LOCUS       NM_001039083            5240 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens ARF like GTPase 17B (ARL17B), transcript variant 1,
            mRNA.
ACCESSION   NM_001039083
VERSION     NM_001039083.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5240)
  AUTHORS   Choudhary,C., Kumar,C., Gnad,F., Nielsen,M.L., Rehman,M.,
            Walther,T.C., Olsen,J.V. and Mann,M.
  TITLE     Lysine acetylation targets protein complexes and co-regulates major
            cellular functions
  JOURNAL   Science 325 (5942), 834-840 (2009)
   PUBMED   19608861
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC217777.1.
            
            On Dec 3, 2019 this sequence version replaced NM_001039083.4.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11853562.15143.1,
                                           SRR11853559.14400.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2146411 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000450673.4/ ENSP00000404247.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-91                AC217777.1         81961-82051         c
            92-256              AC217777.1         78535-78699         c
            257-367             AC217777.1         73105-73215         c
            368-5240            AC217777.1         55187-60059         c
FEATURES             Location/Qualifiers
     source          1..5240
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.31"
     gene            1..5240
                     /gene="ARL17B"
                     /gene_synonym="ARL17; ARL17A"
                     /note="ARF like GTPase 17B"
                     /db_xref="GeneID:100506084"
                     /db_xref="HGNC:HGNC:32387"
     exon            1..91
                     /gene="ARL17B"
                     /gene_synonym="ARL17; ARL17A"
                     /inference="alignment:Splign:2.1.0"
     exon            92..256
                     /gene="ARL17B"
                     /gene_synonym="ARL17; ARL17A"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..642
                     /gene="ARL17B"
                     /gene_synonym="ARL17; ARL17A"
                     /note="isoform a is encoded by transcript variant 1;
                     ADP-ribosylation factor-like protein 17; ADP-ribosylation
                     factor 7; ADP-ribosylation factor-like 17B; ADP
                     ribosylation factor like GTPase 17B"
                     /codon_start=1
                     /product="ADP-ribosylation factor-like protein 17 isoform
                     a"
                     /protein_id="NP_001034172.3"
                     /db_xref="CCDS:CCDS58557.1"
                     /db_xref="GeneID:100506084"
                     /db_xref="HGNC:HGNC:32387"
                     /translation="MGNIFEKLFKSLLGKKKMRILILSLDTAGKTTILYKLKLGETVP
                     AVPTVGFCVETVEYKNNTFAVWDVGSHFKIRPLWQHFFQNTKGARSPGSTHQGSLASG
                     VLPIKCSHVEFGMWKGGRSHPFLPHSSRCAGSGGQLDSILPHQSPAWGPWGCKDLSSG
                     FPSFLTSSILWKSAVVK"
     exon            257..367
                     /gene="ARL17B"
                     /gene_synonym="ARL17; ARL17A"
                     /inference="alignment:Splign:2.1.0"
     exon            368..5240
                     /gene="ARL17B"
                     /gene_synonym="ARL17; ARL17A"
                     /inference="alignment:Splign:2.1.0"
     regulatory      797..802
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ARL17B"
                     /gene_synonym="ARL17; ARL17A"
                     /note="hexamer: AATATA"
     polyA_site      835
                     /gene="ARL17B"
                     /gene_synonym="ARL17; ARL17A"
                     /note="major polyA site"
ORIGIN      
        1 acgcctgtcg tggtttagct gaactgagct gaaatcctaa aggccgcgga gtcggcggtg
       61 ttgtaggtag cggtaccttg agtggcaaca gaattcgatt aaattacaat gggaaacatt
      121 tttgaaaagc tctttaaaag tctacttggg aaaaaaaaga tgcggattct tatattgagt
      181 ttggatacag ctggaaaaac caccatcttg tataaattga agctggggga gactgtgcct
      241 gccgtcccta cagtaggttt ctgtgtggag acagtagaat ataaaaataa caccttcgct
      301 gtctgggatg ttggcagcca cttcaaaatc agacctctgt ggcagcattt tttccagaac
      361 acaaaaggtg ccagaagccc aggaagcaca catcaaggct cacttgccag cggggtgctg
      421 ccaataaaat gtagtcacgt ggaatttgga atgtggaaag gaggtagaag tcatcctttc
      481 ctcccccata gcagcaggtg tgcaggctct ggtggtcagc tggactccat actcccccac
      541 cagtcaccag cctggggacc gtggggctgc aaggacctca gcagcggttt cccaagtttc
      601 ctgacttctt ccatcctctg gaaatcagct gtggtaaagt agcctgaaag ccagtggtgc
      661 aaccccatcc ccacaacctt caccacctct agcacctcca gtgataagca ctaattgcct
      721 atatacaacc cttttttgtt tgaaatatct agagtaattt ctgttttcct atctggggta
      781 gtgtaacata agaagaaata tatatttggt ctctgacccc agttcctaac acaaagctcc
      841 taaaaccctt ggaaattcct gaatgatggc ggtgctaaga gcattgtcct ttgttaattt
      901 atcatttttc ttttctccta ggtgtttttt cctttttaaa ctttcctttt aggttagggg
      961 gtacatatgc acgttcgtta tatagctaaa cttgtgtcat gggggtttgt tgtacagatt
     1021 atttcatcac ccaggtacca agcctagtac ccaatagttt tttctgctcc tctccctcct
     1081 cccaccctcc accctcaggt agggcccagt gtctgttgtt tatgagttct catcattttg
     1141 ctcccactta aaagaacata cagtatttgg ttttctgttc ctgtcttagt ttgctgagga
     1201 taatggcctc tagctccatc tgtgttcctg caaaagacat gatctcgctg ttttttatgg
     1261 ttgcacatct tttgttctaa catttggtcc ttaaacctgg ttcctgacac agagctccta
     1321 aatcccttgg aattttctgg gtgatagaag cgtcctttgt tctcatgagg tgactcttgg
     1381 tgggctcctt atttggggac tggtcaccaa aaagacctat ggttggaagc gttgtgctgt
     1441 cagccccatt ccccatcctc tggcgtgggg agtagagctg gagctcaatc atgcctacgt
     1501 gataaagcct ccagaaaact ccttaaaaga caggacttgg agagcttccg ggttggcgaa
     1561 cacatccatg ttccaggaga gtggtgcacc ccaactccac aaggaccctt ccaaacctca
     1621 ccctgtgtat ctcttcaact ggcttcatca tttgtgtcct ttaaaatatc ctttgtaata
     1681 aatcagcact agtaagaaaa ctgttttcct gggttccatg agctgttcta gcaaatgttc
     1741 aaacctgagg agggagttgt ggggacctcc aatttacagc cagttggtca gatgcatagg
     1801 tgatgcttgg ccttgcacct ggggtctgac atgcggatgg ttctgtgtga ctgagccctt
     1861 aacctgtgga gtctggtgct cactctgctt agggcttctc ttgccttttt agtgtccttc
     1921 taggcggcct ttccttcctc ttgtcagctc agaaaacttt tcttccactt cccttcttct
     1981 aaaccatccc ttacatctac tcctttccag ccgaccaaga gcagaaccac ggctggttcc
     2041 actgccacca tgctgtccca cactgtctcc tcaggatgta ttcagatgtc cagccctccc
     2101 cccagtctag gagccccccc tttgaggaaa gggatgctgg cctagtcaac tctttcccag
     2161 caccaggtac agcatctggc acgttccatc tttttcatgg actctcccca ggcggcctga
     2221 ccttccctcc tctgaaccgg tgcatttctt gtctgcatca tgtttgccct aatcagatat
     2281 caccttattt cctcttttaa aaaatgcttt gtttctctgg caggcttcat cggaatcaca
     2341 attttcattc atttagtaac tgttgttgtt tattctatgt atttttgcag gaggcctgag
     2401 gtgggctgtg ttctcctcct atggcagggc ttcactctcc tcctcctccg ttggggcttc
     2461 gctgtccctg ggataagaat aacaatgcca aggttttcat tcttgaaagg agcaattaag
     2521 cttctcaccc cctcctcatt ttagatggga actgtgaggg ccccatcatt tacccagggt
     2581 ccctgttgag gatcttgtcc tcattagatg acttcttgtg cagcttccat gcatgattat
     2641 ttattcttgt ggcactgaga ggtttgtaca gatctttaaa ccagagcggc tgtccaaatg
     2701 aggaaagtcc atcctagaag atagaaaggg aaatattaat tttgcatgtc ctctgctttc
     2761 cctggccaca gcaatgaatc ctccaatgta cctgactctc ccttcgcgaa gagcatcccc
     2821 tccatggcag aaatctgaaa atgcccctgg ggagacacat gcacaagaca gtgagtgatg
     2881 cagccgtttc ccacgtatct cacaatgtac ttctctggtc ttattaggac taaatgagta
     2941 tctcagtcca taatcacagg gagaaccacc accacagacc acatacccgg ggtcttgaaa
     3001 ataattccat gcatgtggga ctttcagaag ctctccatgt ctgcccagaa gggccccaca
     3061 atatactggg gggactttgt atgtggctca gcatggagca ggggcaggat tttcagtccc
     3121 actcactccc ttggccaagt gcccttgtgc agtgaacaaa ctgcacaacc atgctgggca
     3181 gaagcatttt atatcagtcc ccttcggact tagtctcaca ggcatcattt gatgggggat
     3241 gggagatgaa gtggttcttc gttttctaga tactttattc tataagttgg atcacctcaa
     3301 gcaaatgcgt gagtgcagct agccaagttc tctatctcac agtcttcata tggctggctg
     3361 tcgctgatga gtgagtgagc tacgaaatca gcttaaagca caacatgtta tttttgaatt
     3421 tgaataaaat aggaaaaggc agagtgcatt gtgtgaccat ggggtaagta agacactctc
     3481 cctttctcct tctcagtttt cctgtcataa aaggacaaac tactatctaa ggtctccgta
     3541 gttaaaattc ttttttgttg tttttttttt atttgagaca gtttggctca ttccccaggc
     3601 tggagtgcaa tggtgctatc ttggctccct gcaacctgcg cctcctgggc tcaagcagtt
     3661 ctcctgcctc agcctcccaa gtagctggga ttacacgcct gcgccaccac acccagctaa
     3721 tttagtattt ttagtagaga tggggtttca ccatgttggt caggctggtc acgagctcct
     3781 aacctcaagt gatcccaaag tgctgtgatt acaggcgtga gccatcctgc ctggcctttc
     3841 tggttaaaat tctgtgaggt ttgcataaaa ggaatagagt aggggcccaa aaaccagtaa
     3901 gatgagaaaa tagtgtttcc tcagttctag gatccagggg aaaaaaaaag aaataaaaga
     3961 gaaaatactg tttcctgcca cttaagagga aggactcgca tatcctacct tccatcagcc
     4021 ttgaaggaga caagtgccct ctctctcaca cccggtggcc ttcccttccc ctttcccaga
     4081 gcctccaaga aggcccctgg cctggcctga tgcccaccat cagcagcaat aggcaccaaa
     4141 acctttctcc ttcctatccc tccccacctc ccgaaagggc tggggacagc aggtgtgtcc
     4201 ttgttagttc catccagctc agctttggct ggggagctaa tttcactgga gccaggctaa
     4261 gcattagggt aagtatttgt cctgtcttgg gcagtttcct cactgaaaaa tgagggcaga
     4321 gttctaagcc ctcctctaat tctaaaattc taattaaaac gtcgcgagac tagtggtgca
     4381 tgcctgtaat cccagctact cgggaggctg aggcaggaga atcgcttgaa cctgggaagt
     4441 ggaggttgcc gtgagccgag atcgtgtcat tgcactccag cctggcaaca agagggaaac
     4501 tccatctcaa aagagaagaa aaaaaaaatc accagactaa tatttacctt gagaatcctt
     4561 cttcatcttc ttgtaatgac cttcggtgac aacatatctg ttttagaaga aaacgcaatt
     4621 aagattatct atgacaacaa ccaccatctc caaatctgta ttgattcctt ttattcatta
     4681 taagtctcat gtacctgatg aggtaacttt tttgaagaca ggaattgtat gctgtgtaac
     4741 actgctttga ttcttccata gttcagtcat ccttgctatc ttgcggggga ttggttctag
     4801 gataccgccc ccacaccata ccagaatctg tggatgctca atcccttaca tataatggtg
     4861 taatatttgc ttataaccaa cacgcatccc ccctatactt tatttactta gcgacaggat
     4921 tgccctctgt tgcttacgct ggagtgcagt gtcatcctct gttactcagg atggagtgcg
     4981 gtgtcacgat cacagctcac tgtagcctca acctcctggg ctccagtgat ccgcccacct
     5041 cagcctcttg agtagctgag actacaggtg catactacca cacctggcta tttttttttt
     5101 aatttttaat aaagacaagg tctcactatg ctgcccaggt tggcctccca atgtgttggg
     5161 attacaagtg tgagccacca tgcctggccc catgtaattt aagtcatcac taataaaatg
     5221 tatacatatt gtacattgtt
//
