LOCUS       NM_001282771            3405 bp    mRNA    linear   PRI 31-MAY-2024
DEFINITION  Homo sapiens ankyrin repeat and MYND domain containing 1 (ANKMY1),
            transcript variant 3, mRNA.
ACCESSION   NM_001282771 XM_005247018
VERSION     NM_001282771.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3405)
  AUTHORS   Lutterbach,B., Sun,D., Schuetz,J. and Hiebert,S.W.
  TITLE     The MYND motif is required for repression of basal transcription
            from the multidrug resistance 1 promoter by the t(8;21) fusion
            protein
  JOURNAL   Mol Cell Biol 18 (6), 3604-3611 (1998)
   PUBMED   9584201
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK314534.1, AL833866.1 and BC073146.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001282771.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK314534.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000401804.6/ ENSP00000385887.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1501              AK314534.1         18-1518
            1502-3404           AL833866.1         452-2354
            3405-3405           BC073146.1         2449-2449
FEATURES             Location/Qualifiers
     source          1..3405
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q37.3"
     gene            1..3405
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /note="ankyrin repeat and MYND domain containing 1"
                     /db_xref="GeneID:51281"
                     /db_xref="HGNC:HGNC:20987"
                     /db_xref="MIM:620842"
     exon            1..108
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            109..271
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     CDS             126..3218
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /note="isoform 3 is encoded by transcript variant 3;
                     ankyrin repeat and MYND domain-containing protein 1;
                     testis-specific ankyrin-like protein 1; zinc finger MYND
                     domain-containing protein 13"
                     /codon_start=1
                     /product="ankyrin repeat and MYND domain-containing
                     protein 1 isoform 3"
                     /protein_id="NP_001269700.1"
                     /db_xref="CCDS:CCDS63185.1"
                     /db_xref="GeneID:51281"
                     /db_xref="HGNC:HGNC:20987"
                     /db_xref="MIM:620842"
                     /translation="MEGAHASLSLEDEVSGAGSRQRPLEGKGGETPAAEEPGSLKNYA
                     VFATRDVSAAPEKEEEEAEGPLRAQDLRESYIQLVQGVQEWQDGCMYQGEFGLNMKLG
                     YGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYGTMYMKTRLFQ
                     GLYKADQRFGPGVETYPDGSQDVGLWFREQLIKLCTQIPSGFSLLRYPEFSSFITHSP
                     ARISLSEEEKTEWGLQEGQDPFFYDYKRFLLNDNLTLPPEMYVYSTNSDHLPMTSSFR
                     KELDARIFLNEIPPFVEDGEPWFIINETPLLVKIQKQTYKFRNKPAHTSWNMGAILEG
                     KRSGFAPCGPKEQLSMEMILKAEEGNHEWICRILKDNFASADVADAKGYTVLAAAATH
                     CHNDIVNLLLDCGADVNKCSDEGLTALSMCFLLHYPAQSFKPNVAERTIPEPQEPPKF
                     PVVPILSSSFMDTNLESLYYEVNVPSQGSYELRPPPAPLLLPRVSGSHEGGHFQDTGQ
                     CGGSIDHRSSSLKGDSPLVKGSLGHVESGLEDVLGNTDRGSLCSAETKFESNVCVCDF
                     SIELSQAMLERSAQSHSLLKMASPSPCTSSFDKGTMRRMALSMIERRKRWRTIKLLLR
                     RGADPNLCCVPMQVLFLAVKAGDVDGVRLLLEHGARTDICFPPQLSTLTPLHIAAALP
                     GEEGVQIVELLLHAITDVDAKASDEDDTYKPGKLDLLPSSLKLSNEPGPPQAYYSTDT
                     ALPEEGGRTALHMACEREDDNKCARDIVRLLLSHGANPNLLWSGHSPLSLSIASGNEL
                     VVKELLTQGADPNLPLTKGLGSALCVACDLTYEHQRNMDSKLALIDRLISHGADILKP
                     VMLRQGEKEAVGTAVDYGYFRFFQDRRIARCPFHTLMPAERETFLARKRLLEYMGLQL
                     RQAVFAKESQWDPTWLYLCKRAELIPSHRMKKKGPSLPRGLDVKEQGQIPFFKFCYQC
                     GRSIGVRLLPCPRCYGILTCSKYCKTKAWTEFHKKDCGDLVAIVTQLEQVSRRREEFQ
                     "
     exon            272..461
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            462..605
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            606..1078
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1295
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1460
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            1461..1957
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            1958..2129
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            2130..2270
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            2271..2411
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            2412..2519
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            2520..2651
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            2652..2765
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            2766..2931
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            2932..3010
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            3011..3171
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     exon            3172..3405
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3372..3377
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /note="hexamer: AATAAA"
     polyA_site      3405
                     /gene="ANKMY1"
                     /gene_synonym="ZMYND13"
                     /note="major polyA site"
ORIGIN      
        1 gtaggcgcag ggctggcaag cagtcgggac gggagcgcgg gcgtccgcgg tggctgcagt
       61 cccgtcggtc tccctgctgt ccggcgcgag ctcttcgagt cttgcttggt tggaagacca
      121 cagacatgga aggggcccat gcctccctta gcttagagga cgaagtctct ggggctggca
      181 gccgccaacg cccgctagag gggaagggcg gcgagacccc tgctgccgag gagccggggt
      241 ccctgaagaa ctacgctgtc ttcgccacaa gggatgtttc agcagcccct gagaaggaag
      301 aggaggaagc tgagggcccg ctgagggcgc aggacctgag ggagtcctac atccagctcg
      361 tccagggtgt gcaggagtgg caggatggtt gcatgtacca gggggagttt gggttgaaca
      421 tgaagcttgg atatggcaaa ttctcttggc ccacaggcga gtcataccat gggcagtttt
      481 accgggacca ctgccatggc ctgggtacct acatgtggcc agatggctcc agtttcacgg
      541 gcacatttta cctcagccac cgagaaggct acggcaccat gtacatgaag acacggcttt
      601 tccaggggct atacaaagcg gaccagcggt ttgggccagg tgtcgagacc taccccgatg
      661 gcagccagga cgtggggctg tggttccgag agcagctcat caagctgtgc acccagatcc
      721 ccagtggctt ctccctcctc agataccctg agttctccag cttcatcacc cacagccctg
      781 ccaggatcag cctctcagaa gaggagaaaa cggagtgggg actgcaggag ggacaggatc
      841 cctttttcta tgactataag cggtttcttc tgaatgacaa cctaacgctg cctccagaaa
      901 tgtatgtcta ctcgaccaac agtgaccacc tgcccatgac aagctctttc cgcaaagagc
      961 tggacgcccg catcttcctc aatgaaattc ctccgttcgt tgaggatgga gaaccatggt
     1021 tcataatcaa tgagacccct ttgttggtca aaatccagaa gcaaacttac aagttcagga
     1081 acaagccagc tcacaccagc tggaacatgg gcgccatcct ggaggggaag cgcagtggct
     1141 ttgcaccctg tgggcccaaa gagcaacttt ccatggagat gatcctaaag gctgaggaag
     1201 ggaaccacga atggatttgt aggatcctga aggacaactt tgctagtgct gacgtggcgg
     1261 acgcaaaggg ctacactgtg cttgctgcgg ctgctactca ctgccacaac gacattgtca
     1321 accttctcct ggactgtggg gccgacgtga acaagtgctc agatgagggt ctcacggcac
     1381 tcagcatgtg tttcctcctc cactaccccg cccagtcctt caagcccaat gttgctgaac
     1441 ggaccatacc tgagccccag gaacctccaa aattcccagt tgttccaatc ctttcatcat
     1501 catttatgga cacaaacctg gagtctctgt actatgaggt gaacgtgcct tcccagggta
     1561 gctatgagct gaggccaccg ccagcaccac tgctcctgcc acgcgtctca ggcagccacg
     1621 agggcggcca cttccaggac accgggcagt gtggggggtc catagaccac aggagcagct
     1681 ctctgaaggg ggactccccg ttggtgaagg gcagccttgg ccatgtggaa agcgggcttg
     1741 aggacgtgtt gggaaacaca gaccggggca gtctgtgcag tgctgagacg aaatttgagt
     1801 ccaacgtgtg tgtgtgcgac ttctccatcg agctctcgca ggccatgctg gagagaagcg
     1861 cccagtccca cagcttgctg aagatggcct cgccctcacc gtgcaccagc agcttcgaca
     1921 aagggaccat gcggaggatg gcgctgtcca tgatcgagcg gaggaagcgc tggcggacca
     1981 tcaagctgct gctgcgccgg ggcgcggacc ccaacctgtg ctgcgtgccc atgcaggtcc
     2041 tgttccttgc tgtgaaggcc ggggacgtgg atggggtgag gctgctgctg gagcacgggg
     2101 cgaggaccga catctgcttt ccgccgcagc tgagcaccct gacaccactc cacatcgctg
     2161 ccgcccttcc tggggaggag ggggtacaga ttgtggagct gctgttgcat gccatcaccg
     2221 atgtggacgc caaggcatcc gacgaggacg acacttacaa gcccggcaag ctggacctgc
     2281 tgccctcaag tctgaagctc agcaatgagc caggccctcc ccaagcctac tacagcacgg
     2341 acacagccct cccggaggag gggggcagga cggctctgca catggcctgc gagcgggagg
     2401 atgacaacaa gtgtgccagg gacatagtcc ggctccttct atcccacgga gcaaatccta
     2461 acctgctgtg gagtggccac tccccgctct ccctgtccat tgccagtggg aatgagctgg
     2521 ttgtgaagga gctcctgacc cagggagctg accccaacct gcccctgacc aaaggcttgg
     2581 gcagtgccct gtgtgttgcc tgtgacctga cctacgagca ccagaggaac atggacagca
     2641 agctggccct gattgaccga ctcatcagtc acggggccga catcctgaag cctgtaatgc
     2701 tcaggcaggg agaaaaggag gcagtgggca cagccgtgga ctatggctac ttcagattct
     2761 tccaggaccg gaggattgcc cgctgcccct tccacacgct gatgccagca gagcgcgaga
     2821 cgttcctggc gcggaagcgg ctcctggagt acatgggctt gcagctacgg caggctgtct
     2881 ttgccaagga gagccagtgg gaccccacgt ggctgtacct gtgcaagaga gcggagctga
     2941 tccccagcca caggatgaag aagaagggcc ccagcctgcc caggggcctg gatgtgaagg
     3001 agcaggggca aattcccttc ttcaagttct gctaccagtg tggccgctcc atcggggtcc
     3061 gcctcttgcc ctgccctcgc tgctacggga tcctgacctg cagcaagtac tgcaagacca
     3121 aggcctggac cgagttccac aagaaggact gcggggacct ggtggccatc gtgacacaac
     3181 tggagcaagt ttccaggagg agagaagaat tccagtgaag cagcagctgc acgtccgagg
     3241 cttggggagg acccaggact gtgtgggttt cttacctgcc tgagccacct cagggaatct
     3301 tccagcctaa tgcaggcatt tctgcacctt tggggtcatg ctttgtagca gtgtctccct
     3361 tgcgacctcg caataaattg gccccacggg gtgattttga cagtc
//
