LOCUS       NM_001190479            4693 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens ankyrin repeat domain 63 (ANKRD63), mRNA.
ACCESSION   NM_001190479 XM_001725332
VERSION     NM_001190479.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4693)
  CONSRTM   Schizophrenia Working Group of the Psychiatric Genomics Consortium
  TITLE     Biological insights from 108 schizophrenia-associated genetic loci
  JOURNAL   Nature 511 (7510), 421-427 (2014)
   PUBMED   25056061
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC020658.6.
            
            On Sep 23, 2020 this sequence version replaced NM_001190479.2.
            
            Sequence Note:.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000434396.2/ ENSP00000399547.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4693              AC020658.6         116747-121439       c
FEATURES             Location/Qualifiers
     source          1..4693
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q15.1"
     gene            1..4693
                     /gene="ANKRD63"
                     /note="ankyrin repeat domain 63"
                     /db_xref="GeneID:100131244"
                     /db_xref="HGNC:HGNC:40027"
     exon            1..4693
                     /gene="ANKRD63"
                     /inference="alignment:Splign:2.1.0"
     CDS             479..1621
                     /gene="ANKRD63"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein 63"
                     /protein_id="NP_001177408.1"
                     /db_xref="CCDS:CCDS53929.1"
                     /db_xref="GeneID:100131244"
                     /db_xref="HGNC:HGNC:40027"
                     /translation="MLKPKDLCPRAGTRTFLEAMQAGKVHLARFVLDALDRSIIDCRA
                     EQGRTPLMVAVGLPDPALRARFVRLLLEQGAAVNLRDERGRTALSLACERGHLDAVQL
                     LVQFSGDPEAADSAGNSPVMWAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQL
                     AAARGHGTCVQALTGPWGRAAAAAAARGSNSDSPPGRPAPAASPEHRRPSPRRLPRPL
                     LARFARAAGGHGGEAGSAGKNSGRHRAQGSERPELGRSMSLALGAVTEEEAARLRAGA
                     LMALPNSPQSSGTGRWRSQEVLEGAPPTLAQAPIGLSPHPEGGPGSGRLGLRRRSTAP
                     DIPSLVGEAPGPESGPELEANALSVSVPGPNPWQAGTEAVVLRAQR"
     regulatory      4665..4670
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANKRD63"
                     /note="hexamer: AATAAA"
     polyA_site      4693
                     /gene="ANKRD63"
                     /note="major polyA site"
ORIGIN      
        1 gaggagcggc gcgccccgcc agggctggag gcaggcgtgc acggcgggcg ccaccgtcgc
       61 tgcgggggag cgggggctgc cctgggtgcg ggtgagtggc acggcggctc caaaccacga
      121 ggactgaggg gcgccggaca ccgggaaagc ggcgagagac tcgggagagg gtcgagtctc
      181 tgctcccgac gtctggtggc gggccaggag cggagcccgg agtagcgagc aatcaacacc
      241 tccaggcggg aggcccgggg aaggagcggc gacacgccag gcgtgcggcc caggagcggc
      301 ggggcagtcg gagcctccgg gacagcggag taggaacctc gggaccctcg gctgcagccg
      361 cccacgcgcg gagggagagg tatcagagcg cgggcggagg ccggagcccc gcggggcgcg
      421 agaacagggg cgcccccgtg cggaactgcc aggctgcccg ggcgcggcgg ccggggccat
      481 gctcaaaccc aaggacctgt gcccccgagc ggggacgcgc accttcctgg aggccatgca
      541 ggcgggcaaa gtgcacttgg cccgcttcgt gttggatgcg ctggaccgca gcatcatcga
      601 ctgccgcgcg gagcagggcc gtacgccgct catggtggcc gtggggctgc cggaccccgc
      661 gctgcgcgcg cgcttcgtgc ggctgctgct cgagcagggt gctgcagtga acctgcgaga
      721 cgagcgcggc cgcaccgcac tcagcctggc gtgcgagcga ggccacctgg acgccgtgca
      781 gctgctggtg cagttcagcg gtgaccccga ggcggccgac tctgcgggca acagcccggt
      841 gatgtgggcg gcggcctgcg gccacggggc ggtgctcgag ttcctggtgc ggtccttccg
      901 ccgcctaggc ctgcgcctcg accgcaccaa ccgtgcgggg ctcaccgcgc tgcaactggc
      961 cgccgcccgc ggccacggga cctgtgtgca ggccctcacc gggccctggg gccgcgccgc
     1021 cgccgccgct gcggcccggg gctccaactc cgatagtccc cctggccgcc cggcccccgc
     1081 ggccagcccc gagcatcgac gacccagccc ccgccgcctc ccgcggcctc tcctggcgcg
     1141 ctttgcgcga gcggcgggcg gccacggcgg cgaggctggc tcagcgggca agaattcggg
     1201 ccggcaccgg gcgcagggca gcgaacggcc cgagctgggt cggagcatga gcctggctct
     1261 aggtgcggta accgaggagg aggctgcccg cctgcgggct ggggccctga tggccctacc
     1321 aaactcgccc cagtcttcgg ggactgggcg gtggcgctca caggaggtgc tggagggagc
     1381 gcccccaacc ttagcgcaag cccccattgg cctcagtccc cacccggagg gcggccccgg
     1441 ctctggccgc ctgggtttgc gccgacgctc cacagcccca gatatcccca gcctggtcgg
     1501 ggaggcgcca gggcccgaga gtggcccgga gttagaggcc aacgctctgt ctgtctcggt
     1561 gcctgggccg aacccttggc aggcgggcac cgaggctgtg gtgctgcgtg ctcagcggta
     1621 aacggcgcca aggcccgagg cctgcttccc ctaccctccc gtttctactc cactggtatt
     1681 tctctcttct aggtccctca ccttttcggc agccgccccc cgcagtccat tttggaacct
     1741 gcctccctgc caaggcgaga cctccaccag ccctccacca gaaataaggg acctccatct
     1801 tcttttttgt gctcctcggt attccctgcc taggtctaga ggtgtcgatt gactggttcc
     1861 gtaggctaca gccaggaagg tggattcccc ctccccagcc ctcaggctca atcctgggtc
     1921 ggcctagcca tctgtcgctc ctgtccggcc cccctcccct cgctgggttt cccaacaact
     1981 gggcagccag gtaaatagaa gggtccacct tggagaataa ggacccagcc tccccacttt
     2041 ctgcctactg atgctgacaa taatcccaca aactaccaaa gtctcctttc cctccaagtg
     2101 tgggagaagg aaaggacgga gggggcccta gagcctttca ggactggagg gttgaggagg
     2161 aaggggtctg gctgttatgt ttttccaggg tagaaactcc tgtctcaaga caatgaaagc
     2221 atattttggg agtgggagag tccctagtgt tgaacaccag ttgtcccttg aatcagctcc
     2281 tgggtaactc cagctccctc tctctctgcc ccaggattca gcttcattga taatgtggag
     2341 tcactgctcc acacaacccc tacccaggcc aactccgggc tccagagcca gcccgctctt
     2401 cagctcagat gcatttgaat tccatcatcg aggttcaaca cctcacccct ggaggcccaa
     2461 gccctatttc cgctgggtca cagaggcctg aaatggaaag gactgagcgc ttccccgcct
     2521 ccacgcctcc cagctccccc gtcccgcacg tgggtgctcc cgcggggtgg aacggttgcg
     2581 aaggctgtgc ttaattgtat ttcttccaat cctcaaagaa ctcgtgtttt aagcctttgt
     2641 atatgaagca gaaagcagcg ggtctgattc cgaggcttaa gagcctgaca atatctcttt
     2701 aaatagaagc tccgcgaggg ggataattga ctaaagtgtt tgcgacgtga aacggcggcg
     2761 cgcgggagtc gggagcccac acgagctgcg ggtccaggtt taaattatat caaactctgg
     2821 cgagagctgg aaggagcctg ttaaacggct cctgcttctc gctgggccgt taatggaggg
     2881 cagggcggat gatggatgct agagttcgag acccgggact cctgccttgg tcctaccgcg
     2941 tgggacgcag gcccggccca gttttattac tgggtagatg agtaagtcag aggcaaccgc
     3001 agagaggtgg tcagaggccc tttcctgaca ctgtcctttg tcccctgcct gctcgccccc
     3061 accctcctgc cctatactgg cctagcgagg cggcggggtt gggggcgggg gtccggcggg
     3121 acgggtgcgc taggaccttg cggaagcgcc agcacgtgtg tcagtgcgcc tggcccgcgg
     3181 ggaggcggca ggtggggctc ttttgtgaac cctgagggtg gaacttgaag cctttcacct
     3241 gcctgcagta aggtctttgc aagacttcga tctgtttgcc tttgcagtac ggaaggtttc
     3301 tcgccagcaa ctcccaggga actgcccaga gcgagaatgt gccgagatac tgctgggcct
     3361 ggcggtgagg ggtgggcggc caggagtggg cctcgtgcag gtgtcaggac acctatccag
     3421 tccttgccct ccgcttgccc ccatccgcta ggccaagcag gccggcgcac tggacgtgat
     3481 ctctggtgcc ccctggtggc agcgctgggc cctccccgct gcgccccggc tcggagctca
     3541 gacatcctgg ttttctttgg gatcacccct gtgtacttct tcatccatgt gcatttatcg
     3601 tggaatcctc ttcctcttgt agaatattaa atccggatac ttgaagtcac tttacagcag
     3661 tgaagtgagg gacaatgaac aaaaaactcg cattgagagt agcaggagcc cagacccttc
     3721 aataaggacc ccaagttaaa tcttccaagt taaggctgag agctacagct ctcttccgaa
     3781 aagctggagc tgccaaccct tcccttggga cctgccgatt atgcagtttt cttctgatac
     3841 tagctttggt ttctgaggta ttctgccctc tccctcccct cttctcccaa aacatctgcc
     3901 tctcctcagt ccccgtctgg gtggtgggtg cacaatacca agtgcctgaa aagcctgaga
     3961 gagagggtct ggggtagggt ggggaccact ggacacccca agtgcaaact gctgctttct
     4021 gacccttgct tgcttatgta ctcccttttc aactgtgttg aattttaatg acgtttttag
     4081 tggtgtagaa atgcaagtat tttggcttaa cagcatgaag tctgggttgc acattgtatc
     4141 agaggtgctg taatctttcc agtatctctg atatacggct ttctggttga atgtcaccct
     4201 gggccctctt gactggataa acaaccatga gggctcttct ctgtggagct gccgagagct
     4261 tggtggtaga aagcgatgtt tctaaacaac tgcagcggct ctttcctgtc tgaactgcat
     4321 cgtgtgtctg actgccttgc tgtccataca tacagactcc ttcccaggcc cggctctgtg
     4381 cagaacttcc atgttttacc acatttttct ctcctgaact ccctttgtca gccccagggt
     4441 gttgaggctg ggtcctctct agcaatctct accttcagaa gagacttttc taaatatttt
     4501 gcttttccag ttcttgttgc ttttgtcatt gtgaagagtc acccaggatg ctggcacttg
     4561 gtaccctaag atcagaagtg gtgtgtgtgt gagctgtgag acatgcacac cctttcagag
     4621 tgatactgtg tggtggaagg actgttagaa ctcaaagaat agttaataaa tccagtgtat
     4681 tattccgttg cga
//
