LOCUS       NM_020987              17019 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens ankyrin 3 (ANK3), transcript variant 1, mRNA.
ACCESSION   NM_020987
VERSION     NM_020987.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 17019)
  AUTHORS   Furia,F., Levy,A.M., Theunis,M., Bamshad,M.J., Bartos,M.N.,
            Bijlsma,E.K., Brancati,F., Cejudo,L., Chong,J.X., De Luca,C.,
            Dean,S.J., Egense,A., Goel,H., Guenzel,A.J., Huffmeier,U.,
            Legius,E., Mancini,G.M.S., Marcos-Alcalde,I., Niclass,T.,
            Planes,M., Redon,S., Ros-Pardo,D., Rouault,K., Schot,R.,
            Schuhmann,S., Shen,J.J., Tao,A.M., Thiffault,I., Van Esch,H.,
            Wentzensen,I.M., Barakat,T.S., Moller,R.S., Gomez-Puertas,P.,
            Chung,W.K., Gardella,E. and Tumer,Z.
  TITLE     The phenotypic and genotypic spectrum of individuals with mono- or
            biallelic ANK3 variants
  JOURNAL   Clin Genet 106 (5), 574-584 (2024)
   PUBMED   38988293
  REMARK    GeneRIF: The phenotypic and genotypic spectrum of individuals with
            mono- or biallelic ANK3 variants.
REFERENCE   2  (bases 1 to 17019)
  AUTHORS   Yang,Y., Zhu,Z., Hui,L. and Sun,P.
  TITLE     Effects of CACNA1C and ANK3 on cognitive function in patients with
            bipolar disorder
  JOURNAL   Prog Neuropsychopharmacol Biol Psychiatry 133, 111016 (2024)
   PUBMED   38657895
  REMARK    GeneRIF: Effects of CACNA1C and ANK3 on cognitive function in
            patients with bipolar disorder.
REFERENCE   3  (bases 1 to 17019)
  AUTHORS   Shen,G., Chen,L., Liu,Y., Zhu,Q., Kang,Y., Luo,X., Wang,F. and
            Wang,W.
  TITLE     ANK3 rs10994336 and ZNF804A rs7597593 polymorphisms: genetic
            interaction for emotional and behavioral symptoms of alcohol
            withdrawal syndrome
  JOURNAL   BMC Psychiatry 24 (1), 335 (2024)
   PUBMED   38702695
  REMARK    GeneRIF: ANK3 rs10994336 and ZNF804A rs7597593 polymorphisms:
            genetic interaction for emotional and behavioral symptoms of
            alcohol withdrawal syndrome.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 17019)
  AUTHORS   Kong,C., Qu,X., Liu,M., Xu,W., Chen,D., Zhang,Y., Zhang,S., Zhu,F.,
            Liu,Z., Li,J., Huang,C. and Wang,C.
  TITLE     Dynamic interactions between E-cadherin and Ankyrin-G mediate
            epithelial cell polarity maintenance
  JOURNAL   Nat Commun 14 (1), 6860 (2023)
   PUBMED   37891324
  REMARK    GeneRIF: Dynamic interactions between E-cadherin and Ankyrin-G
            mediate epithelial cell polarity maintenance.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 17019)
  AUTHORS   Aas,M., Andreassen,O.A., Gjerstad,J., Rodevand,L., Hjell,G.,
            Johansen,I.T., Lunding,S.H., Ormerod,M.B.E.G., Lagerverg,T.V.,
            Steen,N.E., Djurovic,S. and Akkouh,I.
  TITLE     Expression of ANK3 moderates the association between childhood
            trauma and affective traits in severe mental disorders
  JOURNAL   Sci Rep 13 (1), 13845 (2023)
   PUBMED   37620394
  REMARK    GeneRIF: Expression of ANK3 moderates the association between
            childhood trauma and affective traits in severe mental disorders.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 17019)
  AUTHORS   Mohler,P.J., Gramolini,A.O. and Bennett,V.
  TITLE     The ankyrin-B C-terminal domain determines activity of ankyrin-B/G
            chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and
            ryanodine receptor distribution in ankyrin-B (-/-) neonatal
            cardiomyocytes
  JOURNAL   J Biol Chem 277 (12), 10599-10607 (2002)
   PUBMED   11781319
  REMARK    GeneRIF: The ankyrin-B C-terminal domain determines activity of
            ankyrin-B/G chimeras
REFERENCE   7  (bases 1 to 17019)
  AUTHORS   Komada,M. and Soriano,P.
  TITLE     [Beta]IV-spectrin regulates sodium channel clustering through
            ankyrin-G at axon initial segments and nodes of Ranvier
  JOURNAL   J Cell Biol 156 (2), 337-348 (2002)
   PUBMED   11807096
REFERENCE   8  (bases 1 to 17019)
  AUTHORS   Devarajan,P., Stabach,P.R., Mann,A.S., Ardito,T., Kashgarian,M. and
            Morrow,J.S.
  TITLE     Identification of a small cytoplasmic ankyrin (AnkG119) in the
            kidney and muscle that binds beta I sigma spectrin and associates
            with the Golgi apparatus
  JOURNAL   J Cell Biol 133 (4), 819-830 (1996)
   PUBMED   8666667
REFERENCE   9  (bases 1 to 17019)
  AUTHORS   Kapfhamer,D., Miller,D.E., Lambert,S., Bennett,V., Glover,T.W. and
            Burmeister,M.
  TITLE     Chromosomal localization of the ankyrinG gene (ANK3/Ank3) to human
            10q21 and mouse 10
  JOURNAL   Genomics 27 (1), 189-191 (1995)
   PUBMED   7665168
REFERENCE   10 (bases 1 to 17019)
  AUTHORS   Kordeli,E., Lambert,S. and Bennett,V.
  TITLE     AnkyrinG. A new ankyrin gene with neural-specific isoforms
            localized at the axonal initial segment and node of Ranvier
  JOURNAL   J Biol Chem 270 (5), 2352-2359 (1995)
   PUBMED   7836469
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BP202757.1, U13616.1,
            AL359377.18, AL592430.8, AC023904.10 and AW451432.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_020987.4.
            
            Summary: Ankyrins are a family of proteins that are believed to
            link the integral membrane proteins to the underlying
            spectrin-actin cytoskeleton and play key roles in activities such
            as cell motility, activation, proliferation, contact, and the
            maintenance of specialized membrane domains. Multiple isoforms of
            ankyrin with different affinities for various target proteins are
            expressed in a tissue-specific, developmentally regulated manner.
            Most ankyrins are typically composed of three structural domains:
            an amino-terminal domain containing multiple ankyrin repeats; a
            central region with a highly conserved spectrin binding domain; and
            a carboxy-terminal regulatory domain which is the least conserved
            and subject to variation. Ankyrin 3 is an immunologically distinct
            gene product from ankyrins 1 and 2, and was originally found at the
            axonal initial segment and nodes of Ranvier of neurons in the
            central and peripheral nervous systems. Multiple transcript
            variants encoding different isoforms have been found for this
            gene.[provided by RefSeq, Feb 2011].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U13616.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000280772.7/ ENSP00000280772.1
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-265               BP202757.1         177-441
            266-969             U13616.1           121-824
            970-982             AL359377.18        79160-79172         c
            983-1554            U13616.1           838-1409
            1555-1555           AL359377.18        21138-21138         c
            1556-2799           U13616.1           1411-2654
            2800-2800           AL592430.8         130730-130730       c
            2801-3441           U13616.1           2656-3296
            3442-3466           AL592430.8         67281-67305         c
            3467-4589           U13616.1           3322-4444
            4590-4590           AL592430.8         41092-41092         c
            4591-5058           U13616.1           4446-4913
            5059-12093          AL592430.8         27532-34566         c
            12094-13802         U13616.1           11949-13657
            13803-16861         AC023904.10        14080-17138
            16862-17019         AW451432.1         16-173              c
FEATURES             Location/Qualifiers
     source          1..17019
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q21.2"
     gene            1..17019
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /note="ankyrin 3"
                     /db_xref="GeneID:288"
                     /db_xref="HGNC:HGNC:494"
                     /db_xref="MIM:600465"
     exon            1..451
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     CDS             338..13471
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ankyrin 3, node of Ranvier (ankyrin G)"
                     /codon_start=1
                     /product="ankyrin-3 isoform 1"
                     /protein_id="NP_066267.2"
                     /db_xref="CCDS:CCDS7258.1"
                     /db_xref="GeneID:288"
                     /db_xref="HGNC:HGNC:494"
                     /db_xref="MIM:600465"
                     /translation="MAHAASQLKKNRDLEINAEEEPEKKRKHRKRSRDRKKKSDANAS
                     YLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDA
                     ATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLL
                     DNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAA
                     ALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVAS
                     KRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNG
                     LSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKAN
                     PNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVS
                     QLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISAR
                     LGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGF
                     TPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASP
                     HAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSL
                     LLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHY
                     GNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNT
                     ALGIARRLGYISVVDTLKIVTEETMTTTTVTEKHKMNVPETMNEVLDMSDDEVRKANA
                     PEMLSDGEYISDVEEGEDAMTGDTDKYLGPQDLKELGDDSLPAEGYMGFSLGARSASL
                     RSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQHLTFTREFDSDSLRHYSWAADTLDN
                     VNLVSSPIHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKL
                     ANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETW
                     KEHQFDSKNEDLTELLNGMDEELDSPEELGKKRICRIITKDFPQYFAVVSRIKQESNQ
                     IGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPDEIVKKILGNKATFSPIVT
                     VEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDTTPNLRLLCSITGGTSPAQWEDITG
                     TTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLATQLYRELICVPYMAKFVVFAKM
                     NDPVESSLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTK
                     GGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKTTKGLPQTAVCNLNITL
                     PAHKKETESDQDDEIEKTDRRQSFASLALRKRYSYLTEPGMIERSTGATRSLPTTYSY
                     KPFFSTRPYQSWTTAPITVPGPAKSGFTSLSSSSSNTPSASPLKSIWSVSTPSPIKST
                     LGASTTSSVKSISDVASPIRSFRTMSSPIKTVVSQSPYNIQVSSGTLARAPAVTEATP
                     LKGLASNSTFSSRTSPVTTAGSLLERSSITMTPPASPKSNINMYSSSLPFKSIITSAA
                     PLISSPLKSVVSPVKSAVDVISSAKITMASSLSSPVKQMPGHAEVALVNGSISPLKYP
                     SSSTLINGCKATATLQEKISSATNSVSSVVSAATDTVEKVFSTTTAMPFSPLRSYVSA
                     APSAFQSLRTPSASALYTSLGSSISATTSSVTSSIITVPVYSVVNVLPEPALKKLPDS
                     NSFTKSAAALLSPIKTLTTETHPQPHFSRTSSPVKSSLFLAPSALKLSTPSSLSSSQE
                     ILKDVAEMKEDLMRMTAILQTDVPEEKPFQPELPKEGRIDDEEPFKIVEKVKEDLVKV
                     SEILKKDVCVDNKGSPKSPKSDKGHSPEDDWIEFSSEEIREARQQAAASQSPSLPERV
                     QVKAKAASEKDYNLTKVIDYLTNDIGSSSLTNLKYKFEDAKKDGEERQKRVLKPAIAL
                     QEHKLKMPPASMRTSTSEKELCKMADSFFGTDTILESPDDFSQHDQDKSPLSDSGFET
                     RSEKTPSAPQSAESTGPKPLFHEVPIPPVITETRTEVVHVIRSYDPSAGDVPQTQPEE
                     PVSPKPSPTFMELEPKPTTSSIKEKVKAFQMKASSEEDDHNRVLSKGMRVKEETHITT
                     TTRMVYHSPPGGEGASERIEETMSVHDIMKAFQSGRDPSKELAGLFEHKSAVSPDVHK
                     SAAETSAQHAEKDNQMKPKLERIIEVHIEKGNQAEPTEVIIRETKKHPEKEMYVYQKD
                     LSRGDINLKDFLPEKHDAFPCSEEQGQQEEEELTAEESLPSYLESSRVNTPVSQEEDS
                     RPSSAQLISDDSYKTLKLLSQHSIEYHDDELSELRGESYRFAEKMLLSEKLDVSHSDT
                     EESVTDHAGPPSSELQGSDKRSREKIATAPKKEILSKIYKDVSENGVGKVSKDEHFDK
                     VTVLHYSGNVSSPKHAMWMRFTEDRLDRGREKLIYEDRVDRTVKEAEEKLTEVSQFFR
                     DKTEKLNDELQSPEKKARPKNGKEYSSQSPTSSSPEKVLLTELLASNDEWVKARQHGP
                     DGQGFPKAEEKAPSLPSSPEKMVLSQQTEDSKSTVEAKGSISQSKAPDGPQSGFQLKQ
                     SKLSSIRLKFEQGTHAKSKDMSQEDRKSDGQSRIPVKKIQESKLPVYQVFAREKQQKA
                     IDLPDESVSVQKDFMVLKTKDEHAQSNEIVVNDSGSDNVKKQRTEMSSKAMPDSFSEQ
                     QAKDLACHITSDLATRGPWDKKVFRTWESSGATNNKSQKEKLSHVLVHDVRENHIGHP
                     ESKSVDQKNEFMSVTERERKLLTNGSLSEIKEMTVKSPSKKVLYREYVVKEGDHPGGL
                     LDQPSRRSESSAVSHIPVRVADERRMLSSNIPDGFCEQSAFPKHELSQKLSQSSMSKE
                     TVETQHFNSIEDEKVTYSEISKVSKHQSYVGLCPPLEETETSPTKSPDSLEFSPGKES
                     PSSDVFDHSPIDGLEKLAPLAQTEGGKEIKTLPVYVSFVQVGKQYEKEIQQGGVKKII
                     SQECKTVQETRGTFYTTRQQKQPPSPQGSPEDDTLEQVSFLDSSGKSPLTPETPSSEE
                     VSYEFTSKTPDSLIAYIPGKPSPIPEVSEESEEEEQAKSTSLKQTTVEETAVEREMPN
                     DVSKDSNQRPKNNRVAYIEFPPPPPLDADQIESDKKHHYLPEKEVDMIEVNLQDEHDK
                     YQLAEPVIRVQPPSPVPPGADVSDSSDDESIYQPVPVKKYTFKLKEVDDEQKEKPKAS
                     AEKASNQKELESNGSGKDNEFGLGLDSPQNEIAQNGNNDQSITECSIATTAEFSHDTD
                     ATEIDSLDGYDLQDEDDGLTESDSKLPIQAMEIKKDIWNTEGILKPADRSFSQSKLEV
                     IEEEGKVGPDEDKPPSKSSSSEKTPDKTDQKSGAQFFTLEGRHPDRSVFPDTYFSYKV
                     DEEFATPFKTVATKGLDFDPWSNNRGDDEVFDSKSREDETKPFGLAVEDRSPATTPDT
                     TPARTPTDESTPTSEPNPFPFHEGKMFEMTRSGAIDMSKRDFVEERLQFFQIGEHTSE
                     GKSGDQGEGDKSMVTATPQPQSGDTTVETNLERNVETPTVEPNPSIPTSGECQEGTSS
                     SGSLEKSAAATNTSKVDPKLRTPIKMGISASTMTMKKEGPGEITDKIEAVMTSCQGLE
                     NETITMISNTANSQMGVRPHEKHDFQKDNFNNNNNLDSSTIQTDNIMSNIVLTEHSAP
                     TCTTEKDNPVKVSSGKKTGVLQGHCVRDKQKVLGEQQKTKELIGIRQKSKLPIKATSP
                     KDTFPPNHMSNTKASKMKQVSQSEKTKALTTSSCVDVKSRIPVKNTHRDNIIAVRKAC
                     ATQKQGQPEKGKAKQLPSKLPVKVRSTCVTTTTTTATTTTTTTTTTTTSCTVKVRKSQ
                     LKEVCKHSIEYFKGISGETLKLVDRLSEEEKKMQSELSDEEESTSRNTSLSETSRGGQ
                     PSVTTKSARDKKTEAAPLKSKSEKAGSEKRSSRRTGPQSPCERTDIRMAIVADHLGLS
                     WTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTDALTSVLTKIN
                     RIDIVTLLEGPIFDYGNISGTRSFADENNVFHDPVDGWQNETSSGNLESCAQARRVTG
                     GLLDRLDDSPDQCRDSITSYLKGEAGKFEANGSHTEITPEAKTKSYFPESQNDVGKQS
                     TKETLKPKIHGSGHVEEPASPLAAYQKSLEETSKLIIEETKPCVPVSMKKMSRTSPAD
                     GKPRLSLHEEEGSSGSEQKQGEGFKVKTKKEIRHVEKKSHS"
     exon            452..553
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            554..652
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            653..751
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            752..850
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            851..1036
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1135
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1234
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            1235..1333
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            1334..1531
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            1532..1630
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            1631..1729
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            1730..1828
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            1829..2026
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            2027..2125
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            2126..2224
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            2225..2422
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            2423..2521
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            2522..2620
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            2621..2719
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            2720..2815
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            2816..2888
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            2889..2951
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            2952..3075
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            3076..3178
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            3179..3285
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            3286..3510
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            3511..3665
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            3666..3877
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            3878..4085
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            4086..4182
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            4183..4411
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            4412..4537
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            4538..4660
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            4661..4687
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            4688..4769
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            4770..12581
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            12582..12656
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            12657..12788
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            12789..12932
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            12933..13023
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            13024..13402
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            13403..13490
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     exon            13491..17019
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /inference="alignment:Splign:2.1.0"
     regulatory      14890..14895
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /note="hexamer: AATAAA"
     polyA_site      14916
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /note="major polyA site"
     regulatory      16442..16447
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /note="hexamer: AATGAA"
     polyA_site      16468
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
     regulatory      16735..16740
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /note="hexamer: AATAAA"
     polyA_site      16755
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
     regulatory      16799..16804
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /note="hexamer: AATAAA"
     polyA_site      16819
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
     polyA_site      16865
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
     polyA_site      16870
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
     regulatory      16991..16996
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
                     /note="hexamer: AGTAAA"
     polyA_site      17019
                     /gene="ANK3"
                     /gene_synonym="ANKYRIN-G; MRT37"
ORIGIN      
        1 cttagacact tccagctggt ggcaggggat acagccataa tacagcttcc tctgtcccag
       61 ctgtcttctt cactacggta aatgcattac gatggctgca ctctcctgta aaggttcagg
      121 tagaggaagg tgtaggatga agtccggaca ccatcatttg ggtttttaaa agcttcagct
      181 tctccagcat ctttgcattg tgaatatctt cctgcttcta gtcaaagctt tctctctagt
      241 gattggaatg ctgctgtaag cctgattaga ggtgcctgag gatatcacct tttacaagga
      301 agccgtgtgt gcttgagagg atctttttaa atgcattatg gctcatgcag cctcacaatt
      361 aaagaaaaac agggatttag aaatcaatgc tgaagaagag cctgagaaaa aaaggaaaca
      421 ccgcaaacgg tcccgggatc ggaagaaaaa gtctgatgcc aatgcaagtt acttaagagc
      481 agctcgagct ggacaccttg aaaaggccct cgactacata aaaaatggag ttgacatcaa
      541 catttgcaat cagaatgggt tgaacgctct ccaccttgct tccaaagaag gccatgtaga
      601 ggttgtttct gagctgctgc agagagaagc caatgtggat gcagctacaa agaaaggaaa
      661 cacagcattg cacatcgcat ctttggctgg gcaagcagag gtggtaaaag tcttggttac
      721 aaatggagcc aatgtcaatg cacaatctca gaatggtttc acgccattgt atatggcagc
      781 ccaggaaaat cacctggaag ttgtcaagtt tcttcttgac aatggtgcaa gccagagcct
      841 agccacagag gatggcttca caccattggc agtggctttg caacaaggtc acgaccaagt
      901 cgtttcgctc ctgctagaga atgacaccaa aggaaaagtg cgtctcccag ctcttcatat
      961 cgcggcccga aaagacgaca cgaaagccgc cgccctgctg ctgcagaatg acaacaatgc
     1021 agatgtggaa tcaaagagtg gcttcactcc gctccacata gctgctcact atggaaatat
     1081 caatgtagcc acgttgctgt taaaccgagc ggctgctgtg gatttcaccg caaggaatga
     1141 catcactcct ttacatgttg catcaaaaag aggaaatgca aatatggtaa aactattgct
     1201 cgatcgagga gctaaaatcg atgccaaaac cagggatggt ctgacaccac tgcactgtgg
     1261 agcaaggagt ggccacgagc aggtggtaga aatgttgctt gatcgagctg cccccattct
     1321 ttcaaaaacc aagaatggat tatctccatt gcacatggcc acacaagggg atcatttaaa
     1381 ctgcgtccag cttctcctcc agcataatgt acccgtggat gatgtcacca atgactacct
     1441 gactgcccta cacgtggctg cccactgtgg ccattacaaa gttgccaagg ttctcttgga
     1501 taagaaagct aaccccaatg ccaaagccct gaatggcttt acccctcttc atattgcctg
     1561 caagaagaat cgaattaaag taatggaact ccttctgaaa cacggtgcat ccatccaagc
     1621 tgtaaccgag tcgggcctta ccccaatcca tgttgctgcc ttcatggggc atgtaaatat
     1681 tgtatcacaa ctaatgcatc atggagcctc accaaacacc accaatgtga gaggagaaac
     1741 agcactgcac atggcagctc gctccggcca agctgaagtt gtgcggtatc tggtacaaga
     1801 cggagctcag gtagaagcta aagctaagga tgaccaaaca ccactccaca tttcagcccg
     1861 actggggaaa gcagacatag tacaacagct gttgcagcaa ggggcatctc caaatgcagc
     1921 cacaacttct gggtacaccc cacttcacct ttccgcccga gaggggcatg aggatgtggc
     1981 cgcgttcctt ttggatcatg gagcgtcttt atctataaca acaaagaaag gatttactcc
     2041 tcttcatgtg gcagcaaaat atggaaagct tgaagtcgcc aatctcctgc tacagaaaag
     2101 tgcatctcca gatgctgctg ggaagagcgg gctaacacca ctgcatgtag ctgcacatta
     2161 cgataatcag aaagtggccc ttctgctttt ggaccaagga gcctcacctc acgcagccgc
     2221 aaagaatggt tatacgccac tgcacatcgc tgccaaaaag aaccagatgg acatagcgac
     2281 aactctgctg gaatatggtg ctgatgccaa cgcagttacc cggcaaggaa ttgcttccgt
     2341 ccatctcgca gctcaggaag ggcacgtgga catggtgtcg ctgctcctcg gtagaaatgc
     2401 gaatgtgaac ctgagcaata agagcggcct gaccccactc catttggctg ctcaagaaga
     2461 tcgagtgaat gtggcagaag tcctcgtaaa ccaaggggct catgtggacg cccagacaaa
     2521 gatgggatac acaccactgc atgtgggctg ccactatgga aatatcaaga ttgttaattt
     2581 cctgctccag cattctgcaa aagttaatgc caaaacaaag aatgggtata cgccattaca
     2641 tcaagcagca cagcaggggc atacgcatat aataaatgtc ttacttcaga acaacgcctc
     2701 ccccaatgaa ctcactgtga atgggaatac tgcccttggc attgcccggc gcctcggcta
     2761 catctcagta gtggacaccc tgaagatagt gaccgaagag accatgacca caactactgt
     2821 cacagagaag cacaaaatga atgttccaga aacgatgaat gaagttcttg atatgtctga
     2881 tgatgaagtt cgtaaagcca atgcccctga aatgctcagt gatggcgaat atatctcaga
     2941 tgttgaagaa ggtgaagatg caatgaccgg ggacacagac aaatatcttg ggccacagga
     3001 ccttaaggaa ttgggtgatg attccctgcc tgcagagggt tacatgggct ttagtctcgg
     3061 agcgcgttct gccagcctcc gctccttcag ttcggatagg tcttacacct tgaacagaag
     3121 ctcctatgca cgggacagca tgatgattga agaactcctt gtgccatcca aagagcagca
     3181 tctaacattc acaagggaat ttgattcaga ttctcttaga cattacagct gggctgcaga
     3241 caccttagac aatgtcaatc ttgtttcaag ccccattcat tctgggtttc tggttagctt
     3301 tatggtggac gcgagagggg gctccatgag aggaagccgt catcacggga tgagaatcat
     3361 cattcctcca cgcaagtgta cggcccccac tcgaatcacc tgccgtttgg taaagagaca
     3421 taaactggcc aacccacccc ccatggtgga aggagaggga ttagccagta ggctggtaga
     3481 aatgggtcct gcaggggcac aatttttagg ccctgtcata gtggaaatcc ctcactttgg
     3541 gtccatgaga ggaaaagaga gagaactcat tgttcttcga agtgaaaatg gtgaaacttg
     3601 gaaggagcat cagtttgaca gcaaaaatga agatttaacc gagttactta atggcatgga
     3661 tgaagaactt gatagcccag aagagttagg gaaaaagcgt atctgcagga ttatcacgaa
     3721 agatttcccc cagtattttg cagtggtttc ccggattaag caggaaagca accagattgg
     3781 tcctgaaggt ggaattctga gcagcaccac agtgcccctt gttcaagcat ctttcccaga
     3841 gggtgcccta actaaaagaa ttcgagtggg cctccaggcc cagcctgttc cagatgaaat
     3901 tgtgaaaaag atccttggaa acaaagcaac ttttagccca attgtcactg tggaaccaag
     3961 aagacggaaa ttccataaac caatcacaat gaccattccg gtgcccccgc cctcaggaga
     4021 aggtgtatcc aatggataca aaggggacac tacacccaat ctgcgtcttc tctgtagcat
     4081 tacagggggc acttcgcctg ctcagtggga agacatcaca ggaacaactc ctttgacgtt
     4141 tataaaagat tgtgtctcct ttacaaccaa tgtttcagcc agattttggc ttgcagactg
     4201 ccatcaagtt ttagaaactg tggggttagc cacgcaactg tacagagaat tgatatgtgt
     4261 tccatatatg gccaagtttg ttgtttttgc caaaatgaat gatcccgtag aatcttcctt
     4321 gcgatgtttc tgcatgacag atgacaaagt ggacaaaact ttagagcaac aagagaattt
     4381 tgaggaagtc gcaagaagca aagatattga ggttctggaa ggaaaaccta tttatgttga
     4441 ttgttatgga aatttggccc cacttaccaa aggaggacag caacttgttt ttaactttta
     4501 ttctttcaaa gaaaatagac tgccattttc catcaagatt agagacacca gccaagagcc
     4561 ctgtggtcgt ctgtcttttc tgaaagaacc aaagacaaca aaaggactgc ctcaaacagc
     4621 ggtttgcaac ttaaatatca ctctgccagc acataaaaag gagacagagt cagatcaaga
     4681 tgatgagatt gagaaaacag atagacgaca gagcttcgca tccttagctt tacgtaagcg
     4741 ctacagctac ttgactgagc ctggaatgat tgaacggagt acaggagcaa caagatccct
     4801 ccccaccact tactcataca agccattctt ttctacaaga ccataccagt cctggacaac
     4861 agctccgatt acagtgcctg ggccagccaa gtcaggcttc acttccttat caagttcttc
     4921 ctctaatacg ccatcagctt ctccgttaaa atcaatatgg tctgtttcga caccttctcc
     4981 aatcaaatcc acattaggcg cgtcaactac atcttcagtt aaatccatta gtgacgtggc
     5041 atctccaatt agatcctttc ggacaatgtc ttcgccgata aaaactgtgg tgtcacaatc
     5101 tccatacaat atccaagttt cctctggtac cctggctaga gctccagcag tcacggaagc
     5161 tacgccctta aaagggctgg catccaattc tacgttttcc tctcgaacct ctccagtgac
     5221 tacagcaggg tctcttttgg agaggtcatc aattactatg acaccccctg cctcccccaa
     5281 atcaaacatt aatatgtatt cctcaagttt gccatttaag tcaattatta catcagcagc
     5341 accgctaata tcttcacctt taaagtcagt ggtgtctcca gttaaatcag cagttgatgt
     5401 catttcatca gccaaaatta caatggcatc ttctctctca tcacctgtga agcagatgcc
     5461 tggacatgca gaggtagcat tagtcaatgg atctatttcc cctctaaaat atccatcatc
     5521 ctcaacttta attaatggat gcaaagccac tgccacgtta caggaaaaaa tttcttctgc
     5581 tacaaactct gtgagctctg tggtcagtgc agccactgac acagttgaga aagtgttttc
     5641 taccacgact gcaatgccat tttccccact caggtcatat gtttctgcag caccatcagc
     5701 ttttcagtct ctaagaactc cttccgcaag tgcactctat acatcccttg ggtcgtcaat
     5761 atctgcaact acctcatctg taacttcatc aattataaca gtgccagtat actctgtagt
     5821 caatgttttg ccagaaccag cattaaagaa acttccagac tctaattcat ttacaaaatc
     5881 agcagcagcc ttgctgtcac ccattaaaac attgactacg gagacacatc ctcagcctca
     5941 cttcagtcga acttcatctc cagttaagtc atctttgttc cttgcaccct ctgcccttaa
     6001 gttgtctaca ccatcttctt tatcttccag tcaggagata ctaaaagatg tagctgaaat
     6061 gaaagaggac ctaatgcgga tgaccgcaat actacagaca gatgtgcctg aggagaagcc
     6121 attccaacct gaactcccaa aggaagggag aatagatgat gaagaacctt tcaaaattgt
     6181 agagaaagta aaggaagact tagtgaaagt tagtgaaatc cttaaaaagg atgtatgtgt
     6241 agataataaa ggatcaccca aatcaccaaa gagtgacaaa ggacactctc ctgaagatga
     6301 ctggatagaa tttagttcgg aagaaatccg ggaagccaga caacaagctg ctgcgagcca
     6361 gtctccatct ctgccagaga gagtgcaagt aaaagcaaaa gccgcctccg aaaaggatta
     6421 taacttgacc aaagttattg attacctaac aaatgatatt gggagtagtt cactgacaaa
     6481 cttaaaatac aagtttgagg atgcaaagaa ggatggtgag gagagacaga aaagagtttt
     6541 aaaaccagca attgctttgc aggaacacaa actcaaaatg cctccagcct ccatgaggac
     6601 ttccacctct gagaaagaat tgtgtaaaat ggctgattcc ttttttggaa cagatactat
     6661 tttagagtct cctgatgact tttctcaaca cgaccaagat aaaagtccct tgtctgacag
     6721 tggctttgaa acaagaagtg aaaagacacc ttcagcccca caaagcgctg aaagcactgg
     6781 tcctaaacca ctttttcatg aagttcccat ccctcctgtc attacagaaa caagaactga
     6841 agtggttcat gttatcagga gctatgatcc ctcagctggg gatgttcccc agacccaacc
     6901 agaggagcct gtgtcaccta aaccttcacc tacttttatg gaattggaac caaagcccac
     6961 cacctctagt attaaagaaa aggttaaagc atttcaaatg aaagccagta gtgaagaaga
     7021 tgaccacaat cgggttttaa gcaaaggcat gcgtgttaaa gaagagactc acataaccac
     7081 aaccaccaga atggtttatc attctccacc aggcggtgaa ggtgcatctg aaagaattga
     7141 agaaaccatg tcagtccatg acatcatgaa ggcctttcag tccgggcggg atccttccaa
     7201 agaactggca ggtctgtttg aacataagtc ggcagtgtct ccagatgttc acaagtctgc
     7261 tgctgaaacc tcagcccagc atgcagagaa ggacaaccaa atgaaaccca aactggagcg
     7321 tataatagaa gtccacatcg aaaaaggtaa ccaagctgag cccactgaag tcattattag
     7381 agaaaccaaa aagcatccag aaaaagaaat gtatgtatat cagaaagact tatcccgggg
     7441 agatattaac ctaaaagatt ttctgccaga aaaacacgat gcttttcctt gttcagagga
     7501 acagggtcag caagaagaag aagaacttac tgctgaagag tcattgcctt cttatctgga
     7561 gtcttccaga gtaaacactc ctgtgtccca agaagaagat agccgcccta gttctgctca
     7621 actcatatct gatgactctt ataaaacatt gaagcttttg agtcaacact caatagaata
     7681 ccatgacgat gagttgtcag aactaagagg ggagtcttac aggtttgctg agaaaatgct
     7741 tctgtcagaa aagctagatg tgtctcattc tgatactgag gaatcggtta cagaccatgc
     7801 aggaccccct agctcagagt tacaggggtc tgataagcgg tccagagaaa aaatagccac
     7861 tgcccccaaa aaagaaattc tctccaaaat ctataaagat gtttctgaaa atggtgtagg
     7921 taaagtgtct aaagatgagc attttgataa agtgacagtg ttgcactatt ctggcaatgt
     7981 tagtagtcca aaacatgcca tgtggatgcg ctttactgag gacagattag acagaggtag
     8041 agagaagttg atatatgaag atagggtgga caggactgtg aaggaggctg aagaaaaact
     8101 gactgaagtg tcacagtttt ttcgtgacaa aactgaaaag ctaaatgatg aactgcagtc
     8161 cccagagaaa aaggcacgcc ctaaaaatgg caaagaatat tcttctcaaa gccctaccag
     8221 tagcagccct gagaaagtgc tactgacaga actgctggca tccaatgatg agtgggttaa
     8281 ggcaagacag catggccctg atggacaagg cttccccaag gccgaggaga aggcacccag
     8341 tctgcccagc agcccagaga agatggttct ctcccaacag actgaggaca gcaagtccac
     8401 agtggaagcc aaaggaagta tttcacagag caaagcacca gatgggcccc agtctggatt
     8461 ccagctcaaa caatctaaac tcagttccat tagattaaaa tttgaacaag gcacacacgc
     8521 aaaaagtaag gacatgtctc aagaagacag aaagtcagat ggccagtcca gaatcccagt
     8581 taaaaaaata caggagagca agctacccgt ctaccaagtt tttgctagag aaaaacagca
     8641 gaaggccata gacctcccag atgaaagtgt atctgtgcaa aaagatttta tggtattaaa
     8701 aaccaaagat gagcatgccc aaagcaacga aattgttgta aatgattctg gctctgataa
     8761 tgtgaaaaaa cagagaactg aaatgtcaag taaagcaatg cctgactctt tttctgagca
     8821 gcaggctaaa gacttggcat gtcatataac ctcagattta gcaactaggg gaccatggga
     8881 caaaaaggtc tttagaacat gggagagttc gggagccact aacaataagt ctcagaaaga
     8941 aaaactttcg catgtacttg ttcatgatgt aagagagaat cacattggtc accctgagag
     9001 taaaagtgtt gatcaaaaga atgaatttat gtctgtgact gagagagaac gcaaattgtt
     9061 aacaaacggc tctctctcag aaattaaaga aatgactgta aaatctccct ccaaaaaagt
     9121 cttatatagg gaatatgttg tgaaagaagg ggaccatcca ggcggattgc ttgatcagcc
     9181 ttccaggagg agcgagagct cagcagtgtc acacattccc gtcagagttg ctgatgagag
     9241 gagaatgctg tcttctaata ttcccgatgg tttttgtgaa cagtcggcat ttccaaaaca
     9301 tgaactatca caaaaattgt cccagtcaag catgagtaaa gagacagttg agacacagca
     9361 ctttaattct atagaagatg aaaaagttac ctattcagaa atcagcaaag tttccaaaca
     9421 ccagagttat gtaggtttat gcccacctct cgaggaaacc gaaacctccc ccaccaaatc
     9481 tcctgattct ttagagttta gcccaggaaa ggaatctccc tctagtgatg tattcgacca
     9541 cagtcccatt gatggattgg aaaaactcgc accactagcc cagacagagg gagggaaaga
     9601 gataaaaact ttacccgttt atgtcagttt tgtacaagtg gggaagcaat atgaaaagga
     9661 gatacaacaa ggaggtgtaa aaaaaatcat aagtcaggaa tgtaagacag tacaagaaac
     9721 cagggggacc ttttatacaa ctagacagca aaagcaacct ccttctcccc aaggtagtcc
     9781 agaagatgat actctagagc aagtatcctt tctagacagc tctgggaaaa gccctttaac
     9841 cccagaaaca cccagttcag aggaagtgag ttatgaattt acatctaaga cacctgactc
     9901 gctcatagct tatataccag gcaaacccag cccaattccc gaggtttctg aggagtcaga
     9961 ggaggaggaa caggccaagt caacctccct taagcagact acagtggagg aaacagcagt
    10021 tgagcgtgaa atgcctaatg acgtgagcaa agactctaac caaagaccca aaaataacag
    10081 agttgcctat attgaatttc cccctcctcc accactggat gcggaccaga ttgagtcaga
    10141 taagaagcat cattatctcc cagaaaaaga ggttgacatg attgaagtca atctgcaaga
    10201 tgagcatgac aagtaccagc tggctgaacc tgtcattaga gtgcagccac cttcaccagt
    10261 tcctcccggg gcagacgtca gtgattcaag cgatgacgaa tctatttatc agccagtccc
    10321 agttaaaaaa tataccttca aattaaagga agtggacgat gaacaaaaag aaaaacccaa
    10381 agcttctgct gaaaaggctt ccaaccagaa agaactggaa agtaatggat ctggaaaaga
    10441 taatgaattt ggccttggcc ttgattcacc tcagaatgaa attgcccaga atgggaacaa
    10501 cgaccagtcc atcacagagt gttccattgc caccacagca gagttttctc atgacacgga
    10561 tgccacagag atcgactctc tggatggcta tgacctgcaa gatgaagatg atggcttgac
    10621 agagagtgat tctaaactcc caattcaagc catggaaatt aagaaagata tctggaacac
    10681 agagggcatt ctgaagccag ctgaccgctc ttttagccaa agtaaacttg aagttatcga
    10741 ggaggaggga aaggtgggac cagatgagga caagccacct tctaaaagtt cttcatctga
    10801 aaagactcct gataagactg atcagaagtc aggggcccag ttcttcacac tggaaggcag
    10861 acatcctgac agatcagtgt ttcctgatac ttacttcagt tacaaagtag atgaagaatt
    10921 tgccactcct tttaaaacag tagctaccaa aggtctagat tttgaccctt ggtctaataa
    10981 ccgaggggat gatgaagttt ttgacagtaa atcacgggaa gatgaaacta agccatttgg
    11041 gctggcggta gaagaccgct ctccagcaac aacccctgat acaacgccag ccagaacgcc
    11101 aactgatgaa agtaccccaa ctagtgagcc taaccccttc ccatttcatg aaggaaaaat
    11161 gtttgagatg actcgcagtg gtgcaattga catgagcaag agggattttg ttgaagagag
    11221 gctccaattt ttccagattg gtgagcatac ttctgaaggg aagtcagggg accaggggga
    11281 aggggataaa agtatggtca ctgccacacc acagccacag tcaggggaca ccactgtaga
    11341 aaccaatcta gagagaaatg tagagacacc tacagtggaa cctaacccca gcatcccgac
    11401 cagcggagag tgtcaggaag gcacatccag tagtggctcc ctggagaaat cagcagcagc
    11461 cactaacacc tctaaagttg accccaagtt gcgcacgcct ataaaaatgg gaatttctgc
    11521 atccaccatg accatgaaga aagaaggccc tggagaaata acagataaga tagaagcggt
    11581 gatgaccagt tgtcagggat tagaaaatga aactataaca atgatttcaa atacagccaa
    11641 tagccagatg ggcgttaggc cccatgaaaa acatgatttt caaaaagata actttaataa
    11701 caacaacaat ttggattctt ccactataca gacagataac attatgagta atatagttct
    11761 gacagaacat tctgcaccca cttgtaccac agagaaagat aacccagtga aagtctcatc
    11821 aggaaaaaag acaggggtac tacaaggaca ctgtgtaaga gataagcaga aagttcttgg
    11881 agaacagcaa aaaacaaagg aattgatagg gattaggcaa aaatccaaac ttcccataaa
    11941 ggccacttca ccaaaagata ccttcccacc gaaccatatg tcaaacacta aagcaagtaa
    12001 aatgaagcag gttagtcaat ccgagaaaac caaagccctt actacttctt catgtgtaga
    12061 tgtaaagtcc agaattccag tgaaaaacac acacagggat aacataattg cagttagaaa
    12121 agcatgtgcc acacaaaagc aagggcagcc agagaaaggc aaggccaaac agcttccatc
    12181 caagttgcca gtaaaggtaa gatccacctg tgtcactacc accaccacca ctgccaccac
    12241 caccaccact accaccacta ccaccaccac cagctgcaca gttaaagtta ggaaaagtca
    12301 gctcaaggaa gtatgtaaac attccattga atattttaag ggaattagtg gtgagacctt
    12361 aaagcttgtg gaccgcctct ctgaagaaga aaaaaagatg cagtccgagt tgtccgatga
    12421 ggaagaaagt acctcaagaa acacgtcgtt gtccgagact tcccggggtg gccagccttc
    12481 ggttacaacg aagtctgcta gagataagaa aacagaggca gcacctttaa aatcaaagag
    12541 tgaaaaggcc ggcagtgaga aaaggagcag tagaaggact ggtccacaga gtccatgtga
    12601 acggacagat atcaggatgg caatagtagc cgatcacctg ggacttagtt ggacagaact
    12661 ggcaagggaa ctgaattttt cagtggatga aatcaatcaa atacgtgtgg aaaatccaaa
    12721 ttctttaatt tctcagagct tcatgttatt aaaaaaatgg gttaccagag acggaaaaaa
    12781 tgccacaact gatgccttaa cttcggtctt gacaaaaatt aatcgaatag atatagtgac
    12841 actgctagaa ggaccaatat ttgattatgg aaatatttca ggcaccagaa gttttgcaga
    12901 tgagaacaat gttttccatg accctgttga tggttggcag aatgagacat caagtggaaa
    12961 cctagagtcc tgcgctcaag ctcgaagagt aactggtggg ttactagatc gactggatga
    13021 cagccctgac cagtgtagag attccattac ctcatatctc aaaggagaag ctggcaaatt
    13081 tgaagcaaat ggaagccata cagaaatcac tccagaagca aagacaaaat cttactttcc
    13141 agaatcccaa aatgatgtag gaaaacagag taccaaggaa actctgaaac caaaaataca
    13201 tggatctggt catgttgaag aaccagcatc accactagca gcatatcaga aatctctaga
    13261 agaaaccagc aagcttataa tagaagagac taaaccctgt gtgcctgtca gtatgaaaaa
    13321 gatgagtagg acttctccag cagatggcaa gccaaggctt agcctccatg aagaagaggg
    13381 gtccagtggg tctgagcaaa agcagggaga aggttttaag gtgaaaacga agaaagaaat
    13441 ccggcatgtg gaaaagaaga gccactcgta acagcgaacg gtcagtcaag gatcataagt
    13501 ttttactgcc agtattgaga aattcgtgga agaaatgtca gcaggaagta aaaattcacc
    13561 gagaagtgtg tgtgtgttcg ctgcttccac acattaatgg catgattttt tttatgcaaa
    13621 aagaaaagaa aagaaaacca cccacatttt aatttagcat gagccaattt acagagcatg
    13681 gaaatcactt tcatttccgg attggcgcgt gtgcaattag caatgcagtg tatatacaag
    13741 aagccatgct gttaacagtt tatctcaagt aatttggtgt catttacaaa aggaagaaat
    13801 tcctgccatc agaagggaca gaaggagatg gaatgatcaa atcacagaga aacactaaaa
    13861 ttactaaatc tacaacagct cgccttattt ttcttggacc caaactgtca gggtataaac
    13921 actatttgtt tcttttttaa aacatcgata gttttgctgt aaataataac actgtataaa
    13981 ttctaacaga aaaatagaat aaaatgttga taaggcactg cctcttagaa cacaaacaga
    14041 atattgcaaa tgcatttaac aaataggggt ctcaagtgac ttcaccctag aagaggaggg
    14101 agggattctg ggtgggggtg actcttcact gattcttgta tattagcaat tataatgttt
    14161 gtatatgcaa aactgctagc ttgattttaa aaaaaaacaa atctttaaaa tctgctgcaa
    14221 atttaaataa ttcccaaaat gaggaattct gtagttctgt gaaaaatttt tttcttcaga
    14281 atactaatat tttgatgcat gtgtatcacc ttattttgat taaatctttt ccaattttgc
    14341 aaacactaca gtatactgca acacaaaaga ttttatctgt aaacacaaag cccttcatct
    14401 aatatttgtt gctattgcca atttttcaat gaaatgacct aaaaacaaca aaaaaaaata
    14461 acctatacgg tagttgcttt agggggtggg gggatgctat ctgttagtgc ttaaaagggg
    14521 gtaaatgctt gccgctttag aggtggatgg tgctcataaa aggccccagt cgggggtatt
    14581 taaaaaggac tgaacagaaa tccttagcta gtagaatggc agcacgctgt aaaattatta
    14641 ctgtattgtg tactggctat aagatgtaga cacctttcag taagccaatc atttgtaacc
    14701 attctagcag tgtcatatta ggttaataag gctgctgtgt tttaaagggc atttttattt
    14761 gggttttggt gaaattcttt aatttgttga ttatattcac ataaaatcag cattcattga
    14821 cacatagctc taatgacata tgtatgaaaa accatacact ggatgaccta gtcgattatt
    14881 taagcataaa ataaattgtg ttaaactctt cacctatctg tgctctacag tctccttgtg
    14941 ttttctggca aaaggtagtt gtctaatccc ttgtcatatg agtcctggcc aatccacccc
    15001 attggtcctc tttgtgcctc tgtggtcact gaagagataa tctctaacat tcatatgtgc
    15061 cctgcaagct cccagcttat aaattctgtg catttcatgg gggagccaag aattaaagat
    15121 taattgacaa gtaagctttg cccacatctg ttcaggcctt cttgaaaagt gaagaattgg
    15181 agatactata gccagcatgt caaaaagttg actggcactt ctaggaacca tcaacatgca
    15241 gttgctttta gcccacagag cttgtttttg ttttgtttta ttaatttaca tttattgtcc
    15301 attcttacaa gttgggacat ttcacataat taagttgcta acatctctta aaaagcaaga
    15361 tttggcaaca atggacctca ttcccagaag gtaacaacct gctagagcca agttgtccct
    15421 gccctctcca gccaggtgtg gggtctacag gtatcactgc cacagcctca tttcttatat
    15481 ttgtacaacc tgactgtgaa tttgcaaccc atacactgcg tgaatctaaa ttctactgag
    15541 gcagagacca tggctgtttt aacttttatt ctagttacca gcttagcata tggtagtagt
    15601 gatagtagta actgtgatca tcatcactaa aactggagtg ctcactacat gctattctct
    15661 gttctaagca cattccattt acttacttag tcctcatatc tactttatga attaggtact
    15721 gtctttcttt gatggtaatg atccttttat aaaattaaat tagtgctaag agactttcag
    15781 caatgttata tattgcctgt ccattaaaga ttgttgccaa atggagtgag ttgtccccag
    15841 taaggattca ctatcaatgc agaagaaatg cacggataat ctactttgca taaagaatgg
    15901 ggctaggttg catctgcatg gtatcccaaa taaataaaat gtgccactac ccttgcacca
    15961 aaattatttt atgatgggta aagttagacc cttgagaggt ttttttttta aaaaaaaaaa
    16021 aaaaaaaaaa ctttcccaaa atgcctctct gtaaagccag gatcagaata taggtgtcct
    16081 aacttcctat ctaagagtta cgaatttctg actcagtctt tgagagaagg tgtttatcct
    16141 gaaccagaaa ctcaatgatg tatacctgtt taggtattaa atagttgtgt ttatatgccc
    16201 aaaaatttga ctttaggtat atgtgatatg ctttggttcc gatcaagcag gaggtcataa
    16261 gtttactcag aagtatccaa aatatgacat tcaagattta acttgcatat gtgtgtatat
    16321 gcatatattt atacatgtat atgtagattg aatgtgacat tatgtatttc taacataata
    16381 tttggcctgc cagcttataa atatgtattt aagcttttca ttgattgaca ttactgtaaa
    16441 aaatgaatta tgattgagaa gttctggata tttgctgttt ttttcatttt atattcttac
    16501 taaattattg aatttgttaa attaaaatgt gctatcactg tattgccaaa ttatggcaat
    16561 acactatgca gtattatttc aatactttaa gaggcatcta ttacttcatt gaacacataa
    16621 gcagctagcc tcctttcctc tgtaaataag gactttttgg catcctgatg ttcctcgctg
    16681 ttcatttggt atcatcctgg agttccatca agactgagga ttttctccat ggccaataaa
    16741 ctattgtcag catcagctca cgtttggctg tatgacaggg atatgtgaga agcccagaaa
    16801 taaatcacaa aaataataag gcatcttctg agtctctctg aagaagccag tgatccaaaa
    16861 actaacttca tatctgagtg agtcttggta ttcttgattt gcttgaagag gctgtgacat
    16921 attacaaggt gtgtaatttc ccaggcatat cacactgctt ctgtttcatg aattgatcaa
    16981 attgtccaga agtaaacatt tacaagattg agatttgaa
//
