LOCUS       NM_001304369            3407 bp    mRNA    linear   PRI 12-JUN-2024
DEFINITION  Homo sapiens ankyrin repeat domain 60 (ANKRD60), mRNA.
ACCESSION   NM_001304369
VERSION     NM_001304369.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3407)
  AUTHORS   Bailey,S.D., Xie,C., Do,R., Montpetit,A., Diaz,R., Mohan,V.,
            Keavney,B., Yusuf,S., Gerstein,H.C., Engert,J.C. and Anand,S.
  CONSRTM   DREAM investigators
  TITLE     Variation at the NFATC2 locus increases the risk of
            thiazolidinedione-induced edema in the Diabetes REduction
            Assessment with ramipril and rosiglitazone Medication (DREAM) study
  JOURNAL   Diabetes Care 33 (10), 2250-2253 (2010)
   PUBMED   20628086
  REMARK    GeneRIF: Observational study of gene-disease association,
            gene-environment interaction, and pharmacogenomic / toxicogenomic.
            (HuGE Navigator)
REFERENCE   2  (bases 1 to 3407)
  AUTHORS   Kim,J.J., Lee,H.I., Park,T., Kim,K., Lee,J.E., Cho,N.H., Shin,C.,
            Cho,Y.S., Lee,J.Y., Han,B.G., Yoo,H.W. and Lee,J.K.
  TITLE     Identification of 15 loci influencing height in a Korean population
  JOURNAL   J Hum Genet 55 (1), 27-31 (2010)
   PUBMED   19893584
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   3  (bases 1 to 3407)
  AUTHORS   Talmud,P.J., Drenos,F., Shah,S., Shah,T., Palmen,J., Verzilli,C.,
            Gaunt,T.R., Pallas,J., Lovering,R., Li,K., Casas,J.P., Sofat,R.,
            Kumari,M., Rodriguez,S., Johnson,T., Newhouse,S.J., Dominiczak,A.,
            Samani,N.J., Caulfield,M., Sever,P., Stanton,A., Shields,D.C.,
            Padmanabhan,S., Melander,O., Hastie,C., Delles,C., Ebrahim,S.,
            Marmot,M.G., Smith,G.D., Lawlor,D.A., Munroe,P.B., Day,I.N.,
            Kivimaki,M., Whittaker,J., Humphries,S.E. and Hingorani,A.D.
  CONSRTM   ASCOT investigators; NORDIL investigators; BRIGHT Consortium
  TITLE     Gene-centric association signals for lipids and apolipoproteins
            identified via the HumanCVD BeadChip
  JOURNAL   Am J Hum Genet 85 (5), 628-642 (2009)
   PUBMED   19913121
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   4  (bases 1 to 3407)
  AUTHORS   Deloukas,P., Matthews,L.H., Ashurst,J., Burton,J., Gilbert,J.G.,
            Jones,M., Stavrides,G., Almeida,J.P., Babbage,A.K., Bagguley,C.L.,
            Bailey,J., Barlow,K.F., Bates,K.N., Beard,L.M., Beare,D.M.,
            Beasley,O.P., Bird,C.P., Blakey,S.E., Bridgeman,A.M., Brown,A.J.,
            Buck,D., Burrill,W., Butler,A.P., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M., Clark,G., Clark,L.N., Clark,S.Y.,
            Clee,C.M., Clegg,S., Cobley,V.E., Collier,R.E., Connor,R.,
            Corby,N.R., Coulson,A., Coville,G.J., Deadman,R., Dhami,P.,
            Dunn,M., Ellington,A.G., Frankland,J.A., Fraser,A., French,L.,
            Garner,P., Grafham,D.V., Griffiths,C., Griffiths,M.N., Gwilliam,R.,
            Hall,R.E., Hammond,S., Harley,J.L., Heath,P.D., Ho,S., Holden,J.L.,
            Howden,P.J., Huckle,E., Hunt,A.R., Hunt,S.E., Jekosch,K.,
            Johnson,C.M., Johnson,D., Kay,M.P., Kimberley,A.M., King,A.,
            Knights,A., Laird,G.K., Lawlor,S., Lehvaslaiho,M.H., Leversha,M.,
            Lloyd,C., Lloyd,D.M., Lovell,J.D., Marsh,V.L., Martin,S.L.,
            McConnachie,L.J., McLay,K., McMurray,A.A., Milne,S., Mistry,D.,
            Moore,M.J., Mullikin,J.C., Nickerson,T., Oliver,K., Parker,A.,
            Patel,R., Pearce,T.A., Peck,A.I., Phillimore,B.J.,
            Prathalingam,S.R., Plumb,R.W., Ramsay,H., Rice,C.M., Ross,M.T.,
            Scott,C.E., Sehra,H.K., Shownkeen,R., Sims,S., Skuce,C.D.,
            Smith,M.L., Soderlund,C., Steward,C.A., Sulston,J.E., Swann,M.,
            Sycamore,N., Taylor,R., Tee,L., Thomas,D.W., Thorpe,A., Tracey,A.,
            Tromans,A.C., Vaudin,M., Wall,M., Wallis,J.M., Whitehead,S.L.,
            Whittaker,P., Willey,D.L., Williams,L., Williams,S.A., Wilming,L.,
            Wray,P.W., Hubbard,T., Durbin,R.M., Bentley,D.R., Beck,S. and
            Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 20
  JOURNAL   Nature 414 (6866), 865-871 (2001)
   PUBMED   11780052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL354776.15.
            
            On Jun 24, 2021 this sequence version replaced NM_001304369.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000457363.2/ ENSP00000396747.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-430               AL354776.15        115109-115538       c
            431-561             AL354776.15        109937-110067       c
            562-727             AL354776.15        108223-108388       c
            728-3407            AL354776.15        103011-105690       c
FEATURES             Location/Qualifiers
     source          1..3407
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20q13.32"
     gene            1..3407
                     /gene="ANKRD60"
                     /gene_synonym="bA196N14.3; C20orf86"
                     /note="ankyrin repeat domain 60"
                     /db_xref="GeneID:140731"
                     /db_xref="HGNC:HGNC:16217"
     CDS             1..1038
                     /gene="ANKRD60"
                     /gene_synonym="bA196N14.3; C20orf86"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein 60"
                     /protein_id="NP_001291298.1"
                     /db_xref="CCDS:CCDS77596.1"
                     /db_xref="GeneID:140731"
                     /db_xref="HGNC:HGNC:16217"
                     /translation="MTRGRAWGMRRAAAGAGGARAAGPTGGASRLHPNAGRRSGARAG
                     AQGCGGPRVGSADSRALPAQPLACARGRSQRLVCDPKAASALPDLAPDVFVLRVRLEE
                     TGEMFRVANCRGDMTVRELKEELDLMVGIPFNLQRLQYLDEGVLMDDTTLKFHDVVPG
                     GIISLCIWHHDGWTELVLAAVEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQ
                     RAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG
                     ASIHDRDAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLNDLVMKNALQRVKSG
                     FRSEKMTMTPH"
     exon            1..430
                     /gene="ANKRD60"
                     /gene_synonym="bA196N14.3; C20orf86"
                     /inference="alignment:Splign:2.1.0"
     exon            431..561
                     /gene="ANKRD60"
                     /gene_synonym="bA196N14.3; C20orf86"
                     /inference="alignment:Splign:2.1.0"
     exon            562..727
                     /gene="ANKRD60"
                     /gene_synonym="bA196N14.3; C20orf86"
                     /inference="alignment:Splign:2.1.0"
     exon            728..3407
                     /gene="ANKRD60"
                     /gene_synonym="bA196N14.3; C20orf86"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgacgcgcg gccgcgcctg ggggatgcgg cgggcggcgg cgggggcggg cggagcgcgg
       61 gcggcggggc caactggggg cgcctctcgc ctgcacccca atgcgggacg caggagcggt
      121 gcgcgggccg gggctcaggg gtgcggcggg cccagggtgg gctcggcgga ctcgcgggcc
      181 ctccccgcgc agcccctggc ctgtgcccgc ggccggagcc agcggctcgt ctgtgacccg
      241 aaggccgcga gtgccttgcc cgacttggcc cctgacgtct tcgtcctgcg ggtgcggctg
      301 gaggagacgg gggagatgtt ccgagtggca aactgccgcg gcgacatgac cgtgcgggag
      361 ctcaaagagg agctggacct gatggtcggc atccccttca acctccagcg gctccagtac
      421 ctcgacgaag gagttttgat ggatgacact accctgaagt tccatgatgt tgttcctgga
      481 gggattattt cattatgtat ctggcatcat gacggatgga cagaacttgt tttggcggct
      541 gtggaagggg atcccagcaa gctatcttgt ctcgggctta ctgaagattc cttctaccga
      601 accgcaaatt cagaacattt tgagggtgag aagtggaagc actggacgtc tcagagggcg
      661 tttgtggcgt tgtatgtggc ctcacacaga ggccactttg atgctgtgca gtaccttcta
      721 gaacacggag ccagctgcct cagcagatcc cccctgggca ggacacccct gcatgtggct
      781 gcagctatgg gccggtcaga ctgtataatc ctcctgctcc agcacggggc ctccatccac
      841 gacagagatg ccaaggggga gacccccatc tccattgcac accgcctgaa ccacacactg
      901 agcgagaggc agatggtcct cctccaccgg atagcaaagt cggggataag ggatctgaat
      961 gacttggtca tgaagaatgc tttgcagagg gtcaagtctg ggtttaggtc tgagaagatg
     1021 acgatgaccc ctcattagct cctggtggga acgtttgccc gctgaggctg gtttgggcaa
     1081 ctttgcagag ttcaatccca tgggggccct tggtgagcag ggaggcagga aaacagggca
     1141 attaacctga atcagatacg aaattatctg tcctgtttgc aaatgatttc tggagggtgt
     1201 tgatggcagt aggtaagcct gtgctcattt agtaatccat tacagactga acaggctcta
     1261 atgccagcct ttaattttaa gctatttgca cattgtaccc aatagcgctg ctcagggtga
     1321 tgggagccaa ttaccttctc tcccttctgg ggaccgtcta atgcactggc ataataggag
     1381 taataacaat aatgataata gcactattgt tattgtataa aacaagtgcc agcaaatgtc
     1441 aggaggtcgt gtgtagtgtg ggctgtgaat ttcagtctgt aaagccatgg aactaaatgc
     1501 tcccacagct aatgttccag gtttcctgag ccatctttga ggggtctgct tcttgagtcg
     1561 ggggcagaag ggaagctggg tgagcttggc tgtccacaca cactctccag aagggatggc
     1621 ttattactct tgttgaaagg taacacgttg gtgctagatg gggaggaaac agtgtaaaag
     1681 aagatgagaa tcaggctggt cacattttct cttttgtccc atctccagtg gtccatgcag
     1741 tctcctcttg ccagagttct ccttttcctg ccagcactgg gatagccctt ccttctttcc
     1801 tttgagcaaa ccaccttgga gtgtctatgc tcaactctca ggtctttgca ttgcaaaacc
     1861 ttataccgca ttgcaggatg tgcctggtgt tcctacaggg tcccagcctg ccgagtgcac
     1921 gagtgagctg ggcgtgggaa ataagaagga aagacaagga tggcgccagc tgtctgaaga
     1981 gagcaccgag acttgactcc tgcagaaatg aaaggcagag gccactagat ctttctagaa
     2041 ctctccagac ctggaaatct ggctttttga aaggatctcc cttgattttt ttttttcttt
     2101 ttttgagaca gagtcttgct ctattgccca ggctggagtg cagtggtgcc atctcggctc
     2161 actgcaacct ctgcctcctg ggttcaagcg attctcctgc ctcagcctct tgagtagcta
     2221 agattacagg cacctgccac catgcctggc taatttttgt atttttagta gagatggggt
     2281 ttcaccacgt tggccaggtt ggtctcgaac tcctgacctc atgatctgcc cccctcggcc
     2341 tcccaaagtg ttggatttac aggcatgagc caccacaccc ggccagatct ctcttgattt
     2401 ttaaaatttg gcttgaattt ttgaagaacg tggtctgcta caaaaggagt gagaagatgt
     2461 ggggcacacc catgtgactg cctctcactg tcaaactcta attcatttca tggagaaacg
     2521 tgatagaaac aaccaaaatc tctctggagc aatccaagac tctgatgcca cagtgaagga
     2581 gtagccacgg gtcttactgg gtggcgtgtg gggtccactc tcccacctcc cacagaccat
     2641 ttatgttctc taaagctcta ccttctaagc aacttttgga atcaaaatgt gtggcagtag
     2701 tcttgtgacc attgcagttt tcctgggaat gggaaatggc gctgtatcct ggccaccctt
     2761 tcccacttcc atcccaagaa ctggagtcag cttttaaatt aactggctgc atttcctgct
     2821 gtcatagcaa gtaagatctg tgttgatgat gtggttttac actcagtgta cgtggctgta
     2881 cccagctcag cactctgtta gacaaataat agtcgaggaa aaaaatagct cagcatcaac
     2941 tatgtcaaaa ctgagatctt gttcttggca gacgttctgc aaagtcaata ggcagatatt
     3001 aagcaacccc aacccaatgg ggcaatccat ttagctaatg aagtgttagg ggggtgatgc
     3061 aggcactctt ttaacttaac aagtggcatt actcaaagtt gtgcatttgc caggagctct
     3121 gcccagctgc cttcgttgtt tggagagcca actgcttgac tcctatatgt aaaattctgg
     3181 gggcaagcat tctatcttca tctaccccca attcaattaa gcacttggcc agacattggg
     3241 caggtcccaa actcttcatg gtgacatttt gctcagtctg tggtagggtc atctgaacac
     3301 tcgtaggtcc tggggagcgc ttcattttag acaatcctga cattctattt atattcaaca
     3361 agtctgtatc acttacgaaa taaaatatat ccagagccat agaagga
//
