LOCUS       NM_001162435            1330 bp    mRNA    linear   PRI 17-FEB-2024
DEFINITION  Homo sapiens ankyrin repeat domain 66 (ANKRD66), mRNA.
ACCESSION   NM_001162435 XM_002342601 XM_002346780
VERSION     NM_001162435.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1330)
  AUTHORS   Ota,T., Suzuki,Y., Nishikawa,T., Otsuki,T., Sugiyama,T., Irie,R.,
            Wakamatsu,A., Hayashi,K., Sato,H., Nagai,K., Kimura,K., Makita,H.,
            Sekine,M., Obayashi,M., Nishi,T., Shibahara,T., Tanaka,T.,
            Ishii,S., Yamamoto,J., Saito,K., Kawai,Y., Isono,Y., Nakamura,Y.,
            Nagahari,K., Murakami,K., Yasuda,T., Iwayanagi,T., Wagatsuma,M.,
            Shiratori,A., Sudo,H., Hosoiri,T., Kaku,Y., Kodaira,H., Kondo,H.,
            Sugawara,M., Takahashi,M., Kanda,K., Yokoi,T., Furuya,T.,
            Kikkawa,E., Omura,Y., Abe,K., Kamihara,K., Katsuta,N., Sato,K.,
            Tanikawa,M., Yamazaki,M., Ninomiya,K., Ishibashi,T., Yamashita,H.,
            Murakawa,K., Fujimori,K., Tanai,H., Kimata,M., Watanabe,M.,
            Hiraoka,S., Chiba,Y., Ishida,S., Ono,Y., Takiguchi,S., Watanabe,S.,
            Yosida,M., Hotuta,T., Kusano,J., Kanehori,K., Takahashi-Fujii,A.,
            Hara,H., Tanase,T.O., Nomura,Y., Togiya,S., Komai,F., Hara,R.,
            Takeuchi,K., Arita,M., Imose,N., Musashino,K., Yuuki,H., Oshima,A.,
            Sasaki,N., Aotsuka,S., Yoshikawa,Y., Matsunawa,H., Ichihara,T.,
            Shiohata,N., Sano,S., Moriya,S., Momiyama,H., Satoh,N., Takami,S.,
            Terashima,Y., Suzuki,O., Nakagawa,S., Senoh,A., Mizoguchi,H.,
            Goto,Y., Shimizu,F., Wakebe,H., Hishigaki,H., Watanabe,T.,
            Sugiyama,A., Takemoto,M., Kawakami,B., Yamazaki,M., Watanabe,K.,
            Kumagai,A., Itakura,S., Fukuzumi,Y., Fujimori,Y., Komiyama,M.,
            Tashiro,H., Tanigami,A., Fujiwara,T., Ono,T., Yamada,K., Fujii,Y.,
            Ozaki,K., Hirao,M., Ohmori,Y., Kawabata,A., Hikiji,T., Kobatake,N.,
            Inagaki,H., Ikema,Y., Okamoto,S., Okitani,R., Kawakami,T.,
            Noguchi,S., Itoh,T., Shigeta,K., Senba,T., Matsumura,K.,
            Nakajima,Y., Mizuno,T., Morinaga,M., Sasaki,M., Togashi,T.,
            Oyama,M., Hata,H., Watanabe,M., Komatsu,T., Mizushima-Sugano,J.,
            Satoh,T., Shirai,Y., Takahashi,Y., Nakagawa,K., Okumura,K.,
            Nagase,T., Nomura,N., Kikuchi,H., Masuho,Y., Yamashita,R.,
            Nakai,K., Yada,T., Nakamura,Y., Ohara,O., Isogai,T. and Sugano,S.
  TITLE     Complete sequencing and characterization of 21,243 full-length
            human cDNAs
  JOURNAL   Nat Genet 36 (1), 40-45 (2004)
   PUBMED   14702039
REFERENCE   2  (bases 1 to 1330)
  AUTHORS   Bonaldo,M.F., Lennon,G. and Soares,M.B.
  TITLE     Normalization and subtraction: two approaches to facilitate gene
            discovery
  JOURNAL   Genome Res 6 (9), 791-806 (1996)
   PUBMED   8889548
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL451143.15 and AL161618.17.
            
            On Aug 14, 2020 this sequence version replaced NM_001162435.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803616.31604.1, AK304342.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2144333, SAMEA2147920
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000565422.3/
                                                ENSP00000454770.2
            RefSeq Select criteria           :: based on manual assertion,
                                                conservation, expression,
                                                longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-58                AL451143.15        14489-14546
            59-142              AL451143.15        17452-17535
            143-317             AL451143.15        19493-19667
            318-546             AL451143.15        21278-21506
            547-1330            AL161618.17        6055-6838
FEATURES             Location/Qualifiers
     source          1..1330
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p12.3"
     gene            1..1330
                     /gene="ANKRD66"
                     /note="ankyrin repeat domain 66"
                     /db_xref="GeneID:100287718"
                     /db_xref="HGNC:HGNC:44669"
     exon            1..58
                     /gene="ANKRD66"
                     /inference="alignment:Splign:2.1.0"
     exon            59..142
                     /gene="ANKRD66"
                     /inference="alignment:Splign:2.1.0"
     exon            143..317
                     /gene="ANKRD66"
                     /inference="alignment:Splign:2.1.0"
     CDS             155..745
                     /gene="ANKRD66"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein 66"
                     /protein_id="NP_001155907.3"
                     /db_xref="CCDS:CCDS59024.2"
                     /db_xref="GeneID:100287718"
                     /db_xref="HGNC:HGNC:44669"
                     /translation="MELAKMSDMTKLHQAVAAGDYSLVKKILKKGLCDPNYKDVDWND
                     RTPLHWAAIKGQMEVIRLLIEYGARPCLVTSVGWTPAHFAAEAGHLNILKTLHALHAA
                     IDAPDFFGDTPKRIAQIYGQKACVAFLEKAEPECQDHRCAAQQKGLPLDERDEDWDAK
                     KRELELSLPSLNQNMNKKNKKSRGPTRPSNTKGRRV"
     exon            318..546
                     /gene="ANKRD66"
                     /inference="alignment:Splign:2.1.0"
     exon            547..1330
                     /gene="ANKRD66"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actccggatg gttaggactg cctgtcagca cagagctcct caaatttcac acaagacagg
       61 ctgttctcac atttcaatgc actcacctgg agggcttacc acaacaaaga tggccggacc
      121 cctgcccaga gtttcagatt ctttgttttc tgccatggaa ttggccaaaa tgtcagacat
      181 gacaaagctt caccaagctg tggctgcagg agactacagc ttagtgaaga agattttgaa
      241 gaaaggtctc tgtgacccaa actacaaaga tgtagactgg aatgaccgga ccccacttca
      301 ctgggctgca atcaaagggc aaatggaggt gatacggctc ctgatagaat atggagccag
      361 gccctgcctg gttactagtg tgggctggac cccagctcat tttgcagcag aagcaggcca
      421 tctgaatata ctcaaaactc tccatgcatt gcacgctgcc atcgacgccc ctgacttctt
      481 tggagacaca ccgaagagga ttgcacagat ctatggacag aaagcctgtg tggcatttct
      541 ggaaaaggca gagcccgagt gccaggacca ccgttgcgct gcccagcaga aggggctgcc
      601 tctggatgag cgtgatgaag actgggatgc caagaaaagg gagctggagc tgtctcttcc
      661 ttccctaaat caaaacatga ataaaaagaa taagaaaagt cgaggcccca ccaggcccag
      721 caataccaag gggaggagag tatgagaact caaccttatg ttttctggca aggaactttc
      781 cctggtgcca gaaatgaggc tgttaggcat ggtggccttt ccatgacttt actcatagac
      841 ccttacccac ctggcttctg cccatggacc tgtcattagg tgctgtccac atgggctgtt
      901 gtttcctggc tagcacctac tgtgtacaat aattaccggg aaaggacaaa acctgcttgc
      961 attttgtcat cagtggtttg cacagtcagc atcttttgac ccctgccccc caacaataat
     1021 agaatttcag gagacaagga aactctggca tgaattaact tcatccctga taacgatcga
     1081 gagataatgt aaaataatga acatgtgatt ataggtctac tttttcaact gtaaatttgg
     1141 gaaaattaaa ttcagatcag ataattccaa taaaaaattg catccaaatt gagatgcaaa
     1201 atacacatta gatttcaaac acttagtaca aaaatataaa atgtctcctt aataatactt
     1261 aatattgatt ccacattgaa atgataatat tttggatatt gcgttgaata agatatatta
     1321 ccaaaatgaa
//
