LOCUS       NM_001382497            1220 bp    mRNA    linear   PRI 01-DEC-2024
DEFINITION  Homo sapiens aquaporin 7B (AQP7B), mRNA.
ACCESSION   NM_001382497
VERSION     NM_001382497.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1220)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL845331.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2153980
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000561882.2/ ENSP00000456868.2
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-99                AL845331.2         24887-24985
            100-150             AL845331.2         26073-26123
            151-280             AL845331.2         32320-32449
            281-404             AL845331.2         40068-40191
            405-542             AL845331.2         40613-40750
            543-661             AL845331.2         40959-41077
            662-879             AL845331.2         41288-41505
            880-1220            AL845331.2         41864-42204
FEATURES             Location/Qualifiers
     source          1..1220
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q11.1"
     gene            1..1220
                     /gene="AQP7B"
                     /note="aquaporin 7B"
                     /db_xref="GeneID:100509620"
                     /db_xref="HGNC:HGNC:53895"
     exon            1..99
                     /gene="AQP7B"
                     /inference="alignment:Splign:2.1.0"
     exon            100..150
                     /gene="AQP7B"
                     /inference="alignment:Splign:2.1.0"
     CDS             125..1165
                     /gene="AQP7B"
                     /codon_start=1
                     /product="putative aquaporin-7B"
                     /protein_id="NP_001369426.1"
                     /db_xref="CCDS:CCDS92802.1"
                     /db_xref="GeneID:100509620"
                     /db_xref="HGNC:HGNC:53895"
                     /translation="MVQASGHRRSTRGSKMVSWSVIAKIQEIWCEEDERKMVREFLAE
                     FMSTYVMMVFGLGSVAHMVLNKTYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVT
                     FTNCALGRVPWRKFPVHVLGQFLGSFLAAATIYSLFYTAILHFSGGELMVTGPFATAG
                     IFATYLPDHMTLWRGFLNEEWLTRMLQLCLFTITDQENNPALPGTHALVISILVVIIR
                     VSHGINTGYAINPSRDPPPSIFTFIAGWGKQVFSDGENWWWVPVVAPLLGASLGGIIY
                     LVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPMISPLTLISVSLANRSSVHSA
                     PPLHESMALEHF"
     exon            151..280
                     /gene="AQP7B"
                     /inference="alignment:Splign:2.1.0"
     exon            281..404
                     /gene="AQP7B"
                     /inference="alignment:Splign:2.1.0"
     exon            405..542
                     /gene="AQP7B"
                     /inference="alignment:Splign:2.1.0"
     exon            543..661
                     /gene="AQP7B"
                     /inference="alignment:Splign:2.1.0"
     exon            662..879
                     /gene="AQP7B"
                     /inference="alignment:Splign:2.1.0"
     exon            880..1220
                     /gene="AQP7B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1198..1203
                     /regulatory_class="polyA_signal_sequence"
                     /gene="AQP7B"
                     /note="hexamer: AATAAA"
     polyA_site      1220
                     /gene="AQP7B"
                     /note="major polyA site"
ORIGIN      
        1 agctgagcca gggacagtca cggaggaaga agatcaagat gcgctttaac tgagaagccc
       61 ccaaggcaga ggctgagaat cagaagacat ttcaggagac atctacaaat ctgaaggaca
      121 aaacatggtt caagcatctg ggcacaggcg gtccacccgt ggctccaaaa tggtctcctg
      181 gtccgtgata gcaaagatcc aggaaatatg gtgcgaggaa gatgagagga agatggtgcg
      241 agagttcttg gccgagttca tgagcacata tgtcatgatg gtattcggcc ttggttctgt
      301 ggcccatatg gttctaaata aaacatatgg gagctacctt ggtgtcaact tgggttttgg
      361 cttcggggtc accatgggag tccacgtggc aggccgcatc tctggagccc acatgaatgc
      421 agctgtgacc ttcactaact gtgcgctggg ccgcgtgccc tggaggaagt ttccagtcca
      481 tgtgctgggg cagttcctgg gctccttcct ggcagctgcc accatctaca gtctcttcta
      541 cacggccatt ctccactttt cgggtggaga gctgatggtg accggtccct ttgctacagc
      601 tggcattttt gccacctacc ttcctgatca catgacattg tggcggggct tcctgaatga
      661 ggagtggctg accaggatgc tccagctgtg tctcttcacc atcacggacc aggagaacaa
      721 cccagcactg ccaggaacac acgcgctggt gataagcatc ctcgtggtca tcatcagggt
      781 gtcccatggc ataaacacag gatatgccat caatccatcc cgggacccgc cccccagcat
      841 cttcaccttc attgctggct ggggcaaaca ggtcttcagc gatggggaga actggtggtg
      901 ggtgccagtg gtggcaccac ttctgggtgc ctctctaggt ggcatcatct acctggtctt
      961 cattggctcc accatcccac gggagcccct gaaattggag gactctgtgg cgtatgaaga
     1021 ccacgggata accgtattgc ccaagatggg atctcatgaa cccatgatct ctcccctcac
     1081 cctcatctcc gtgagccttg ccaacagatc ttcagtccac tctgccccac ccttacatga
     1141 atccatggcc ctagagcact tctaagcaga gattatttgt gatcccatcc cttccccaat
     1201 aaagcaaagc ttgtcccaca
//
