LOCUS       NM_001321967            4334 bp    mRNA    linear   PRI 15-OCT-2024
DEFINITION  Homo sapiens ATPase family AAA domain containing 1 (ATAD1),
            transcript variant 2, mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001321967 XM_005270251
VERSION     NM_001321967.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4334)
  AUTHORS   Kim,J., Goldstein,M., Zecchel,L., Ghorayeb,R., Maxwell,C.A. and
            Weidberg,H.
  TITLE     ATAD1 prevents clogging of TOM and damage caused by un-imported
            mitochondrial proteins
  JOURNAL   Cell Rep 43 (8), 114473 (2024)
   PUBMED   39024102
  REMARK    GeneRIF: ATAD1 prevents clogging of TOM and damage caused by
            un-imported mitochondrial proteins.
REFERENCE   2  (bases 1 to 4334)
  AUTHORS   Zhou,Q., Yang,Y., Xu,Z., Deng,K., Zhang,Z., Hao,J., Li,N., Wang,Y.,
            Wang,Z., Chen,H., Yang,Y., Xiao,F., Zhang,X., Gao,S. and Li,Y.P.
  TITLE     ATAD1 inhibits hepatitis C virus infection by removing the viral
            TA-protein NS5B from mitochondria
  JOURNAL   EMBO Rep 24 (11), e56614 (2023)
   PUBMED   37789674
  REMARK    GeneRIF: ATAD1 inhibits hepatitis C virus infection by removing the
            viral TA-protein NS5B from mitochondria.
REFERENCE   3  (bases 1 to 4334)
  AUTHORS   Craddock,K.E., McKee,J.L., Fitzgerald,M., Ahrens-Nicklas,R. and
            Agarwal,S.
  TITLE     Neonatal Hypertonia and Progressive Respiratory Failure due to
            Novel Heterozygous Mutation in ATAD1
  JOURNAL   Pediatr Neurol 142, 56-57 (2023)
   PUBMED   36933275
  REMARK    GeneRIF: Neonatal Hypertonia and Progressive Respiratory Failure
            due to Novel Heterozygous Mutation in ATAD1.
REFERENCE   4  (bases 1 to 4334)
  AUTHORS   Winter,J.M., Fresenius,H.L., Cunningham,C.N., Wei,P., Keys,H.R.,
            Berg,J., Bott,A., Yadav,T., Ryan,J., Sirohi,D., Tripp,S.R.,
            Barta,P., Agarwal,N., Letai,A., Sabatini,D.M., Wohlever,M.L. and
            Rutter,J.
  TITLE     Collateral deletion of the mitochondrial AAA+ ATPase ATAD1
            sensitizes cancer cells to proteasome dysfunction
  JOURNAL   Elife 11, e82860 (2022)
   PUBMED   36409067
  REMARK    GeneRIF: Collateral deletion of the mitochondrial AAA+ ATPase ATAD1
            sensitizes cancer cells to proteasome dysfunction.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4334)
  AUTHORS   Cao,L., Dong,G. and Li,H.
  TITLE     CircRNA circ-ATAD1 suppresses miR-618 maturation to participate in
            colorectal cancer
  JOURNAL   BMC Gastroenterol 22 (1), 215 (2022)
   PUBMED   35505304
  REMARK    GeneRIF: CircRNA circ-ATAD1 suppresses miR-618 maturation to
            participate in colorectal cancer.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4334)
  AUTHORS   Hendrickson,S.L., Lautenberger,J.A., Chinn,L.W., Malasky,M.,
            Sezgin,E., Kingsley,L.A., Goedert,J.J., Kirk,G.D., Gomperts,E.D.,
            Buchbinder,S.P., Troyer,J.L. and O'Brien,S.J.
  TITLE     Genetic variants in nuclear-encoded mitochondrial genes influence
            AIDS progression
  JOURNAL   PLoS One 5 (9), e12862 (2010)
   PUBMED   20877624
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
            Publication Status: Online-Only
REFERENCE   7  (bases 1 to 4334)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   8  (bases 1 to 4334)
  AUTHORS   Vasilescu,J., Zweitzig,D.R., Denis,N.J., Smith,J.C., Ethier,M.,
            Haines,D.S. and Figeys,D.
  TITLE     The proteomic reactor facilitates the analysis of affinity-purified
            proteins by mass spectrometry: application for identifying
            ubiquitinated proteins in human cells
  JOURNAL   J Proteome Res 6 (1), 298-305 (2007)
   PUBMED   17203973
REFERENCE   9  (bases 1 to 4334)
  AUTHORS   Grupe,A., Li,Y., Rowland,C., Nowotny,P., Hinrichs,A.L., Smemo,S.,
            Kauwe,J.S., Maxwell,T.J., Cherny,S., Doil,L., Tacey,K., van
            Luchene,R., Myers,A., Wavrant-De Vrieze,F., Kaleem,M.,
            Hollingworth,P., Jehu,L., Foy,C., Archer,N., Hamilton,G.,
            Holmans,P., Morris,C.M., Catanese,J., Sninsky,J., White,T.J.,
            Powell,J., Hardy,J., O'Donovan,M., Lovestone,S., Jones,L.,
            Morris,J.C., Thal,L., Owen,M., Williams,J. and Goate,A.
  TITLE     A scan of chromosome 10 identifies a novel locus showing strong
            association with late-onset Alzheimer disease
  JOURNAL   Am J Hum Genet 78 (1), 78-88 (2006)
   PUBMED   16385451
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   10 (bases 1 to 4334)
  AUTHORS   Deloukas,P., Earthrowl,M.E., Grafham,D.V., Rubenfield,M.,
            French,L., Steward,C.A., Sims,S.K., Jones,M.C., Searle,S.,
            Scott,C., Howe,K., Hunt,S.E., Andrews,T.D., Gilbert,J.G.,
            Swarbreck,D., Ashurst,J.L., Taylor,A., Battles,J., Bird,C.P.,
            Ainscough,R., Almeida,J.P., Ashwell,R.I., Ambrose,K.D.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Bates,K.,
            Beasley,H., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.C.,
            Burrill,W., Burton,J., Cahill,P., Camire,D., Carter,N.P.,
            Chapman,J.C., Clark,S.Y., Clarke,G., Clee,C.M., Clegg,S., Corby,N.,
            Coulson,A., Dhami,P., Dutta,I., Dunn,M., Faulkner,L., Frankish,A.,
            Frankland,J.A., Garner,P., Garnett,J., Gribble,S., Griffiths,C.,
            Grocock,R., Gustafson,E., Hammond,S., Harley,J.L., Hart,E.,
            Heath,P.D., Ho,T.P., Hopkins,B., Horne,J., Howden,P.J., Huckle,E.,
            Hynds,C., Johnson,C., Johnson,D., Kana,A., Kay,M., Kimberley,A.M.,
            Kershaw,J.K., Kokkinaki,M., Laird,G.K., Lawlor,S., Lee,H.M.,
            Leongamornlert,D.A., Laird,G., Lloyd,C., Lloyd,D.M., Loveland,J.,
            Lovell,J., McLaren,S., McLay,K.E., McMurray,A.,
            Mashreghi-Mohammadi,M., Matthews,L., Milne,S., Nickerson,T.,
            Nguyen,M., Overton-Larty,E., Palmer,S.A., Pearce,A.V., Peck,A.I.,
            Pelan,S., Phillimore,B., Porter,K., Rice,C.M., Rogosin,A.,
            Ross,M.T., Sarafidou,T., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
            Smith,M., Standring,L., Sycamore,N., Tester,J., Thorpe,A.,
            Torcasso,W., Tracey,A., Tromans,A., Tsolas,J., Wall,M., Walsh,J.,
            Wang,H., Weinstock,K., West,A.P., Willey,D.L., Whitehead,S.L.,
            Wilming,L., Wray,P.W., Young,L., Chen,Y., Lovering,R.C.,
            Moschonas,N.K., Siebert,R., Fechtel,K., Bentley,D., Durbin,R.,
            Hubbard,T., Doucette-Stamm,L., Beck,S., Smith,D.R. and Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 10
  JOURNAL   Nature 429 (6990), 375-381 (2004)
   PUBMED   15164054
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC022016.7 and AL133327.10.
            
            On Aug 14, 2020 this sequence version replaced NM_001321967.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803617.189530.1,
                                           SRR14038196.987987.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2467148 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000680024.1/ ENSP00000506333.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-60                AC022016.7         35989-36048         c
            61-235              AC022016.7         32260-32434         c
            236-334             AC022016.7         10479-10577         c
            335-455             AC022016.7         8132-8252           c
            456-656             AC022016.7         2292-2492           c
            657-763             AL133327.10        116771-116877       c
            764-853             AL133327.10        111402-111491       c
            854-904             AL133327.10        108123-108173       c
            905-1038            AL133327.10        97239-97372         c
            1039-4334           AL133327.10        91962-95257         c
FEATURES             Location/Qualifiers
     source          1..4334
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q23.31"
     gene            1..4334
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /note="ATPase family AAA domain containing 1"
                     /db_xref="GeneID:84896"
                     /db_xref="HGNC:HGNC:25903"
                     /db_xref="MIM:614452"
     exon            1..60
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /inference="alignment:Splign:2.1.0"
     exon            61..235
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..1159
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /EC_number="3.6.1.3"
                     /note="isoform 1 is encoded by transcript variant 2;
                     ATPase family AAA domain-containing protein 1; outer
                     mitochondrial transmembrane helix translocase"
                     /codon_start=1
                     /product="outer mitochondrial transmembrane helix
                     translocase isoform 1"
                     /protein_id="NP_001308896.1"
                     /db_xref="CCDS:CCDS7386.1"
                     /db_xref="GeneID:84896"
                     /db_xref="HGNC:HGNC:25903"
                     /db_xref="MIM:614452"
                     /translation="MVHAEAFSRPLSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDPT
                     RKQKVEAQKQAEKLMKQIGVKNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITD
                     LKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPS
                     TLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMS
                     LWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKNE
                     NVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDEDEIRPVQQQ
                     DLHRAIEKMKKSKDAAFQNVLTHVCLD"
     exon            236..334
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /inference="alignment:Splign:2.1.0"
     exon            335..455
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /inference="alignment:Splign:2.1.0"
     exon            456..656
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /inference="alignment:Splign:2.1.0"
     exon            657..763
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /inference="alignment:Splign:2.1.0"
     exon            764..853
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /inference="alignment:Splign:2.1.0"
     exon            854..904
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /inference="alignment:Splign:2.1.0"
     exon            905..1038
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..4334
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1161..1166
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /note="hexamer: AGTAAA"
     polyA_site      1184
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /note="major polyA site"
     polyA_site      2475
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /note="major polyA site"
     regulatory      2710..2715
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /note="hexamer: AATAAA"
     polyA_site      2729
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /note="major polyA site"
     regulatory      3976..3981
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /note="hexamer: AATAAA"
     polyA_site      3995
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
     regulatory      4311..4316
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
                     /note="hexamer: ATTAAA"
     polyA_site      4334
                     /gene="ATAD1"
                     /gene_synonym="AFDC1; FNP001; hATAD1; HKPX4; Msp1;
                     THORASE"
ORIGIN      
        1 gcgtttcctt cctgtgtgag gccggctgag ggcacttgct cttgctgttt ctgcccctgg
       61 gttaacattc aagatggtac atgctgaagc cttttctcgt cctttgagtc ggaatgaagt
      121 tgttggttta attttccgtt tgacaatatt tggtgcagtg acatacttta ctatcaaatg
      181 gatggtagat gcaattgatc caaccagaaa gcaaaaagta gaagctcaga aacaggcaga
      241 aaaactaatg aagcaaattg gagtgaaaaa tgtgaagctc tcagaatatg aaatgagtat
      301 tgctgctcat cttgtagacc ctcttaatat gcatgttact tggagtgata tagcaggttt
      361 agatgatgtc attacggatc tgaaagacac agtcatctta cctatcaaaa agaaacattt
      421 gtttgagaat tccaggcttc tgcagcctcc aaaaggtgtt cttctctatg ggcctccagg
      481 ctgtggtaaa acgttgattg ccaaggccac agccaaagaa gcaggctgtc gatttattaa
      541 ccttcagcct tcgacactga ccgataagtg gtatggagaa tctcagaaat tggctgctgc
      601 tgtcttctcc cttgccataa agctacaacc atccatcatc tttatagatg aaatagactc
      661 ctttctacga aaccgttcaa gttctgacca tgaagctaca gccatgatga aagctcagtt
      721 tatgagtctc tgggatggat tggatactga tcacagctgc caggtcatag taatgggagc
      781 taccaatcgt cctcaggacc ttgactcggc tataatgaga agaatgccta caagatttca
      841 tatcaaccag cctgctttaa aacagagaga agcaatcctg aaactcatct tgaaaaatga
      901 aaatgtggat aggcatgtag acctgctaga agttgcccag gaaactgatg ggttttcagg
      961 aagtgaccta aaagagatgt gtcgagatgc tgccctcctc tgtgttagag aatatgttaa
     1021 ttctacatca gaagaaagcc atgacgaaga tgaaattcgg cctgttcaac agcaggacct
     1081 gcatcgggca attgaaaaga tgaagaaatc aaaggatgca gcatttcaga atgttttaac
     1141 acatgtttgt ttagattaag agtaaagatc atttgtacag ttcagtgatc tagtttggtg
     1201 tgtcctctta tcagttagtg gaaatagaac ggaaagagtg ctctttaaac aatgagggag
     1261 ctcagtgttt atggttttat actctgaatt ctaagttatt gagatatagt tgttacatag
     1321 gtggtattac tgttggtcaa aaatcatgag gaggaacagt tgaatccagc ctgaacgtgg
     1381 gtgcttgtgt ttgacctttt cagccatata ttgtacagcc ttatagaatc taagctggtc
     1441 ttaaagtcat aaatgattca ttgggtcatt agtgagaaac ggggatgtgg ttaggtgctg
     1501 gttcctagac atgtgagtat gcgtttgtgt gtgtgcgtgt atgtatgtgt atattaaatg
     1561 tatatatcca cacattttat attgacattc tgtagatatg tttgaatata gaaacttttt
     1621 ttaccccaac tactgaatcc aggagtacca aataatatat agtaaaacta agatttaagg
     1681 ttgtgtcaaa aaggtacagt gattcagcca tttccatttg tcatttgttt caaccttttt
     1741 taagttgagt gtttttattt ctgcagttat tagttggatc ctccacatct tgcatatata
     1801 catgggctca attattatgt ttgtcaggat aatcaaatga aaatactagt tcagtgatca
     1861 gcattgaatg gttgttaggc agccatgtgc tcaacactga tttcacctct tgagtataaa
     1921 ctttttaaat ttaaattggt ttacatgaaa gtggattaaa aggcctttca aaagaatggg
     1981 tttgaaaaac ctcagtaccc tttaatacat gtacatttct ttcctttttt catttaatgt
     2041 aacatgtctg ttgtaactat gtttcttaaa tattatttta aggttatgtg ttctttaatt
     2101 atggtcaaat ataatttggt caccaaaaat gaaataatag tttaaaacaa gtagctgtta
     2161 ctaagtgtgc taaaaatact cattttataa ttaattttag ttttcttagt atattattat
     2221 aaattgtgcc ctaagtcagg tacaaatgta cacatcaaaa tgcccatatt gtatctatct
     2281 gtagtcgttt aatgtgaatt atatgtgaat ttttttcaaa attttactaa ccagaattct
     2341 gttataggca cctaaccacg cagcatgagg aaaacggcac aacacaatct tgaggtgcct
     2401 tctgaatcat cagattaaat tatgcttcat atgtttttgc ttttactgta tttctttaaa
     2461 aactctaaat ctttattcat gtgtcactgg attaatttat ctgataatgt gtctcacaag
     2521 aatctgttag atcgtttatt cttcagttgt actttgaatg gtggggtgga agtttcaggt
     2581 gaacaatgga taacaaaaag caagttatgg aagattgtga agaggatgga aaaactgaat
     2641 acaagatacc aaaaatgaaa aaaagtgtcc catttttaat aactatattc tattatttta
     2701 taaatgtgta ataaaggggt ccctctttat tggttgttct ccacttaatc tttggtcttt
     2761 ttcagtaatt ttaagttttc tgggattttt tttggtttat aaaacttgtg tttagacttt
     2821 atcttgctat ggagttttca cacttctata gcacatatcc tagtatctag tcatttctgt
     2881 tttaatatga atttcagtaa tttaatttta atctggtgac atattaatcg aaaataagga
     2941 gtaatgtata cctccacatg tcctttcttt ttgtcttctc ttaaattcac aatatccagt
     3001 aggagtggtt attcaatttc ttcgtggttt taatcatcaa atgaagttag agaagtatac
     3061 taatcccagc aactatgact catctaggca tgttaagacc ataaagtaat tcaggaaact
     3121 attttcctga tttttaaata acttttagtg ttatgtaaca tctatccttc tgttttagac
     3181 atgcatttca catatagttg aattctagat tctaagataa ttcattttgg gtaatacttc
     3241 agagtactgg atctagaatc aggcttcctg aatttaaact caggctcccc attaactgtg
     3301 tgtctgtgag cccagtttct catctgtaaa atggggcaac agtggcactc atcttaaagg
     3361 gttggataat aaaataatgc atgtaaggcc ctcagcatag tgcctggcac agaattactg
     3421 ctcaaatgtt agctgtcgta ttaatattgt cacttttgca cactgatgta catttcctgt
     3481 tgaccaggct cattctttaa gcattctcca tgcttaaacc agttccataa tccctaggcc
     3541 tgtactccag ggattgagac tgaaaggatc atttatgcca tgtttctcta aaagcatcat
     3601 tgctggaaga cttttgataa gtctgatgtg tctcaagcta ttctcaggcc ttttttgtag
     3661 agtttagaaa tgaagtattt gaatcaattt agtatctcct ttactatgtt tctcctttta
     3721 atctcagcca accccctacc tgcaggtaaa cccagcattc attaagagct gggttggggt
     3781 actctattct gtatgcatca taatagctta acattattta gtagctgtaa cttacaggtt
     3841 taatgctaga tgaggatgtc tcaagccgtg agtgtgcttg tgtaaaaatg gtggcaacat
     3901 catctcgttg gtaggaattt tttacttgaa ttgttatttt gggaaaatgt taacagattt
     3961 cttctggata aagaaaataa attggatgat gtatatttta tgtttctttt tagcttctct
     4021 taaaatcaga atattgaaca gaattctgat atgctgaata tatatagtgc atggctgaaa
     4081 ctccagcacc aactgggtgc ttcaaatgaa gtcatagaat aattccatct agagctgaca
     4141 gaaatctttc agagccttca ttattaaatt tgttatagat ttagttatca aagatagagt
     4201 tctctaatct tttttttaaa gctaaagttc tctttattta catgtatagg aaaacattct
     4261 gcctaaatca tgatgttaat gaaaatcata ttgaggagaa cttgaacctt attaaatatg
     4321 agcttctaac ataa
//
