LOCUS       XM_047428406            7376 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens aldehyde dehydrogenase 1 family member L2
            (ALDH1L2), transcript variant X1, mRNA.
ACCESSION   XM_047428406
VERSION     XM_047428406.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000012.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7376
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
     gene            1..7376
                     /gene="ALDH1L2"
                     /gene_synonym="mtFDH"
                     /note="aldehyde dehydrogenase 1 family member L2; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 4 mRNAs, 14 ESTs, 308 long SRA reads, 3 Proteins, and
                     98% coverage of the annotated genomic feature by RNAseq
                     alignments, including 7 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:160428"
                     /db_xref="HGNC:HGNC:26777"
                     /db_xref="MIM:613584"
     CDS             310..2742
                     /gene="ALDH1L2"
                     /gene_synonym="mtFDH"
                     /codon_start=1
                     /product="mitochondrial 10-formyltetrahydrofolate
                     dehydrogenase isoform X1"
                     /protein_id="XP_047284362.1"
                     /db_xref="GeneID:160428"
                     /db_xref="HGNC:HGNC:26777"
                     /db_xref="MIM:613584"
                     /translation="MDIIDSPKHGSIIYHPSILPRHRGASAINWTLIMGDKKAGFSVF
                     WADDGLDTGPILLQRSCDVEPNDTVDALYNRFLFPEGIKAMVEAVQLIADGKAPRIPQ
                     PEEGATYEGIQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEINGQMVTFYGSTLLN
                     SSVPPGEPLEIKGAKKPGLVTKNGLVLFGNDGKALTVRNLQFEDGKMIPASQYFSTGE
                     TSVVELTAEEVKVAETIKVIWAGILSNVPIIEDSTDFFKSGASSMDVARLVEEIRQKC
                     GGLQLQNEDVYMATKFEGFIQKVVRKLRGEDQEVELVVDYISKEVNEIMVKMPYQCFI
                     NGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFENGEWGRMNARE
                     RGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQG
                     STIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQ
                     VTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQI
                     MKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVE
                     ESIHDEFVTRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVY
                     GGRQVQRPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEY
                     GLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGEEALN
                     EYLKTKTVTLEY"
ORIGIN      
        1 gagtagctgg gattacaggt ttatttcaaa aacaagctga agttggcact aattggccag
       61 agcctctttg gacaagaagt ctatagccac ctccgcaaag agggccaccg agtagtaggg
      121 gtgttcacag ttccagacaa ggatggaaaa gctgaccctc tggctttggc tgcagagaaa
      181 gatgggaccc ctgtgttcaa gcttcctaaa tggagggtca agggcaagac catcaaagaa
      241 gtggcagaag cctacagatc cgtgggtgca gagctaaatg tgctcccttt ctgcactcag
      301 ttcattccca tggatataat tgatagtcca aagcacggct ctatcattta tcacccatcc
      361 atcctgccca ggcacagagg agcctctgct atcaattgga ctctaattat gggagataag
      421 aaagctgggt tttctgtttt ctgggctgat gatggcttgg atacaggacc catccttctt
      481 cagagatcat gtgatgttga acccaatgat acagtggatg cactttataa tcggtttctt
      541 tttcctgaag gaatcaaggc catggtagaa gctgtccaac tcatagctga tggaaaagct
      601 cctcgtatac cccagccaga agaaggggca acatatgaag gtatccagaa aaaggaaaat
      661 gctgagattt cttgggacca gtctgccgaa gttttacata actggattcg aggtcatgat
      721 aaagtccctg gagcttggac agagataaat ggacagatgg tcactttcta tggctcgaca
      781 ttactgaata gctctgtgcc tcctggagaa ccactggaaa ttaaaggtgc caagaagcct
      841 ggtctcgtta ccaaaaatgg acttgttctt tttggtaacg atggaaaagc actgacggtg
      901 agaaatctgc agtttgaaga tggaaaaatg atccctgcct ctcagtactt ttcaacgggt
      961 gagacgtcag tggtagaact gacagctgaa gaggtgaaag tggcagagac catcaaggtc
     1021 atctgggctg gaattttaag caatgtcccc attattgaag actcaacaga cttctttaaa
     1081 tctggagcaa gctcaatgga tgttgccagg ctggttgaag agatcagaca gaaatgtggt
     1141 gggcttcagt tgcagaatga agatgtctat atggccacca agtttgaagg ctttatccaa
     1201 aaggtcgtga ggaaactgag aggagaagat caagaggtgg agctggttgt agattatatt
     1261 tcaaaggagg tcaatgaaat catggtaaaa atgccatacc agtgtttcat aaatggacag
     1321 ttcacagatg cagacgatgg aaagacttac gacactatca acccaacaga tggatctaca
     1381 atatgcaaag tatcctacgc ttctttggcg gatgttgata aagcagtagc agcagcaaaa
     1441 gatgcttttg aaaacggtga atggggaaga atgaatgcaa gagaaagagg aagattgatg
     1501 tatagacttg cagacctact ggaagagaac caagaagagc tggcaactat tgaagccctt
     1561 gattcagggg ctgtctatac cttggccctg aagacacaca ttggaatgtc tgtgcaaaca
     1621 ttcagatatt ttgctggctg gtgcgacaaa attcagggtt ctactattcc aatcaaccag
     1681 gcccgtccaa atcgcaatct gaccttcacc aagaaagagc cactcggtgt ctgtgccatt
     1741 attattccct ggaactaccc gctgatgatg ctggcatgga agagtgctgc gtgtttggca
     1801 gcaggcaata ccttagtgct caagccagca caggtcacgc ccttgactgc tttgaagttt
     1861 gcagaactgt ctgtgaaagc aggctttcca aagggggtca tcaacatcat tccaggctca
     1921 ggtggcatag caggacaacg tctgtctgaa catcctgaca tccgcaaact tggtttcact
     1981 ggatccactc ctattggcaa acagatcatg aagagctgtg ctgttagcaa cttgaagaaa
     2041 gtttcccttg agcttggtgg caagtctcca cttataatat ttaatgactg tgaacttgac
     2101 aaggctgtgc gaatgggcat gggagcagta tttttcaaca aaggagagaa ctgtattgct
     2161 gctgggcggt tgttcgtgga agaatccatc cacgacgaat ttgtgacaag agtggtagaa
     2221 gaaattaaaa agatgaaaat tggtgatcca cttgacagat ccactgatca tgggccccaa
     2281 aatcataagg ctcatctgga aaagctgctg caatactgtg aaactggagt gaaagaaggg
     2341 gccactttgg tgtacggggg aagacaagtc caaaggccag gctttttcat ggagccgacc
     2401 gtgttcacag atgtggaaga ctacatgtac ctcgccaaag aggaatcctt tgggcctatt
     2461 atggtcattt ctaaattcca aaatggggac atcgatggag tgttgcagcg agcaaatagt
     2521 acagagtatg gtttggcctc aggggttttt acaagagaca taaacaaagc tatgtatgtg
     2581 agtgaaaaac tggaagcagg aactgttttt attaacacat acaacaagac agatgtggcg
     2641 gccccatttg gcggagttaa acaatctggc tttggaaaag acttaggtga ggaagctcta
     2701 aatgaatatc tcaaaaccaa gacggtgaca ctggaatatt agagcaacac catcatcagg
     2761 aaagccttga cagacagccc tttacaactc tggacacact taagaagatt gggtgtgttg
     2821 aggcaggagg tgtcagccac aaaccaaaaa atacacagat ggaccatgaa gagggccagg
     2881 ccatgttaaa gcatttacac atgtgcctga gtattttcta atacaccttc cagtgatttg
     2941 gagttgttgc attttgacta tgttgtatat catacgtatt tctaaaatac caagctgttt
     3001 ctcccctacc tagacaaatc tattcatggt tcccatcttg aagatgtcag taccatgcag
     3061 ttataataca caaggtgcat ttattggaaa ctttgtataa tatgtacagg tttttaacct
     3121 ctgaactata catagggggt tattaaaaag attttctata agtcttctaa ggaacagtat
     3181 aacctgtaag gaatgtgaag gtagttcttt tttagtattt ggaaataaga tacatctttg
     3241 tgcctttgat attccatttt ttaacccact gtgatgggtg atcaacctag aaacattatc
     3301 ttgagtacct actaggtacc aggtactata ttatgttctg aggagtatag agaatttaat
     3361 gatatgatgg ctggccccca catagtttaa attttagtaa atagcttttg aagcaaattt
     3421 tacatatgat atagtagaag gctgatcctg gtcgtatcat accatcttcc tatctatgta
     3481 actttgggaa actctcgcaa ctcctctgag cctctgcttc cctatgtgta aaacagggat
     3541 agtaaatgcc ttcctcagga cccttaatag gagaattcat tgcagtaatg taagtaaagc
     3601 acctcacatt aatgctttgc tcatggtaag tactcaaatt taactctgat ttcctccgtc
     3661 accattctta aaagatattg agatagttta attaactaga tgaattcatt tcccacaacc
     3721 cttttcaatc atcaattcct agatattttt ctcatccatt gttctgacac aatgcctgat
     3781 acagcagcac tgaaaaatgc cacacaatga aaaatggcaa tagtacaagg aaaaggggtg
     3841 cttttctttg ggcagctcgc tcgtccttca tgggacatct tactttccat ttttctacct
     3901 attggttctg ctgttcactg gctgtgtgat cttgggcaag atagtaatct aatatctcag
     3961 agcctaggtt gagtatctat aaaatgaaaa tcaaatctct atctcagtag gtgttgcaag
     4021 gattcagtga gataatatac ataatgcact taacaaggcg tttggaccat agcattgaag
     4081 aaatggaaac tattaacagc ccatttccca ttggcagaca gaagtagtca ggtgagtaaa
     4141 ttttcaccat ctatgtgtga ctagaaggcg gcaaatttct gaatcacatg agtctccaaa
     4201 agatagccag aaagttaaat tctattaatc ctcctttaaa aataaaattt cagtaaacat
     4261 tcctttttct ttggctttga agaagcctta gggaatattt gtcattttgg agacttggca
     4321 gaataacatg aggggattgt agggaatcaa taaaaactaa acaacaaaat cagagtcaga
     4381 gaacattttc aaaaggaaga ataggaggtt tgatcccagc atgataaaca gagcgaattt
     4441 ggcctggaag cacttttgat tatactatag ctcatttacc atcccagagt ttggcacagc
     4501 tgaaatttta agttggaatg aatattcact gggcccaaaa tgacagttca tatttgaata
     4561 aaagtgacaa aagccttttt ataagtaatc acttttaagt gaaatgtttt aactgatttc
     4621 atgtgattta gaatatgatt taatcaaatt attttaatga tagatggaat ggcagacaaa
     4681 aacatgcctg tccttctaga ctgattttac tttaccctct aatattcatc tcagtagcag
     4741 tgttttaaat attctctggg ctgcaaaact ctttgggaat ctgataaaag ctatgaacac
     4801 tccctgtgtc ccgcttctac ccccaaaatt catgtgcaca cacacaattc tgcaagtatc
     4861 ttcaaagggt tcacagacct cccaaaggcc atgcttgggc cccagattaa gaactccttt
     4921 ctccatagca agttttaaac atttcttacc agcttacatt tttagatctg gctgatcaga
     4981 atcaaaggct ctgtgtaata cataaagtta ccaagtgaac tggaattgga acatcaccct
     5041 ccccagcctg ctaggtgatt tacttaacac atagagtaat aaaatcatcg ctgttgcttt
     5101 agatcacgga ttattttgct aataatgcta aggatgaagc tgtgatctta ttatcacctg
     5161 aatcgggagg tgtggacact ttaagcagtt ccactttcct tctaattccc catccccatg
     5221 cctttgctaa agctgtccct tttgctctaa cacccttcct ggaccttcct accctagctg
     5281 ggctaagtgt ttctcctcag cgttcccact tgtttcaaac atagcactta ccacttgtac
     5341 taaaattact tgccttctta attagatatg aacaaccctc cccaactcca gtatgggcct
     5401 tctgtcaata ataatacgat atgacagcta ccatttatta agggcctcct gtatgaaaga
     5461 ccttaggcta agcatgtttt aaatgttatt taatcttcac aatctctgaa aaaaatgaag
     5521 aaatcaacgt gcttttctta ctacctctac ccctaagcca ttattacttt tttttttttt
     5581 tgagacagag ttttgctctt gttgcccagg ctgcagtgca gtggtgcaat cttggctcac
     5641 tgcaacctct gcctcttggg ttcaagcgat tgtcatgcct tagccttcca agtagctggg
     5701 attacaggtg tgtgccacta cacctggcta agtagagatg gggtttcgcc atgttggcca
     5761 ggctggtctt gaactcctga cctcaagtga tccacctgcc tccgcctccc aaagtgctgg
     5821 gattacaggc atgaaccact gcacctggcc tgttacctct ttcctacaat tttgctcaag
     5881 tctcccaact ggtcttctgg attcctctct tctgcggtcc tgttcaaagc ttaagtcaga
     5941 cagtgtcact tcactcgtct gtttaaaacc tttcaatggc ccccatttca cgtagaccaa
     6001 agtccaacgt atttacctgg cctactgatc ttgctcctag ctacctctga cctcatctcc
     6061 tgtcaatttc cctctcattc tgttccacca tcctgactgc cttgacttcc tcaacagaac
     6121 aagcctgctc ctgcctcagg gcctctgtcc ttattcttcc tcttcccagg ggtgtgctgg
     6181 taaaatattt aacaaatagt tctccgggac gggggagaaa accctcattt gtagcatttg
     6241 caggtatcta tgtgtaaata ctctcatcaa ggctattttt gagccactaa tttgccttca
     6301 ctgaatacag agtttgggaa gagatgcatg ccatcagaac aaatgcaagc cagcaccagc
     6361 acaccactgc ctcttcctgc aactcttgtc catacacaac ctcatggctg gctggctcac
     6421 ttcctgcagg tctctcctca aatatcatct gatgagagac acattccctg actatgcttt
     6481 ctaaaatagg ccatatgccc ccacattcat accccatctg ctgtcattct ttattctttt
     6541 tataagtgca ttattttcat agcacttatc actacctgtt gtatattaat caatgatctt
     6601 ttcccattag aatgtaagtt tcatgaacag gtacttgttt taatactgta tctccagtcc
     6661 taatgtgtaa caggagccca ataaatgttt gctttcaaat ggagaggtta agtaacctgc
     6721 tcaaatcaca cagctattaa gtggcagaac aggttttcaa gcaatgcatc tggtggtttt
     6781 aactaagtcg agatagtttt tattcctaat gcctaaatca gggcctaggt agtgagctgt
     6841 gggcacatat taagtattgg ttaaactaaa aataataagc aaaatggaca ttatctataa
     6901 aagcttttgt ggaaatggct agagctaggg taaggaaaca aatttggttc cccatacctg
     6961 ccctccaaga aaataaagct gtcaaggaaa atctgggcta agagtaggat atgagggatg
     7021 atggataagg catgagacat gagaaataag ggggattaaa ttattattac tattatacaa
     7081 atgatgcctg agtagatttt taaaatgatt aaatacccaa tgatgtaaaa aacatttata
     7141 aaataggaaa gtaagactga ctcaaccata atttgttgag tcaacccaaa aatctatttg
     7201 gttattttca aacagaaata gcctacagat gatatctgag attgttccaa actttttcta
     7261 tgaatatgta tacttttttt acataattaa cataatactg tatattaatt tgttacctgc
     7321 tttttcaatt aacaatatat cataagcatc tatgccaata aacacaattc tgcata
//
