LOCUS       NM_030816               5658 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens ankyrin repeat domain 13C (ANKRD13C), mRNA.
ACCESSION   NM_030816
VERSION     NM_030816.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5658)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 5658)
  AUTHORS   Parent,A., Roy,S.J., Iorio-Morin,C., Lepine,M.C., Labrecque,P.,
            Gallant,M.A., Slipetz,D. and Parent,J.L.
  TITLE     ANKRD13C acts as a molecular chaperone for G protein-coupled
            receptors
  JOURNAL   J Biol Chem 285 (52), 40838-40851 (2010)
   PUBMED   20959461
  REMARK    GeneRIF: ANKRD13C acts as a molecular chaperone for G
            protein-coupled receptors, regulating their biogenesis and exit
            from the ER.
REFERENCE   3  (bases 1 to 5658)
  AUTHORS   Simpson,J.C., Wellenreuther,R., Poustka,A., Pepperkok,R. and
            Wiemann,S.
  TITLE     Systematic subcellular localization of novel proteins identified by
            large-scale cDNA sequencing
  JOURNAL   EMBO Rep 1 (3), 287-292 (2000)
   PUBMED   11256614
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL136717.1, BC028840.1, BU622247.1, CD000035.1, AL353771.8 and
            CK299538.1.
            
            On Nov 23, 2018 this sequence version replaced NM_030816.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            transcript and genomic sequence to make the sequence consistent
            with the reference genome assembly. The genomic coordinates used
            for the transcript record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803613.234525.1,
                                           SRR1803614.13734.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000370944.9/ ENSP00000359982.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5                 AL136717.1         13-17
            6-1550              BC028840.1         7-1551
            1551-1975           BU622247.1         16-440              c
            1976-2700           BC028840.1         1977-2701
            2701-3325           CD000035.1         23-647
            3326-5219           AL353771.8         117795-119688       c
            5220-5655           CK299538.1         16-451              c
            5656-5658           AL353771.8         117356-117358       c
FEATURES             Location/Qualifiers
     source          1..5658
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p31.1"
     gene            1..5658
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /note="ankyrin repeat domain 13C"
                     /db_xref="GeneID:81573"
                     /db_xref="HGNC:HGNC:25374"
                     /db_xref="MIM:615125"
     exon            1..744
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /inference="alignment:Splign:2.1.0"
     CDS             315..1940
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein 13C"
                     /protein_id="NP_110443.3"
                     /db_xref="CCDS:CCDS648.2"
                     /db_xref="GeneID:81573"
                     /db_xref="HGNC:HGNC:25374"
                     /db_xref="MIM:615125"
                     /translation="MTGEKIRSLRRDHKPSKEEGDLLEPGDEEAAAALGGTFTRSRIG
                     KGGKACHKIFSNHHHRLQLKAAPASSNPPGAPALPLHNSSVTANSQSPALLAGTNPVA
                     VVADGGSCPAHYPVHECVFKGDVRRLSSLIRTHNIGQKDNHGNTPLHLAVMLGNKECA
                     HLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKA
                     LKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGD
                     LSFIFNGDAAPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDIYSATLSTKS
                     ISFTRAQTGWLFREDKTERVGNFLADFYLVNGLVLESRKRREHLSEEDILRNKAIMES
                     LSKGGNIMEQNFEPIRRQSLTPPPQNTITWEEYISAENGKAPHLGRELVCKESKKTFK
                     ATIAMSQEFPLGIELLLNVLEVVAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITA
                     TVTFQEFRYDEFDGSIFTIPDDYKEDPSRFPDL"
     exon            745..786
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /inference="alignment:Splign:2.1.0"
     exon            787..891
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /inference="alignment:Splign:2.1.0"
     exon            892..977
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /inference="alignment:Splign:2.1.0"
     exon            978..1023
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1090
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1235
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1367
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1368..1529
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1530..1609
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1610..1708
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1709..1809
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1810..5658
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4038..4043
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /note="hexamer: AATAAA"
     polyA_site      4069
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /note="major polyA site"
     regulatory      5634..5639
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
                     /note="hexamer: AATAAA"
     polyA_site      5658
                     /gene="ANKRD13C"
                     /gene_synonym="dJ677H15.3"
ORIGIN      
        1 gagcaagagg aagatggccg tgccctgttt ttcggtgtaa ggcagcgacg gcggctgcga
       61 cggcgagact gagatcctgg tgtcgtgggc acctgagttc tagcttcccc cagcgagcgc
      121 gcgtcccttc gtgcctaggc gagagccggc tcttccccgg gagatgcgtt tgtcccaggc
      181 tcgggggctc agtgggagtt catgctgcgc tggaggctct tggccaccgc tctaatcgcc
      241 ttgtgccgcc gcagcgccag ctccgtcgcc agcggtgagc ctcccgattc ccccccttgc
      301 ccctggcggc ggcgatgacc ggggagaaga tccgctcact gcggagggac cacaagccca
      361 gcaaagaaga aggggacctg ctggagcccg gggatgagga agcggcggct gccctcggcg
      421 gtacctttac cagaagcagg attggcaagg gcggcaaagc ttgtcataag atcttcagta
      481 accatcacca ccggctacag ctgaaggcag ctccggcctc ctccaatccc cccggcgccc
      541 cggctctgcc gctgcacaat tcctccgtga ctgccaactc ccagtccccg gcccttctgg
      601 ccggcaccaa ccccgttgct gtcgtcgcgg atggaggcag ttgccccgca cactacccgg
      661 tgcacgagtg cgtcttcaag ggggatgtga ggagactctc ctctctcatc cgcacgcaca
      721 atatcgggca gaaagataat cacggaaata ctcctttaca ccttgctgtg atgttaggaa
      781 ataaagaatg tgcccattta cttttggctc acaatgctcc agtcaaggtg aaaaatgctc
      841 agggatggag ccctctggcg gaagccatca gctatggaga taggcagatg attacagctc
      901 ttttgaggaa gcttaagcag caatccaggg aaagtgttga agaaaaacga cctcgattat
      961 taaaagccct gaaagagcta ggtgactttt atctagaact tcactgggat tttcaaagct
     1021 gggtgccttt actttcccga attctgcctt ccgatgcatg taaaatatac aaacaaggta
     1081 tcaatatcag gcttgacaca actctcatag actttactga catgaagtgc caacgagggg
     1141 atctaagctt cattttcaat ggggatgcgg cgccctctga atcttttgta gtattagaca
     1201 atgaacaaaa agtttatcag cgaatacatc atgaggaatc agagatggaa acagaagaag
     1261 aggtggatat tttaatgagc agtgatattt actctgcaac tttatcaaca aaatcaattt
     1321 ctttcacgcg tgcccagaca ggatggcttt ttcgggaaga taaaacagaa agagtaggaa
     1381 actttttggc agacttttac ctggtgaatg gacttgtttt agaatcaagg aaaagaagag
     1441 aacatctcag tgaagaggat attcttcgaa ataaggccat catggagagt ttgagtaaag
     1501 gtggaaacat aatggaacag aattttgagc cgattcgaag acagtctctt acacctcctc
     1561 ctcagaacac tattacatgg gaagaatata tatctgctga aaatggaaaa gctcctcatc
     1621 tgggtagaga attggtgtgc aaagagagta agaaaacgtt taaagctacg atagccatga
     1681 gccaggaatt tcccttaggg atagagttat tattgaatgt tttagaagta gtagctccct
     1741 tcaagcactt taacaagctt agagaatttg ttcagatgaa gcttcctcca ggctttcctg
     1801 taaaattaga tatacctgtg tttcccacaa tcacagccac tgtgactttt caggagtttc
     1861 gatacgatga atttgatggc tccatcttta ctatacctga tgactacaag gaagacccaa
     1921 gccgttttcc tgatctttaa ctgacgtgga aaaggatgcc gtctaaccaa ggaaagaaaa
     1981 tacagagacc ctagaagtgg atccaaatag aagggacaaa tgctttcagt gaagaaaagg
     2041 gaattacaca ttgaatcgac acatcagtaa tacgatacag tgaaatgggc ctctaataag
     2101 aatttcagcg agttttctga tgtgccattt tttgtctttt taaaaatata catattataa
     2161 atgtaatagt ttgacacatt aatgacccta agacctgcgt atgtgaagca gctatgagtg
     2221 ctgtgatttg tttttaaaaa tttttacact tcttgttgaa atatatatgc atataaatat
     2281 atctatatct atatctatat ctaaaacact cctggaccat taacgtaaat taaatgtctt
     2341 aagagatatg gagccctttt aaacttgtca tctttatgca aggtgacatt tataaatatt
     2401 ccttcgagct ttgttttcat aaaatgtaaa ctatgtaaca ttatgtatag ttcagtaatt
     2461 tgaatgtttg ttcaatataa tgaactagaa ggaatgcaat tttctgtaga tgaatgaacc
     2521 aaatggtaac cattaaacaa ttgcatttat atgttgcaat acatttcaga aggagcgttc
     2581 actctgcagg gaataaggta cctcctttag caccttagtg caattcattg tggtgctatt
     2641 tgtttttacc tgaatgtttg ttactaatct tcctttcata gaacctctat tttttttttt
     2701 tctaaacttg agtttgagtc cttgttatgg tcatcataag gtaatggtta gcatgtttaa
     2761 agatattcct cttccaaatc tcagcacttt aaaaaaaaat ccaaattttt aaacttgctt
     2821 cctaataagt acacatcggt ctgattattt tgtttgtttt tagtagaata tggatgcatt
     2881 ggtgtcagtt ttaaaaaaca atacacatat tttggacaac cctacatatt taatcctttc
     2941 aaaataagat aaaaacattt tatatgctaa cagaatatat ttgttacaag ttaaagtcca
     3001 gaagtataca caagattgat tactcctatt atttttttta aatcacagga aaatattgat
     3061 ttcattgtct ccaaagtgat aaaatcatgt attactcatt tttgcactta aaatttttct
     3121 tatttattcc aaggtggttt gaaggtccaa gtatgaaaat aaattagggg gattaatgta
     3181 taacagttat aaagtatcat gttgtattaa agagcttact tagattgatg tttttaaaat
     3241 gtatcctgat gaatgtctca agaatgcatc tgtcaagttt tttagactga ccagtagctt
     3301 aaactttttt caggatttta ggtaatttga aaggagttta gagaccctta ttgaaaatat
     3361 gatttaaaaa tccaaagcat aaaccgtaag aaaaatttta aataaacatc tttaaagctg
     3421 catcttccat actgatacat gcattgcgta tgttgacatt aaatacattt tataatgaag
     3481 aaaaataatc atagtaaaaa attgaaagac ctaattacta cgttacatgg acctattgaa
     3541 ttttggggga acgtgttagt aaacccagac tagctttgtt gaatagaagt tgatcgctgt
     3601 tatttaggaa atgggtagat caaatgactt agagactgaa ttatcctatc agtggttaca
     3661 tggggttgga gacactgaaa ggcagtgatc actgttgctt ctaggctccc ttactttgta
     3721 ggaatatggt atactttcag gaatatgcta tatatgtttt cataagtaca gacaccttag
     3781 ggaagaaaaa aagtgggtaa ttgaagctta tggttgatta atttcctaac agcacagcta
     3841 tgaatatttt gctggggtac actggaggta ggaagactac tggaaatttt tgcacttgaa
     3901 ttttgttttt aaagcttttt tctttaaaga atggtagaaa cagattatcc attccaaaat
     3961 gtcttttctc tgatcacaaa gagcaaacaa atgtcaatat ctcttatgat ggtgaaaaaa
     4021 aggaattaat cgatgcaaat aaacttttca cagtattact tttaatgaag atttttcgaa
     4081 atgtgccttt taatccagtt aatgaatgaa gctatatgca gtgtttcaaa tgaataagtc
     4141 aaaacaccat atgttttcat aataccacat gaaaaatcaa gattttgcaa tgtaggtaca
     4201 caaaattcta tatgttcttc tccatttgtg attttgaaac tgtttaaatt ggtaggggga
     4261 caatcgtata gtcatcttca atagccattt agaaatggtt aatattcttg cccactggta
     4321 tggtatccag agaagatatg gtttccatct ttgagaaaat aattctctga tgagacaatt
     4381 tgccctctgt agatattcac atacagagaa ttgccaaact tcataaaagg gtagtatgaa
     4441 gtagatgccc tgatttttgt gagtataaga agtacagatg atggtttgga aactgtcaca
     4501 tctgtctgct gatacatgtt agtagatgaa aaactgtttc cttctgctca gaactggaat
     4561 taagccccac tcatgctaat aaaaatgggt ttttatagta gtattcacat acagtttatt
     4621 attcacacac tgggggaggg tgatgaataa tgattattta atgagccctc ttcctagttt
     4681 tccctaagtc tgcagaagac aaagatcctg tttccaggcc atgaaaggac tgaagtaaat
     4741 attgtaaata agtacagctg acccttgaac aacatggagg ttaggggttc agttgaaaat
     4801 ctgcatgtaa gtggacctgt gcagtccaaa cctgtgttta actgctgaat taaaggtgct
     4861 tccttctgct cattgatatt acccatattt acaaacatgc tagagaaaag caactggtgt
     4921 aaaacttgcc cccactagag aaatggacag gaggtattaa gtcacttgta aagatagata
     4981 gcagaactaa gcttggtaaa agcccatgat tgtttgtata ctataaatta gccaaaacta
     5041 ctcttgcaaa gcattttatg tcagaaatct ggggcaatag taactaactc tggttgccac
     5101 ctaaaaattt cataacatgt taagaatcac attttttaca tcatgcaaac catccttaca
     5161 gagtgagctt accttgtgat gagcttttta attgttacag ttcattttag aagagtaata
     5221 ctttcagtca taatggtacc tatggtacat agaattacaa ttttgctttt tccacacact
     5281 gaaaaatatt gaagcaaaat cttaagaact tctaagaaag gtgcttgtta atcattcttg
     5341 gttttcatca tgttttgcgg tgaaaatgac tttaattaga gtagaaatat tgtctaacat
     5401 aaaaccaaaa agataaaacc caccacttat ttacctgtac ctcccataca tagagttctt
     5461 gatgactaaa gaaggatgac agtaattggg atgttctaaa tacagttgtg tgtcacttaa
     5521 tgatgggtac atgttctgtg gaatgcatca ggtgattttg tcattgtgag aaccatattg
     5581 ggtgtactta cacaaaccta ggtggtatag cataccactc acctagacta tacaataaag
     5641 cctattgctc cgagacca
//
