LOCUS       NM_001358683             832 bp    mRNA    linear   PRI 15-FEB-2024
DEFINITION  Homo sapiens ANKRD40 C-terminal like (ANKRD40CL), transcript
            variant 2, mRNA.
ACCESSION   NM_001358683 NR_073199 XR_158917 XR_159289
VERSION     NM_001358683.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 832)
  AUTHORS   Qiao,Y.S., Zhou,J.H., Jin,B.H., Wu,Y.Q. and Zhao,B.
  TITLE     LINC00483 is regulated by IGF2BP1 and participates in the
            progression of breast cancer
  JOURNAL   Eur Rev Med Pharmacol Sci 25 (3), 1379-1386 (2021)
   PUBMED   33629308
  REMARK    GeneRIF: LINC00483 is regulated by IGF2BP1 and participates in the
            progression of breast cancer.
REFERENCE   2  (bases 1 to 832)
  AUTHORS   Hu,P., Zhou,G., Zhang,X., Song,G., Zhan,L. and Cao,Y.
  TITLE     Long non-coding RNA Linc00483 accelerated tumorigenesis of cervical
            cancer by regulating miR-508-3p/RGS17 axis
  JOURNAL   Life Sci 234, 116789 (2019)
   PUBMED   31454494
  REMARK    GeneRIF: Knock-down of Long non-coding RNA Linc00483 inhibited the
            development of cervical cancer by regulating miR-508-3p/RGS17 axis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK310037.1, BP382918.1, AK000701.1 and AC005921.3.
            
            On Feb 27, 2020 this sequence version replaced NM_001358683.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BP382918.1, SRR14243140.7988220.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2153733 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000450727.6/ ENSP00000494384.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-354               AK310037.1         40-393
            355-391             BP382918.1         352-388
            392-554             AK000701.1         2324-2486
            555-572             AC005921.3         94706-94723         c
            573-828             AK000701.1         2505-2760
            829-832             AC005921.3         94446-94449         c
FEATURES             Location/Qualifiers
     source          1..832
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.33"
     gene            1..832
                     /gene="ANKRD40CL"
                     /gene_synonym="C17orf73; LINC00483"
                     /note="ANKRD40 C-terminal like"
                     /db_xref="GeneID:55018"
                     /db_xref="HGNC:HGNC:26080"
     exon            1..56
                     /gene="ANKRD40CL"
                     /gene_synonym="C17orf73; LINC00483"
                     /inference="alignment:Splign:2.1.0"
     exon            57..194
                     /gene="ANKRD40CL"
                     /gene_synonym="C17orf73; LINC00483"
                     /inference="alignment:Splign:2.1.0"
     CDS             155..499
                     /gene="ANKRD40CL"
                     /gene_synonym="C17orf73; LINC00483"
                     /note="isoform 2 is encoded by transcript variant 2; long
                     intergenic non-protein coding RNA 483; putative ANKRD40
                     C-terminal-like protein"
                     /codon_start=1
                     /product="putative ANKRD40 C-terminal-like protein isoform
                     2"
                     /protein_id="NP_001345612.1"
                     /db_xref="CCDS:CCDS86616.1"
                     /db_xref="GeneID:55018"
                     /db_xref="HGNC:HGNC:26080"
                     /translation="MAEPEQDIGEKPAVRIQNPKENDFIEIELKRQELSYQNLLNVSC
                     CELGIKPERVEKIRKLPNTLLRKDKDIRRLRDFQEVELILMKNGSSRLTEYVPSLTER
                     PCYDSKAAKMTY"
     exon            195..355
                     /gene="ANKRD40CL"
                     /gene_synonym="C17orf73; LINC00483"
                     /inference="alignment:Splign:2.1.0"
     exon            356..832
                     /gene="ANKRD40CL"
                     /gene_synonym="C17orf73; LINC00483"
                     /inference="alignment:Splign:2.1.0"
     regulatory      816..821
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANKRD40CL"
                     /gene_synonym="C17orf73; LINC00483"
                     /note="hexamer: AATAAA"
     polyA_site      832
                     /gene="ANKRD40CL"
                     /gene_synonym="C17orf73; LINC00483"
                     /note="major polyA site"
ORIGIN      
        1 cattttgatg tctagaatca ggggatccag gatcatcacc aaggtcattt tcccagacag
       61 atgtgctgag gctgtagaaa gtgcttttta tttggttggg agcttgtgca taaatgcgag
      121 aggggctgca catctgacgg actagaggtg actcatggct gaaccggaac aggacatcgg
      181 ggagaagcca gcagtcagaa ttcagaaccc caaagaaaat gacttcattg aaattgaact
      241 gaagagacaa gaactgagtt accaaaacct actaaacgtg agttgctgtg aactggggat
      301 taaaccagaa cgagtggaga agatcagaaa gctaccaaac acactgctca gaaaggacaa
      361 agacattcga agactgcggg actttcagga agtggaactc attttaatga aaaatggaag
      421 ctccagattg acagaatatg tgccatctct gacagaaagg ccctgctatg atagcaaagc
      481 tgcaaaaatg acttattaaa tactcccagg aatggccgcg catggtggct caccccctgt
      541 aatcccagca ctttaggaag ccaaggtggg cagatcacct gaggtcagga gttctagacc
      601 agcctggcca acatatagtg aaacccagtc tctactaaaa aaaatacaaa aattagctag
      661 gtgtggtggc gcacacctgt agtagtccca gctacatggg aagctgaggc aggagaatca
      721 cctgaaccca ggaggcagag gttgcagtga gctgagattg cgccactgca ctccagcctg
      781 gcgacagagc aagactctgt ctctcaaaat aaataaataa ataaataatc aa
//
