LOCUS       NM_001626               5250 bp    mRNA    linear   PRI 11-FEB-2025
DEFINITION  Homo sapiens AKT serine/threonine kinase 2 (AKT2), transcript
            variant 1, mRNA.
ACCESSION   NM_001626
VERSION     NM_001626.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5250)
  AUTHORS   Zhao,C., Zhang,F., Tian,Y., Tang,B., Luo,J. and Zhang,J.
  TITLE     m 6 A reader IGF2BP1 reduces the sensitivity of nasopharyngeal
            carcinoma cells to Taxol by upregulation of AKT2
  JOURNAL   Anticancer Drugs 35 (6), 501-511 (2024)
   PUBMED   38478015
  REMARK    GeneRIF: m 6 A reader IGF2BP1 reduces the sensitivity of
            nasopharyngeal carcinoma cells to Taxol by upregulation of AKT2.
REFERENCE   2  (bases 1 to 5250)
  AUTHORS   Huang,F., Zhao,N., Cai,P., Hou,M., Yang,S., Zheng,B., Ma,Q.,
            Jiang,J., Gai,X., Mao,Y., Wang,L., Hu,Z., Zha,X., Liu,F. and
            Zhang,H.
  TITLE     Active AKT2 stimulation of SREBP1/SCD1-mediated lipid metabolism
            boosts hepatosteatosis and cancer
  JOURNAL   Transl Res 268, 51-62 (2024)
   PUBMED   38244769
  REMARK    GeneRIF: Active AKT2 stimulation of SREBP1/SCD1-mediated lipid
            metabolism boosts hepatosteatosis and cancer.
REFERENCE   3  (bases 1 to 5250)
  AUTHORS   Corre,E., Soum,C., Pfeifer,R., Bessiere,C., Dailhau,S.,
            Marboeuf,C., Meggetto,F., Touriol,C., Recher,C., Bousquet,M. and
            Pyronnet,S.
  TITLE     Differential prognostic values of the three AKT isoforms in acute
            myeloid leukemia
  JOURNAL   Sci Rep 14 (1), 7070 (2024)
   PUBMED   38528080
  REMARK    GeneRIF: Differential prognostic values of the three AKT isoforms
            in acute myeloid leukemia.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5250)
  AUTHORS   Tian,L.Y., Smit,D.J., Popova,N.V., Horn,S., Velasquez,L.N.,
            Huber,S. and Jucker,M.
  TITLE     All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate
            Production in Human Hepatocellular Carcinoma Cell Lines
  JOURNAL   Int J Mol Sci 25 (4), 2168 (2024)
   PUBMED   38396845
  REMARK    GeneRIF: All Three AKT Isoforms Can Upregulate Oxygen Metabolism
            and Lactate Production in Human Hepatocellular Carcinoma Cell
            Lines.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5250)
  AUTHORS   Roberts,B.M., Geddis,A.V. and Matheny,R.W. Jr.
  TITLE     Differential activation of AKT isoforms by growth factors in human
            myotubes
  JOURNAL   Physiol Rep 11 (20), e15805 (2023)
   PUBMED   37879895
  REMARK    GeneRIF: Differential activation of AKT isoforms by growth factors
            in human myotubes.
REFERENCE   6  (bases 1 to 5250)
  AUTHORS   Meier,R., Alessi,D.R., Cron,P., Andjelkovic,M. and Hemmings,B.A.
  TITLE     Mitogenic activation, phosphorylation, and nuclear translocation of
            protein kinase Bbeta
  JOURNAL   J Biol Chem 272 (48), 30491-30497 (1997)
   PUBMED   9374542
REFERENCE   7  (bases 1 to 5250)
  AUTHORS   Cheng,J.Q., Ruggeri,B., Klein,W.M., Sonoda,G., Altomare,D.A.,
            Watson,D.K. and Testa,J.R.
  TITLE     Amplification of AKT2 in human pancreatic cells and inhibition of
            AKT2 expression and tumorigenicity by antisense RNA
  JOURNAL   Proc Natl Acad Sci U S A 93 (8), 3636-3641 (1996)
   PUBMED   8622988
REFERENCE   8  (bases 1 to 5250)
  AUTHORS   Cheng,J.Q., Godwin,A.K., Bellacosa,A., Taguchi,T., Franke,T.F.,
            Hamilton,T.C., Tsichlis,P.N. and Testa,J.R.
  TITLE     AKT2, a putative oncogene encoding a member of a subfamily of
            protein-serine/threonine kinases, is amplified in human ovarian
            carcinomas
  JOURNAL   Proc Natl Acad Sci U S A 89 (19), 9267-9271 (1992)
   PUBMED   1409633
REFERENCE   9  (bases 1 to 5250)
  AUTHORS   Jones,P.F., Jakubowicz,T. and Hemmings,B.A.
  TITLE     Molecular cloning of a second form of rac protein kinase
  JOURNAL   Cell Regul 2 (12), 1001-1009 (1991)
   PUBMED   1801921
REFERENCE   10 (bases 1 to 5250)
  AUTHORS   Staal,S.P.
  TITLE     Molecular cloning of the akt oncogene and its human homologues AKT1
            and AKT2: amplification of AKT1 in a primary human gastric
            adenocarcinoma
  JOURNAL   Proc Natl Acad Sci U S A 84 (14), 5034-5037 (1987)
   PUBMED   3037531
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC040028.1, BC120994.1,
            AK122839.1, AC118344.2, KC877734.1 and BM675176.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_001626.5.
            
            Summary: This gene is a putative oncogene encoding a protein
            belonging to a subfamily of serine/threonine kinases containing
            SH2-like (Src homology 2-like) domains, which is involved in
            signaling pathways. The gene serves as an oncogene in the
            tumorigenesis of cancer cells For example, its overexpression
            contributes to the malignant phenotype of a subset of human ductal
            pancreatic cancers. The encoded protein is a general protein kinase
            capable of phophorylating several known proteins, and has also been
            implicated in insulin signaling. [provided by RefSeq, Nov 2019].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KU159425.1, SRR14038193.2710856.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000392038.7/ ENSP00000375892.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1282              BC040028.1         16-1297
            1283-1728           BC120994.1         1079-1524
            1729-3232           AK122839.1         2950-4453
            3233-3970           AC118344.2         136121-136858
            3971-4351           KC877734.1         1-381
            4352-5243           AC118344.2         137240-138131
            5244-5250           BM675176.1         18-24               c
FEATURES             Location/Qualifiers
     source          1..5250
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.2"
     gene            1..5250
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /note="AKT serine/threonine kinase 2"
                     /db_xref="GeneID:208"
                     /db_xref="HGNC:HGNC:392"
                     /db_xref="MIM:164731"
     exon            1..165
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /inference="alignment:Splign:2.1.0"
     exon            166..295
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /inference="alignment:Splign:2.1.0"
     CDS             250..1695
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /EC_number="2.7.11.1"
                     /note="isoform 1 is encoded by transcript variant 1; rac
                     protein kinase beta; v-akt murine thymoma viral oncogene
                     homolog 2; RAC-PK-beta; RAC-beta serine/threonine-protein
                     kinase; murine thymoma viral (v-akt) homolog-2; PKB beta;
                     protein kinase Akt-2; putative v-akt murine thymoma viral
                     oncoprotein 2; protein kinase B beta"
                     /codon_start=1
                     /product="RAC-beta serine/threonine-protein kinase isoform
                     1"
                     /protein_id="NP_001617.1"
                     /db_xref="CCDS:CCDS12552.1"
                     /db_xref="GeneID:208"
                     /db_xref="HGNC:HGNC:392"
                     /db_xref="MIM:164731"
                     /translation="MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEA
                     PDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRA
                     IQMVANSLKQRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGK
                     GTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYA
                     FQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDI
                     KLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWW
                     GLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQR
                     LGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITI
                     TPPDRYDSLGLLELDQRTHFPQFSYSASIRE"
     exon            296..424
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /inference="alignment:Splign:2.1.0"
     exon            425..536
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /inference="alignment:Splign:2.1.0"
     exon            537..690
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /inference="alignment:Splign:2.1.0"
     exon            691..822
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /inference="alignment:Splign:2.1.0"
     exon            823..888
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /inference="alignment:Splign:2.1.0"
     exon            889..957
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1080
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1209
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /inference="alignment:Splign:2.1.0"
     exon            1210..1424
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /inference="alignment:Splign:2.1.0"
     exon            1425..1512
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..1615
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..5250
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3213..3218
                     /regulatory_class="polyA_signal_sequence"
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /note="hexamer: AATAAA"
     polyA_site      3238
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /note="major polyA site"
     regulatory      4447..4452
                     /regulatory_class="polyA_signal_sequence"
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /note="hexamer: AATAAA"
     polyA_site      4467
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
     regulatory      5228..5233
                     /regulatory_class="polyA_signal_sequence"
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
                     /note="hexamer: AATAAA"
     polyA_site      5250
                     /gene="AKT2"
                     /gene_synonym="HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA"
ORIGIN      
        1 gccgtgctag ccgttgggcc tgcctcggag gaggcgtcgc cgccgccgct gccgctgccg
       61 gcgccgttgc cgctgccggg aaacacaagg aaagggaacc agcgcagcgt ggcgatgggc
      121 gggggtagag ccccgccgga gaggctgggc ggctgccggt gacagactgt gccctgtcca
      181 cggtgcctcc tgcatgtcct gctgccctga gctgtcccga gctaggtgac agcgtaccac
      241 gctgccacca tgaatgaggt gtctgtcatc aaagaaggct ggctccacaa gcgtggtgaa
      301 tacatcaaga cctggaggcc acggtacttc ctgctgaaga gcgacggctc cttcattggg
      361 tacaaggaga ggcccgaggc ccctgatcag actctacccc ccttaaacaa cttctccgta
      421 gcagaatgcc agctgatgaa gaccgagagg ccgcgaccca acacctttgt catacgctgc
      481 ctgcagtgga ccacagtcat cgagaggacc ttccacgtgg attctccaga cgagagggag
      541 gagtggatgc gggccatcca gatggtcgcc aacagcctca agcagcgggc cccaggcgag
      601 gaccccatgg actacaagtg tggctccccc agtgactcct ccacgactga ggagatggaa
      661 gtggcggtca gcaaggcacg ggctaaagtg accatgaatg acttcgacta tctcaaactc
      721 cttggcaagg gaacctttgg caaagtcatc ctggtgcggg agaaggccac tggccgctac
      781 tacgccatga agatcctgcg gaaggaagtc atcattgcca aggatgaagt cgctcacaca
      841 gtcaccgaga gccgggtcct ccagaacacc aggcacccgt tcctcactgc gctgaagtat
      901 gccttccaga cccacgaccg cctgtgcttt gtgatggagt atgccaacgg gggtgagctg
      961 ttcttccacc tgtcccggga gcgtgtcttc acagaggagc gggcccggtt ttatggtgca
     1021 gagattgtct cggctcttga gtacttgcac tcgcgggacg tggtataccg cgacatcaag
     1081 ctggaaaacc tcatgctgga caaagatggc cacatcaaga tcactgactt tggcctctgc
     1141 aaagagggca tcagtgacgg ggccaccatg aaaaccttct gtgggacccc ggagtacctg
     1201 gcgcctgagg tgctggagga caatgactat ggccgggccg tggactggtg ggggctgggt
     1261 gtggtcatgt acgagatgat gtgcggccgc ctgcccttct acaaccagga ccacgagcgc
     1321 ctcttcgagc tcatcctcat ggaagagatc cgcttcccgc gcacgctcag ccccgaggcc
     1381 aagtccctgc ttgctgggct gcttaagaag gaccccaagc agaggcttgg tggggggccc
     1441 agcgatgcca aggaggtcat ggagcacagg ttcttcctca gcatcaactg gcaggacgtg
     1501 gtccagaaga agctcctgcc acccttcaaa cctcaggtca cgtccgaggt cgacacaagg
     1561 tacttcgatg atgaatttac cgcccagtcc atcacaatca caccccctga ccgctatgac
     1621 agcctgggct tactggagct ggaccagcgg acccacttcc cccagttctc ctactcggcc
     1681 agcatccgcg agtgagcagt ctgcccacgc agaggacgca cgctcgctgc catcaccgct
     1741 gggtggtttt ttccccctaa ctttttactt agcctttttg gtttgtgtcc ccacccccac
     1801 ctcctcaccc cctttccagt tcttcttcag gcccctccca gacgcacccc agcggcccct
     1861 gcagcccctg cctccagcct ccagcctcac ctttgtgccc agactcgcat ttggaagact
     1921 ccacctcccg cccaggcctg ggctgttggg cggttggaga ttcaggtttt aatccacaca
     1981 agccccagtg aggggtgaag catggcgcct ggggcctgcc tgagtttctg gcctgggtgt
     2041 cgtgctggtg tctgcctccg cgctgctgca tctggacgaa ggctgccttc tggtgggacg
     2101 cgacacccgg cagacagtgg tgctgccttc caggccccgt ggcctaggct cggagtggcc
     2161 aggcacgggg cggtccaatc ccccacccgc tgtcccccta tgggggcaga aaagcaataa
     2221 tgtccagggg caggcagggg cccttgggag ctgcagggct gggggttagg gctgctccct
     2281 ggtgaatgga gtcagatcct aggatctgta ccatggggaa ccaggagtgg ccgggctggg
     2341 tgccgcctcc tggtccggcc tcctccccac caaactgtcc tcaccctatg gatgaggcag
     2401 gaggaacatt tggggccaaa cctgcctgcc tcccagcccc gtgccttact agggcttcct
     2461 tccagctggc cttacctccc gctggaccct gggcctggcc tggccccact gggggctatg
     2521 ggctgggctc accctctcct ctgcgggggt ggagggccac cagccttggc tgttacaatc
     2581 ttacaccgga cagtattggg ccccatggac ttggtcaggg aggggtgggg gtgggcatct
     2641 ctggtaccta ttggggtggg gggcctctga aaagggaggc tcctaggccc ccctcacccc
     2701 tccctctccc cagggcccca cgttctgcag ccttaaggtt gaacatgagt gcacgtccat
     2761 gtcagtgctg tgggactcct gtgcgtgcct cggactgcgt gtgtcggcgg gacgcaggca
     2821 cacgtgggtg tgtgtgcatg tgtgtttgtg tgagggcagc gtgtcctcca gtgtgcatgg
     2881 tgtgtgggct tgggccccat ccctggcccg agcatttcat cctgtggggg aggggtgctg
     2941 acctagtggg aggagcccca ctgtgatcca tgagctgccc tgcccacgcc tcccctccct
     3001 gtagcaacac ctctgggtgt ttggagttta gcttttgtgg gtttgctctc cctatcccat
     3061 ctcctgtact acacagttca tggcagggtg gggaggggtg gggttggttc gggtgggtga
     3121 gggtcttttt cctctgtgtg cgatgttgtt atctgacagt tctccgtccc tactggcctt
     3181 tctcctcgtc ttcatatttg tacggtacaa gcaataaaga cactcatttc agaccagggc
     3241 ccagcctgca ctcacgccag cccaaccact ctgggctttg ccttggtgat ggagtcagac
     3301 ccctgggccc cagctcctcc tgtactagcc gttcccttca gcaaggaggg cactgagctc
     3361 agggtgaggg cagctggggt gtgtgcagga gctcaggctg gagagggtgg gtggagctgg
     3421 tgctgtgggg ctgaggggta tgggaaggct ccccgcatgt gggggtgggg tggacagaga
     3481 ccactccagg ccctcagtgc tgcttaggct aagagaggtg gggtggaggg acagggctgg
     3541 aagatctggg tagcccagaa tgaggagggt gcctgtgctg tcactgaatg agagggagtg
     3601 gttcattcca cccggctgcc gagcctcaga ggggggcatt cctatcctgc cccacctccc
     3661 tgtttatgct gccacctgga agccttgagg cccccaaatt ccagtacaga cccagtggtg
     3721 tgttcatggt ggcgtggttg ctgtcacctg ggagctcctg agcgtttggt tagaaccctg
     3781 ttcagcttgg ggtcagccct cccctagtca ctgcccttta gcctggatgt gtctgggccc
     3841 ctgcacttcc cgtgcttgag tcacgtggct gcatggccgg gcgctggccg gatggaacac
     3901 ctcccccagc aagggaccag ggaccagagc cctggcctgc cctgctgagc cctgctgtgc
     3961 agagggcctg gcacagatga atttgagatt ttgccgcaag gtgttagcac ttcacaccca
     4021 ttgagtcttt gagattttaa gtgaatgtaa gcagaaaaag tcagatccaa tttacagaaa
     4081 tcagagttag ctacagctag gactcgtttg gttggggttt tttagtttgt ctttctaaag
     4141 tcatgtggac cttaatttaa ttacaaaagt ctaccctggt ggtcataaaa taggcaggcc
     4201 tatgaagaaa ggccttttac tcttccatct cgtcccagcc ccgagttgac ccacgttgct
     4261 gctcctcaca ccatggtgat gcaggtctcg tagtgtgggc acaggcctgg ctacctcatc
     4321 tttttagtgc ctctctcctc ttccacagga tggggtccca cagctgcagc agctggcccc
     4381 gtagttgagc atgtgtggtt atcctgtaga gcttttccca agaagggtgt ttgaacttag
     4441 agtcttaata aaatcttacc aaataaattt tgagtagaat aatcgtcttt tgcaatgtac
     4501 attttaaaaa tttcacacat tcttttttgt atataaagaa cagtgactgg gcacagtggc
     4561 tcatgcctgt aatcccagca atttgggagg ccgaggcggg cgggtctctt gaggccaggg
     4621 gttcgagacc agcctgggca tcatagggag accttcatct ctacaaaaaa tacaaaaatt
     4681 agctgggcat ggtggtgcat gcctgcaatc ccagctaact tggaaggctg aggtgaggtg
     4741 ggaagatcac ttgagcccag gagtttgagg ctgcagtgag ctatgattgc ggcactgcac
     4801 tgcagcctgg gacaatgaga ctgtgtctct aaaaataaaa aaaaaaaaaa catgatacat
     4861 gctattaaaa aagacagcaa agcaggagta taagaaagga aattcacccg aggtcgcagg
     4921 gccttgagta ctcattttgg tgctgattac ctctctgcaa atggacacgg catcataaat
     4981 tggtagtttc ctgctctttt tgtgtaatct tttccagtta atgtgaagcc tctgggggct
     5041 gccctcgtgc actgatggtt gtgtggagtc gggggcggca gtgcgattcc cttttagctg
     5101 ctgcatgggg ggaactcagg ctttccagct gcttcctggg gttccatggg gtagacccct
     5161 caaccgcttc agctgccccg ttaacaggaa ttgacttggt ttcgtttggt gctaccagca
     5221 gtcctgtaat aaactagcta tccatctgta
//
