LOCUS       NM_001146341            5506 bp    mRNA    linear   PRI 06-APR-2024
DEFINITION  Homo sapiens ankyrin repeat domain 34C (ANKRD34C), mRNA.
ACCESSION   NM_001146341 XM_001719889 XM_930512 XM_939324
VERSION     NM_001146341.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5506)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 5506)
  AUTHORS   Ota,T., Suzuki,Y., Nishikawa,T., Otsuki,T., Sugiyama,T., Irie,R.,
            Wakamatsu,A., Hayashi,K., Sato,H., Nagai,K., Kimura,K., Makita,H.,
            Sekine,M., Obayashi,M., Nishi,T., Shibahara,T., Tanaka,T.,
            Ishii,S., Yamamoto,J., Saito,K., Kawai,Y., Isono,Y., Nakamura,Y.,
            Nagahari,K., Murakami,K., Yasuda,T., Iwayanagi,T., Wagatsuma,M.,
            Shiratori,A., Sudo,H., Hosoiri,T., Kaku,Y., Kodaira,H., Kondo,H.,
            Sugawara,M., Takahashi,M., Kanda,K., Yokoi,T., Furuya,T.,
            Kikkawa,E., Omura,Y., Abe,K., Kamihara,K., Katsuta,N., Sato,K.,
            Tanikawa,M., Yamazaki,M., Ninomiya,K., Ishibashi,T., Yamashita,H.,
            Murakawa,K., Fujimori,K., Tanai,H., Kimata,M., Watanabe,M.,
            Hiraoka,S., Chiba,Y., Ishida,S., Ono,Y., Takiguchi,S., Watanabe,S.,
            Yosida,M., Hotuta,T., Kusano,J., Kanehori,K., Takahashi-Fujii,A.,
            Hara,H., Tanase,T.O., Nomura,Y., Togiya,S., Komai,F., Hara,R.,
            Takeuchi,K., Arita,M., Imose,N., Musashino,K., Yuuki,H., Oshima,A.,
            Sasaki,N., Aotsuka,S., Yoshikawa,Y., Matsunawa,H., Ichihara,T.,
            Shiohata,N., Sano,S., Moriya,S., Momiyama,H., Satoh,N., Takami,S.,
            Terashima,Y., Suzuki,O., Nakagawa,S., Senoh,A., Mizoguchi,H.,
            Goto,Y., Shimizu,F., Wakebe,H., Hishigaki,H., Watanabe,T.,
            Sugiyama,A., Takemoto,M., Kawakami,B., Yamazaki,M., Watanabe,K.,
            Kumagai,A., Itakura,S., Fukuzumi,Y., Fujimori,Y., Komiyama,M.,
            Tashiro,H., Tanigami,A., Fujiwara,T., Ono,T., Yamada,K., Fujii,Y.,
            Ozaki,K., Hirao,M., Ohmori,Y., Kawabata,A., Hikiji,T., Kobatake,N.,
            Inagaki,H., Ikema,Y., Okamoto,S., Okitani,R., Kawakami,T.,
            Noguchi,S., Itoh,T., Shigeta,K., Senba,T., Matsumura,K.,
            Nakajima,Y., Mizuno,T., Morinaga,M., Sasaki,M., Togashi,T.,
            Oyama,M., Hata,H., Watanabe,M., Komatsu,T., Mizushima-Sugano,J.,
            Satoh,T., Shirai,Y., Takahashi,Y., Nakagawa,K., Okumura,K.,
            Nagase,T., Nomura,N., Kikuchi,H., Masuho,Y., Yamashita,R.,
            Nakai,K., Yada,T., Nakamura,Y., Ohara,O., Isogai,T. and Sugano,S.
  TITLE     Complete sequencing and characterization of 21,243 full-length
            human cDNAs
  JOURNAL   Nat Genet 36 (1), 40-45 (2004)
   PUBMED   14702039
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC011797.8, AK127037.1, AK090665.1 and AL109678.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001146341.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660805.232160.1,
                                           SRR1803614.69396.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2153347, SAMEA2154665
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000421388.4/ ENSP00000401089.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-82                AC011797.8         120497-120578
            83-944              AK127037.1         1-862
            945-3698            AC011797.8         131453-134206
            3699-5501           AK090665.1         1-1803
            5502-5506           AL109678.1         1404-1408
FEATURES             Location/Qualifiers
     source          1..5506
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q25.1"
     gene            1..5506
                     /gene="ANKRD34C"
                     /note="ankyrin repeat domain 34C"
                     /db_xref="GeneID:390616"
                     /db_xref="HGNC:HGNC:33888"
     exon            1..507
                     /gene="ANKRD34C"
                     /inference="alignment:Splign:2.1.0"
     exon            508..5506
                     /gene="ANKRD34C"
                     /inference="alignment:Splign:2.1.0"
     CDS             552..2159
                     /gene="ANKRD34C"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein 34C"
                     /protein_id="NP_001139813.1"
                     /db_xref="CCDS:CCDS53965.1"
                     /db_xref="GeneID:390616"
                     /db_xref="HGNC:HGNC:33888"
                     /translation="MMDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKG
                     ETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVV
                     SLLLENGADPSLEDRTGASALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSG
                     TKTTKQYLNVPPSPKVEDRHSPPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPS
                     SCNTSKAVNEPGSPTRKVSNLKRARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGAS
                     TDNEVIKSISDISFPKRGPLSRTNSIDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYE
                     KGQAPHPRLARRGTLPVDQEKCGMGPSGPSALKEPASLKWLENDLYDLDIQPGPDPPN
                     SISLESGKGPLDRKKLNSSHLSLFHGSRESLDTVPSTSPSSARRRPPHLLERRGSGTL
                     LLDRISHTRPGFLPPLNVNLNPPIPDIRSSSKPSCSLASGLKSMVPVAPSSPKRVDLR
                     SKKKLLRRHSMQIEQMKQLSDFEEIMT"
     regulatory      5481..5486
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANKRD34C"
                     /note="hexamer: AATAAA"
     polyA_site      5506
                     /gene="ANKRD34C"
                     /note="major polyA site"
ORIGIN      
        1 acacaaccct cgcccgtcgc ggctggagag ctgctctcgg cgccagcggg cagcagcgcg
       61 tcgtcagcca gcacagccgg ccgaagacca agccggaggt ctggggctgc gcagagacct
      121 gcacacccgc agcgcggaac cgggggcgat tcctatcttt ctttcatgct tctttctttt
      181 tcttaaaacc aaaccaaacc aaaccaaacc caaaactccc ctgctcccac cgcaacttgg
      241 aggagcggtg gaccgatttg aaggaactga cgcagaggtt ttattcacga accttgaaga
      301 agttctgggc aagtgactca acaggacccg cggggcccgg ggtagcccca gctcccggcg
      361 ctggttcagt ctggcagtgc cctctggcag ccaacccgca gctgcaggta ggggtgctgg
      421 acgccccctg attttgtttt gggaataata atgacactac ctatagcctg gacccaggtg
      481 gcctcgctcg gcgattgtcc ccaccaggtt tgattgctac tgtggctcag gtcctctaaa
      541 ctgtagccaa tatgatggat gatgacactg aattaaggac tgatggaaac tctttgttaa
      601 aggctgtgtg gctggggagg ctcaggttga ccaggctgct cttggaaggg ggagcttata
      661 tcaatgaaag caatgacaaa ggcgaaacag ctctcatggt ggcgtgcatc accaaacatg
      721 tggaccagca aagcatcagc aagtccaaga tggtgaagta cctgctggac aacagggcag
      781 accccaatat ccaagataag tctggcaaga ctgccctcat ccatgcctgt atcagaagag
      841 ctgggggaga agtggtctcc ttattactgg agaatggagc agaccccagc cttgaagatc
      901 gcactggggc ttcagctctg gtttatgcaa taaatgcaga tgacaaggat gcattgaagc
      961 atctccttga tgcctgcaaa gccaaaggga aggaggtgat tattataaca acagataaat
     1021 cgtcttcagg caccaaaacc accaaacagt atcttaatgt ccctccttca cccaaagtag
     1081 aagacaggca ttcacctcca ctgtgtgcgt ctccctctga catagagctg aaggctctag
     1141 gcctggactc tccactcact gagaaggaag atgacttctt cagcctccaa gcagggcatc
     1201 caagcagttg taacacctcc aaggctgtta atgagcctgg gtcacccacc aggaaagtca
     1261 gtaatctcaa aagggcccgt ttgcctcaac tgaagaggct ccagtctgaa ccttggggcc
     1321 tgatagcgcc ctcggtgctg gcagcctcga cgcgtcagga tgagacccat ggtgccagca
     1381 cagacaacga ggtcatcaag agcatcagtg atatatcctt ccctaaaagg gggcccctct
     1441 ccagaaccaa cagtatcgat agcaaagacc ccaccctctt tcacacagtc acagagcagg
     1501 ttctgaagat tccagtctct tcagcaccgg catcctggaa agcagcctat gagaaaggtc
     1561 aggctcccca cccacgtctg gccaggagag gaactctccc tgttgaccaa gagaaatgtg
     1621 gtatgggtcc atcaggaccc tctgctctca aagagcctgc atccctcaaa tggctggaaa
     1681 atgacctcta tgacttagat atacagccag ggcctgaccc tcccaactcc atttcccttg
     1741 aatccggcaa aggaccttta gatagaaaga agctcaacag ctctcacttg tctcttttcc
     1801 atggctctcg ggagtccctg gacactgtac ctagcacatc ccccagctca gcacgccgca
     1861 ggccgccaca tcttctagaa cgacgaggtt ctggaactct gctccttgat cgcatttctc
     1921 acactaggcc tggcttcctg ccgcctttaa atgtgaatct gaacccgcct attccagata
     1981 ttagatctag cagcaaacct tcttgctctc ttgctagtgg cttaaaatct atggttcctg
     2041 ttgctccaag ttcaccaaag agagttgact taagaagtaa aaagaagctc ctcagaaggc
     2101 attctatgca aattgaacaa atgaaacagc tgtctgattt tgaagaaatc atgacctaga
     2161 agctttagaa aggcttaaaa tagtcaatat agtttatgga agggactatg gatgagactg
     2221 cttcctgatc attccttaat gttgaactgt ggccacttca gaagatataa aagcaggatg
     2281 ctgcttcact tctgagaata atccctgggt ttttataggc ctacttgaaa agagctcagg
     2341 ataattgggt tttgaagata aatttttaaa aattctgcaa aggaagaaag cctttggaat
     2401 ttgaaggtaa cacagcaagt acaatgatgt aagctgggga catcagtagt tttctatcag
     2461 acaaacagaa aagaatttaa atcaggaggt agtatttgga gtatgtcatt tgtaataaat
     2521 ctataaagtg cctacataga aaacgaggct ttaacatttg ttagaatgta caaaagcccc
     2581 aaaccaaacc ctcagtgact aaatctgggt gtctgggttc tatctgatgg agtagaagca
     2641 gaattccccc catggaagag gctctggcct gtgggtcctg gctctgactc tgtcagggca
     2701 ctgtaaatca tggtgtggtt gaactcgttc agtaatccag taatatattt tgttcacata
     2761 ctaatttgta tgtgctctga gtacccaaat atcccatcta tgtggcccct gaattatgat
     2821 atgtcatagt agctgatgcc ttagagataa atcttgctcc agaaatgaaa ctttccccag
     2881 acccgtcccc tgacacaggc tcttgtattg aaatcttgtg aaaaacagtc aaggttaact
     2941 aacttggagt tgaatgtgat acaattatag attaaaaata tcagaagcat ttccagatta
     3001 ttcttaaaag ttgatgagat cttcccaaac cagaatgaca actgaggatg agatgtgcat
     3061 agattaaatg gtaaagtggg tggttctcag gtgagaagca gtgaggacca ttcattttgc
     3121 agcctaaaaa ttttagggga tgcaaactgt catttcccct tcagttatgt aaataattga
     3181 agaaaaatct ggtttcttct cttcctgatc tatctaggtg agaagagatt tgtagaaata
     3241 acctgcacaa cccttttagg ctgctttgag caaatccaag aaggaaagca gagacttagc
     3301 acatttggta taatgtagcc acatcttaga tgaatatatt tttggttatt tccatttatg
     3361 tttcctctcg tgctgctgag atctatttgc tctatggtta aaaagttcaa tagttcctga
     3421 ggacagcatc atatagagga aagagggctt tgagtctgac atatttgggt ttgcatacca
     3481 gtcttatcat ttaccagctg cgtgaccttg aggaggcagc ttaacttctc ttagtctctg
     3541 ttccctcatc tgtaaaatag gattagtagt gctgcacctt acaaggttgt gatgagaatt
     3601 aaatgacaca atgtatgaaa gtgctgccat tgtgcctggc acaggtagaa gtcactggat
     3661 aagaagtagc taattttaat gtatttcttg agactgctga agcaatatct caaataatac
     3721 atacgctaca caaaatggaa taaagtttct ctggaaaagt tcaagtatct ctatgagatc
     3781 cccagttatt tttataagta ccgatctcta aactcatgtg taaagtaaaa aattctgcca
     3841 tataaactct acatattata taatttttct ataactacct ttgctagaaa tttatctgaa
     3901 tattccaaac aaaagtgtta atgatggtta aacaaaaaaa ctcggtgttg tttggagggc
     3961 tgtctgtcct gtgtgttgta ggatgtttag cagcatctct ggcctccact cactagatgg
     4021 cagtaacacc ctctccccag ttgtgacaac caaaaatgtc tctagacgtg gccagatgtc
     4081 tcctgggtgc atcaccttcg ttgatctcta ctgctagacc tatcgtatat gtcaagaaca
     4141 acaaagctgt atggaaatgt gagtgctgac tggacagcta tgccctcctg ttaacttaag
     4201 acaattcaaa ttgtgcttta gtaagaggac taatcaatac tagtgttggg ccttcaggat
     4261 tcttggcaaa cacactccaa catgtgtgct aatggtctca tactttgtag gaagggaaga
     4321 aaataaggaa agcacataaa ctagcaaaaa tctatagctc atgaacttgg tttagtgtgg
     4381 acaaccctgt tcttttcaga actatttaat cattaatagt tcttaccaag tagaagtgat
     4441 cccaggcaaa gaaacaactt tccaatgcat tcaagagaga atcatacgga caaccatcat
     4501 tctcagcagc tcattaaatg caaatacaca cacgcaaaga gagagagaga acacatttta
     4561 catagttttc cagctgttgt tagtgtcact taaaactgat ctctgctggt agtattcagt
     4621 tgtgagtata gcaagacact gcataggagc attttttttc taaaccttta gctaagattt
     4681 ggaaacccaa tatttcctaa gtagtgaatg tggtctattt atagtaatta gcttaggtga
     4741 cacaccaaac atgatgagtt gctcattcag gatagccggt ccattgcaca aatgtgtaat
     4801 atcaggtact ctcatgccac tcattgcctg catcagtcag tcatgacctt tgcatcagcc
     4861 tttcaataga cagtcatcag gctagtatct tatctcatca ctacttgacg atgagttcgc
     4921 cgaattagac tgttctatac cagtacaaca accaaaatac tttctcatag attatgcata
     4981 aatacgcaat tttgtccatg tcaatgaacc taacaagaat gctttttaaa agtatatttt
     5041 agattcaaac atgctttcta gatcagaggt taacttgtct ttttgaaatc ctggagtcac
     5101 ttataagtta gctgcaaact gtagtttcgg taattcaact gcttaagcat ttctggactg
     5161 tttatcaaaa tatattacag aatgtgagac taaagtttaa agtctggacc tttggtttaa
     5221 tttctagact ttccaaagct tttttttttc tttttaaaaa gcccattgtc aactctctta
     5281 gaacttcatc aagtaaatgg taccttgcaa atgtaggttg tgtctgacct tctttctttt
     5341 tgtgtgttgg tgcctcagat gtatcatgtg ctgcttgaac tgattctcta cagtgttcct
     5401 tcctagtctc aagctgatga tgtgctcaaa gatgtatcaa aatccatgta atgacacctt
     5461 ttagatgttt ctaatatgtc aataaatgat atattgcaat ccttca
//
