LOCUS       NM_152285               1556 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens arrestin domain containing 1 (ARRDC1), transcript
            variant 1, mRNA.
ACCESSION   NM_152285
VERSION     NM_152285.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1556)
  AUTHORS   Lee,K.T., Pranoto,I.K.A., Kim,S.Y., Choi,H.J., To,N.B., Chae,H.,
            Lee,J.Y., Kim,J.E., Kwon,Y.V. and Nam,J.W.
  TITLE     Comparative interactome analysis of alpha-arrestin families in
            human and Drosophila
  JOURNAL   Elife 12, 88328 (2024)
   PUBMED   38270169
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1556)
  AUTHORS   Zhao,Q., Jiang,F., Zhuang,H., Chu,Y., Zhang,F. and Wang,C.
  TITLE     MicroRNA miR-124-3p suppresses proliferation and
            epithelial-mesenchymal transition of hepatocellular carcinoma via
            ARRDC1 (arrestin domain containing 1)
  JOURNAL   Bioengineered 13 (4), 8255-8265 (2022)
   PUBMED   35300565
  REMARK    GeneRIF: MicroRNA miR-124-3p suppresses proliferation and
            epithelial-mesenchymal transition of hepatocellular carcinoma via
            ARRDC1 (arrestin domain containing 1).
REFERENCE   3  (bases 1 to 1556)
  AUTHORS   Xu,H., Yu,X., Yang,Z., Song,Q., Cheng,S., He,Z. and Dai,L.
  TITLE     PAX5-activated lncRNA ARRDC1-AS1 accelerates the autophagy and
            progression of DLBCL through sponging miR-2355-5p to regulate ATG5
  JOURNAL   Life Sci 286, 119932 (2021)
   PUBMED   34499929
  REMARK    GeneRIF: PAX5-activated lncRNA ARRDC1-AS1 accelerates the autophagy
            and progression of DLBCL through sponging miR-2355-5p to regulate
            ATG5.
REFERENCE   4  (bases 1 to 1556)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (bases 1 to 1556)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (bases 1 to 1556)
  AUTHORS   Nabhan,J.F., Hu,R., Oh,R.S., Cohen,S.N. and Lu,Q.
  TITLE     Formation and release of arrestin domain-containing protein
            1-mediated microvesicles (ARMMs) at plasma membrane by recruitment
            of TSG101 protein
  JOURNAL   Proc Natl Acad Sci U S A 109 (11), 4146-4151 (2012)
   PUBMED   22315426
REFERENCE   7  (bases 1 to 1556)
  AUTHORS   Shea,F.F., Rowell,J.L., Li,Y., Chang,T.H. and Alvarez,C.E.
  TITLE     Mammalian alpha arrestins link activated seven transmembrane
            receptors to Nedd4 family e3 ubiquitin ligases and interact with
            beta arrestins
  JOURNAL   PLoS One 7 (12), e50557 (2012)
   PUBMED   23236378
REFERENCE   8  (bases 1 to 1556)
  AUTHORS   Rauch,S. and Martin-Serrano,J.
  TITLE     Multiple interactions between the ESCRT machinery and
            arrestin-related proteins: implications for PPXY-dependent budding
  JOURNAL   J Virol 85 (7), 3546-3556 (2011)
   PUBMED   21191027
  REMARK    GeneRIF: The authors show that WWP1 changes the ubiquitination
            status of ARRDC1, suggesting that the arrestins may provide a
            platform for ubiquitination in PPXY-dependent budding.
REFERENCE   9  (bases 1 to 1556)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   10 (bases 1 to 1556)
  AUTHORS   Humphray,S.J., Oliver,K., Hunt,A.R., Plumb,R.W., Loveland,J.E.,
            Howe,K.L., Andrews,T.D., Searle,S., Hunt,S.E., Scott,C.E.,
            Jones,M.C., Ainscough,R., Almeida,J.P., Ambrose,K.D., Ashwell,R.I.,
            Babbage,A.K., Babbage,S., Bagguley,C.L., Bailey,J., Banerjee,R.,
            Barker,D.J., Barlow,K.F., Bates,K., Beasley,H., Beasley,O.,
            Bird,C.P., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.,
            Burrill,W., Burton,J., Carder,C., Carter,N.P., Chapman,J.C.,
            Chen,Y., Clarke,G., Clark,S.Y., Clee,C.M., Clegg,S., Collier,R.E.,
            Corby,N., Crosier,M., Cummings,A.T., Davies,J., Dhami,P., Dunn,M.,
            Dutta,I., Dyer,L.W., Earthrowl,M.E., Faulkner,L., Fleming,C.J.,
            Frankish,A., Frankland,J.A., French,L., Fricker,D.G., Garner,P.,
            Garnett,J., Ghori,J., Gilbert,J.G., Glison,C., Grafham,D.V.,
            Gribble,S., Griffiths,C., Griffiths-Jones,S., Grocock,R., Guy,J.,
            Hall,R.E., Hammond,S., Harley,J.L., Harrison,E.S., Hart,E.A.,
            Heath,P.D., Henderson,C.D., Hopkins,B.L., Howard,P.J., Howden,P.J.,
            Huckle,E., Johnson,C., Johnson,D., Joy,A.A., Kay,M., Keenan,S.,
            Kershaw,J.K., Kimberley,A.M., King,A., Knights,A., Laird,G.K.,
            Langford,C., Lawlor,S., Leongamornlert,D.A., Leversha,M., Lloyd,C.,
            Lloyd,D.M., Lovell,J., Martin,S., Mashreghi-Mohammadi,M.,
            Matthews,L., McLaren,S., McLay,K.E., McMurray,A., Milne,S.,
            Nickerson,T., Nisbett,J., Nordsiek,G., Pearce,A.V., Peck,A.I.,
            Porter,K.M., Pandian,R., Pelan,S., Phillimore,B., Povey,S.,
            Ramsey,Y., Rand,V., Scharfe,M., Sehra,H.K., Shownkeen,R.,
            Sims,S.K., Skuce,C.D., Smith,M., Steward,C.A., Swarbreck,D.,
            Sycamore,N., Tester,J., Thorpe,A., Tracey,A., Tromans,A.,
            Thomas,D.W., Wall,M., Wallis,J.M., West,A.P., Whitehead,S.L.,
            Willey,D.L., Williams,S.A., Wilming,L., Wray,P.W., Young,L.,
            Ashurst,J.L., Coulson,A., Blocker,H., Durbin,R., Sulston,J.E.,
            Hubbard,T., Jackson,M.J., Bentley,D.R., Beck,S., Rogers,J. and
            Dunham,I.
  TITLE     DNA sequence and analysis of human chromosome 9
  JOURNAL   Nature 429 (6990), 369-374 (2004)
   PUBMED   15164053
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC032346.1 and AA552336.1.
            
            On Nov 22, 2018 this sequence version replaced NM_152285.3.
            
            Transcript Variant: This variant (1) represents the shorter
            transcript and encodes the shorter isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ420420.1, SRR1660807.74277.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000371421.9/ ENSP00000360475.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1533              BC032346.1         33-1565
            1534-1556           AA552336.1         24-46               c
FEATURES             Location/Qualifiers
     source          1..1556
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q34.3"
     gene            1..1556
                     /gene="ARRDC1"
                     /note="arrestin domain containing 1"
                     /db_xref="GeneID:92714"
                     /db_xref="HGNC:HGNC:28633"
                     /db_xref="MIM:619768"
     exon            1..150
                     /gene="ARRDC1"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..1334
                     /gene="ARRDC1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     arrestin domain-containing protein 1; alpha-arrestin 1"
                     /codon_start=1
                     /product="arrestin domain-containing protein 1 isoform 1"
                     /protein_id="NP_689498.1"
                     /db_xref="CCDS:CCDS7049.1"
                     /db_xref="GeneID:92714"
                     /db_xref="HGNC:HGNC:28633"
                     /db_xref="MIM:619768"
                     /translation="MGRVQLFEISLSHGRVVYSPGEPLAGTVRVRLGAPLPFRAIRVT
                     CIGSCGVSNKANDTAWVVEEGYFNSSLSLADKGSLPAGEHSFPFQFLLPATAPTSFEG
                     PFGKIVHQVRAAIHTPRFSKDHKCSLVFYILSPLNLNSIPDIEQPNVASATKKFSYKL
                     VKTGSVVLTASTDLRGYVVGQALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHD
                     VRTIAEVEGAGVKAWRRAQWHEQILVPALPQSALPGCSLIHIDYYLQVSLKAPEATVT
                     LPVFIGNIAVNHAPVSPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFL
                     STKSHSQRQPLLATLSSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGP
                     VPTTSTLILPPEYSSWGYPYEAPPSYEQSCGGVEPSLTPES"
     exon            151..261
                     /gene="ARRDC1"
                     /inference="alignment:Splign:2.1.0"
     exon            262..312
                     /gene="ARRDC1"
                     /inference="alignment:Splign:2.1.0"
     exon            313..467
                     /gene="ARRDC1"
                     /inference="alignment:Splign:2.1.0"
     exon            468..650
                     /gene="ARRDC1"
                     /inference="alignment:Splign:2.1.0"
     exon            651..827
                     /gene="ARRDC1"
                     /inference="alignment:Splign:2.1.0"
     exon            828..1269
                     /gene="ARRDC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1556
                     /gene="ARRDC1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1535..1540
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ARRDC1"
                     /note="hexamer: AATAAA"
     polyA_site      1556
                     /gene="ARRDC1"
                     /note="major polyA site"
ORIGIN      
        1 gtcgctgcgc ggctggccgg tgaggccgcg gcatggggcg agtgcagctc ttcgagatca
       61 gcctgagcca cggccgcgtc gtctacagcc ccggggagcc gttggctggg accgtgcgcg
      121 tgcgcctggg ggcaccgctg ccgttccgag ccatccgggt gacctgcata ggttcctgcg
      181 gggtctccaa caaggctaat gacacagcgt gggtagtgga ggagggttac ttcaacagtt
      241 ccctgtcgct ggcagacaag gggagcctgc ccgctggaga gcacagcttc cccttccagt
      301 tcctgcttcc tgccactgca cccacgtcct ttgagggtcc tttcgggaag atcgtgcacc
      361 aggtgagggc cgccatccac acgccacggt tttccaagga tcacaagtgc agcctcgtgt
      421 tctatatctt gagccccttg aacctgaaca gcatcccaga cattgagcaa cccaacgtgg
      481 cctctgccac caagaagttc tcctacaagc tggtgaagac gggcagcgtg gtcctcacag
      541 ccagcactga tctccgcggc tatgtggtgg ggcaggcact gcagctgcat gccgacgttg
      601 agaaccagtc aggcaaggac accagccctg tggtggccag tctgctgcag aaagtgtcct
      661 ataaggccaa gcgctggatc cacgacgtac ggaccattgc ggaggtggag ggtgcgggcg
      721 tcaaggcctg gcggcgggcg cagtggcacg agcagatcct ggtgcctgcc ttgccccagt
      781 cggccctgcc gggctgcagc ctcatccaca tcgactacta cttacaggtc tctctgaagg
      841 cgccggaagc tactgtgacc ctcccggtct tcattggcaa tattgctgtg aaccatgccc
      901 cagtgagccc ccggccaggc ctggggctgc ctcctggggc cccacccctg gtggtgcctt
      961 ccgcaccacc ccaggaggag gctgaggctg aggctgcggc tggcggcccc cacttcttgg
     1021 accccgtctt cctctccacc aagagccatt cgcagcggca gcccctgctg gccaccttga
     1081 gttctgtgcc tggtgcgccg gagccctgcc ctcaggatgg cagccctgcc tcacacccgc
     1141 tgcaccctcc cttgtgcatt tcaacaggtg ccactgtccc ctactttgca gagggctccg
     1201 gggggccagt gcccactacc agcaccttga ttcttcctcc agagtacagt tcttggggct
     1261 acccctatga ggccccaccg tcttatgagc agagctgcgg cggcgtggaa cccagcctga
     1321 cccctgagag ctgaccccgt gctgccttct ccaggcaggc ctggcctctg ccctgggact
     1381 ggggcgccca gggcctcgtg ccttctctct tggcctagcc tggcccactc aggacctgcc
     1441 cagcctctgc cagctcctct ggcatccgcc ctcttctccc tggggctggg gtgggggtgg
     1501 cagggagctg ggacctggag agacaactcc tgtaaataaa acactttatt tgtaga
//
