LOCUS       NM_001039888            3607 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens ankyrin repeat domain 34A (ANKRD34A), mRNA.
ACCESSION   NM_001039888 XM_927841 XM_936326
VERSION     NM_001039888.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3607)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 3607)
  AUTHORS   Barbe,L., Lundberg,E., Oksvold,P., Stenius,A., Lewin,E.,
            Bjorling,E., Asplund,A., Ponten,F., Brismar,H., Uhlen,M. and
            Andersson-Svahn,H.
  TITLE     Toward a confocal subcellular atlas of the human proteome
  JOURNAL   Mol Cell Proteomics 7 (3), 499-508 (2008)
   PUBMED   18029348
REFERENCE   3  (bases 1 to 3607)
  AUTHORS   Kimura,K., Wakamatsu,A., Suzuki,Y., Ota,T., Nishikawa,T.,
            Yamashita,R., Yamamoto,J., Sekine,M., Tsuritani,K., Wakaguri,H.,
            Ishii,S., Sugiyama,T., Saito,K., Isono,Y., Irie,R., Kushida,N.,
            Yoneyama,T., Otsuka,R., Kanda,K., Yokoi,T., Kondo,H., Wagatsuma,M.,
            Murakawa,K., Ishida,S., Ishibashi,T., Takahashi-Fujii,A.,
            Tanase,T., Nagai,K., Kikuchi,H., Nakai,K., Isogai,T. and Sugano,S.
  TITLE     Diversification of transcriptional modulation: large-scale
            identification and characterization of putative alternative
            promoters of human genes
  JOURNAL   Genome Res 16 (1), 55-65 (2006)
   PUBMED   16344560
REFERENCE   4  (bases 1 to 3607)
  AUTHORS   Ota,T., Suzuki,Y., Nishikawa,T., Otsuki,T., Sugiyama,T., Irie,R.,
            Wakamatsu,A., Hayashi,K., Sato,H., Nagai,K., Kimura,K., Makita,H.,
            Sekine,M., Obayashi,M., Nishi,T., Shibahara,T., Tanaka,T.,
            Ishii,S., Yamamoto,J., Saito,K., Kawai,Y., Isono,Y., Nakamura,Y.,
            Nagahari,K., Murakami,K., Yasuda,T., Iwayanagi,T., Wagatsuma,M.,
            Shiratori,A., Sudo,H., Hosoiri,T., Kaku,Y., Kodaira,H., Kondo,H.,
            Sugawara,M., Takahashi,M., Kanda,K., Yokoi,T., Furuya,T.,
            Kikkawa,E., Omura,Y., Abe,K., Kamihara,K., Katsuta,N., Sato,K.,
            Tanikawa,M., Yamazaki,M., Ninomiya,K., Ishibashi,T., Yamashita,H.,
            Murakawa,K., Fujimori,K., Tanai,H., Kimata,M., Watanabe,M.,
            Hiraoka,S., Chiba,Y., Ishida,S., Ono,Y., Takiguchi,S., Watanabe,S.,
            Yosida,M., Hotuta,T., Kusano,J., Kanehori,K., Takahashi-Fujii,A.,
            Hara,H., Tanase,T.O., Nomura,Y., Togiya,S., Komai,F., Hara,R.,
            Takeuchi,K., Arita,M., Imose,N., Musashino,K., Yuuki,H., Oshima,A.,
            Sasaki,N., Aotsuka,S., Yoshikawa,Y., Matsunawa,H., Ichihara,T.,
            Shiohata,N., Sano,S., Moriya,S., Momiyama,H., Satoh,N., Takami,S.,
            Terashima,Y., Suzuki,O., Nakagawa,S., Senoh,A., Mizoguchi,H.,
            Goto,Y., Shimizu,F., Wakebe,H., Hishigaki,H., Watanabe,T.,
            Sugiyama,A., Takemoto,M., Kawakami,B., Yamazaki,M., Watanabe,K.,
            Kumagai,A., Itakura,S., Fukuzumi,Y., Fujimori,Y., Komiyama,M.,
            Tashiro,H., Tanigami,A., Fujiwara,T., Ono,T., Yamada,K., Fujii,Y.,
            Ozaki,K., Hirao,M., Ohmori,Y., Kawabata,A., Hikiji,T., Kobatake,N.,
            Inagaki,H., Ikema,Y., Okamoto,S., Okitani,R., Kawakami,T.,
            Noguchi,S., Itoh,T., Shigeta,K., Senba,T., Matsumura,K.,
            Nakajima,Y., Mizuno,T., Morinaga,M., Sasaki,M., Togashi,T.,
            Oyama,M., Hata,H., Watanabe,M., Komatsu,T., Mizushima-Sugano,J.,
            Satoh,T., Shirai,Y., Takahashi,Y., Nakagawa,K., Okumura,K.,
            Nagase,T., Nomura,N., Kikuchi,H., Masuho,Y., Yamashita,R.,
            Nakai,K., Yada,T., Nakamura,Y., Ohara,O., Isogai,T. and Sugano,S.
  TITLE     Complete sequencing and characterization of 21,243 full-length
            human cDNAs
  JOURNAL   Nat Genet 36 (1), 40-45 (2004)
   PUBMED   14702039
REFERENCE   5  (bases 1 to 3607)
  AUTHORS   Bonaldo,M.F., Lennon,G. and Soares,M.B.
  TITLE     Normalization and subtraction: two approaches to facilitate gene
            discovery
  JOURNAL   Genome Res 6 (9), 791-806 (1996)
   PUBMED   8889548
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK128050.1, AC243547.1, DA081864.1 and BM723295.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001039888.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK128050.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2142348, SAMEA2153946
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000606888.3/ ENSP00000475189.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-948               AK128050.1         8-955
            949-1133            AC243547.1         72580-72764
            1134-1675           DA081864.1         1-542
            1676-3201           AK128050.1         1677-3202
            3202-3607           BM723295.1         73-478
FEATURES             Location/Qualifiers
     source          1..3607
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q21.1"
     gene            1..3607
                     /gene="ANKRD34A"
                     /gene_synonym="ANKRD34"
                     /note="ankyrin repeat domain 34A"
                     /db_xref="GeneID:284615"
                     /db_xref="HGNC:HGNC:27639"
     exon            1..392
                     /gene="ANKRD34A"
                     /gene_synonym="ANKRD34"
                     /inference="alignment:Splign:2.1.0"
     exon            393..620
                     /gene="ANKRD34A"
                     /gene_synonym="ANKRD34"
                     /inference="alignment:Splign:2.1.0"
     exon            621..1168
                     /gene="ANKRD34A"
                     /gene_synonym="ANKRD34"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..3607
                     /gene="ANKRD34A"
                     /gene_synonym="ANKRD34"
                     /inference="alignment:Splign:2.1.0"
     CDS             1289..2779
                     /gene="ANKRD34A"
                     /gene_synonym="ANKRD34"
                     /note="ankyrin repeat domain 34"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein 34A"
                     /protein_id="NP_001034977.1"
                     /db_xref="CCDS:CCDS72874.1"
                     /db_xref="GeneID:284615"
                     /db_xref="HGNC:HGNC:27639"
                     /translation="MLHTEGHALLRAVGQGKLRLARLLLEGGAYVNEGDAQGETALMA
                     ACRARYDDPQNKARMVRYLLEQGADPNIADRLGRTALMHACAGGGGAAVASLLLAHGA
                     DPSVRDHAGASALVHALDRGDRETLATLLDACKAKGTEVIIITTDTSPSGTKKTRQYL
                     NSPPSPGVEDPAPASPSPGFCTSPSEIQLQTAGGGGRGMLSPRAQEEEEKRDVFEFPL
                     PKPPDDPSPSEPLPKPPRHPPKPLKRLNSEPWGLVAPPQPVPPTEGRPGIERLTAEFN
                     GLTLTGRPRLSRRHSTEGPEDPPPWAEKVTSGGPLSRRNTAPEAQESGPPSGLRQKLS
                     RMEPVELDTPGHLCPDSPESSRLSLERRRYSASPLTLPPAGSAPSPRQSQESLPGAVS
                     PLSGRRRSPGLLERRGSGTLLLDHISQTRPGFLPPLNVSPHPPIPDIRPQPGGRAPSL
                     PAPPYAGAPGSPRTKRKLVRRHSMQTEQIRLLGGFQSLGGPGEPGR"
     regulatory      3059..3064
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANKRD34A"
                     /gene_synonym="ANKRD34"
                     /note="hexamer: AATAAA"
     polyA_site      3086
                     /gene="ANKRD34A"
                     /gene_synonym="ANKRD34"
     regulatory      3588..3593
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANKRD34A"
                     /gene_synonym="ANKRD34"
                     /note="hexamer: AATAAA"
     polyA_site      3607
                     /gene="ANKRD34A"
                     /gene_synonym="ANKRD34"
                     /note="major polyA site"
ORIGIN      
        1 acgcccggaa ccgaagcttg cgaagcgggt cgcagagaga gatgggcgtt gcagaatcag
       61 ctggggtcac ttatttccgg tctcactcca gatgaaggag ccactagccg gcgagagttc
      121 accgagggaa cgtgacactc atatctcatc gagggaccgt gttgagggag cccctacaga
      181 gaggccaaag gaggagaggg cctacggaga aatgaacctc tgtaaaagct gctctttagg
      241 gatcagtctt tttgtgactc tagcttcata gcttggtctc tccattactc cagccttcct
      301 ttcaatcata cactgcctct ctccagcacc accaatggat acttcttttc taaaaatgtt
      361 tttctgtggg ttgctgccgt gtctgtgaga agctggacac aaactcattc ctaaaatatg
      421 tggatggaag ctatggtaac catggagaca gggcaggtgg caaggagagg cagagacagt
      481 gtgagagacc aatagacaga taggaagaga gaagatataa ggaatgtttc agacagagat
      541 cgtcaagcaa gatggaaaaa ataagacgtc taagcaagac tgagattaaa gagatgcaat
      601 gtgagagagt gtattacaag tgtgccatgt gccgtgtatg gcaggtcagg tctggcgcac
      661 aggagcgcac aaacacacca agtgcggaga atggggatct gctgaatctc agcgaagaat
      721 ctggatgatg gtccctgtct gggtcgcgga ggagtcccct aaggaacact taggtttgtt
      781 ggggctgagg ggaggtcggc tgagaaaagg aagtcaggat tggagcctct aggtttttga
      841 gggtttatgt gtgcatgagt gggggagcag tttggtgcct gacgccccca cccgcagtga
      901 ctaggctata aatagcacag cagagctccg cccccccccc cccccccccc cccgccaagc
      961 ttctctcctc ccgagccggc gctgtgcccg gggcgctccg ggaggaggga ccaggatccg
     1021 gcgccggggc gcagatactg acaccaaggg aatccgggtg cccccccccc cacgccatgc
     1081 gggcccccag gaaactggct ccgccacctc ggctgccccg tggccacggc cccaatcctg
     1141 gccaggcgga gattctgcgg acattcaggg atcggcttcg tcactgagac ctcaggcctc
     1201 tgccagccac tccccctccc cataccccta gtcatcctcg gcaggtctca gtcccggctc
     1261 catctgtgcc ctcgccccag ccgcagctat gttgcacacc gagggccacg ctcttcttcg
     1321 ggcggtgggt cagggtaagc tacgcttggc ccgtttgctt ctggagggag gcgcctacgt
     1381 gaatgagggt gatgcgcagg gggagactgc gctaatggca gcctgtcggg cccgctacga
     1441 cgacccccag aacaaggcac gcatggtacg ctacctcctg gagcaaggcg cggaccccaa
     1501 tatcgcagac cgattagggc gcacggcgct catgcacgct tgcgccgggg gtgggggcgc
     1561 cgcggtggcc tcgctgctcc ttgcccacgg cgcagacccc tcagtccgag atcacgcggg
     1621 cgcctcggct cttgtccacg ccctggaccg cggggaccgc gagacccttg ccacactgct
     1681 ggacgcctgc aaggccaagg gtacggaggt catcatcatc accaccgata cctcgccctc
     1741 aggcaccaag aagacccggc agtatctcaa ttctccacca tccccagggg tggaggaccc
     1801 tgctcccgcc tctcctagcc cggggttctg cacgtcgcct tcggaaatcc aactgcagac
     1861 cgctggagga ggagggcgtg ggatgttatc ccctcgcgcc caggaagaag aggagaagcg
     1921 ggacgtattt gaattccctc ttcctaagcc ccccgatgac ccatcccctt ccgagccgct
     1981 ccccaaacca ccacgccatc ccccaaaacc actcaaaagg ctcaactccg agccctgggg
     2041 cctagtggcc cctcctcaac cagtcccacc cactgaaggg agaccgggga tcgagcgctt
     2101 gactgccgaa ttcaatggcc tgaccctgac cggtcgaccc cgtctttccc gacgtcacag
     2161 caccgaaggc cctgaggacc cgcccccatg ggcggagaaa gtgactagcg ggggtcctct
     2221 ctctcgccga aacacagcac cagaagctca ggagtctggt cccccttcag ggctgaggca
     2281 gaaactgagc cgcatggagc cagtggagct ggacacccct ggacaccttt gccctgactc
     2341 gcctgagtcc agccgcctgt ccctggagcg ccgccgatac agcgcctccc cgttgaccct
     2401 ccctccagcc ggctcggctc cctctccgcg ccagtcccag gagagtctgc caggggcagt
     2461 atctccgcta agcggaagga ggcggagtcc ggggctgctg gagcggaggg gctcggggac
     2521 gttgctcctg gaccacatct cgcaaacgcg gccgggtttc ctaccccctc tcaacgtcag
     2581 tccccaccct cccatccctg acattcgccc acaacccgga ggtcgggcgc cttcgttgcc
     2641 tgcccctcct tatgccgggg cgccaggctc tcccaggacc aagcgcaaat tggtgagacg
     2701 ccactccatg cagactgagc agatccgcct gctggggggc ttccagagtc taggtgggcc
     2761 tggggagcca gggcgctgag aggagtgaga ggagccaagg agggtgggga ttaggacctt
     2821 aatgggatag gtgggagaac cagctcacac acacaccacg aacaaaggga tctcttgcat
     2881 gtgctcatgg gtgcacagtg cacccacaca tggttaaaca tgtgtccata agcacagtac
     2941 tcttattagc aagaaagaat aagtactcta tttactgggt atatacacac atgtattcat
     3001 gccctggtca tttcacatgc atatgggatt acttgtgtac ctacaggcac agcatatcaa
     3061 taaacacaca gggctagggt cccaaactct cttgcatttg ttcagaagca gtagggaacc
     3121 cttacttatg ggcagtctcc gatgtctttg ccctcctgca gaagcaatcc cttgctttcc
     3181 atgtatgccc tgaaacacag cctatcatga ttttgcacac tctctccgtg gacatcccag
     3241 cccattctgc aggtcttgct tctttctcca ggcctggctc cttattcaca ccctgcttct
     3301 aaccccaacc acttttcagg atatcttttt cactcttctt gggggttcct gcagcaaccc
     3361 ccagcctcag ttctgctgct gtctttactg ctctcaactt cacttctcaa cttcctgctt
     3421 tttattccca ccctgttcct ccaacaacta caacagattg tctcattttc ccagggggtg
     3481 ggtcatgggc tctaagctgc tcttctgtct gtctgagctt atgaacaccc ccacaggtag
     3541 aagtggggag aaaccctaaa tcactcctct ctccacttga catatcaaat aaatgtgttc
     3601 agaagtc
//
