LOCUS       NM_014783               5876 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens Rho GTPase activating protein 11A (ARHGAP11A),
            transcript variant 1, mRNA.
ACCESSION   NM_014783 XM_350973
VERSION     NM_014783.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5876)
  AUTHORS   Bagci,H., Winkler,M., Gradel,B., Uliana,F., Boulais,J.,
            Mohamed,W.I., Park,S.L., Cote,J.F., Pertz,O. and Peter,M.
  TITLE     The hGIDGID4 E3 ubiquitin ligase complex targets ARHGAP11A to
            regulate cell migration
  JOURNAL   Life Sci Alliance 7 (12), e202403046 (2024)
   PUBMED   39389782
  REMARK    GeneRIF: The hGID[GID4] E3 ubiquitin ligase complex targets
            ARHGAP11A to regulate cell migration.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5876)
  AUTHORS   Naeimzadeh,Y., Ilbeigi,S., Dastsooz,H., Rafiee Monjezi,M.,
            Mansoori,Y. and Tabei,S.M.B.
  TITLE     Protooncogenic Role of ARHGAP11A and ARHGAP11B in Invasive Ductal
            Carcinoma: Two Promising Breast Cancer Biomarkers
  JOURNAL   Biomed Res Int 2023, 8236853 (2023)
   PUBMED   38046902
  REMARK    GeneRIF: Protooncogenic Role of ARHGAP11A and ARHGAP11B in Invasive
            Ductal Carcinoma: Two Promising Breast Cancer Biomarkers.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5876)
  AUTHORS   Yang,H., Zhang,H., Zhang,L., Tusuphan,P. and Zheng,J.
  TITLE     ARHGAP11A Is a Novel Prognostic and Predictive Biomarker Correlated
            with Immunosuppressive Microenvironment in Clear Cell Renal Cell
            Carcinoma
  JOURNAL   Int J Mol Sci 24 (9), 7755 (2023)
   PUBMED   37175461
  REMARK    GeneRIF: ARHGAP11A Is a Novel Prognostic and Predictive Biomarker
            Correlated with Immunosuppressive Microenvironment in Clear Cell
            Renal Cell Carcinoma.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5876)
  AUTHORS   Pilaz,L.J., Liu,J., Joshi,K., Tsunekawa,Y., Musso,C.M.,
            D'Arcy,B.R., Suzuki,I.K., Alsina,F.C., Kc,P., Sethi,S.,
            Vanderhaeghen,P., Polleux,F. and Silver,D.L.
  TITLE     Subcellular mRNA localization and local translation of Arhgap11a in
            radial glial progenitors regulates cortical development
  JOURNAL   Neuron 111 (6), 839-856 (2023)
   PUBMED   36924763
  REMARK    GeneRIF: Subcellular mRNA localization and local translation of
            Arhgap11a in radial glial progenitors regulates cortical
            development.
REFERENCE   5  (bases 1 to 5876)
  AUTHORS   Zheng,L., Cai,X., Song,J., Shi,H., Zhang,J., Ke,X., Li,H. and
            Chen,Y.
  TITLE     MicroRNA-30c-2-3p represses malignant progression of gastric
            adenocarcinoma cells via targeting ARHGAP11A
  JOURNAL   Bioengineered 13 (6), 14534-14544 (2022)
   PUBMED   35754342
  REMARK    GeneRIF: MicroRNA-30c-2-3p represses malignant progression of
            gastric adenocarcinoma cells via targeting ARHGAP11A.
REFERENCE   6  (bases 1 to 5876)
  AUTHORS   Fu,A., Jacobs,D.I., Hoffman,A.E., Zheng,T. and Zhu,Y.
  TITLE     PIWI-interacting RNA 021285 is involved in breast tumorigenesis
            possibly by remodeling the cancer epigenome
  JOURNAL   Carcinogenesis 36 (10), 1094-1102 (2015)
   PUBMED   26210741
REFERENCE   7  (bases 1 to 5876)
  AUTHORS   Kagawa,Y., Matsumoto,S., Kamioka,Y., Mimori,K., Naito,Y., Ishii,T.,
            Okuzaki,D., Nishida,N., Maeda,S., Naito,A., Kikuta,J.,
            Nishikawa,K., Nishimura,J., Haraguchi,N., Takemasa,I.,
            Mizushima,T., Ikeda,M., Yamamoto,H., Sekimoto,M., Ishii,H.,
            Doki,Y., Matsuda,M., Kikuchi,A., Mori,M. and Ishii,M.
  TITLE     Cell cycle-dependent Rho GTPase activity dynamically regulates
            cancer cell motility and invasion in vivo
  JOURNAL   PLoS One 8 (12), e83629 (2013)
   PUBMED   24386239
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 5876)
  AUTHORS   Xu,J., Zhou,X., Wang,J., Li,Z., Kong,X., Qian,J., Hu,Y. and
            Fang,J.Y.
  TITLE     RhoGAPs attenuate cell proliferation by direct interaction with p53
            tetramerization domain
  JOURNAL   Cell Rep 3 (5), 1526-1538 (2013)
   PUBMED   23684608
REFERENCE   9  (bases 1 to 5876)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS One 7 (12), e51954 (2012)
   PUBMED   23251661
REFERENCE   10 (bases 1 to 5876)
  AUTHORS   Riley,B., Williamson,M., Collier,D., Wilkie,H. and Makoff,A.
  TITLE     A 3-Mb map of a large Segmental duplication overlapping the
            alpha7-nicotinic acetylcholine receptor gene (CHRNA7) at human
            15q13-q14
  JOURNAL   Genomics 79 (2), 197-209 (2002)
   PUBMED   11829490
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from D87717.2 and AC123768.8.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_014783.5.
            
            Summary: This gene encodes a member of the Rho GTPase activating
            protein family. In response to DNA damage, the encoded protein
            interacts with the p53 tumor suppressor protein and stimulates its
            tetramerization, which results in cell-cycle arrest and apoptosis.
            A chromosomal deletion that includes this gene is one cause of
            Prader-Willi syndrome, and an intronic variant of this gene may be
            associated with sleep duration in children. This gene is highly
            expressed in colon cancers and in a human basal-like breast cancer
            cell line. This gene also produces a ARHGAP11A-SCG5 readthrough
            transcript and ARHGAP11A-SCG5 protein. [provided by RefSeq, Feb
            2019].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D87717.2, SRR1803614.134722.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000361627.8/ ENSP00000355090.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4238              D87717.2           15-4252
            4239-4239           AC123768.8         126543-126543
            4240-5602           D87717.2           4254-5616
            5603-5876           AC123768.8         127907-128180
FEATURES             Location/Qualifiers
     source          1..5876
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q13.3"
     gene            1..5876
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /note="Rho GTPase activating protein 11A"
                     /db_xref="GeneID:9824"
                     /db_xref="HGNC:HGNC:15783"
                     /db_xref="MIM:610589"
     exon            1..837
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /inference="alignment:Splign:2.1.0"
     CDS             709..3780
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /note="isoform 1 is encoded by transcript variant 1;
                     rho-type GTPase-activating protein 11A"
                     /codon_start=1
                     /product="rho GTPase-activating protein 11A isoform 1"
                     /protein_id="NP_055598.1"
                     /db_xref="CCDS:CCDS10028.1"
                     /db_xref="GeneID:9824"
                     /db_xref="HGNC:HGNC:15783"
                     /db_xref="MIM:610589"
                     /translation="MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGG
                     KIFGVPFNALPHSAVPEYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKV
                     DHGEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLS
                     CLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTE
                     KKLRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPG
                     EYKRKRRQSVGDFVSGALNKFKPNRTPSITPQEERIAQLSESPVILTPNAKRTLPVDS
                     SHGFSSKKRKSIKHNFNFELLPSNLFNSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNH
                     LITAGVPRRSKRIAGKKVCRVESGKAGCFSPKISHKEKVRRSLRLKFNLGKNGREVNG
                     CSGVNRYESVGWRLANQQSLKNRIESVKTGLLFSPDVDEKLPKKGSEKISKSEETLLT
                     PERLVGTNYRMSWTGPNNSSFQEVDANEASSMVENLEVENSLEPDIMVEKSPATSCEL
                     TPSNLNNKHNSNITSSPLSGDENNMTKETLVKVQKAFSESGSNLHALMNQRQSSVTNV
                     GKVKLTEPSYLEDSPEENLFETNDLTIVESKEKYEHHTGKGEKCFSERDFSPLQTQTF
                     NRETTIKCYSTQMKMEHEKDIHSNMPKDYLSKQEFSSDEEIKKQQSPKDKLNNKLKEN
                     ENMMEGNLPKCAAHSKDEARSSFSQQSTCVVTNLSKPRPMRIAKQQSLETCEKTVSES
                     SQMTEHRKVSDHIQWFNKLSLNEPNRIKVKSPLKFQRTPVRQSVRRINSLLEYSRQPT
                     GHKLASLGDTASPLVKSVSCDGALSSCIESASKDSSVSCIKSGPKEQKSMSCEESNIG
                     AISKSSMELPSKSFLKMRKHPDSVNASLRSTTVYKQKILSDGQVKVPLDDLTNHDIVK
                     PVVNNNMGISSGINNRVLRRPSERGRAWYKGSPKHPIGKTQLLPTSKPVDL"
     exon            838..908
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /inference="alignment:Splign:2.1.0"
     exon            909..1005
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1259
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /inference="alignment:Splign:2.1.0"
     exon            1260..1423
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..1570
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..1645
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1813
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /inference="alignment:Splign:2.1.0"
     exon            1814..1943
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /inference="alignment:Splign:2.1.0"
     exon            1944..2052
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /inference="alignment:Splign:2.1.0"
     exon            2053..2191
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /inference="alignment:Splign:2.1.0"
     exon            2192..5876
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4955..4960
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /note="hexamer: ATTAAA"
     polyA_site      4980
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /note="major polyA site"
     regulatory      5574..5579
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /note="hexamer: AATGAA"
     polyA_site      5600
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
     regulatory      5858..5863
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
                     /note="hexamer: AATAAA"
     polyA_site      5876
                     /gene="ARHGAP11A"
                     /gene_synonym="GAP (1-12)"
ORIGIN      
        1 gacccccccg tggtggctct gggtgtctgc ggaggagctg ggggcggaag catgaggcta
       61 acggcttggc ttcagtgaac gcaccgggat gtgcaggccg ggaggtagag gcaggctgat
      121 gggggaggga acgagcagcc tgtgagacgg ggtgacggcg gctaccagcc cgggcgggca
      181 ccgggactgg aagagttgcc tgagcagccg gctggtccgg cggccaggct agggcggggg
      241 cgagcgccca gttgagcctg ctggggctgg aggagcgaga agggttttct tcacatttca
      301 gagcgaacca gacggggaca gtaaggtttg gaggaagggg gatcgttgga agtagcaaga
      361 agtggagaga atctggcaat agacgagaaa ccgaaagaat cagaaagaag tctatgtgag
      421 tagctgaaag cattgggtga ccagaaagaa ggtcggtgta agtgaaggaa gagtgaggtg
      481 tggctggatc aaagggctaa gagaagcggg tctgtgtaag tggatgtgag tgaggatcaa
      541 ggaaaagccg tggaagtggc cgggggtcgg ggccgcagaa gtgccagacg gggccggaaa
      601 gcagccgagc ggagttcaaa tttgagagcg tttggaaatt ggaagacttg gtggcgaacg
      661 agggtcagga cctgcatcct gcctcagaga gttatcgacg tatccggaat gtgggatcag
      721 aggctggtga ggttggccct gttgcagcat ctgcgggcct tctatggtat taaggtgaag
      781 ggtgtccgtg ggcagtgcga tcgcaggaga catgaaacag cagccacgga aatagggggt
      841 aaaatatttg gagtaccttt taatgcactg ccccattctg ctgtaccaga atatggacac
      901 attccaagct ttcttgtcga tgcttgcaca tctttagaag accatattca taccgaaggg
      961 ctttttcgga aatcaggatc tgtgattcgc ctaaaagcac taaagaataa agtggatcat
     1021 ggtgaaggtt gcctatcttc tgcacctcct tgtgatattg cgggacttct taagcagttt
     1081 tttagggaac tgccagagcc cattctccca gctgatttgc atgaagcact tttgaaagct
     1141 caacagttag gcacagagga aaagaataaa gctacactgt tgctctcctg tcttctggct
     1201 gaccacacag ttcatgtatt aagatacttc tttaactttc tcaggaatgt ttctcttaga
     1261 tccagtgaga ataagatgga cagcagcaat cttgcagtaa tatttgcacc gaatcttctt
     1321 cagacaagtg aaggacatga aaagatgtct tctaacacag aaaagaagct acgattacag
     1381 gctgcagtag tacagactct tatcgattat gcatcagata ttgggcgtgt accagatttt
     1441 atcctggaaa agataccagc catgttgggt attgatggtc tctgtgctac tccatcactg
     1501 gaaggctttg aagaaggtga atatgaaact cctggtgaat ataagagaaa gagaagacaa
     1561 agtgtaggag attttgttag tggagcacta aataaattta aacctaacag aacaccttct
     1621 attacacctc aagaagaaag aattgcccag ctatctgaat caccagtgat tcttacacca
     1681 aatgctaagc gtacattgcc agtagattct tctcatggtt tctcaagtaa gaaaaggaag
     1741 tccatcaagc acaattttaa ctttgagctg ttgccaagta atctcttcaa tagcagttct
     1801 acaccggtat cagttcacat cgatacaagc tcagaagggt catctcagag ttcactctct
     1861 cctgtactca ttggtggaaa ccatttgatc actgcaggtg tgccaaggcg aagtaaaaga
     1921 attgcaggca aaaaagtttg cagagtggaa tcaggaaaag caggctgctt ttctcctaaa
     1981 atcagccata aagaaaaggt tcgaagatct ctgcgtttga aattcaatct agggaaaaat
     2041 ggcagagaag taaatggatg ttctggtgtc aatagatatg aaagtgttgg ttggcgactt
     2101 gcaaatcaac aaagtttaaa aaatcgaatt gaatctgtaa aaacaggttt gctttttagc
     2161 ccagatgttg atgaaaagtt accaaagaaa ggttcagaaa agatcagtaa gtctgaggaa
     2221 accttactaa ctccagagcg actagttgga acaaattacc ggatgtcttg gacaggacct
     2281 aataattcaa gttttcaaga agtagatgca aatgaagctt cttcaatggt ggaaaatctt
     2341 gaggtagaaa actctttgga gcctgatatt atggtagaaa agtcacctgc tacttcatgt
     2401 gaactcaccc cttccaattt aaacaataag cataatagca acataacaag tagccctctt
     2461 agcggggatg aaaataacat gaccaaagag actttggtga aagttcaaaa agcgttttct
     2521 gaatctggaa gtaatcttca cgcattgatg aatcagaggc agtcatcagt aactaatgtg
     2581 gggaaagtaa aattaactga accatcttat ttagaagata gcccagagga aaatctattt
     2641 gaaactaatg atttgactat agtagaatca aaggagaaat atgaacacca cactggtaaa
     2701 ggtgaaaaat gtttttcaga gagggacttt tcaccccttc aaactcaaac atttaataga
     2761 gaaacaacta taaaatgtta ttcaactcag atgaagatgg aacatgaaaa agacattcat
     2821 tcaaatatgc caaaagatta tttaagcaag caagaattct ccagtgatga agaaataaag
     2881 aaacagcagt ccccaaagga taaactaaat aataaattaa aagagaatga gaatatgatg
     2941 gaaggtaact taccgaagtg tgcagcacat agcaaggacg aggctagatc ctctttctca
     3001 cagcagagta catgtgttgt aacaaacttg tcaaaaccta ggcctatgag aattgctaaa
     3061 cagcagtcat tggaaacatg tgagaaaaca gtttctgaaa gttcacaaat gacagaacat
     3121 agaaaggttt ctgatcacat acagtggttt aacaagcttt ctttaaatga accaaataga
     3181 ataaaagtca agtcacctct taagtttcag cgtactcctg ttcgtcagtc cgtcagaaga
     3241 attaattctt tgttggagta tagcagacaa cctacagggc ataagttggc gagtcttggt
     3301 gatacagctt ctcctttggt caaatcagtg agctgtgacg gtgctctttc ctcttgtata
     3361 gaaagtgcat caaaagattc ctctgtttca tgtatcaaat caggtcctaa agaacagaag
     3421 tccatgtcat gtgaagagtc aaatattggt gcaatttcaa agtcaagcat ggagttaccc
     3481 tcgaaatctt tcttaaagat gaggaagcac ccagattcag tgaatgcttc tcttaggtct
     3541 actacagttt ataaacagaa gatcttatct gatggccaag ttaaggttcc cttggatgat
     3601 ctgactaatc atgatatagt aaaaccagtt gtaaataaca acatgggcat ttcttctggg
     3661 ataaataaca gggtccttag gagaccatca gaaagaggaa gggcctggta caaaggttct
     3721 ccaaaacatc ctatcggaaa aactcaatta ctaccaacaa gtaaacctgt agatttgtaa
     3781 ttggtaaatg ttatacttgt cattaatgta aataaagtga gtaattggta tgacttgcag
     3841 gatgatgtac atgttagttt gtagctcagg atgattgtta agcaatagat ttgctctatt
     3901 gaaaatgttt catttttttc actgtacaag caacttagat ttttatttgt acaaattact
     3961 tctttgtttt tcttaatgat ggcaattttt aaactttaat tttattgtga tctcttaaag
     4021 cagaggttag actttacctt tctgactctg tcgtccaggc tggagtgcag tggcgcaatc
     4081 tcactgcaag ctccacttcc tgggttcatg ccattttcct gcctcagcct cccgagtagc
     4141 tgggactaca ggtgcccgcc accacgccca gctaattttt tgtattttta gtagagacgg
     4201 tttcaccgtg ttagccagga tggtctcgat ctcctgacgt tgtgatccgc ccgcctcagc
     4261 ctcccaaagt gctgggatta caggcatgag ccaccacgcc cggctagact ttacctttct
     4321 aaagaaattg tttactggat ttataagaag ttaatttttg aaaatgacat atttttgtgt
     4381 gatagaaaga atggagcaag ttgtgcctat ttcctccaag tcagataagg tttctaaaat
     4441 aaataaattt ctagcatata aagggtagag ataaactctg caaatcttat gtctggaatt
     4501 atattaatgt ttattgtcct tgccaaaatt cctagaaatt aatttccttc aatagcatcc
     4561 taaaactcta tttttatttg gggcagagta atttcattta tagtgccagt aggtgtacct
     4621 tgtgttcact cgaactaaga acaatggtta aggcagaata atgactaaaa tatgttcata
     4681 tattatgatg tggaaataat tgataacttt taagccatac tatgttttta aagataattt
     4741 gcacaaacac gtttgtgtct gttctgtcca atatagattt ggcaattatt taaagaggga
     4801 taatcttgaa aaaaattaac caaggtgatt tcttatatgt agatgctcga ttttggaatt
     4861 tgaaatagta gatgcacctc tttacctttt ttacttggat aaaaacctat gatgattttg
     4921 tcctgtgtgt aaatgttatt tatttagcat agacattaaa gataactctc tggaaaatga
     4981 cttgactaag gctctcatga aattcaaagt gccatttaga acatgcacca aattgtcaag
     5041 taaatctgtc taaatttata ttttaaatta ttacaaatta cacatctttg aggaaagagt
     5101 attatgaaca atagaacata ttctctaggt tgtagaggaa ggaataagca gacagaatca
     5161 accactaaag gtagtttttc agattggttg ttagaatgtc atgtttagat gttggagcag
     5221 attagagcag cattcatgcc actcggagca accagactta cagcataagt atgtacgagg
     5281 aatttcaaat catcagatgt ttgcttggct aggttctact ttgtttattt gatatcaaat
     5341 aggtttgtag atgtttatgg catttctaat tgtaagtaga gacaaaatat tcatatagtc
     5401 agatatatgt tgtctgcttt aaacaatttt taaattttaa aaatgcatta acgtcttttt
     5461 atatccatca agggaaggat gaaatgttga atttgaagac taattcagta agaagtccta
     5521 ggggtttaac tgtacatact acctgaactg gcttttctga gagatgaatc aataatgaaa
     5581 catgtctgtt ttaaaaacta ccacatgtga ctcctatttt tgttagctga aagctgctat
     5641 acggagtatt acaggaatgt gaaggtgact agcttgaagg tagggtaact agagagccag
     5701 aaaagttttg ttttaaactt gatttaatgc gtttttattt tttcttatac aaaatagaga
     5761 taatgttgct aacttcatgg aatatttgag gaaatgatat gaaagtgtct ggacgtgcag
     5821 taacctcatg ggttcttctc actgtcttat aaatgtaaat aaagatctaa tattaa
//
