LOCUS       XM_047435116            6203 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens amyloid beta precursor protein binding
            protein 2 (APPBP2), transcript variant X1, mRNA.
ACCESSION   XM_047435116
VERSION     XM_047435116.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6203
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..6203
                     /gene="APPBP2"
                     /gene_synonym="APP-BP2; HS.84084; PAT1"
                     /note="amyloid beta precursor protein binding protein 2;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 40 ESTs, 1667 long SRA reads, 1 Protein,
                     and 98% coverage of the annotated genomic feature by
                     RNAseq alignments, including 14 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:10513"
                     /db_xref="HGNC:HGNC:622"
                     /db_xref="MIM:605324"
     CDS             155..1780
                     /gene="APPBP2"
                     /gene_synonym="APP-BP2; HS.84084; PAT1"
                     /codon_start=1
                     /product="amyloid protein-binding protein 2 isoform X1"
                     /protein_id="XP_047291072.1"
                     /db_xref="GeneID:10513"
                     /db_xref="HGNC:HGNC:622"
                     /db_xref="MIM:605324"
                     /translation="MQLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMD
                     HGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSC
                     LQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQAN
                     KAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREF
                     KKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQS
                     VFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASS
                     KRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLG
                     RLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKL
                     YLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYS
                     VTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC"
ORIGIN      
        1 agatggggtt tcaccatgct ggccaagttt gtcttgaact cctgaccttg tgatccacct
       61 gcctcagcct cccaaagtgc tgggattaca gccatgagcc accactcctg gactcaaatg
      121 tgtatatttt tatagtttgc ttgtttggat caggatgcag ctttaccaac agggacgctt
      181 atgtcaactg ggcagtgaat tttgtgaatt ggaagttttt gctaaagtac tgagagcttt
      241 ggataaaaga catttgcttc atcattgttt tcaggctttg atggatcatg gtgttaaagt
      301 tgcttcagtc ttggcctact cattcagtag gcggtgctct tatatagcag aatcagatgc
      361 tgcagtaaag gaaaaagcca ttcaggttgg ctttgtttta ggtggctttc tttcagatgc
      421 aggctggtac agtgatgctg agaaagtttt tctgtcctgc cttcagttgt gtactctaca
      481 cgatgagatg cttcattggt ttcgtgcagt agaatgttgt gtgaggttgc ttcatgtgcg
      541 aaatggaaac tgcaaatatc atttgggtga agaaacattt aaattagctc agacatatat
      601 ggataaacta tcaaaacatg gccagcaagc aaataaagct gcactctatg gagaactgtg
      661 tgcactccta tttgcaaaaa gtcactatga tgaggcatac aaatggtgca tcgaggcaat
      721 gaaagaaatt acagcaggct taccagtgaa agttgtggtg gatgtcttaa gacaagcttc
      781 taaggcttgt gtagtaaaac gtgaatttaa gaaggcagaa cagttaatta aacatgcagt
      841 gtatttggca cgggatcatt ttggatccaa acacccaaaa tattctgata cactgctaga
      901 ttatgggttc tacttactca atgtagataa tatctgtcag tctgttgcaa tttatcaggc
      961 agcccttgac attagacagt cagtgtttgg tggcaaaaat atccacgtag caacagctca
     1021 tgaagatttg gcctactctt cttatgtcca ccagtatagc tctgggaaat ttgacaatgc
     1081 actatttcat gcagaaagag ctattggtat cattacccac atcctacctg aagatcatct
     1141 tcttttggct tcttcaaaga gggtgaaagc acttatttta gaggagattg caattgattg
     1201 tcataataag gaaactgaac agaggctgct tcaagaagct catgatttgc acctgtcttc
     1261 actccaacta gctaaaaaag cttttgggga atttaatgta cagactgcaa aacactatgg
     1321 aaaccttgga agactttatc agtcaatgag aaaatttaag gaagctgaag aaatgcacat
     1381 caaagcaatt cagattaaag aacaacttct tggtcaagaa gattatgaag tagccctttc
     1441 agtgggacat ctggcttctt tatataatta tgacatgaat cagtatgaaa atgctgagaa
     1501 actttatttg cgatctatag caattgggaa gaaacttttt ggtgagggct acagtggact
     1561 agaatatgat tatcgaggtc tcattaaact ttacaactcc attggaaatt acgagaaagt
     1621 gtttgaatat cacaatgttc tgtctaactg gaaccggttg cgagatcggc aatattcagt
     1681 gacagatgct cttgaagatg tcagcaccag cccccagtcc actgaagaag tggtgcagtc
     1741 cttcctgatt tctcagaatg tcgagggacc gagctgctga gggaggacct cagttaacca
     1801 attacctttt cccggattcc agggaattca tactgtgaaa tcaaaaccat gttgttttgg
     1861 ggggctggaa tttgcattga aacactggtc cagtccattg aagaccctat tttgggtgat
     1921 ccctatcttg cagaatgtct gtaggaataa gcatatattc agttatattc agcatgtacc
     1981 gcatgtgtaa gtagtctggc ccacattttc aacctagtag aacaaacaac aggaaatctt
     2041 ttttttgttg tttttaaaaa attcattttg cagaaagcct gaaagaaaaa aaatacccct
     2101 aaataaaact atttaagagt ttaaaagagt tgcattctta ttatgtaagg atgattttaa
     2161 caacttttta atatgtaatt cttccatgtg gaggtattca atactgtagt gtaaagaaat
     2221 tttatgcgga aaatctttat atgcagtata gaaaagttaa cacaagtact aataaaagag
     2281 ggacatcccg acttacgttt ttctaccttg cccagataag tggatacaac cactctatat
     2341 tacaaggaaa ggactgtcag attcatctga actggaccag tgttgatctg taatgtaata
     2401 gaaaatctga tagaccagca cttctgactt tttttttttt ggtacaacaa tgcaagatgc
     2461 tctgatagca tttgctaaca ggaccaggag gatctaaaaa ggaccagcct aatgtagaag
     2521 gtggttactt ggaccagagg ctttagatta ttattttaga tcctacatat acttttatca
     2581 gtagaatgat ttcatttaga tgtataatga aaaaggataa tgcaaaaatt atgtaataga
     2641 taccaaatta gggaagtttg gcaatttcaa tggcatattt ttagtcaagg tacacagatg
     2701 gcagtgccat aagcaagtct ataaatatcg gctgcagcca tccccctcat tttaaatgtt
     2761 gccctaataa tcaatgcagt taacaagtat attggctgtg tgtcatgaaa tagttcatgt
     2821 tcagatggaa atgttaggtt actgtatggt ttatggagat taatgaaaat gaatgcccaa
     2881 aaataagtct tagaaaatcc tccattttta tggtaaatag taatacaact aggtcatttc
     2941 atttgaaatc taggagtcaa atggaaagat cccctaataa tacacctatt tcactaactt
     3001 gtctttctgt ttattgggtt ttgatttgat tttttgtaag ccagtcaggt tatttaatga
     3061 tgaggtaata atcaaattta agaatttgtg acatgtagca attcaagaaa caaaaaggta
     3121 ttttgctgtt acctcaattc ttactgtagt agcccatctg atgcttctat agttaagaat
     3181 ctgggttccc cccctatttt caggggttca tgacttggct gttaaagatg ttgctcctag
     3241 ctaatgcttg gagtagtctg tgggtgaatg gatgtgtgtt gaattttagt tttcttttaa
     3301 catgcatgtt gggtgagagg ggaaaaaaat ctaagctgtc tgccacattg agtacagaaa
     3361 agttgtagat ttcaaatttt attaatattt taagcacttt tttgaacttc ccaaccttgt
     3421 ttgaagctgt tatttgcagt cctattagtt ttgagccatt gcatttaagt tccctaggag
     3481 ggggttggtt gggggatgta ctgaaagaga tgaagcaaac ccacacccta agatggtaac
     3541 tgtgtgattt agaaacctga gtttactcct caaatcgaat tattttcttt ttaaattttg
     3601 gaaagagtaa attgacgtac ttgcagttta tgaagctgcc ccccacccct cagttaattg
     3661 cagtctaatg tcaagaggca cttctttatt aattaccaaa tagtctttgt gaccaaggac
     3721 taacattttt aagttactca gctctatcct catgggccta tatatttaat acctccaaag
     3781 atattttcag gataggcttt gtatactttt attggttatt tagaatccag tggtatgttt
     3841 gtggtatagg aatgtcatgg taaattgttt ttcaataaat attttgaaac atgtttccat
     3901 atgaagtttt tttttcaatc tgtatttttt ggttttgtgc acatacagca tttcctagga
     3961 taaaaataaa caaatgactt acagcctcat cctccctaac tccatttgaa ctcaacttag
     4021 ctcacactca gtgataaaac aacatggtat gtagaagcct aggatcacag ggtgataatg
     4081 tcaattggca gccagttgtg tttttttgaa acatcattat tggcagtttc tccttatcac
     4141 cactgcttta atgtagtttt tttgtaaatc catatacttt aatgcataca ctctagctta
     4201 agaaaacatt gccattttgg ttagggatat gacttaatgt gctattattt ctggttctaa
     4261 tgaagaataa taccctatga ctttaagtgt aagattcatc ctttaagtag ggatgtttag
     4321 gataagttag atgtgtgcca ctatgattta ttgggtttct taaaaatctt gaagaaaata
     4381 ataaaattta tctcacaata agttaacttg cgcaaacttt ttacatatgg tgaggtgcgt
     4441 aaggaagccc tggccaactt aaagattttt ctggaggttc agcaaagtta tgttaaatta
     4501 ggggcctttg gtctcatcct tctctgactc ttctacccag tcttttccta aagttcggtg
     4561 ctactccagt tgggtgcatc agggagctcc gtcagcactc gcatgtgtcg ctcaggtggc
     4621 cactcatgcc tgcattccat ttaatagagt caattggaat ttttagagca taatctttat
     4681 ggatcctcaa agctgacttt gccaaaggga ttgagaccct tactaccatc aaatctctgt
     4741 ctctgcttgg ttaaaaattg gctcactatt gctttgtagt aacccctgcc caggtatttt
     4801 ttcacttgtg aaaataattt gagaaagacc tttgttccta gcctgttggg aaaagtttat
     4861 aattttatga aaattaagta cagaggctgc gatcttagaa ataatgaagg tgccatttgg
     4921 ctgctcctta atagtgcaga cagaaaactg cagtgaacac atgccaaaac atgattgaag
     4981 cctttggctg aaactttata catagaaata atgatttgct cataacaggt atcattaact
     5041 gccacttttt atgttttccc tagaatttgt agccttgctg cttgcttttc ttctgggtgg
     5101 caaagttact actggaaaaa cactataagt acaaagtttt tggggtttta tctttgcttt
     5161 agaagtggat gtgtacttca cctcttggct gtggaggaac ttagttgcca ggaaattttt
     5221 tttttttttt tcagacggag tttcgctctt gttgcccagg ctgggagggc aatggcaccg
     5281 tcttggctca ctgcaacctc cgcctcccgg gttccagcga ttctcctgcc tcagccttcc
     5341 gagtagctgg gattacaggc tcctgccacc acgcctggct aggaaatttt ttgttgttaa
     5401 tatgacattt ggattaatct ccagcttcaa cagtacttct tttgtccata aatctcagga
     5461 atgttttagg cagaaaactg gttttaccct gttgataatc agaaggagtg tgctttagga
     5521 tttattgcat aatactattc tttaattgca atcctaggta tctatagcat gagtggcctt
     5581 agtgagtttg ttgaagtgca catgtttttc aagagtaaaa tttaagatta aaaatatatc
     5641 ctatatatag atatctagaa aacttggttt gtggtgcaca gttaagtgtt ggatcactaa
     5701 ataaccattg caggtaccgt ttgtgtaaca ttactcattt ctgtatattc cttttatggg
     5761 aagatatttt gccatggtaa ctaaaacttt tcagttctac ttttatgatg tgaatgaatg
     5821 ctacgtttta ttaaatatta ccaggtcagt actattttta tactttatta agcaacaggg
     5881 gattttagtt taataggctc aaaataaaaa gttcttaatg gaacagttaa aaacaaaaca
     5941 ctaacaatct ttacgtgaaa atccccacta atagtgccac aataatttct atagaaatat
     6001 ctaaggtcat taaatagatt tttgaagacg gttcttcatt gtgtcaggat gacctttcat
     6061 atcattctca ccaacttgta gtgcccaccg ttatttgtaa ctattaaacc atactaagta
     6121 tgtttgtaac cagcattgtg atatattctg tacttgtatt gctaaaaatg aattattgac
     6181 ctaataaata tagtgttcct gca
//
