LOCUS       XM_017015232            5139 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens aminopeptidase O (putative) (AOPEP),
            transcript variant X15, mRNA.
ACCESSION   XM_017015232
VERSION     XM_017015232.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000009.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017015232.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5139
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
     gene            1..5139
                     /gene="AOPEP"
                     /gene_synonym="AP-O; APO; C90RF3; C9orf3; DYT31; ONPEP"
                     /note="aminopeptidase O (putative); Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 14 ESTs, 288 long SRA reads, 2 Proteins, and 95%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 21 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:84909"
                     /db_xref="HGNC:HGNC:1361"
                     /db_xref="MIM:619600"
     CDS             189..2309
                     /gene="AOPEP"
                     /gene_synonym="AP-O; APO; C90RF3; C9orf3; DYT31; ONPEP"
                     /codon_start=1
                     /product="aminopeptidase O isoform X8"
                     /protein_id="XP_016870721.1"
                     /db_xref="GeneID:84909"
                     /db_xref="HGNC:HGNC:1361"
                     /db_xref="MIM:619600"
                     /translation="MDIQLDPARDDLPLMANTSHILVKHYVLDLDVDFESQVIEGTIV
                     LFLEDGNRFKKQNSSIEEACQSESNKACKFGMPEPCHIPVTNARTFSSEMEYNDFAIC
                     SKGEKDTSDKDGNHDNQEHASGISSSKYCCDTGNHGSEDFLLVLDCCDLSVLKVEEVD
                     VAAVPGLEKFTRSPELTVVSEEFRNQIVRELVTLPANRWREQLDYYARCSQAPGCGEL
                     LFDTDTWSLQIRKTGAQTATDFPHAIRIWYKTKPEGRSVTWTSDQSGRPCVYTVGSPI
                     NNRALFPCQEPPVAMSTWQATVRAAASFVVLMSGENSAKPTQLWEECSSWYYYVTMPM
                     PASTFTIAVGCWTEMKMETWSSNDLATERPFSPSEANFRHVGVCSHMEYPCRFQNASA
                     TTQEIIPHRVFAPVCLTGACQETLLRLIPPCLSAAHSVLGAHPFSRLDVLIVPANFPS
                     LGMASPHIMFLSQSILTGGNHLCGTRLCHEIAHAWFGLAIGARDWTEEWLSEGFATHL
                     EDVFWATAQQLAPYEAREQQELRACLRWRRLQDEMQCSPEEMQVLRPSKDKTGHTSDS
                     GASVIKHGLNPEKIFMQVHYLKGYFLLRFLAKRLGDETYFSFLRKFVHTFHGQLILSQ
                     DFLQMLLENIPEEKRLELSVENIYQDWLESSGIPKPLQRERRAGAECGLARQVRAEVT
                     KWIGVNRRPRKRKRREKEEVFEKF"
     polyA_site      5139
                     /gene="AOPEP"
                     /gene_synonym="AP-O; APO; C90RF3; C9orf3; DYT31; ONPEP"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gtagtaaccc cgagtctgcg gaagtggtga cccgtgggac gcggctgaga caggagactg
       61 aaaggaacca taatttgtga catcagttgt tttctttgat aagcagctat ttatgattct
      121 ggaagattaa ggcagatagg aaaccccatc tgagatttta ataaatccct caaacaataa
      181 accacatcat ggacatacag ctggaccctg ccagagatga cctgcctctc atggccaaca
      241 ccagccacat acttgtgaag cactatgtac tggatttgga tgtggatttt gaaagtcaag
      301 tcattgaggg gaccatagtg cttttcctcg aggatggaaa cagattcaag aaacagaata
      361 gctctattga ggaagcctgc caatcagaat caaacaaagc ctgcaaattt gggatgcctg
      421 aaccctgcca tattcccgtg acaaatgcaa ggaccttctc atctgaaatg gaatataatg
      481 attttgcaat ctgtagtaaa ggtgaaaaag atacttctga taaagatggt aaccatgaca
      541 accaggaaca tgcttctggg atttctagct caaagtactg ctgtgacaca gggaatcatg
      601 ggagtgagga ttttttgcta gtgttggact gctgtgattt atctgtgtta aaagtcgagg
      661 aggtggatgt tgctgctgtg ccaggtctgg aaaaatttac aaggtctcct gagctcacgg
      721 ttgtttctga ggagttcagg aatcagattg tacgtgaact tgtgactttg cctgcaaatc
      781 gttggaggga gcagttagac tattacgctc gctgcagcca ggctcctggc tgtggggaac
      841 tcctctttga cactgacact tggagcttgc agataaggaa gacaggggct cagacagcta
      901 ctgactttcc tcatgctatc aggatatggt acaaaactaa acctgaaggg cgatcggtta
      961 catggacctc agaccagagt ggcaggccat gtgtttatac tgtgggatct cccataaaca
     1021 acagggccct ttttccatgc caggagccac ccgttgccat gtcaacatgg caggctacag
     1081 ttcgagcagc tgcatctttt gttgttttaa tgagtgggga aaattctgcc aaaccaacgc
     1141 agctttggga agagtgctca agctggtatt actatgtaac tatgccaatg ccagcctcca
     1201 ccttcacaat tgcagtggga tgctggacag aaatgaagat ggagacatgg tcatcaaatg
     1261 atttggcaac agagagaccc ttctcacctt ctgaggccaa cttcaggcat gttggtgttt
     1321 gcagtcacat ggaatacccc tgccgcttcc agaatgcttc tgccaccacc caggagatca
     1381 ttcctcatcg ggtctttgcc cctgtgtgcc tcacgggtgc ctgccaagag acccttctgc
     1441 ggctgatccc tccttgcctc tcagcagcac attctgttct gggagcacac ccgttctctc
     1501 ggctggatgt tctcatcgtc cctgccaact ttccaagtct ggggatggcc agcccacaca
     1561 tcatgttcct ctctcagagc atcttgacag gagggaacca tctctgtggg acccgcctct
     1621 gccatgaaat tgcccatgcc tggtttggcc tagccatcgg ggcccgagac tggacggagg
     1681 agtggctgag tgaaggcttc gccactcact tggaggatgt gttttgggcc acagcacagc
     1741 agctggcccc ctatgaggcc cgggagcagc aggagctgag ggcttgtctg cgctggcgtc
     1801 gcctccagga cgagatgcaa tgctcccccg aggagatgca ggtgttaaga cccagtaaag
     1861 acaaaactgg ccacacaagt gactcgggag catctgttat caagcatgga cttaatccgg
     1921 agaagatctt catgcaggtg cattatttaa agggctactt ccttcttcgg tttcttgcca
     1981 aaagacttgg agatgaaacc tatttttcat ttttaagaaa atttgtgcac acatttcatg
     2041 gacagctgat tctttcccag gatttccttc aaatgctact ggagaacatt ccagaagaaa
     2101 aaaggcttga gctgtctgtt gaaaacatct accaagactg gcttgagagt tccggaatac
     2161 caaagccgct gcagagggag cgtcgcgccg gggcggagtg cgggcttgcg cggcaagtgc
     2221 gcgccgaggt cacgaaatgg attggagtga accggagacc ccgaaaacgg aagcgcaggg
     2281 agaaggaaga ggtgtttgaa aagttttgat ttgaagttcc tttaaaggct gttggagctt
     2341 ttgcaaatac ccagctaatg aaaggcactt aagattgggc ccatgtgcat catcacattg
     2401 aagttttctg tctaaaggaa ggttccagct acctgttacc cttttgctaa acacagttgc
     2461 agtgttgcag tgtatttcat gacaaaagtg tactctagtt ttctgtgaaa tgattatttt
     2521 ctctgaaatg attcttggtc atgttgagct tctaaatgtt aaagagaaca tagtgctttt
     2581 gacctgtgga aatctcatct tggtaccatg gtgctgcaca gaccatcagg aagaactgaa
     2641 aagttcaggc aacttgagaa aataaagtca ccaccagcaa gaagctgtct aaaataaccg
     2701 gaagattata acccaagcac gtggaggagt gtgctagtga gtagaatgtt atgaaagcta
     2761 ctagaggtcc tccatagatg catgtgctag tcctaaggag aaggaagagg agaaggattg
     2821 ccacggagga acacctgaag tttcagttga gcactttgtt tggaaagttg tccaaggctg
     2881 gagttgtgag agctgggaaa gacctcacaa gcttctctaa ttcaagtcct tgtttcacat
     2941 atgagaatgc agaggccctg agaagttgat tcccaggcct gcatgctggc ctggaactag
     3001 agcctgggtc tcctcttgct ttttccagct gtctgcccag gtagctcccc aaggcaggca
     3061 tggaggcaga gctgctttgg gttccaggta aggagagatg tgtccaggtg gcctttgttg
     3121 tattgtgggg cacagacact gagggagaca gggaaaggtc tgggagacac aagatggtac
     3181 cccagaaggc catcctttgt agactagaca cacatccaaa gggagggctg tttcctggct
     3241 tattgaggac ttttccattt gggctagaag taaactgagt cagattttga gagatcagta
     3301 attccaaaga gcagataagg attctatagt aacacagctg ggttcactgc acgggttgat
     3361 gtcaaattgt gcttttcatg ttacattagt ggattttaca aggcacagat tatttgacat
     3421 ttttgtgatg cttgttatag accaactgtg acatgacagt attatttaaa aaaaaaaaaa
     3481 gaaatatagg gccaggcatg atggctcacg cctatagttt cagcactttg ggaggctgag
     3541 gcaggtggat cgcttgagct caggagttca agaccaacct cggcaacatg gtgaaacccc
     3601 gtctctacta aaaatgcaaa aattagccag gtgtggtggt gcatggctgt ggtcccagct
     3661 actcaggagg ctgaggtggg aggattgcct gagcctggga ggtggaggtt gcagttaagc
     3721 cgagattgcg ccactgtact ccagcctggg caacagagtg agaccttgtc tcaaaaaaaa
     3781 aaaaaaaaaa gacataagca tgaccagata aattgacatt ttgttttgaa atgcagtaat
     3841 ggcactctca caaatgacct tttcaccagt ctgtgctggt atttgtaaat atatatgtta
     3901 gtattgtttt ctaaaatgca aagctgattt tcatgtttat atatattcat accttgatat
     3961 attgcaattt tagagtttct gcagtctgtc taacttggct gtttgttcat aggccagatc
     4021 aaactaccct cattccccaa aacttggatt gtgaagggat tagtgcccca gaactctctg
     4081 tgttactggc agggcaaaat gggtaggaat agtctggctt agggaaaaag acatattttc
     4141 tctctaacac aactggcaga tactgaagtg ggcaggtggc aagaaaaggc aagtactgag
     4201 ctgattcaga cttgcagaaa gcttcctctc ctccttctta gcaaaatgaa aggctctggg
     4261 aaaaggcacc tgcctttccc tgccttgagg atcctggcat ccttgagtct ttattgaaga
     4321 ttaatttaat gacttggtca acaatagcat tacctaatca cagagcatca gattatcata
     4381 agacaaattt aaatgatgcc gaagtatctt ccagcagagg attagtgatg taccagcatg
     4441 catgtgtagc ttgtgtgggt gtgtgtgcat acaagcatgc acatgtgcgc acacacacag
     4501 agagtctaat tggcctttgt cctctgagca gggggcaggt ttgggctggg gcctgctgtg
     4561 tgaccacagt ctcccatctt agattgaagc tacatcgctg tgtgcatcta actcttgatt
     4621 cacggtctga ccgacgcctt ggtttctgga gaactgccct cgtttatgga agagtcactg
     4681 tcatcaggag ccatcccagg gagaggctca gtgggaagtg taaaggtgga gcaagtaaac
     4741 cggctccaga agagaaggcg aagaaggact atttctgttt agatttgctt aaccgcattt
     4801 tcactttctt gggaacccct gatggagttc aaggtcatag aagagaagaa atcagacact
     4861 gctacaggac tcttgctctt ggttcagatt attcaatggg aggggagaag agagtagtcg
     4921 caagtgattg ttgtagattt tgtctcagct ttttgttttt ctttgtatca aacctgtttt
     4981 gagatcatac actgttacag agaaagagag gaggcatatt ataaacgtgt ggacttcagt
     5041 gttattcctt ctcttcaaaa tgatgttcca ggtgtctaga gggtgaggta tgtcatttac
     5101 atgaaggtta agaataaaac agaaagtgcc tctatggta
//
