LOCUS       XM_017005535            4908 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ariadne RBR E3 ubiquitin protein ligase 2
            (ARIH2), transcript variant X6, mRNA.
ACCESSION   XM_017005535
VERSION     XM_017005535.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017005535.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4908
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..4908
                     /gene="ARIH2"
                     /gene_synonym="ARI2; TRIAD1"
                     /note="ariadne RBR E3 ubiquitin protein ligase 2; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 34 ESTs, 1039 long SRA reads, 2 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 11 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10425"
                     /db_xref="HGNC:HGNC:690"
                     /db_xref="MIM:605615"
     CDS             462..1796
                     /gene="ARIH2"
                     /gene_synonym="ARI2; TRIAD1"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase ARIH2 isoform X3"
                     /protein_id="XP_016861024.1"
                     /db_xref="GeneID:10425"
                     /db_xref="HGNC:HGNC:690"
                     /db_xref="MIM:605615"
                     /translation="MLTAISCILPMALVSHSVAKLILVNFHWQVSEILDRYKSNSAQL
                     LVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVK
                     DGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGAD
                     CPMVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYI
                     SAHTKDCPKCNICIEKNGGCNHMQCSKCKHGEFQAWCVRPSGTFLWLGLRYYLNFCWM
                     CLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEA
                     QTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRKK
                     LFEYQQAQLEAEIENLSWKVERADSYDRGDLENQMHIAEQRRRTLLKDFHDT"
ORIGIN      
        1 acctcttctt tttcaaataa cttaaagatc tctctgcctt taatatctgc cccctccttt
       61 acttctactt tttgtttttc tgatacatcc actaaaagta ccactttatt ttgctctgtt
      121 gaaaaattta aagtggattc ttcaggctcc agcctgattt ccttattgtt cctctcccta
      181 actcatatac ttgattttaa cctcctccaa cctattgtca gcatctccgc ccttcttgca
      241 accctcgaga gactgctaag ccctccaact ttttttaacc cgtctcagag aagctgtgtc
      301 tgacctctcc tgtatccctg tgcattcctg agggcttgga agaccttggg caccttcata
      361 cgctcttgtg gtggatgtgg gtgtggtgac aaggctggac caccggagac agacagagaa
      421 tggtcttggc gtatgggacc taatgctagc acaggccgtt gatgctcact gccatcagct
      481 gcatcctccc tatggcactg gtatctcatt cagttgctaa acttatatta gttaatttcc
      541 actggcaagt ttcagagata ttggacagat acaagtccaa ttctgctcaa ctgcttgttg
      601 aggctcgagt tcagcctaat ccatcaaaac atgttcccac atcccatccc cctcaccact
      661 gtgcagtgtg tatgcagttt gtgcgaaagg aaaacctact ctctctggcc tgtcagcacc
      721 agttttgccg cagctgctgg gagcagcact gctcagttct cgtcaaggac ggcgtgggcg
      781 tgggagtctc ttgcatggct caggactgtc cactccgtac accagaggac tttgtgtttc
      841 cattgcttcc caatgaagaa ttgagagaga aatacaggcg ctacctcttc agggactatg
      901 tggagagtca ttaccagctc cagctgtgcc ctggtgcaga ctgccccatg gttattcggg
      961 tacaggagcc tagagctcgc cgagtacagt gcaatcggtg caacgaggtc ttctgtttca
     1021 agtgtcgtca gatgtatcac gcacccacag actgtgccac aatccggaaa tggctcacga
     1081 agtgtgcaga cgactctgaa acagccaact acattagtgc tcacactaaa gactgtccca
     1141 agtgcaacat ctgcattgag aagaatggag gctgcaatca catgcaatgc tccaaatgta
     1201 aacacggtga gttccaagct tggtgtgtaa ggcccagtgg cactttcttg tggttgggtc
     1261 tccgttacta tttaaacttc tgctggatgt gtctaggaga ttggaagact catggcagtg
     1321 aatactatga gtgcagtcgt tacaaggaga atcctgacat cgtgaaccag agccaacaag
     1381 cccaggcgag ggaagccctc aagaagtact tattctactt tgagaggtgg gaaaaccaca
     1441 ataaaagctt gcagctagag gcacagacat accagcggat tcacgagaag attcaggaga
     1501 gggtcatgaa caatctgggg acatggatcg actggcagta cctacagaat gctgccaagc
     1561 tcttggccaa gtgtcgatac accctgcaat acacctaccc atatgcatat tacatggagt
     1621 ccggacccag gaagaagctg tttgaatacc agcaggctca gctggaggct gagatcgaaa
     1681 acctctcatg gaaagtggag cgtgcagaca gctatgacag aggggacttg gagaaccaga
     1741 tgcatatagc ggagcagcgg aggagaaccc tgctgaaaga tttccatgac acctaagttg
     1801 ggatgtggat gtgccggggt gaggaagatg tggctgcaag gtctcccggc tgccatactg
     1861 catgctgcag gctctgcctt tcatgacccc aggcaacagc cagggcccca ctcctgagag
     1921 acactggcaa cacctcttag ttgatttctg ttttcttctc ttttcacttt ttgtttctac
     1981 cagggtagag gccatgttga actggcctct tttcaggact tttatttccc cctggatggt
     2041 tgttgggagg gagggaaagt gttttctgaa tggctattaa tagtattaga tcattacaac
     2101 ttatgtaact ttcaaaggtt gtacaattat acaaaaaaaa aaaaaaggca aactatagga
     2161 taacacagag ccctttttga aaataaattg gcattggagt gttttaccct ctagctgttt
     2221 tacttagaat gtaacatatg ctgcctaccc acctcaaaat gtctgtactg caagagggcc
     2281 ctgggcctct gctttccata ttcacgtttg gccagagttg tagtcccaaa gaagagcatg
     2341 ggtggcagat ggtagggaat tgaactggcc tgtgcaatgg gcatggagca caaggggtca
     2401 cagcatgcct cctgccttac cgtggcagta cggagacagt ccagaacatg gtcttcttgc
     2461 cacggggtgt tgttgtctct ggtggtgctg catgtctgtg gctcaccttt attcttgaaa
     2521 ctgaggttta cctggatctg gctactgagg ctagagccca cagcagaatg gggttgggcc
     2581 tgtggccccc caaactaggg ggtgtgggtt catcacagtg ttgccttttg tctcctaaag
     2641 atagggatct acttttgaag ggaattgttc ctcccaaata aatttgcttt accttggtcc
     2701 tttcttttgt gccagtattc aagtggtata gctctgagca gggtcacatt tggccaaacc
     2761 tgacactgtc ttgctgcatt ctcctttggc aaacatcagg gtcagaattc aggatagccc
     2821 ttcctagggc actggacttt ctggcatggg ggctgtgttt gcacaagtta ttttcatgtt
     2881 acctggagag tgtccagagg ctgctctgag gctgaggtgt gttccccctt gcctggttcc
     2941 agctgtcaga gggataccat cctagggtct gggaatccaa ggccacgaga ctccttggtt
     3001 tgtggtccga gatcctgtac taaggagggt ctggccagag gaacagacca gcttttgcac
     3061 aatgaagcgc aagggaacaa gtggtttgcc tggtgtccta cctgtcctga acctggtcct
     3121 gtgggccatt gaaaagttag atctgtgatc tctggggttt ttgtggcttt gttcaatgct
     3181 tccactctag ggcaggcaga gcagtctata ctctcccaag cctgcttgac ctccaagtag
     3241 agctgataca gagatctgtg aatattgtga tagaaattct ttggtattca tacatttcag
     3301 ctgcaagtca gcaatttccc aggtaccatg taagctataa aacagtcatt cttaaagaca
     3361 gaggatagct gtgactcatg ggatcatgag gtccatggct ggttgcaggt tccctttttc
     3421 cttcctcagg ttttgtctct tcctgtgttg tccccagcaa gggagagact gtggggtgga
     3481 ttgggagaac agattaggag tatagcaaat gaacccagaa tggaacagtg gggagctaac
     3541 tgtgaatgag gagagtacct gctgcaggac ctggaggtca ggtgtgaatg ctgtattggc
     3601 acagggaata aatatcctgg cgtctggagc cttcacctct ccgtcaagtc cttcctgtga
     3661 tactgccatg gcacaggatc tgagttgcag ctctgcaccc taaatcacac cctgggcatt
     3721 gtctgggctg cagggctgcc aggttctgta cttgtgtcca gctgtggccc tggatgctgg
     3781 agctggaggg ttttctgtgc tcagactgta gcctgtagct cttggcctgt gtagagcccc
     3841 ctcctgtgcc ctcagtggct gtcgtttgtt aacatcatca ggaagatggg aaaggtcagg
     3901 cagaattttt ctgccctaca aagggtggaa gagaaaggac acagtatttt catgaattta
     3961 ccatatatct ttgtttttct tcaacgaaaa agttaattga ggcaatgtca tctgctcaaa
     4021 gttgagtggt ttattcacaa taaactgtaa gtttctgatt ataaaaatgt gtctagagtc
     4081 tttcttcatg gggtctaggt agtcttctga gcccacaggg gtctggccag tgaacaccag
     4141 aggagtgcct tcctatcagt cagccccttc ttccagaggg ctgtggaggc cccagtggcc
     4201 aaactcggct ctgttttccc tttctggctg ttgggggaga gggcacctgt aagtgatccc
     4261 tgtggaatga agtagaaaat cctgccagtt ttccgctctc ctctccctca gtacaggctg
     4321 aatcattccc caccacagat agatcccagg gttgtggtag agtactgata taaatgtccc
     4381 aaccccccca ttctgagacc tccggacccc tccaaagcag acatgggaat gtagggctgt
     4441 ggaatatggc agggtgaact ccagcttcac gggagcccta agggttatga agagacaact
     4501 tggggcagaa acaagtgtgg agtctaatct caagggtgaa ggacaggaaa tgaggtttgg
     4561 attgattaag ggggtccaca tttgtggtgt cagaagtggc agtagtgtca gtgataagta
     4621 gctcaggggt agagtggagg ctccatagct gtgggcaaca tgcacagggc acctgtggct
     4681 agaagaggcc tcatacattg ccagtctgaa ctccgcagct cttcctctgg acctcaggtg
     4741 tgccaagccc cacgcttggc acctgggcat acagtggtat gcaagtgatt cacgtgctct
     4801 agcttccagg agcttccaat ccatggggaa catagaagga attgatcact agtgaatgtt
     4861 tgttttttgt tttgagacag tctcgctcta tcgcccagac tggagtac
//
