LOCUS       NM_001164440            9586 bp    mRNA    linear   PRI 11-SEP-2024
DEFINITION  Homo sapiens ankyrin repeat domain 33B (ANKRD33B), mRNA.
ACCESSION   NM_001164440 XM_001130634
VERSION     NM_001164440.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9586)
  AUTHORS   Schmutz,J., Martin,J., Terry,A., Couronne,O., Grimwood,J.,
            Lowry,S., Gordon,L.A., Scott,D., Xie,G., Huang,W., Hellsten,U.,
            Tran-Gyamfi,M., She,X., Prabhakar,S., Aerts,A., Altherr,M.,
            Bajorek,E., Black,S., Branscomb,E., Caoile,C., Challacombe,J.F.,
            Chan,Y.M., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Glavina,T., Gomez,M., Gonzales,E., Goodstein,D.,
            Grigoriev,I., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Israni,S.,
            Jett,J., Kadner,K., Kimball,H., Kobayashi,A., Lopez,F., Lou,Y.,
            Martinez,D., Medina,C., Morgan,J., Nandkeshwar,R., Noonan,J.P.,
            Pitluck,S., Pollard,M., Predki,P., Priest,J., Ramirez,L.,
            Retterer,J., Rodriguez,A., Rogers,S., Salamov,A., Salazar,A.,
            Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N., Wheeler,J.,
            Wu,K., Yang,J., Dickson,M., Cheng,J.F., Eichler,E.E., Olsen,A.,
            Pennacchio,L.A., Rokhsar,D.S., Richardson,P., Lucas,S.M.,
            Myers,R.M. and Rubin,E.M.
  TITLE     The DNA sequence and comparative analysis of human chromosome 5
  JOURNAL   Nature 431 (7006), 268-274 (2004)
   PUBMED   15372022
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC112200.3 and AC106760.2.
            
            On Nov 23, 2018 this sequence version replaced NM_001164440.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DRR138528.869427.1,
                                           SRR1163655.117012.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000296657.7/ ENSP00000296657.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-764               AC112200.3         28894-29657         c
            765-894             AC106760.2         26741-26870
            895-1035            AC106760.2         46436-46576
            1036-9586           AC106760.2         57674-66224
FEATURES             Location/Qualifiers
     source          1..9586
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5p15.2"
     gene            1..9586
                     /gene="ANKRD33B"
                     /note="ankyrin repeat domain 33B"
                     /db_xref="GeneID:651746"
                     /db_xref="HGNC:HGNC:35240"
     exon            1..764
                     /gene="ANKRD33B"
                     /inference="alignment:Splign:2.1.0"
     CDS             399..1883
                     /gene="ANKRD33B"
                     /note="Ankyrin repeat domain-containing protein LOC651746"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein 33B"
                     /protein_id="NP_001157912.1"
                     /db_xref="CCDS:CCDS47191.1"
                     /db_xref="GeneID:651746"
                     /db_xref="HGNC:HGNC:35240"
                     /translation="MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFS
                     SLPDTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLR
                     TLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALI
                     TAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHA
                     RDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGS
                     KNCLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPS
                     VGKRRLAVQEILAARAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALG
                     SRGPAAPAPRKASLLPLQRLRRRSVRPGVVVPRVRVSKAPAPTFQPERPARKGSTKDS
                     GHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRTAPWKKRT"
     exon            765..894
                     /gene="ANKRD33B"
                     /inference="alignment:Splign:2.1.0"
     exon            895..1035
                     /gene="ANKRD33B"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..9586
                     /gene="ANKRD33B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9561..9566
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANKRD33B"
                     /note="hexamer: AATAAA"
     polyA_site      9586
                     /gene="ANKRD33B"
                     /note="major polyA site"
ORIGIN      
        1 agtgattgct tctgcttctc ccgcgccagc tgtccccagc tctggggcaa cgctgccagg
       61 tgcccagtcc ccgcgctcga gagagcgcct gcctggctct gaactctggc caggaagggg
      121 cgcgagggga aggccccggg ggaaggcgtg tccccgcgcc ccgccccgcc ccgcctcgga
      181 aagcccccgc ggtcccgccc accccagggg ctcgctcagc ctccggagac ttttttcttt
      241 gagcgcagcc gcctggtgcc ggtttccgcc gagctggagc gcgcgggcca cggcttctct
      301 ggggacgcag aagcgagaag cggggacctc ggcgcgcgcc ccgcgtcccg ctcttcctgc
      361 ccgcgccccg gcccccggcc cgcgccccgg ccgccggcat ggtgctgctg gccgggaccg
      421 ggccggaggg cggcggggcg cgctgcatga ccccaccacc gccgtcccca ccccggggcg
      481 cgcaggtcga ggaggacccc gctgactacg aagagtttga ggacttctcg agtctgccag
      541 acacccgcag catcgcctcg gacgactctt tctacccttt cgaggacgag gaggagcacg
      601 gcgtcgagag cgcggagagc gtcccggagg gcgtcccgga aagcgtcccg gagacggcga
      661 ccctcctgcg cgccgcctgc gccaacaacg tggggctgct gcggacgctg gtgcggcgcg
      721 gggtgagcgt cgaggaggcg caggagactg accgcaacgg caggaccggc cttattgtcg
      781 cctgctacca cggctttgtg gataccgtgg tggccttagc agagtgcccc cacgttgacg
      841 tcaactggca ggacagcgag gggaacacag ccctaatcac agctgcacag gcagggcacg
      901 ctatcatcac taactacttg ttgaactatt tccctggtct tgaccttgaa aggaggaacg
      961 cgttcgggtt caccgccctg atgaaagccg ccatgcaggg tcgaacggac tgcatccgag
     1021 ccctgatgct agcaggggcg gatgtccacg cgagggaccc ccgccgtggg atgtcgccgc
     1081 aggagtgggc cacttacacg ggccgcgtgg atgccgtccg tctcatgcag aggctgctgg
     1141 agcgcccctg cccggagcag ttctgggaga agtaccggcc cgagctgccg ccgccccctg
     1201 aagcggcgcg gaagcccgcg ggctccaaga actgcctgca gaggctcaca gactgcgtgc
     1261 tgtccgtgct gacgccgcgc tccgtgcggg gcccggagga cgggggcgtc ctggaccaca
     1321 tggtccggat gaccacgagc ctctacagcc ccgccgtggc catcgtgtgc cagaccgtgt
     1381 gccctgagag ccctccgagc gtggggaaga ggcggctggc ggtgcaggag atcctggcgg
     1441 cgcgggctgc acggggcccc caggcgcagg aggaggatga ggtggggggc gcggggcagc
     1501 gcgggcggac cggacaggag gacgcggact cccgggaggg ctccccgaga gccggcctcc
     1561 ctcccgccct ggggtcccgg ggccccgcag cgcccgcccc gcggaaggcc agcctcctgc
     1621 ccctgcagcg cctgcggcgg agaagcgtgc ggcccggtgt ggtggtgccc cgggtccgag
     1681 tcagcaaggc gcccgcgccc accttccagc ccgagcggcc ggcgcggaag ggcagcacca
     1741 aggacagcgg ccacctgcag atccccaagt ggcggtacaa ggaggccaag gaggagaaga
     1801 ggaaggcaga ggaggccgaa aagaagcgcc aggccgaggc gcagaaggag aggcgcactg
     1861 cgccctggaa gaagaggacg tgagggcccg tgtgcctggc gctggggccg gggctggggc
     1921 cggggcgggg ccgcagggct gggcgcggag aaggaggcgg ccccgttgcg catcgcacca
     1981 cttccgctcc atggaccacg gggctgcgcg catttccagg ctgtttgtcc aggctgcttc
     2041 caagagaggg ctgagggagc cacatggatt cgcttgtcgc cagccctcct agcaatcagt
     2101 acacctagcg ggcacgttgc ctaaaaggct ccctttagag aacctcaatt aagatttttt
     2161 ttaaagatca atttatcaaa gggcgttttc tccgtaattt tgtattttta atcattattt
     2221 atcaaatttg caacgtttta caagtgatag ggccccttat atccaaggca gttttaatac
     2281 acttgcctga agaccttttg tttaagatac tgtttctagc aataagtatc catgatacct
     2341 gtatgagttc acacagacat catgggattc tccccttttt ggctgtttgg tcttttctcc
     2401 tcatcgtggg tgtaggtgca cactggatgt tcttagtcat tagattaagt gttgccggat
     2461 atttctattt gacggaggca ttggctcgtt gagccacatg atcaagtgag acagaggatc
     2521 agatgttact gtatcttttt aaaactctta tccatatagt aatatattga ggaaaaacat
     2581 attgtcaaat tataaaacaa tggagcgata aacatgtatt tattgctaga attaaactca
     2641 ttttaagcaa ggggttttag gtaaactgga tacgaaatct ttaacattaa aaatagatat
     2701 gagaaaaaaa ctgtcattcg ataaaatgag gcaaatttaa taataaatga ttaccagaaa
     2761 tacaaaatta agccatatgt gctcttaagt aattcgaatc cagatatcct taaaatgtca
     2821 aaaagatgca acaagagtca ggagcccaga atgacgcaaa ttacaggaat ggggaggagg
     2881 tgatttttag aagaggtgag agaatggaat ggggaacaga cttgttttcg gcaaattctc
     2941 ctggagtaga ctgggcagcc ccctcctcca ggctcagttc caaagagtcc gttgtgtgga
     3001 tatttctttt atttttcctt tgaggactgc gcttggtgtt tagttcatcc ttatgccgac
     3061 ctcttagaat ttccaagatg cagggccttg ggcagggcag ggcatgggtg tgatttgcct
     3121 tgggccacaa gctcttggtg agagtcttat gtccacactt ttatctccaa agtgacatgg
     3181 agatcacttt tctcagtgat caaatttgaa tttatcaaag ggggttttct gcataatttt
     3241 gtatttgtaa tcattatcag atttgcagca ttctaattcg gcagggcagg gtatgaaagc
     3301 tggaaactca ggctggagtt tctagttcta atggctctct ggccatgtgg gttgtagagt
     3361 gtctgtcaca tatgcacttt atttcagtat taattgaaat acttggacac gcacgatcac
     3421 aggcctattt ggaggctctg tactatgacc ctaataaccc tagatacatc atgatacatg
     3481 gtgtctgtct caggatgcag gcagggctgg tgcaggcttc tccatactcc cttccacttg
     3541 gcaccagcag gcatcgagca accagggatc ttaaactggc ctctccaaat actccattga
     3601 acaggactgc aggctgcacc caggctaatg ggagattggt gtgttgatga tacagtgttt
     3661 aagatgagat tgcagtgagt tcctccttaa tcccagaagg gcaccatgat gaatgccaca
     3721 ggagactgga ccctctttga gaactgcaga tattagttga ctgtgggtca ccctcgtggc
     3781 caaggagttg ggattggcca tgtcttcttc gaggaggtgg agactgtaac tgacactggt
     3841 tatctttggg gttgtctttc ctgaatcctt tggcatgtgg caccttcctg ccacatgtag
     3901 ataattcacg gcattaccaa gtcaccacga gccccaccct cacctctgtc aaccgaggac
     3961 ccagccaggc agtgccatgt ggtctcccag gcacgcttct caacaccggc tacccctgct
     4021 gtgaaggttc tcaaggccct ggtccgggga gccaagccct gggagcgccc taaagctccg
     4081 caggtaactg cactgcagcc cgcattgaga accgcagctc taacacagtg attgcgagag
     4141 gacacccatt ctgagctccc acagagggct ccacctcccc aagaatgtct cattgtcatt
     4201 ggaacagcca gggtcaggca gcttctgctc ggactgacgt ggcgtctgac ccttggtggg
     4261 ttgccagaca ttcctgcctg tttccaccat gggaagctgt cactgggaat ggtatggagc
     4321 cctcacttct accccaagcc tgggtgtctg ctgcctccat gtcaaaaatg gacatttctg
     4381 gtcctgccca gctgctacct caccacaacc catgctcaga gttgtcaggg atgcgtggaa
     4441 cagcaatgat gggacagcaa atgactggca atttccccag gtcccacgct gttctggagt
     4501 ggacgtgttg cggccctgcc cccgatgtgt tccagcctca tccaggtgca caggatactc
     4561 tggggccagc acagggattg tccagtgatg ctcctggtgt ccacaaaaca gctctagaga
     4621 tacctgcatt ttgaaaagcc tgctgagcca acaagcttgg ggcaggacac ggatttcttt
     4681 ggcaaatctg caggcgagct gaccacttgc ctggtgagtg gaagctgcca ttacctggcc
     4741 agtgtttgca actcgaggga aaatgacagc tgcatggggg gaagcctgac ctcccgggga
     4801 gctttattgt ggcctcagtg gaaagattgg attttgaaac ctgccagacc caactgaaag
     4861 aagggtcatt cctgattgag ttggagactc tccccagtcc ctctctctgg actcattcta
     4921 gctgtggcct gcctgtggac agcccttccc tttggcccat gcggcgggtc caggcagctc
     4981 ctgcagctgt gctcatggct gctggcccag aacttctcat ttttgccatg tggaagcaga
     5041 tttgctagta gaggaatttt ccaagtcaag ggaagtgttg ccaaacctct tgcctcgacc
     5101 tgtggggggc cttctgctct tgttttctca ttctctttgg agtgggcaca gaggggacaa
     5161 gtcggccccc agtgaggctc agggagtgca ggagaccagg gagggaagcc cagatgatgg
     5221 ggaaacagag ccaccttgag ggggtgtcat ggggtcagtg tcagggtgat ctgacgggtc
     5281 agttcatact taagcaacat tattctgttc gtttcttttg ggtaaggaat tcctcatggg
     5341 aggtgtggtc atctggtcgt agaggtggac agaaacaccc cctcgtcttc ctgagccatt
     5401 tggaagccct ttcctctagc cctaggtact ggtgacacag gcccctcggt ctcaggatgt
     5461 ggacagggct gggaggtgca ggcttcttgt cccatcccca ctcagtatca tcgggtatct
     5521 ggtagtcagg ggtctcacag tggcctctcc aaaagcctgg tgtccttgga gaacattttt
     5581 cattttgtct gttttcgttg ctttgaacag ctgcattcac tcaccgaggg ctcgccctcc
     5641 ctggatctgc catgtggttc agggaggagg ggaccgatga gcaccgaccc cttctcttca
     5701 cctgtcagtg gccaccacag tgccccctct ggctttgcca ccacgttctc ctgcccccgt
     5761 caccttgtct cttctaactc attagccttt ccttcctttg tctgttttct tctcccagct
     5821 ggtttaagtt cttgatcatc cctggcacca cctaccctaa ggtcttccaa gaacagaaaa
     5881 gccagggcct gtgtggggca atgtgttgtc cctgtcgggt tatggtggga cctcctagac
     5941 cccagagtga atgaatggca ggcctgccag tgactgtgct gatggcttag aattcctaca
     6001 cggctgtgcc tctcccaccc cgtcctcttt gctcggaagg gagacctggt ttgctctcct
     6061 ccatgacagc ccagcccctg ctgtgcacag gggtggggct cgggatccct ccctgcaccc
     6121 tgatgtttat taactgtaga tagtgaattt caagttgaca ggtaccttct cagggattta
     6181 tatataaata tagttagagg aaaagttgaa gtctatttta ctacttttta gtgtttgagt
     6241 aaattatgct ttaactggac agaagaaata tttctcagac aatgtcgatg ctgctgatga
     6301 caactgagat gcctggagct cacccttgat ggagacttcc ttggtgattg gagatggggg
     6361 actctggtgg cagaaatggc tttggggtag gtgtgaagtt gcttcagtcc ctctgagttg
     6421 cctcttctgg atggaacgtg tgtatcaaca acaatgaaat gcacctccgt gtgcatggag
     6481 gcggctgatg agaatacaga taggccagtc ctcgctcttc cctccagaac cggccgctcc
     6541 cggtctgacg ttggagcacg tgaactaaga gtgacaattt tttctacttg cttctgtgaa
     6601 taaagtgttc tacagtcagc ccagcactaa actcaccaga aaagaggagg gaacagcacg
     6661 gagccattca tctggaatta ctcgatgtgc agaggctgcc ccttggccgc acttgggaac
     6721 atcgtggaca tcttccttcc tctcaggctc ctcctgacag actcctggca gcactggaga
     6781 cctcaggact atggagatca gaattgtaat ggctttgtca tctcagtgtg gccactcctg
     6841 aggcaagagg ctcctcctgg gagcaggaga gagagagttt gtgatgttgg ttggaaaata
     6901 ggatttatgg atgcaggagg gccgtgctag gcccctctgc ccgcttctct ccctgctgtt
     6961 ggcggtgacc aggtctcagg agcggagacg aggctgttgt gagtgaaaca gaagcccctg
     7021 gcatagggcc agaccctagg cctgaaaagg atgcaaagcc tgctgttttc aggctgttgg
     7081 gaagaatcgt gcgtaccgag tgattatgat gaaacgtatc ccagagagga aatgaatggg
     7141 acctgaaaag tgggtctgcc acatccctgg tagcccgcct ccaagagcac tacactcccc
     7201 ccagccccac cggccacact acatgacgtg ggaaggctgt ccgttcatcc ttaccctggg
     7261 gactcaagtg tgctctgcgg agtgagtcac agccctgatg tgcaccctgc actactcttt
     7321 ccccaggtgc gccggagacg caggcttgct catttccgtc ctgacacagc tcgctgttcc
     7381 tgcggtggtc agagtccccc tgtgctgtgt cagctcctgg acactactag tctttcacat
     7441 gataaagcgc gagcactttt tcgcttttgc agtatttggg gaaattctaa cacatttccc
     7501 ggggatttgc ccaggtccct ccacctccca cggtgggtaa ctgtgtggat tctgcacctg
     7561 gcaatcggcg ctcccctttg gaaacacctg ggggccctgt ttcttccagc ctggtccttg
     7621 gtttctaccc cagccgcttt cagccggcac ctgcatggga ctgcctggag ggccacggtc
     7681 cagggaagga caggtgggac cctgaccatg acagatcttt ctaaaacaat aaagtcccat
     7741 tgatgacaac tgcagtggga tgaatgccat tgcagcggtc atgctgggag ctgccgagag
     7801 cttacaacaa aagcagttcc tctcaagaca ctgcttgcat cttccctcca cgcctctcgg
     7861 tgcatttgga acttgtttat gcgctggtat aactcgagtc agctgcttat ttctgtgccc
     7921 ttgcactcac aggttccttc attaacattt taaataagtg gctaaaaaaa ctcctctgga
     7981 ggttgttttt gaaagagaca ggaaaaagaa acacacagta cctggattgt tttgacttat
     8041 tttcaagcga ctcagctgaa agccggtgtt gcatacacaa tttcctcacg ctgacccagc
     8101 ctgactaaga cttgataaaa ggcacagccc ttggcagcag gcagtgccaa tgtggacagt
     8161 gtacactaag ctgtgagtgt gtgcacgggc gagcacatgt atgtgtactc atacatccag
     8221 atgaactaaa gggacactgg gctttgtgct ggcaaaggtt acgatgctgc tgtagcttgg
     8281 ctgtgggccc caggcagtgt cagatggaac ctgctttgat ggcgtgttgt tcagtgtact
     8341 cagtggggtc tcacatggcc cgaggaccca ctgtgagcac tccgcccgct gtggcacaga
     8401 acacggctgg ggtcatcaca gcccaggtct ttattgaaag gcggctcata tagaacccat
     8461 ttggccaggt ctgggccatc tctctgcctc tgccctatct tggctgcctg gaggggccca
     8521 ggcccaagag gattctttac ccctggaaga gctccccagg cattcagcct atggcccttg
     8581 acatttggct gcaggttacc gtcagaatca acaccatatc ctgaggaagc cctggtattt
     8641 ccccaagtct gcctatgtat tagacactct aatcaatgct aacacagttc agtttttgag
     8701 ggaactagtt ttgtcataat actacacccc tctattgttt ttaaataaga aaaaaaaaaa
     8761 ccccacgaaa ctttccatca aagcaatggt ccgtgttggc ctgatgcttt aagaagtttg
     8821 aggaggtagg tatggaggca ccttaacacc agtttttgag cagaagttct agaagctgat
     8881 ttagaactac acagctatgg atacacctga tgaaaaccgc aaaaggcgat gacaggccca
     8941 gaaatatgac cagcaagccc gtgagccttt ggggcatccg actgaatttg aaaataatac
     9001 cccattcaga tgaacattaa aagccaatgt actggaattc tctttgttct gcccgacatt
     9061 tgggggtgtc caaggacctg tgtttttaac aaagatgact ttatgaccgt tctaaggatt
     9121 gaacagattc ctgcacaggg tgccaggttt caagttaggt cctcttagta taagctctct
     9181 ttttttctga atgtaaacct atttgcattg tcatttctaa taatccagta ggtttctgga
     9241 tattgtaaag atactgagta cagatataac tgtgtaaatt tcatagtgtt ttattttgag
     9301 gtgagagttt tgttatagtt tataaaagat attttcctat tcagacctca gggctatttt
     9361 gggacctaca aataaatgtg attcccagca gcttcaattt ttgatattca aaaagttaat
     9421 aatctttaag ctaaatataa tgtgatatga ttcagaaaaa aatgtttttc ccttttaact
     9481 tctaacaaat tatgtatcta atgtttaaaa aatatggaaa aaagggataa tgtaaaaatg
     9541 tgggagaatt gtggctaaag aataaaaaat cacttgttaa aacgca
//
