LOCUS       NM_001017363            1870 bp    mRNA    linear   PRI 08-FEB-2025
DEFINITION  Homo sapiens AT-rich interaction domain 3C (ARID3C), transcript
            variant 1, mRNA.
ACCESSION   NM_001017363 XM_071061
VERSION     NM_001017363.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1870)
  AUTHORS   Kim,H.S., Kim,Y.I. and Cho,J.Y.
  TITLE     ARID3C Acts as a Regulator of Monocyte-to-Macrophage
            Differentiation Interacting with NPM1
  JOURNAL   J Proteome Res 23 (8), 2882-2892 (2024)
   PUBMED   38231884
REFERENCE   2  (bases 1 to 1870)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 1870)
  AUTHORS   Tidwell,J.A., Schmidt,C., Heaton,P., Wilson,V. and Tucker,P.W.
  TITLE     Characterization of a new ARID family transcription factor
            (Brightlike/ARID3C) that co-activates Bright/ARID3A-mediated
            immunoglobulin gene transcription
  JOURNAL   Mol Immunol 49 (1-2), 260-272 (2011)
   PUBMED   21955986
  REMARK    GeneRIF: this report introduces Brightlike as an additional
            functional member of the family of ARID proteins, which should be
            considered in regulatory circuits, previously ascribed to be
            mediated by Bright.[ARID3C]
REFERENCE   4  (bases 1 to 1870)
  AUTHORS   Wilsker,D., Probst,L., Wain,H.M., Maltais,L., Tucker,P.W. and
            Moran,E.
  TITLE     Nomenclature of the ARID family of DNA-binding proteins
  JOURNAL   Genomics 86 (2), 242-251 (2005)
   PUBMED   15922553
REFERENCE   5  (bases 1 to 1870)
  AUTHORS   Wilsker,D., Patsialou,A., Dallas,P.B. and Moran,E.
  TITLE     ARID proteins: a diverse family of DNA binding proteins implicated
            in the control of cell growth, differentiation, and development
  JOURNAL   Cell Growth Differ 13 (3), 95-106 (2002)
   PUBMED   11959810
  REMARK    Review article
REFERENCE   6  (bases 1 to 1870)
  AUTHORS   Kortschak,R.D., Tucker,P.W. and Saint,R.
  TITLE     ARID proteins come in from the desert
  JOURNAL   Trends Biochem Sci 25 (6), 294-299 (2000)
   PUBMED   10838570
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL450283.16.
            
            On Mar 24, 2021 this sequence version replaced NM_001017363.3.
            
            Summary: This gene is a member of the ARID (AT-rich interaction
            domain) family of proteins. The ARID domain is a helix-turn-helix
            motif-based DNA-binding domain. ARID family members have roles in
            embryonic patterning, cell lineage gene regulation, cell cycle
            control, transcriptional regulation and possibly in chromatin
            structure modification. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000378909.4/ ENSP00000368189.2
            RefSeq Select criteria :: based on manual assertion, conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-150               AL450283.16        16455-16604         c
            151-540             AL450283.16        15235-15624         c
            541-613             AL450283.16        13280-13352         c
            614-797             AL450283.16        11402-11585         c
            798-1087            AL450283.16        10963-11252         c
            1088-1270           AL450283.16        9885-10067          c
            1271-1360           AL450283.16        9558-9647           c
            1361-1870           AL450283.16        8587-9096           c
FEATURES             Location/Qualifiers
     source          1..1870
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9p13.3"
     gene            1..1870
                     /gene="ARID3C"
                     /note="AT-rich interaction domain 3C"
                     /db_xref="GeneID:138715"
                     /db_xref="HGNC:HGNC:21209"
                     /db_xref="MIM:620868"
     exon            1..150
                     /gene="ARID3C"
                     /inference="alignment:Splign:2.1.0"
     exon            151..540
                     /gene="ARID3C"
                     /inference="alignment:Splign:2.1.0"
     CDS             223..1461
                     /gene="ARID3C"
                     /note="isoform 1 is encoded by transcript variant 1;
                     AT-rich interactive domain-containing protein 3C; ARID
                     domain-containing protein 3C; Brightlike; AT rich
                     interactive domain 3C (BRIGHT-like)"
                     /codon_start=1
                     /product="AT-rich interactive domain-containing protein 3C
                     isoform 1"
                     /protein_id="NP_001017363.1"
                     /db_xref="CCDS:CCDS35006.1"
                     /db_xref="GeneID:138715"
                     /db_xref="HGNC:HGNC:21209"
                     /db_xref="MIM:620868"
                     /translation="MEALQKQQAARLAQGVGPLAPACPLLPPQPPLPDHRTLQAPEGA
                     LGNVGAEEEEDAEEDEEKREEAGAEEEAAEESRPGAQGPSSPSSQPPGLHPHEWTYEE
                     QFKQLYELDADPKRKEFLDDLFSFMQKRGTPVNRVPIMAKQVLDLYALFRLVTAKGGL
                     VEVINRKVWREVTRGLSLPTTITSAAFTLRTQYMKYLYPYECETRALSSPGELQAAID
                     SNRREGRRQAYTATPLFGLAGPPPRGAQDPALGPGPAPPATQSSPGPAQGSTSGLPAH
                     ACAQLSPSPIKKEESGIPNPCLALPVGLALGPTREKLAPEEPPEKRAVLMGPMDPPRP
                     CMPPSFLPRGKVPLREERLDGPLNLAGSGISSINMALEINGVVYTGVLFARRQPVPAS
                     QGPTNPAPPPSTGPPSSILP"
     exon            541..613
                     /gene="ARID3C"
                     /inference="alignment:Splign:2.1.0"
     exon            614..797
                     /gene="ARID3C"
                     /inference="alignment:Splign:2.1.0"
     exon            798..1087
                     /gene="ARID3C"
                     /inference="alignment:Splign:2.1.0"
     exon            1088..1270
                     /gene="ARID3C"
                     /inference="alignment:Splign:2.1.0"
     exon            1271..1360
                     /gene="ARID3C"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1870
                     /gene="ARID3C"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1848..1853
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ARID3C"
                     /note="hexamer: AATAAA"
     polyA_site      1870
                     /gene="ARID3C"
                     /note="major polyA site"
ORIGIN      
        1 agcgcggcga gtgagcgcac agccgccaga ggagcacagg gcggcgggag cgcaccgccg
       61 ggacccagcc gaggccaggg ccgcctggga ggcgggcgga gcaaaggcag cgccgtggag
      121 acgccagggg cagcgggcca cgccaggcag gcggcccttt cctcggggtc ccgcctggta
      181 ccagggaccc cctcagctgg gggactgcgc ctggaagctg tcatggaggc cctgcagaag
      241 cagcaggcag ctcggctggc ccagggggtg gggccattgg cccctgcatg cccgctgctg
      301 ccaccgcagc ctcccctgcc tgaccaccgg accctacagg cccctgaggg ggccttgggg
      361 aatgttgggg ctgaggaaga ggaagatgct gaagaagatg aggagaagcg ggaggaagcc
      421 ggggcagagg aggaggcagc tgaggagagc cgtccagggg cccagggccc cagctcgcct
      481 tctagccagc cccctggact ccatccccac gagtggacct acgaggaaca attcaagcag
      541 ctgtatgagc tcgatgcaga ccccaagagg aaggaatttc tggatgacct gtttagcttc
      601 atgcaaaaga gggggacgcc agtgaaccgc gtgcccatca tggcgaagca ggtgctcgac
      661 ctgtacgctc tgtttcgcct ggtgaccgcc aagggcggcc tggtggaagt catcaaccgc
      721 aaagtgtggc gggaagtcac gcgcggcctc agcctaccca ccaccatcac ctcggccgcc
      781 ttcactctac gcacccagta catgaagtac ctgtacccgt acgagtgcga gactcgagcg
      841 ctcagctccc caggggagct ccaggccgcc atagacagca atcggcgcga gggccgtcgc
      901 caggcttaca ccgctactcc gctcttcggc ttggcagggc cgccccctcg gggcgctcag
      961 gacccagcct tgggtcccgg ccccgcccct ccggcgaccc agtccagccc tggcccagcc
     1021 cagggttcca cctccggcct gccagcgcat gcatgcgctc agctgagtcc aagccctatt
     1081 aagaaagagg agagtggaat tccaaaccct tgtctggcac tgcctgtggg cctggcactg
     1141 ggacctacac gggagaaatt ggcaccagag gagcccccag agaagagagc tgtgctgatg
     1201 gggcctatgg acccacctcg accttgcatg ccccccagtt tcctgccccg tggcaaggtt
     1261 cccctgaggg aagagcggct ggatgggcct cttaatctgg caggcagtgg catcagcagt
     1321 atcaacatgg ccctagagat caacggggtg gtctacactg gtgtcctctt tgcccgccgc
     1381 cagcctgtgc cagcttccca gggtccaacc aaccctgcac ccccaccctc cacagggccc
     1441 ccttccagca tcttgccctg agaggtccta cttgaaacta agagtcccag ccccattgct
     1501 gaggggggag gagaccccct gctttgattc tttctggctg cccactctgg gacccagccc
     1561 tgggagggga cgacacctcc catgccatgt ggacttaaaa ccaaagtttc ttttgatgtt
     1621 acacctacct cattgtaaag ggagggcacc tcctccctgg ccaattccag cagcacctac
     1681 caaagggttc ttcctccagt aaccccatca tctcctcatg tgttccctct gtcaatgtca
     1741 tctctaggac cctacccttt tgagtcagcc ctgcttctct tcaggagcca agtgaaaggt
     1801 tgggttgggg tactgtgaaa gagacatccc tcaggtcaca tctagacaat aaagctgcgg
     1861 tccctccctc
//
