LOCUS       XM_017004711            6760 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens anaphase promoting complex subunit 1
            (ANAPC1), transcript variant X3, mRNA.
ACCESSION   XM_017004711
VERSION     XM_017004711.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017004711.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6760
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..6760
                     /gene="ANAPC1"
                     /gene_synonym="APC1; MCPR; TSG24"
                     /note="anaphase promoting complex subunit 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 64 ESTs, 1911 long SRA reads, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 28 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:64682"
                     /db_xref="HGNC:HGNC:19988"
                     /db_xref="MIM:608473"
     CDS             277..6030
                     /gene="ANAPC1"
                     /gene_synonym="APC1; MCPR; TSG24"
                     /codon_start=1
                     /product="anaphase-promoting complex subunit 1 isoform X3"
                     /protein_id="XP_016860200.1"
                     /db_xref="GeneID:64682"
                     /db_xref="HGNC:HGNC:19988"
                     /db_xref="MIM:608473"
                     /translation="MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQP
                     ASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIW
                     SKGSKSQALAVYKAFTVDSPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCIN
                     MHSIEGKDYIASLPFQVANVWPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLD
                     EITPLVCKSGSLFGSSRVQYVVDHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKS
                     EEENVVLKFSEQGGTPQNVATSSSLTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSS
                     PSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNISSHNQSPKRHSISHSPNSNSN
                     GSFLAPETEPIVPELCIDHLWTETITNIREKNSQASKVFITSDLCGQKFLCFLVESQL
                     QLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTMLVLEGSGNLVLYTGVVRVGK
                     VFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSLDEVVLLSPVPELRDSSKL
                     HDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQA
                     IKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMMGYNTDRLAWTRNFD
                     FEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSLCLSPSEASQMKD
                     EDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELLVQLARDLK
                     LGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWVSSCLKGEG
                     MPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQVEQEENR
                     FSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDWPE
                     AVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNHEVMSLIWSE
                     DLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFT
                     LFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLK
                     IAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMT
                     SIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQ
                     GTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLN
                     VPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKT
                     NNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE
                     NSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKD
                     FMTYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNY
                     GFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLY
                     VLAAEPRLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKV
                     KGPRYWELLIDLSKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANR
                     NSEARAFKPETISAFTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETP
                     EMLPAYIAMDQAIRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNS
                     EFLPVVKCTIDNTLDQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHL
                     PPIGLEGLLKDLAGDSG"
     polyA_site      6760
                     /gene="ANAPC1"
                     /gene_synonym="APC1; MCPR; TSG24"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gcgaggcaag acgggaaagt caagatggac gcgtccattt gaacgtctcg cacgccttcc
       61 tgccattagc actcgagccc gctgctgttg cccgttcttc ctccagaata ggggagggag
      121 agggaatgag aagctgctgc ggcccaagag tcactgtgaa ggaccccgcc gctgccctcg
      181 ggcctcctcg gcccctgcgc ctccggggag cagccggggc tcgccgcgcc tgacgcgtcc
      241 cgagttatac agaaataatg ttgatatttg gaacccatgt cgaacttcta tgaagaaagg
      301 acaacgatga ttgcagcaag ggatttgcag gaatttgttc cttttggtcg agaccactgc
      361 aagcaccacc ctaatgcttt gaaccttcaa cttcgccagc tgcagccagc ttctgaatta
      421 tggtcttctg atggtgctgc tggcttggtg ggatcccttc aggaggttac aatccacgag
      481 aaacagaagg aaagctggca gttaaggaaa ggagtaagtg aaattggaga agatgtggac
      541 tatgatgagg aactctatgt tgctggaaat atggtgatat ggagcaaagg aagtaaaagc
      601 caggcattgg cagtttataa agcatttaca gttgacagtc ctgttcagca ggcattgtgg
      661 tgtgacttca ttatatcaca ggataagtct gaaaaggcct acagtagcaa tgaagtagaa
      721 aaatgcatat gtatattgca aagctcatgt attaacatgc atagcataga aggaaaggat
      781 tacatagctt cattaccatt tcaggttgca aatgtttggc ccactaaata tggattgctg
      841 tttgaacgaa gcgcttcttc acatgaagta cctccaggtt cacccagaga acctttacct
      901 actatgttca gcatgctgca cccactagat gaaataactc cacttgtttg taaatctgga
      961 agtctttttg gttcatcacg ggtgcaatat gttgtagatc atgcaatgaa aattgttttc
     1021 ctcaatactg acccctctat tgtaatgact tatgatgctg ttcaaaatgt gcattctgtg
     1081 tggactctcc ggagagtcaa atcagaggaa gagaatgttg ttttaaagtt ctctgaacag
     1141 gggggaaccc cacagaatgt ggccactagc agctccctca cagcacatct cagaagcctc
     1201 tccaaaggag attcccctgt gacttcacct ttccagaatt actcctccat tcacagccag
     1261 agtcgctcaa cctcatcacc cagtctacat tctcgctcac cttctatttc caacatggca
     1321 gctctaagtc gtgctcattc tcctgcgtta ggagtgcact ctttttcagg ggtgcaaagg
     1381 ttcaacattt caagccataa tcagtctcca aagagacata gtatttctca ttctccaaat
     1441 agtaattcta atggctcctt tcttgcacca gaaacggagc caattgttcc tgaactgtgt
     1501 attgaccatt tgtggacaga aacgattact aatataagag agaaaaattc acaagcctca
     1561 aaagtgttta ttacatctga cctatgtggg caaaagttcc tgtgcttttt agtagagtcc
     1621 cagctccagt tacgctgtgt aaagtttcaa gagagtaatg ataaaaccca gctcatcttt
     1681 ggttcagtga ccaacatacc agcaaaggat gcagcaccag tggagaaaat agacaccatg
     1741 ctggtcttgg aaggcagtgg aaacctggtg ctatacacag gagtggttcg ggtgggaaag
     1801 gtttttattc ctggactgcc agctccctct ctgacgatgt ccaacacaat gcctcggccc
     1861 agtactccac tagatggcgt tagtactcca aagcctctta gtaaactcct tggatcattg
     1921 gacgaggttg ttctgttgtc cccagttcca gaactgaggg attcttcaaa acttcatgat
     1981 tctctctata atgaggattg tactttccaa cagcttggaa cttacattca ttctatcaga
     2041 gatcctgtcc ataacagagt caccctggaa ctgagtaatg gctccatggt taggatcact
     2101 attcctgaaa ttgccacctc tgagttagta caaacgtgtt tgcaagcaat taagtttatc
     2161 ctgccaaaag aaatagcagt tcagatgctt gtcaagtggt acaatgtcca cagtgctcca
     2221 ggaggaccca gttatcactc agagtggaat ttatttgtga cttgtctcat gaacatgatg
     2281 ggttataaca cagaccgctt agcatggact agaaattttg actttgaagg atcactttct
     2341 cctgtcattg cgcccaaaaa agcaaggcct tccgagactg gatctgatga tgactgggaa
     2401 tatttactaa attcagacta ccaccagaat gttgagtctc atcttttgaa cagatcttta
     2461 tgtctgagtc cttcagaagc ttcacagatg aaggatgagg atttttcaca gaatctcagt
     2521 ctggattctt ctacacttct ctttactcac atacctgcaa tttttttcgt tcttcacctt
     2581 gtgtatgagg agcttaagtt gaatactcta atgggagaag gaatttgttc acttgttgaa
     2641 cttctcgttc agttggcaag ggacttaaaa ttggggcctt atgtagatca ttactataga
     2701 gactacccaa cgcttgtcag aactactgga caagtgtgca caattgatcc aggtcaaaca
     2761 ggatttatgc atcatccatc attttttacg tctgagccac caagtattta tcagtgggtg
     2821 agttcttgtc tgaagggtga aggaatgcca ccttatcctt acctccctgg aatctgtgaa
     2881 agaagcagac ttgtagtctt gagtattgca ctgtacatac ttggtgatga gagcttggtt
     2941 tctgatgaat cctcacagta tttaaccaga ataactatag ccccccagaa gttgcaagta
     3001 gaacaagagg aaaacaggtt tagtttcagg cattctacat ctgtttctag tctagctgaa
     3061 agattggttg tctggatgac taatgtagga ttcactttaa gagatttgga aactcttccc
     3121 tttggaattg ctcttcccat cagagatgca atttatcact gtcgtgagca gcctgcctca
     3181 gactggccag aagctgtctg tctcttgatt ggacgtcagg atctttccaa gcaggcctgc
     3241 gaaggaaact tacccaaagg gaagtctgtg ctctcatcag atgttccttc aggaacagaa
     3301 actgaggagg aagatgacgg catgaatgac atgaatcacg aggtcatgtc attaatatgg
     3361 agtgaagatt taagggtgca ggatgtgcga aggcttcttc agagtgcgca tcctgtccgt
     3421 gtcaacgtag tgcagtaccc agagctcagt gaccacgagt tcatcgagga aaaggaaaac
     3481 agattgctcc aattgtgtca gcgaactatg gctcttcctg taggacgagg aatgtttacc
     3541 ttgttttcgt accatcctgt tccaacagag ccattgccta ttcctaaatt gaatctgact
     3601 gggcgtgccc ctcctcggaa cacaacagta gaccttaata gtggaaacat cgatgtgcct
     3661 cccaacatga caagctgggc cagctttcat aatggtgtgg ctgctggcct gaagatagct
     3721 cctgcctccc agatcgactc agcttggatt gtttacaata agcccaagca tgctgagttg
     3781 gccaatgagt atgctggctt tctcatggct ctgggtttga atgggcacct taccaagctg
     3841 gcgactctca atatccatga ctacttgacc aagggccatg aaatgacaag cattggactg
     3901 ctacttggtg tttctgctgc aaaactaggc accatggata tgtctattac tcggcttctt
     3961 agcattcaca ttcctgctct cttaccccca acgtccacag agctggatgt tcctcacaat
     4021 gtccaagtgg ctgcagtggt tggcattggc cttgtatatc aagggacagc tcacagacat
     4081 actgcagaag tcctgttggc tgagatagga cggcctcctg gtcctgaaat ggaatactgc
     4141 actgacagag agtcatactc cttagctgct ggcttggccc tgggcatggt ctgcttgggg
     4201 catggcagca atttgatagg tatgtctgat ctcaatgtgc ctgagcagct ctatcagtac
     4261 atggttggag gacataggcg ctttcaaaca ggaatgcata gggagaaaca taaatcacca
     4321 agttatcaaa tcaaagaagg agataccata aatgtggatg tgacttgtcc aggtgctact
     4381 ctagctttgg ctatgatcta cttaaaaacc aataacagat ctattgcaga ttggctccga
     4441 gcccctgaca ccatgtattt gttggacttt gtgaagccag aatttctctt gcttaggaca
     4501 cttgctcgat gcctgatttt gtgggatgat attttaccaa attccaagtg ggttgacagc
     4561 aatgttcctc aaattataag agaaaatagt atctctctca gtgaaatcga attgccgtgc
     4621 tcagaggatt tgaatttgga aactttgtcc caagcacatg tctacataat tgcaggagcc
     4681 tgcttgtctc tgggttttcg atttgctggc tcagaaaact tatcagcatt taactgtttg
     4741 cataaatttg ccaaagattt tatgacttat ttgtccgcac ctaatgcttc tgttacaggt
     4801 cctcataacc tagaaacttg tctgagcgtg gtgctgctgt ctctcgccat ggtcatggct
     4861 ggctcaggaa acctaaaggt tttgcagctt tgtcgcttct tacacatgaa aacgggtggt
     4921 gaaatgaact atggttttca cttagcccac cacatggccc ttggacttct atttttggga
     4981 ggaggaaggt actctttgag cacatcaaat tcttccattg ccgctcttct ctgtgccctt
     5041 tatccgcact tcccagctca cagcactgac aaccggtatc atctccaggc tctccggcac
     5101 ctctatgtgc tggccgcgga gcccaggctt ctagtgcctg tggatgtgga cacaaacacg
     5161 ccctgctatg ccctcttaga agttacctac aagggcactc agtggtatga acaaaccaaa
     5221 gaagaattga tggctcctac ccttcttcca gaactccatc ttttaaagca gattaaagta
     5281 aaaggcccaa gatactggga actgctcata gatttaagca aaggaacaca acacttgaag
     5341 tccatccttt ccaaggatgg ggttttatat gttaaactcc gggcgggtca gctctcctac
     5401 aaagaagatc caatgggatg gcaaagtttg ttggctcaga ctgttgctaa caggaactct
     5461 gaagcccggg ctttcaagcc agaaacaatc tcagcattca cttctgatcc agcacttctg
     5521 tcatttgctg aatatttctg caagccaact gtgaacatgg gtcagaaaca ggaaattctg
     5581 gatctctttt cttcagtact ctatgaatgt gttacccagg agaccccaga gatgttgcct
     5641 gcatacatcg caatggatca ggctataaga agacttggga gaagagaaat gtctgagact
     5701 tctgaacttt ggcagataaa gttggtgtta gagtttttca gctcccgaag ccatcaggag
     5761 cggctgcaga accaccctaa gcgggggctc tttatgaact cggaattcct ccctgttgtg
     5821 aagtgcacca ttgataatac cctggaccag tggctacaag tcgggggtga tatgtgtgtg
     5881 cacgcctacc tcagcgggca gcccttggag gaatcacagc tgagcatgct ggcctgcttc
     5941 ctcgtctacc actctgtgcc agctccacag cacctgccac ctataggact agaaggtctt
     6001 ctgaaggacc tagcaggaga ctcaggttga aaccctacag aacctcgccg tgtgccgccc
     6061 agtcttcctt gaataaggcc attttctcac cctttgtcta gtaactagct gactccacag
     6121 ctcatggtaa ggggcatgtc tcagctcagg gggtctcctg acatcccaga ggaagcaata
     6181 aggtgggggt ctttcatctc tcagcctgat gatctgtgca cacccacttg atgggaggcc
     6241 agggtgcctg tgggcagatg ggtcagagtg tgggccagga tttggagtag aagccagagc
     6301 atgtgaaaat ccaaaccagg aagacttcgt tgcctcccgc atgtggggtt gaaggcctct
     6361 cttctgtggt ctcccatcct catgctgatc aaattggggg ggaatgtctc actgtgtgag
     6421 gatcacccca attaagctgt gggggaggac acagaatctg atcccctctg tatccttagc
     6481 gcatgctacc tccagccacc aggggaaaga agcagaggtg aggtgggaga ggtggccact
     6541 ctggacggtg taactgggct ggctgcctct cagcgcccac gagcacccca cagatatcca
     6601 cgctagtgta caaaggttcc caagtggtgg ccttttcctg cttccaaggg ctgcccgggt
     6661 tcccccctct ctgaaataga ttggttgctt ctcattacgt cacaagctgc agaaaaaaaa
     6721 tttaaataaa aagcctctac agctgtgtcc ttaactctta
//
