.
  TITLE     Histone recognition and large-scale structural analysis of the
            human bromodomain family
  JOURNAL   Cell 149 (1), 214-231 (2012)
   PUBMED   22464331
REFERENCE   6  (bases 1 to 8112)
  AUTHORS   Mitra,P.S., Ghosh,S., Zang,S., Sonneborn,D., Hertz-Picciotto,I.,
            Trnovec,T., Palkovicova,L., Sovcikova,E., Ghimbovschi,S.,
            Hoffman,E.P. and Dutta,S.K.
  TITLE     Analysis of the toxicogenomic effects of exposure to persistent
            organic pollutants (POPs) in Slovakian girls: correlations between
            gene expression and disease risk
  JOURNAL   Environ Int 39 (1), 188-199 (2012)
   PUBMED   22208759
REFERENCE   7  (bases 1 to 8112)
  AUTHORS   Leachman,N.T., Brellier,F., Ferralli,J., Chiquet-Ehrismann,R. and
            Tucker,R.P.
  TITLE     ATAD2B is a phylogenetically conserved nuclear protein expressed
            during neuronal differentiation and tumorigenesis
  JOURNAL   Dev Growth Differ 52 (9), 747-755 (2010)
   PUBMED   21158754
  REMARK    GeneRIF: The ATAD2B may play a role in neuronal differentiation and
            tumor progression.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC066692.3, AK094821.1,
            BC171846.1, AB033066.1, AK125718.1 and BM974506.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_017552.3.
            
            Summary: The protein encoded by this gene belongs to the AAA ATPase
            family. This family member includes an N-terminal bromodomain. It
            has been found to be localized to the nucleus, partly to
            replication sites, consistent with a chromatin-related function.
            Alternative splicing of this gene results in multiple transcript
            variants. [provided by RefSeq, Jul 2014].
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1966682
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000238789.10/ ENSP00000238789.5
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-9                 AC066692.3         93173-93181         c
            10-1223             AK094821.1         1-1214
            1224-2511           BC171846.1         1162-2449
            2512-3311           AB033066.1         1-800
            3312-4973           AK125718.1         2104-3765
            4974-8105           AB033066.1         2448-5579
            8106-8112           BM974506.1         12-18               c
FEATURES             Location/Qualifiers
     source          1..8112
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p24.1-p23.3"
     gene            1..8112
                     /gene="ATAD2B"
                     /note="ATPase family AAA domain containing 2B"
                     /db_xref="GeneID:54454"
                     /db_xref="HGNC:HGNC:29230"
                     /db_xref="MIM:615347"
     exon            1..569
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     CDS             354..4730
                     /gene="ATAD2B"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="ATPase family AAA domain-containing protein 2B
                     isoform 1"
                     /protein_id="NP_060022.2"
                     /db_xref="CCDS:CCDS46227.1"
                     /db_xref="GeneID:54454"
                     /db_xref="HGNC:HGNC:29230"
                     /db_xref="MIM:615347"
                     /translation="MVNTRKSSLRLLGSKSPGPGPGPGAGAEPGATGGSSHFISSRTR
                     SSKTRAASCPAAKAGGSGGAGVTLDEARKVEVDGSLSDSHVSPPAKRTLKQPDSVCKD
                     KSKSRSTGQREEWNLSTGQARLTSQPGATLPNGHSGLSLRSHPLRGEKKGDGDLSCIN
                     GDMEVRKSCRSRKNRFESVNQSLLFDQLVNSTAEAVLQEMDNINIRRNRRSGEVERLR
                     MWTDTEFENMDMYSRVKRRRKSLRRNSYGIQNHHEVSTEGEEEESQEEDGDIEVEEAE
                     GEENDRPYNLRQRKTVDRYQAPPIVPAHQKKRENTLFDIHRSPARRSHIRRKKHAIHS
                     SDTTSSDEERFERRKSKSMARARNRCLPMNFRAEDLASGILRERVKVGASLADVDPMN
                     IDKSVRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLV
                     ARALANECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEID
                     GLAPVRSSRQDQIHSSIVSTLLALMDGLDNRGEIVVIGATNRLDSIDPALRRPGRFDR
                     EFLFNLPDQKARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALIA
                     LRRRYPQIYASSHKLQLDVSSIVLSAQDFYHAMQNIVPASQRAVMSSGHALSPIIRPL
                     LERSFNNILAVLQKVFPHAEISQSDKKEDIETLILEDSEDENALSIFETNCHSGSPKK
                     QSSSAAIHKPYLHFTMSPYHQPTSYRPRLLLSGERGSGQTSHLAPALLHTLERFSVHR
                     LDLPALYSVSAKTPEESCAQIFREARRTVPSIVYMPHIGDWWEAVSETVRATFLTLLQ
                     DIPSFSPIFLLSTSETMYSELPEEVKCIFRIQYEEVLYIQRPIEEDRRKFFQELILNQ
                     ASMAPPRRKHAALCAMEVLPLALPSPPRQLSESEKSRMEDQEENTLRELRLFLRDVTK
                     RLATDKRFNIFSKPVDIEEVSDYLEVIKEPMDLSTVITKIDKHNYLTAKDFLKDIDLI
                     CSNALEYNPDKDPGDKIIRHRACTLKDTAHAIIAAELDPEFNKLCEEIKEARIKRGLS
                     VTSEQINPHSTGARKTETRVEEAFRHKQRNPMDVWHNSANKCAFRVRRKSRRRSQWGK
                     GIIKKRKVNNLKKDEEDTKFADYENHTEDRKLLENGEFEVSTDCHEENGEETGDLSMT
                     NDESSCDIMDLDQGQRLNNGAGTKENFASTEEESSNESLLVNSSSSLNPEQTSRKETF
                     LKGNCLNGEASTDSFEGIPVLECQNGKLEVVSFCDSGDKCSSEQKILLEDQSKEKPET
                     STENHGDDLEKLEALECSNNEKLEPGSDVEVKDAELDKEGASKVKKYRKLILEQAKTT
                     SLELVPEEPSEPVPPLIVDRERLKKLLDLLVDKSNNLAVDQLERLYSLLSQCIYRHRK
                     DYDKSQLVEEMERTVHMFETFL"
     exon            570..721
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            722..771
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            772..925
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            926..1028
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1137
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1138..1254
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1255..1330
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1429
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..1541
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1542..1657
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1658..1832
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1833..1921
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1922..2081
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2082..2172
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2173..2484
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2485..2620
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2621..2807
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2808..2993
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2994..3129
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            3130..3326
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            3327..3486
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            3487..3609
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            3610..3747
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            3748..4431
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            4432..4559
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            4560..4688
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     exon            4689..8112
                     /gene="ATAD2B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8091..8096
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ATAD2B"
                     /note="hexamer: AATAAA"
     polyA_site      8112
                     /gene="ATAD2B"
                     /note="major polyA site"
ORIGIN      
        1 ctcgttggcc ctgcggcgct ggagccttga cgcacggagc tcgagagcga gaacgggaga
       61 gaaaggggta gaaatggcgg ctccgctcgg ctcccgctga ggagggcgaa gccggcggag
      121 tgtctgtgct gccggtctgc agcaccgccc ccgcttcccg cacgccgcct gctcacgccg
      181 acttcccttc ctctgcccgg ctctctcttg tgctcgtctg cgctccgcac gctccgggcc
      241 ggctcgtctc tcattgcccg gctcggctcc gctggccctg actgaccggc cggcgggccg
      301 gccttgctcg gctctcccgg gcgcggcgtg gactccgtcc ccctggctgg accatggtga
      361 acacccggaa gagctctctc cgccttctcg ggtccaagtc tcctggtccc gggcctgggc
      421 ctggggccgg agcagagcct ggggcgaccg gaggcagcag ccatttcatc tcctctcgga
      481 cccgctcctc caagacccgc gccgccagct gccccgccgc caaagccggg ggaagcggtg
      541 gcgccggcgt cactctggat gaggccagga aagttgaagt tgatggtagt ttaagtgata
      601 gccacgtatc tcctccagcc aaacgcactt tgaaacaacc tgattctgtt tgcaaagaca
      661 aatcaaaatc acgaagtact ggtcagcgag aggaatggaa cttatcaact ggacaggcca
      721 ggttaacttc tcagcctggt gctacattac caaatggaca tagtggctta tcccttcgaa
      781 gccatcccct tcgaggggaa aagaagggag atggggacct ttcttgtata aatggtgaca
      841 tggaagtcag aaaaagttgt cgttccagga aaaacagatt tgaaagtgtg aaccagagtt
      901 tgttatttga tcaactagta aatagcactg ctgaagctgt actacaggaa atggacaaca
      961 ttaacatccg acggaatcgt cgatcaggag aagtagaacg acttcgaatg tggacagata
     1021 cagaatttga aaacatggat atgtattcaa gagtgaaaag gcgaagaaag tcactaagaa
     1081 gaaatagtta tgggatacaa aatcatcatg aagtttctac tgagggtgaa gaagaagaat
     1141 ctcaagagga ggatggagat atagaagttg aagaggcaga aggagaagaa aatgatagac
     1201 catataattt gagacagaga aaaacagtgg atcgatacca agcacctcca atagtaccag
     1261 ctcatcaaaa aaagagggaa aacacgctgt ttgatattca tagatctcca gcaagaagaa
     1321 gccatattag gagaaagaag catgccattc atagtagtga cacaacttct tctgatgagg
     1381 aacgctttga aagaaggaaa tcaaagagca tggcaagagc aagaaataga tgtttgccta
     1441 tgaacttcag agcagaggac ttagctagcg gtattctccg agaacgagtg aaagtgggtg
     1501 caagcttggc tgatgttgat ccaatgaaca ttgataaatc agtacggttt gatagcatag
     1561 gtggattgag ccatcatatt catgcgctaa aggaaatggt agtattccca cttttatatc
     1621 cagaaatttt tgaaaagttt aaaattcagc ctccaagggg ctgtttgttt tatggccctc
     1681 ctggcacagg taaaaccttg gttgccagag cattagctaa tgaatgcagc caaggagaca
     1741 aaaaagtggc tttttttatg cgaaaaggag cagattgttt gagcaagtgg gttggtgaat
     1801 ctgaaaggca acttaggctt ctttttgatc aggcatattt gatgagacct tctataatat
     1861 tttttgatga aatagatgga ttagctccag ttcgctctag cagacaagat cagatccaca
     1921 gctctatagt atcaaccctc cttgctctta tggatggatt agataatagg ggtgaaattg
     1981 ttgttattgg tgctacaaac agacttgact ctatagatcc tgcactcagg agacctggtc
     2041 gttttgacag agaattcctc ttcaacctgc ctgatcaaaa ggcaagaaaa cacatcttac
     2101 agatccatac cagggactgg aatccaaaat tgtcagatgc atttttaggt gaattggctg
     2161 aaaaatgtgt tggctactgt ggagccgata tcaaggccct gtgcactgaa gccgccctga
     2221 ttgcactgcg gaggcgttat ccccagatct atgctagcag tcataaactg cagctggatg
     2281 tttcctcaat agtgcttagt gcccaagatt tttaccatgc aatgcagaat atcgtgcctg
     2341 cttcccaacg tgctgtgatg tcttcagggc atgcactatc ccccatcata agaccactgc
     2401 tggaaagaag cttcaacaac atcctagcag tcttgcaaaa agtgtttcct catgctgaaa
     2461 ttagccagag tgacaaaaaa gaagatatag aaactttaat tttagaggat agtgaagatg
     2521 aaaatgcttt atcaattttt gagaccaatt gtcactcagg atcaccaaag aaacagtcat
     2581 catctgctgc tatacataaa ccctaccttc attttacaat gtcaccatat catcagccaa
     2641 cctcttacag gccacgctta ttgctctctg gagaacgggg ctcaggtcaa acttctcacc
     2701 ttgctccagc acttttgcac actctagaaa gattctctgt gcatagacta gatctcccag
     2761 cactttattc agttagtgcc aaaacacctg aggaatcatg tgcacagatt tttcgtgaag
     2821 ctcgaagaac agtacctagt attgtttaca tgcctcacat tggggattgg tgggaagctg
     2881 tcagtgaaac tgtgagagca acttttctga cattgctaca agatatacca tcattttcac
     2941 ctatattttt attgtctacc tctgaaacca tgtacagtga actgcctgaa gaggttaaat
     3001 gtatctttag aatacagtat gaagaggtct tgtatattca aaggcctatt gaagaagaca
     3061 gaagaaaatt ttttcaagaa ttgattctca atcaggcatc aatggctcca ccacgaagga
     3121 aacatgctgc tctttgtgct atggaagtgc ttcctcttgc actaccttct ccacctcgtc
     3181 aattatcaga atcagaaaaa agtcgaatgg aggaccagga ggaaaatact ttaagagagt
     3241 tgcggttgtt tctcagggat gtaaccaaga ggctggccac agataaacgc tttaacatct
     3301 tcagcaaacc ggtggatatt gaagaggttt cagattatct tgaagtaatc aaggaaccaa
     3361 tggacttatc aacagtaata actaaaattg ataaacataa ttacctgact gcaaaggatt
     3421 tcctgaaaga tattgacctc atctgtagca atgctttaga gtataatcca gataaggacc
     3481 caggagataa aataattagg cacagggctt gtaccctgaa ggacactgca catgctatca
     3541 ttgcagctga attagatcca gaatttaata aactttgtga ggaaattaag gaagcaagaa
     3601 taaaaagagg cttatcagta acatcagaac aaataaatcc tcatagtact ggagctcgga
     3661 agacagaaac tagagtcgaa gaggcatttc ggcacaaaca aagaaatcca atggatgtgt
     3721 ggcacaactc tgcaaataaa tgtgcatttc gggttcggag aaaatcaagg cggagatcac
     3781 agtggggtaa aggaattatt aagaaaagga aagttaataa tttaaaaaaa gatgaagaag
     3841 acaccaaatt tgcagactat gagaaccata cggaggacag gaaattatta gagaatggag
     3901 agtttgaggt aagcactgac tgccatgagg aaaatggaga agagactgga gacttatcta
     3961 tgaccaatga tgaatcatcc tgtgacatca tggacttgga ccaggggcag aggcttaaca
     4021 atggagcagg cacaaaagag aactttgcat ctactgagga ggaaagttca aatgaatctc
     4081 tactggtcaa cagcagcagt tccttaaacc cggagcagac ctccaggaaa gagactttcc
     4141 ttaaaggaaa ttgtctaaat ggtgaggctt ccactgacag ttttgaagga ataccagttc
     4201 tggaatgtca gaatggcaag cttgaagtag tttctttctg tgatagtgga gataaatgta
     4261 gttctgaaca aaagattctt ctggaggacc agtcaaaaga aaaaccagaa acttcgactg
     4321 aaaatcatgg agatgatctt gagaaactag aggcactgga atgtagcaat aatgagaagt
     4381 tagaacctgg ctctgatgtg gaggttaaag atgcagaact ggataaagaa ggtgcttcta
     4441 aagtaaagaa ataccgtaaa ttaattttag agcaggcaaa aacgacaagc ctggaactgg
     4501 ttccagaaga gccatctgag cctgtgcctc ctcttatagt tgatcgtgag agattgaaga
     4561 aattgcttga tttgttggtg gataaaagca acaatctggc agttgatcag cttgagagat
     4621 tatattctct tcttagtcag tgtatctacc gtcatcgtaa agattatgac aaatcacaac
     4681 ttgtagagga gatggaaaga acagttcata tgtttgagac attcctatga acttttcaag
     4741 atgagtggtt tatcctctcc aatctgctcc tcacagagca gtcttctgag ccattcaatt
     4801 tcaaattgca ccaattatgt gcagagcctt ggtgtaaagt gctctctcac tcattctttc
     4861 tctctgttga atttggtgct attgtctcag gtacctgaaa ccaaccagcc tacaagaacc
     4921 aaacagaact tcagaaacat gttgtatttt ccacaaataa aaaatacaac cccacagctt
     4981 ggagattttg gtgctacaga aactgctctc gcttctgctc ctctttttgt gcactctctt
     5041 ttggagactc ctctcttagg gagcagacca gcaaacagga ggaaactgga tgggggcagt
     5101 tctaactgtg ttgaattgtt taaacagtgg gcaacttgtt attttttttt cctccatttt
     5161 acccctttaa tcatattttt cccccatctg ggtaatggac tgaaacctgt tttagagttg
     5221 gctatggtct gttctggtgg gaagctgaag aaactggatg aaattaggtc aggctcttta
     5281 gaactgcctt taacgtgcct ttttattcat ttgaggaaga taaggctaaa aggatgggct
     5341 gtttgaagca aataaattag aaatatttct ttggtcacaa ccttgaaaat aagttttgat
     5401 actctatgtc attaagagac aaccagtgtt tgggtatgaa atgcctgtct tattctcaaa
     5461 gctcaatcaa gacacccagt aagccacata atatactaaa atggtaagtt ttcttgtaag
     5521 gtctgttttg gtttaagaaa catgaataac aacaaagaat aatacacagt ccacacacaa
     5581 aaaaacaaaa aacaaaactg cacacgtttt ggtattgcca acaatgatga ctagaaaata
     5641 aatagatagt ggccattttt tcttctgtca gtggcaattt aatagttatt catgtttgag
     5701 ttcccagaga aaaatggttt tcatatgtag taaattgttg ttttgtttta aagccaggac
     5761 ttgccaaatg gacagaaaag agaggaattc atcagaagct ccataaaatt cattttctgt
     5821 atgcttaatt gcaaacgagc tctggtatgg tccttgaata acagtattaa tgtttaaatc
     5881 ccatctccta agcttacctt cacaactctt ctttttgatt ggaaaccatt ttgaatcttg
     5941 ttgagtgatt tctgtgaatt gtatgtatct gaaattaatt atgggttact agttttacaa
     6001 aaactttcta caaatttgga gacacagtct aggcagttgc aatgaggcaa aggatgcagt
     6061 gacttttttt atcagatgat ttttaaacaa aaagaaaatt ttgccagcaa gttggcttgg
     6121 tatcttcatt cattgtagcc gttagctgca ggtgtgtctt tccaatatat gcaacacatg
     6181 tagtttgggt tttaattagg gcgaatggtc ttggactact gcagagattc tgagctacct
     6241 cagctttttg tattttagtt accaacagtg tttacagagt cttgtaatca ctttgccacc
     6301 gtttacatcc tgaagctaag gtacttgtct ccttgtcttt ggctctttgt agtgtgcaga
     6361 aagcatactt tggccatagc ctactgcagt aatccaaagt gcttctttgc atttacattt
     6421 acatctaacg ccttctaatt ctagcttaat ttttttttaa atgccacgtg ttttctttgt
     6481 acctagtctg tgaagtttct gtaatatcca gttagtcata caagtcaaga tgctacccat
     6541 gtagacacac tgtattttta aggtgggcaa gtgcgattaa cgatgaacca ttttaaaggg
     6601 gaggttattt gaaacctcta atttgattat tgggaggatt ttcatgcttt ctttagtatt
     6661 tattaccatc ataccgattc aaactatttt attgtctaat acattagcat tttgtatttt
     6721 gatggaaatt gttacagaat ttaaagattt gatgaaataa gatgtagcag attttttgta
     6781 gcaagtttct ggtaaaaggg ttttttgcaa gtctcaggtt cttgctgcac tatttttttt
     6841 taaatattta ttccagttat tctaattcag aagcattctt ttcaagtaac agcagcactt
     6901 gtgaaaggaa aaaaaaatgc acatgtttct tagtaggtta ctaaatttgt acaattaatt
     6961 aagattttag ccatcagtga gtttgaaaag ggaaatgtat ttattttcag cattaaaatg
     7021 cttccaaaag atcaagttgc ttttgtttgt ttgttttttt aaccgtaatg tagatggaga
     7081 aattggaggc aacctcagta taggaactgc cactttgaac agtttaggtc ttaaagagaa
     7141 agtcaatcta atgccaaggg gagaacaatg agctgaaatt gtaccaactc ctctggccct
     7201 ccttccctca attaaaaaaa cacacttacc agttttgctt attttacaga tatctggtgg
     7261 ttctatagtt taaagcagct tgtgaaatta aaaaagtgga ctcaattttg tttacctttc
     7321 tgtaagtttt tcatttttgc tgtatagcat tggcaaaaat atgtacaaat tgacctctgt
     7381 tcttatttcc tattgtgagc attataaaga taagctccta tgtaaaacct tgctctcaga
     7441 tgagtaaaat atgtatcaca gcatagctca gcaataattc atgctcagct gtggggaccc
     7501 tgggggcttt ttgaagatga tggaaccgca ctagggttga aactgatggc tgtggagtta
     7561 attgtgtttt cgagcttgaa tctcacctgt gatttttttt ttttaatgtt gtttcatgac
     7621 ttgatttttc tcataagcca atgtatttgt aggtttactg gattttattt ttagggagtg
     7681 ggtaatttct tccctttttt gattaagttg gttcagctat ggtgctattc agtaggtatc
     7741 ttcagtgtca ggtcccgtag ctgaatgcca ttgttattat aattattatt tgtaatcaca
     7801 ttgtaagctt gaatttgggc ttgtacctgc atcttttgta ttctgtacat ctggttactt
     7861 agactttggg agtccaattt ggtttcagtc atgtatgtct actttgtagt ttaagtagac
     7921 ttcatcaact atggtctatt ttgggtttgt agttttaatt tagaattgtg ttaaattgat
     7981 gttttgcatt tgacttcatt tgacattagt tgaagtaaat tatttaattt ttgaattctg
     8041 gaatttgaac atttactgta atttgtaata taactgctgt gaaatacttg aataaagatg
     8101 acaagaaaaa ca
//
