LOCUS       NM_025047               1289 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens ARF like GTPase 14 (ARL14), mRNA.
ACCESSION   NM_025047
VERSION     NM_025047.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1289)
  AUTHORS   Yang,F., Li,T., Peng,Z., Liu,Y. and Guo,Y.
  TITLE     The amphipathic helices of Arfrp1 and Arl14 are sufficient to
            determine subcellular localizations
  JOURNAL   J Biol Chem 295 (49), 16643-16654 (2020)
   PUBMED   32972971
  REMARK    GeneRIF: The amphipathic helices of Arfrp1 and Arl14 are sufficient
            to determine subcellular localizations.
REFERENCE   2  (bases 1 to 1289)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 1289)
  AUTHORS   Senapati,S., Singh,S., Das,M., Kumar,A., Gupta,R., Kumar,U.,
            Jain,S., Juyal,R.C. and Thelma,B.K.
  TITLE     Genome-wide analysis of methotrexate pharmacogenomics in rheumatoid
            arthritis shows multiple novel risk variants and leads for TYMS
            regulation
  JOURNAL   Pharmacogenet Genomics 24 (4), 211-219 (2014)
   PUBMED   24583629
REFERENCE   4  (bases 1 to 1289)
  AUTHORS   Paul,P., van den Hoorn,T., Jongsma,M.L., Bakker,M.J., Hengeveld,R.,
            Janssen,L., Cresswell,P., Egan,D.A., van Ham,M., Ten Brinke,A.,
            Ovaa,H., Beijersbergen,R.L., Kuijl,C. and Neefjes,J.
  TITLE     A Genome-wide multidimensional RNAi screen reveals pathways
            controlling MHC class II antigen presentation
  JOURNAL   Cell 145 (2), 268-283 (2011)
   PUBMED   21458045
REFERENCE   5  (bases 1 to 1289)
  AUTHORS   Hirschfield,G.M., Liu,X., Xu,C., Lu,Y., Xie,G., Lu,Y., Gu,X.,
            Walker,E.J., Jing,K., Juran,B.D., Mason,A.L., Myers,R.P.,
            Peltekian,K.M., Ghent,C.N., Coltescu,C., Atkinson,E.J.,
            Heathcote,E.J., Lazaridis,K.N., Amos,C.I. and Siminovitch,K.A.
  TITLE     Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2
            variants
  JOURNAL   N Engl J Med 360 (24), 2544-2555 (2009)
   PUBMED   19458352
  REMARK    Erratum:[N Engl J Med. 2009 Jun 25;360(26):2797-8]
REFERENCE   6  (bases 1 to 1289)
  AUTHORS   Oh,J.H., Yang,J.O., Hahn,Y., Kim,M.R., Byun,S.S., Jeon,Y.J.,
            Kim,J.M., Song,K.S., Noh,S.M., Kim,S., Yoo,H.S., Kim,Y.S. and
            Kim,N.S.
  TITLE     Transcriptome analysis of human gastric cancer
  JOURNAL   Mamm Genome 16 (12), 942-954 (2005)
   PUBMED   16341674
REFERENCE   7  (bases 1 to 1289)
  AUTHORS   Colicelli,J.
  TITLE     Human RAS superfamily proteins and related GTPases
  JOURNAL   Sci STKE 2004 (250), RE13 (2004)
   PUBMED   15367757
  REMARK    Review article
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BM760777.1 and BC034354.1.
            
            On May 17, 2019 this sequence version replaced NM_025047.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK026248.1, BC034354.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000320767.4/ ENSP00000323847.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                BM760777.1         1-17
            18-145              BC034354.1         1-128
            146-154             BM760777.1         146-154
            155-358             BC034354.1         138-341
            359-710             BM760777.1         360-711
            711-1289            BC034354.1         694-1272
FEATURES             Location/Qualifiers
     source          1..1289
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q25.33"
     gene            1..1289
                     /gene="ARL14"
                     /gene_synonym="ARF7"
                     /note="ARF like GTPase 14"
                     /db_xref="GeneID:80117"
                     /db_xref="HGNC:HGNC:22974"
                     /db_xref="MIM:614439"
     exon            1..1289
                     /gene="ARL14"
                     /gene_synonym="ARF7"
                     /inference="alignment:Splign:2.1.0"
     CDS             188..766
                     /gene="ARL14"
                     /gene_synonym="ARF7"
                     /note="ADP-ribosylation factor-like 14; ADP-ribosylation
                     factor 7; ADP ribosylation factor like GTPase 14"
                     /codon_start=1
                     /product="ADP-ribosylation factor-like protein 14"
                     /protein_id="NP_079323.1"
                     /db_xref="CCDS:CCDS3192.1"
                     /db_xref="GeneID:80117"
                     /db_xref="HGNC:HGNC:22974"
                     /db_xref="MIM:614439"
                     /translation="MGSLGSKNPQTKQAQVLLLGLDSAGKSTLLYKLKLAKDITTIPT
                     IGFNVEMIELERNLSLTVWDVGGQEKMRTVWGCYCENTDGLVYVVDSTDKQRLEESQR
                     QFEHILKNEHIKNVPVVLLANKQDMPGALTAEDITRMFKVKKLCSDRNWYVQPCCALT
                     GEGLAQGFRKLTGFVKSHMKSRGDTLAFFKQN"
     regulatory      1266..1271
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ARL14"
                     /gene_synonym="ARF7"
                     /note="hexamer: AATAAA"
     polyA_site      1289
                     /gene="ARL14"
                     /gene_synonym="ARF7"
                     /note="major polyA site"
ORIGIN      
        1 gataagctac aacataaaca catctaggtt cttgttctta gaatacagca tgaagaattt
       61 gctttcttct ttcttcctaa cattttcatg tgagatccag aaaggacaca ttgtctctgg
      121 ccattcgaag aaagaaagaa agaaaaaaaa aaaaggtatt tagagacaga gagagaaaaa
      181 ggctgaaatg ggttcgctgg gttctaaaaa tccgcaaacc aaacaagccc aagttcttct
      241 tttgggactt gactcagctg ggaagtctac tctcctttat aaattaaagc ttgctaagga
      301 tattaccacc atccctacaa taggtttcaa tgtggaaatg atcgagttgg aaaggaatct
      361 ttcactcaca gtctgggatg ttggaggaca ggaaaaaatg agaactgttt ggggctgtta
      421 ctgtgagaac accgatgggc tggtgtatgt tgtggacagt acagacaaac agcgactgga
      481 agagtctcag agacagtttg agcacatttt gaagaatgaa cacattaaaa atgtgcctgt
      541 tgttctatta gccaacaaac aagacatgcc tggagctctg actgctgagg acatcaccag
      601 aatgttcaaa gtgaagaagc tttgcagtga ccggaactgg tatgtgcaac cctgctgtgc
      661 cctcacaggg gaggggctgg cccaggggtt caggaaatta actggatttg tgaagagcca
      721 catgaaatca agaggagaca ctttggcgtt cttcaagcag aactgaggct gcgaaaaatc
      781 caagtctcta cagagacact gatgaagttg aaagggtaat tgtttttcca tgccaaatga
      841 ggaaatcaaa ttaatgagtt gacaaacttt tcctgagatg ttatttcatc tacatttagt
      901 taaacaactt agaatgatat ctagaaaata tttattttca gccaggaact ttagcaaact
      961 gtggcaatga tcactgggaa tgaaaacgta taatgttcta caatttttgt tatcacattg
     1021 gatgactttg aatatagtag tgacacttgg gaccaaataa attattttat atgactacta
     1081 gaacaaagtt ttagtaagct gtctgctaat agagtcagaa ttcttccaga ttgtttccag
     1141 ctgtaacagg tattgaattt ccaccgtgct cctatgtaac agctgggtgg tgtaaaaaat
     1201 gaacttcaaa ttatggagtg gaaaaagcgt aatgttaata tcttgtaaat tcgtattccc
     1261 tattaaataa agctttctta ttccctaaa
//
