LOCUS       NM_001276713            2575 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens ankyrin repeat and death domain containing 1B
            (ANKDD1B), mRNA.
ACCESSION   NM_001276713
VERSION     NM_001276713.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2575)
  AUTHORS   Zhang,T., Wei,H., Li,M., Han,W., Zhang,W., Zhang,X., Zhang,B.,
            Jiang,Z. and Li,T.
  TITLE     Risk of migraine contributed by genetic polymorphisms of ANKDD1B
            gene: a case-control study based on Chinese Han population
  JOURNAL   Neurol Sci 43 (4), 2735-2743 (2022)
   PUBMED   34669083
  REMARK    GeneRIF: Risk of migraine contributed by genetic polymorphisms of
            ANKDD1B gene: a case-control study based on Chinese Han population.
REFERENCE   2  (bases 1 to 2575)
  AUTHORS   Tan,Z., Zeng,H., Xu,Z., Tian,Q., Gao,X., Zhou,C., Zheng,Y.,
            Wang,J., Ling,G., Wang,B., Yang,Y. and Ma,L.
  TITLE     Identification of ANKDD1B variants in an ankylosing spondylitis
            pedigree and a sporadic patient
  JOURNAL   BMC Med Genet 19 (1), 111 (2018)
   PUBMED   29976160
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2575)
  AUTHORS   Schmutz,J., Martin,J., Terry,A., Couronne,O., Grimwood,J.,
            Lowry,S., Gordon,L.A., Scott,D., Xie,G., Huang,W., Hellsten,U.,
            Tran-Gyamfi,M., She,X., Prabhakar,S., Aerts,A., Altherr,M.,
            Bajorek,E., Black,S., Branscomb,E., Caoile,C., Challacombe,J.F.,
            Chan,Y.M., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Glavina,T., Gomez,M., Gonzales,E., Goodstein,D.,
            Grigoriev,I., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Israni,S.,
            Jett,J., Kadner,K., Kimball,H., Kobayashi,A., Lopez,F., Lou,Y.,
            Martinez,D., Medina,C., Morgan,J., Nandkeshwar,R., Noonan,J.P.,
            Pitluck,S., Pollard,M., Predki,P., Priest,J., Ramirez,L.,
            Retterer,J., Rodriguez,A., Rogers,S., Salamov,A., Salazar,A.,
            Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N., Wheeler,J.,
            Wu,K., Yang,J., Dickson,M., Cheng,J.F., Eichler,E.E., Olsen,A.,
            Pennacchio,L.A., Rokhsar,D.S., Richardson,P., Lucas,S.M.,
            Myers,R.M. and Rubin,E.M.
  TITLE     The DNA sequence and comparative analysis of human chromosome 5
  JOURNAL   Nature 431 (7006), 268-274 (2004)
   PUBMED   15372022
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010245.4.
            
            On Dec 23, 2019 this sequence version replaced NM_001276713.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            CCDS Note: This CCDS representation lacks full-length human
            transcript support. Its exon combination is therefore inferred, but
            it is supported by partial human transcripts, including DY655290.1
            and DY655683.1, and by RNA-seq data.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2154405,
                              SAMEA2159080 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000601380.4/ ENSP00000471417.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-375               AC010245.4         45703-46077
            376-479             AC010245.4         51054-51157
            480-578             AC010245.4         54565-54663
            579-677             AC010245.4         59897-59995
            678-782             AC010245.4         60101-60205
            783-881             AC010245.4         69148-69246
            882-980             AC010245.4         70034-70132
            981-1079            AC010245.4         87392-87490
            1080-1178           AC010245.4         90279-90377
            1179-1277           AC010245.4         93533-93631
            1278-1373           AC010245.4         97644-97739
            1374-1575           AC010245.4         101042-101243
            1576-1707           AC010245.4         103502-103633
            1708-2575           AC010245.4         105229-106096
FEATURES             Location/Qualifiers
     source          1..2575
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q13.3"
     gene            1..2575
                     /gene="ANKDD1B"
                     /note="ankyrin repeat and death domain containing 1B"
                     /db_xref="GeneID:728780"
                     /db_xref="HGNC:HGNC:32525"
                     /db_xref="MIM:619920"
     exon            1..375
                     /gene="ANKDD1B"
                     /inference="alignment:Splign:2.1.0"
     CDS             183..1769
                     /gene="ANKDD1B"
                     /note="ankyrin repeat and death domain-containing protein
                     ENSP00000345065"
                     /codon_start=1
                     /product="ankyrin repeat and death domain-containing
                     protein 1B"
                     /protein_id="NP_001263642.1"
                     /db_xref="CCDS:CCDS64180.1"
                     /db_xref="GeneID:728780"
                     /db_xref="HGNC:HGNC:32525"
                     /db_xref="MIM:619920"
                     /translation="MDPAGRARGQGATAGGLLLRAAAAAKGLREDLWGAAALPWRSLS
                     RIPKREGLGEEDTAVAGHELLLPNERSFQNAAKSNNLDLMEKLFEKKVNINVVNNMNR
                     TALHFAVGRNHLSAVDFLLKHKARVDVADKHGLTVIHLAAWSGSLEVMLMLVKAGADQ
                     RAKNQDGMSALHFATQSNHVRIVEYLIQDLHLKDLNQPDEKGRKPFLLAAERGHVEMI
                     EKLTFLNLHTSEKDKGGNTALHLAAKHGHSPAVQVLLAQWQDINEMNELNISSLQIAT
                     RNGHASLVNFLLSENVDLHQKVEPKESPLHLVVINNHITVVNSLLSAQHDIDILNQKQ
                     QTPLHVAADRGNVELVETLLKAGCDLKAVDKQGKTALAVASRSNHSLVVGMLIKAERY
                     YAWREEHHESIRDPSTGFTLTFKQDHSLETRHIRTLLWDLAYHQLKANEWQRLARSWN
                     FTDDQIRAIEEQWSGNESFREHGHRALLIWLHGTLMTQGDPAKQLYEELVHAGFPKLA
                     EKTRHFKSKTDSNSKKCVVS"
     exon            376..479
                     /gene="ANKDD1B"
                     /inference="alignment:Splign:2.1.0"
     exon            480..578
                     /gene="ANKDD1B"
                     /inference="alignment:Splign:2.1.0"
     exon            579..677
                     /gene="ANKDD1B"
                     /inference="alignment:Splign:2.1.0"
     exon            678..782
                     /gene="ANKDD1B"
                     /inference="alignment:Splign:2.1.0"
     exon            783..881
                     /gene="ANKDD1B"
                     /inference="alignment:Splign:2.1.0"
     exon            882..980
                     /gene="ANKDD1B"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1079
                     /gene="ANKDD1B"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1178
                     /gene="ANKDD1B"
                     /inference="alignment:Splign:2.1.0"
     exon            1179..1277
                     /gene="ANKDD1B"
                     /inference="alignment:Splign:2.1.0"
     exon            1278..1373
                     /gene="ANKDD1B"
                     /inference="alignment:Splign:2.1.0"
     exon            1374..1575
                     /gene="ANKDD1B"
                     /inference="alignment:Splign:2.1.0"
     exon            1576..1707
                     /gene="ANKDD1B"
                     /inference="alignment:Splign:2.1.0"
     exon            1708..2575
                     /gene="ANKDD1B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2553..2558
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANKDD1B"
                     /note="hexamer: AATAAA"
     polyA_site      2575
                     /gene="ANKDD1B"
                     /note="major polyA site"
ORIGIN      
        1 gttgcccagc gaaccgccac aacagagagc ggactcgatc ctgcgctccg gccgggctga
       61 cctgcctgcg tccagccccc gcgccctggg cctgcctggg tctggatctg tgtccgagtc
      121 tgggtctgga tctgggtccg agtctgggtc tggccctgcg ctcagggccc gcggaggaga
      181 ctatggaccc cgccgggcgc gcccggggcc aaggggccac ggcagggggg ctgctgctcc
      241 gggctgctgc ggccgccaag ggtctcaggg aagacctgtg gggcgcggcc gccctgcctt
      301 ggaggagcct gtcccggatc ccgaagcggg agggtcttgg agaggaggac acagcagttg
      361 ccggacacga gctcctactc ccaaatgaga gaagctttca gaatgctgct aaaagcaata
      421 atttggatct tatggagaag ctgtttgaaa agaaggttaa cattaatgtt gtgaacaata
      481 tgaaccgcac agccctgcat tttgcagtgg ggagaaatca tttatctgca gtggatttct
      541 tgcttaaaca caaggccagg gtggatgttg ctgataagca cggcttgaca gtaattcacc
      601 ttgcagcctg gtctgggagc cttgaggtca tgctcatgct ggttaaagct ggagcagacc
      661 agagagccaa gaatcaggat ggaatgagcg ccctccactt tgccactcag agcaatcatg
      721 tgcgcatcgt ggagtatctt attcaagatc tgcacctcaa ggacctgaac cagcctgatg
      781 agaaaggaag aaaaccattt cttttggcag ctgagagggg ccatgttgaa atgatagaaa
      841 aacttacctt cctaaacctg catacttcag aaaaggacaa ggggggaaac actgccttgc
      901 acctcgctgc gaagcatggt cacagtcctg cagtgcaggt gctgctagcc cagtggcaag
      961 acataaatga gatgaatgag ctcaatatca gtagtttgca gatagcaacc aggaacggcc
     1021 atgcatccct tgtcaacttt cttctcagtg agaacgttga tctgcaccag aaagtggaac
     1081 ctaaggagtc ccctcttcat ttagttgtta tcaacaacca catcacggtt gtaaacagtt
     1141 tattaagtgc acagcatgat attgacatct taaatcagaa gcagcaaacc cctctgcatg
     1201 tagctgctga tcgtggaaat gtggaactgg tggaaaccct gctgaaggca ggctgtgact
     1261 tgaaggctgt tgacaagcaa ggaaagactg ccctggctgt ggcctccagg agcaaccata
     1321 gccttgtcgt gggcatgctc attaaagcag agagatacta cgcctggaga gaggagcatc
     1381 atgagagcat cagggacccg tcaacaggct ttactctgac attcaagcaa gatcacagtc
     1441 tggagaccag acacattcgc acgcttctct gggacctggc ttaccatcag ctgaaggcca
     1501 atgagtggca gaggctggcc cgttcgtgga actttacaga tgaccagatt agagccattg
     1561 aggagcagtg gtcgggaaat gaaagcttcc gtgaacatgg ccacagggct ctgcttatct
     1621 ggctacacgg gaccctgatg actcagggtg acccggccaa gcaactgtat gaagagctgg
     1681 tacacgcagg tttcccaaaa ctagctgaaa agactcgtca tttcaaaagc aaaactgact
     1741 caaactccaa gaaatgtgta gtttcataaa tgcctaaaga aattgtattt acatgatttt
     1801 ccactcagca ttcagttctt ttaatgccat aaatttcttc tagcagtagc actgattttc
     1861 aactatgatg atggtggtga cagggaactc taacagatga aagaagagta ataccatgat
     1921 acttttcaac cactaaaaag tcaaatatag ttttttttgc tgagggcaag ttgtatgtga
     1981 ttttcccatt tctatcaatc atttgatgta atccatgtaa taagataatc taggacggtt
     2041 ttgtatgtca tgttttttta aaaaactcat gggagcagca tcatggtaca gtaaaaaaac
     2101 aagggttttt ataatagaca aatatggttt tgaacttggt tttgccactt attagatgtg
     2161 aacctttggg catgttaatg ttgtttacgt tcttagatct tcagtttcct tctctataaa
     2221 ctgggagaga tgtctattta atccataggg ttggaatgaa gatgaaggga aaatgcctgt
     2281 gtagcctcac gcccatagta cggaaatcaa ctgctatttc tctttcagta agagaaactg
     2341 ggtttggaat ttatagtcat tgttgacttt aaatcacaca ttttgtgtaa tatattactt
     2401 aggaaagacc agaagtatgt acaccatttt tttttttttt taaatctctt ggtgatgtaa
     2461 ttacagatga ttattttctt tgtacttttg ggtacattcc attctttttt tcacaaagaa
     2521 catgcattat ttttgtaatc taagagttat gaaataaatg taaaattgag tgtca
//
