LOCUS       XM_011524450            6031 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens adaptor related protein complex 2 subunit
            beta 1 (AP2B1), transcript variant X3, mRNA.
ACCESSION   XM_011524450
VERSION     XM_011524450.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011524450.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6031
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..6031
                     /gene="AP2B1"
                     /gene_synonym="ADTB2; AP105B; AP2-BETA; CLAPB1"
                     /note="adaptor related protein complex 2 subunit beta 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 204 ESTs, 2213 long SRA reads, 2
                     Proteins, and 98% coverage of the annotated genomic
                     feature by RNAseq alignments, including 42 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:163"
                     /db_xref="HGNC:HGNC:563"
                     /db_xref="MIM:601025"
     CDS             366..3317
                     /gene="AP2B1"
                     /gene_synonym="ADTB2; AP105B; AP2-BETA; CLAPB1"
                     /codon_start=1
                     /product="AP-2 complex subunit beta isoform X1"
                     /protein_id="XP_011522752.1"
                     /db_xref="GeneID:163"
                     /db_xref="HGNC:HGNC:563"
                     /db_xref="MIM:601025"
                     /translation="MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVG
                     KDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLI
                     RALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQG
                     FLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWG
                     QIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDY
                     YNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYV
                     KLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCV
                     STLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIW
                     IVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLS
                     LATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICH
                     IGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQ
                     GDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSF
                     IPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEIS
                     GTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDV
                     SLPLNTLGPVMKMEPLNNLQVKSKENNWMDTSGRENANIMEKGIQAPFKVRKVAVKNN
                     IDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKL
                     QNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTLSLKCRAPEVSQY
                     IYQVYDSILKN"
ORIGIN      
        1 agacctagaa aagaatcgtg acgggcagga aaccattaca ccaccacctg ggctgtgctc
       61 tccggctccc gccgccaccc ccgccctcgc cttcgcctcc gcctccggtg agttcagggc
      121 ggttgccttt agggtgtgtc cctaattgac ggggtcgggg acggagagaa gggtaacacc
      181 aggctgggtc ggagaccggc ggaggcgagg aaatcctaag agcgtgaccg ttgatgatgc
      241 agggaaccgt cgggtgtgac cattgagagg gaaaaggttg gagaaagggt ctctaccatg
      301 atgcctgtgg tgcggtgagg gaatcctcgg gtgtggcagc aggtgcacat taaagatcca
      361 aagtcatgac tgactccaag tatttcacaa ccaataaaaa aggagaaata tttgaactaa
      421 aagctgaact caacaatgaa aagaaagaaa agagaaagga ggctgtgaag aaagtgattg
      481 ctgctatgac cgtggggaag gatgttagtt ctctctttcc agacgtagtg aactgtatgc
      541 agactgacaa tctggaacta aagaagcttg tgtatctcta cttgatgaac tacgccaaga
      601 gtcagccaga catggccatc atggctgtaa acagctttgt gaaggactgt gaagatccta
      661 atcctttgat tcgagccttg gcagtcagaa ccatggggtg catccgggta gacaaaatta
      721 cagaatatct ctgtgagccg ctccgcaagt gcttgaagga tgaggatccc tatgttcgga
      781 aaacagcagc agtctgcgtg gcaaaactcc atgatatcaa tgcccaaatg gtggaagatc
      841 agggatttct ggattctcta cgggatctca tagcagattc aaatccaatg gtggtggcta
      901 atgccgtagc ggcattatct gaaatcagtg agtctcaccc aaacagcaac ttacttgatc
      961 tgaacccaca gaacattaat aagctgctga cagccctgaa tgaatgcact gaatggggcc
     1021 agattttcat cctggactgc ctgtctaatt acaaccctaa agatgatcgg gaggctcaga
     1081 gcatctgtga gcgggtaact ccccggctat cccatgccaa ctcagcagtg gtgctttcag
     1141 cggtaaaagt cctaatgaag tttctagaat tgttacctaa ggattctgac tactacaata
     1201 tgctgctgaa gaagttagcc cctccacttg tcactttgct gtctggggag ccagaagtgc
     1261 agtatgtcgc cctgaggaac atcaacttaa ttgtccagaa aaggcctgaa atcttgaagc
     1321 aggaaatcaa agtcttcttt gtgaagtaca atgatcccat ctatgttaaa ctagagaagt
     1381 tggacatcat gattcgtttg gcatctcaag ccaacattgc tcaggttctg gcagaactga
     1441 aagaatatgc tacagaggtg gatgttgact ttgttcgaaa agctgtgcgg gccattggac
     1501 ggtgtgccat caaggtggag caatctgcag agcgctgtgt aagcacattg cttgatctaa
     1561 tccagaccaa agtgaattat gtggtccaag aagcaattgt tgtcatcagg gacatcttcc
     1621 gcaaataccc caacaagtat gaaagtatca tcgccactct gtgtgagaac ttagactcgc
     1681 tggatgagcc agatgctcga gcagctatga tttggattgt gggagaatat gctgaaagaa
     1741 ttgacaatgc agatgagtta ctagaaagct tcctggaggg ttttcacgat gaaagcaccc
     1801 aggtgcagct cactctgctt actgccatag tgaagctgtt tctcaagaaa ccatcagaaa
     1861 cacaggagct agtccagcag gtcttgagtt tggcaacaca ggattctgat aatcctgacc
     1921 ttcgagaccg gggctatatt tattggcgcc ttctctcaac tgaccctgtt acagctaaag
     1981 aagtagtctt gtctgagaag ccactgatct ctgaggagac ggaccttatt gagccaactc
     2041 tgctggatga gctaatctgc cacattggtt ctttggcctc tgtgtatcat aagcctccca
     2101 atgcttttgt ggaaggaagt catggaattc atcgtaaaca cttgccaatt catcatggga
     2161 gcactgatgc aggtgacagc cctgttggca ctaccactgc aacgaacctg gaacagcctc
     2221 aggttatccc ctctcaaggt gatcttctag gggatctttt aaaccttgac ctcggtcccc
     2281 cagtcaatgt gccacaggtg tcctccatgc agatgggagc agtggatctc ctaggaggag
     2341 gactagatag tctgcttggc agtgaccttg gcgggggcat tggaggaagt ccggcagtgg
     2401 gacaatcctt catcccatca tcggtgcctg caacctttgc tccttcacct acacctgctg
     2461 tggtcagcag tggactgaat gacctgtttg aactctccac agggataggc atggcacctg
     2521 gtggatatgt ggctcctaag gctgtctggc tacctgcagt aaaggctaaa ggcttggaga
     2581 tttccggaac atttactcac cgccaagggc acatctatat ggaaatgaac ttcaccaata
     2641 aagctctgca gcacatgaca gattttgcaa tccagtttaa caaaaatagc tttggtgtca
     2701 tccccagcac tcctctggcc atccatacac cactgatgcc aaaccagagc attgatgtct
     2761 ccctgcctct caataccttg ggcccagtca tgaagatgga acctctgaat aacctccagg
     2821 ttaaaagcaa ggagaataat tggatggaca cttctgggag agagaacgca aatattatgg
     2881 agaagggaat acaggcacca tttaaagtaa ggaaggtggc tgtgaaaaac aatatcgatg
     2941 tcttctactt cagctgcctc atcccactca atgtgctttt tgtagaagat ggcaaaatgg
     3001 agcgccaggt cttccttgca acatggaagg atattcccaa tgaaaatgaa cttcagtttc
     3061 agattaagga atgtcattta aatgctgaca ctgtttccag caagttgcaa aacaacaatg
     3121 tttatactat tgccaagagg aatgtggaag ggcaggacat gctgtaccaa tccctgaagc
     3181 tcactaatgg catttggatt ttggccgaac tacgtatcca gccaggaaac cccaattaca
     3241 cgctgtcact gaagtgtaga gctcctgaag tctctcaata catctatcag gtctacgaca
     3301 gcattttgaa aaactaacaa gactggtcca gtacccttca accatgctgt gatcggtgca
     3361 agtcaagaac tcttaactgg aagaaattgt attgctgcgt agaatctgaa cacactgagg
     3421 ccacctagca aggtagtaac tagtctaacc tgtgctaaca ttagggcaca acctgttgga
     3481 tagttttagc ttcctgtgaa catttgtaac cactgcttca gtcacctccc acctcttgcc
     3541 acctgctgct gctatctgtc cttacttgtg ggcttctcca tgctgtgcca atggctggct
     3601 ttttctacac cctcttttga gtgtagtttg gtattttgta attgagagct catttcaaaa
     3661 gcagaaaaag acaacaaata ttaaagcaag gaaaagtgta actgaaacac tgcactttac
     3721 tgttttatac ttttgtacat atgagaaatc aagggattag tgcaaccagt agaaagcatt
     3781 gaaatgactg tcattaacca cacagtcctg gaggcagaga tgcagttacc taccctagct
     3841 tttgatgggt tctcttacct gtagtagcct tatccctggt catttggatt ttcagtttgc
     3901 ttttttcttt ttttcccctc caaactcctt ttccttggcc aagccttcat gcttccccct
     3961 ttccatatta taatctcatt tgattgctct gcagttggga acggtgatct tcttgaatga
     4021 tgtttcagtg tgcaaaaact atagagcctg tcagcaccaa agctgacaga agttatacct
     4081 tactcctttc ctttcccctg aacaaacctg ctaatcccac taattcagga atttgagtag
     4141 agatggggaa caagaaccca gatgctgtcc cctcaccccc tctcctgtat ttctcaggtc
     4201 cagttcaaat ctaaaattct acttttagag ttgaaacaga gtaataactt atctaaccct
     4261 cttttcctac aaaggagaaa gataaaaggc acaaaggtta ccgccaaggc ccgtcagctg
     4321 tgtagtggca aagccgagac cgagtctcct aagtccccgt cagtgtggtt ttcaccacag
     4381 gactgtctct tgtcgttttc ccctaatgcc ttctcctgcc ttttctgtgc ctagtttttg
     4441 gctcttcaca tattccatat tgattttgac gctctgtata ttggcatcag gtggcagctg
     4501 aatatctttt gaattactcg aaggtaaagc cagatgccag aatgaaggtg tagccagtgt
     4561 ttcccatatg cccctggagc cccacttatt gaggccagca gaataggtgc agagatgaag
     4621 tgagcttaga gatgttgcaa atgctcttta tcccttcagc tctctgatct gctctttctt
     4681 catgatactt agtctgcagg gcatattaag atcatcccag aggttcaggc agttcctgtc
     4741 atctctgaaa agactggggg atatgaaatc ttccccctac cccacttaat gcgttggata
     4801 tgatttttca aagaatgctt catgcccaaa ataccagcct gtttagcagt gttacactgt
     4861 ttgatctgcg ggcacttgtt gcattgcctg gcacccaata ttcagggtcc atgactaaga
     4921 ctggtcttct cagatgccct gcttaaatca ggggcacttc aggctccaca ggcgtcatgt
     4981 tggactgaga cctaactcac tggactcaga ggaggaatcg tggaaaacaa gagcaaaact
     5041 accccacacc cctatttcat gtctgaaata accctgtttc ataccagttg caaagcttgt
     5101 ggggagcggt cccacaaagc actttcttaa accttgagaa tctccaagag aaaaatattt
     5161 ggggaaggag ggaggaaata tgtcccttgc acaccacccc tgaagcacat ggcagtagga
     5221 aacagcatag gattgtatgt gggaggtgga taggtcggtg atgtgtggag cggaaaagca
     5281 ggttggtaaa gttcccttct tgggacttat tcctggagtc agtggataca agtagtgcag
     5341 aaggttcaca ctgcaaatag tgttctcatc tcaaagcaaa ctatcattcc agaaggaaaa
     5401 gtgtgtcagg gcaagcagac aacacaattt cctatcagaa tatgtccctc aacccccgaa
     5461 acaaggcttc tctcagcctc cccaccagtg atggataaca gctcctattc tcagctgacc
     5521 tgactgagcc aacccatgaa ctcttcactc cttggggaag ccacctccca tcacacccct
     5581 gagcagagtt agggaggaat tctacttccc ataaaaggac ctctcctgag aggcaaaacc
     5641 tgttgcctcc accacggctt ccctcttggc tcattccaag cttggccaaa ttggggaagt
     5701 gggatggagg ttgccctgca tcccccctcc tctgcctgag tgtgtctttg taatgtcagc
     5761 tggcatcata caaagagcag gagaagcaaa cacccagaac tcttttgctg gtcagagatt
     5821 ccctgagtgt ctgtcctcac ccaagcctgc tctgtgtctg tgttgtgaag cttgagactc
     5881 tggaaagaaa tggggagggg gggcagggga aatgttgccc taagaatgct tctcattcct
     5941 ctgttcttat tgggtcctgt ttttcgggag ggtgggggtt gggggaagct tgaccttgtg
     6001 tcttcgtcaa taaactcaca tttacacaaa a
//
