LOCUS       NM_004274              14984 bp    mRNA    linear   PRI 07-FEB-2025
DEFINITION  Homo sapiens A-kinase anchoring protein 6 (AKAP6), mRNA.
ACCESSION   NM_004274
VERSION     NM_004274.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 14984)
  AUTHORS   Zhang,M., Zhao,Y., Zhao,J., Huang,T. and Wu,Y.
  TITLE     Impact of AKAP6 polymorphisms on Glioma susceptibility and
            prognosis
  JOURNAL   BMC Neurol 19 (1), 296 (2019)
   PUBMED   31759389
  REMARK    GeneRIF: This study provided evidence for the impact of AKAP6
            polymorphisms on susceptibility and prognosis of glioma, suggesting
            AKAP6 variants might have potential roles in the etiology of
            glioma.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14984)
  AUTHORS   Earp,M., Tyrer,J.P., Winham,S.J., Lin,H.Y., Chornokur,G.,
            Dennis,J., Aben,K.K.H., Anton-Culver,H., Antonenkova,N.,
            Bandera,E.V., Bean,Y.T., Beckmann,M.W., Bjorge,L., Bogdanova,N.,
            Brinton,L.A., Brooks-Wilson,A., Bruinsma,F., Bunker,C.H.,
            Butzow,R., Campbell,I.G., Carty,K., Chang-Claude,J., Cook,L.S.,
            Cramer,D.W., Cunningham,J.M., Cybulski,C., Dansonka-Mieszkowska,A.,
            Despierre,E., Doherty,J.A., Dork,T., du Bois,A., Durst,M.,
            Easton,D.F., Eccles,D.M., Edwards,R.P., Ekici,A.B., Fasching,P.A.,
            Fridley,B.L., Gentry-Maharaj,A., Giles,G.G., Glasspool,R.,
            Goodman,M.T., Gronwald,J., Harter,P., Hein,A., Heitz,F.,
            Hildebrandt,M.A.T., Hillemanns,P., Hogdall,C.K., Hogdall,E.,
            Hosono,S., Iversen,E.S., Jakubowska,A., Jensen,A., Ji,B.T.,
            Jung,A.Y., Karlan,B.Y., Kellar,M., Kiemeney,L.A., Kiong Lim,B.,
            Kjaer,S.K., Krakstad,C., Kupryjanczyk,J., Lambrechts,D.,
            Lambrechts,S., Le,N.D., Lele,S., Lester,J., Levine,D.A., Li,Z.,
            Liang,D., Lissowska,J., Lu,K., Lubinski,J., Lundvall,L.,
            Massuger,L.F.A.G., Matsuo,K., McGuire,V., McLaughlin,J.R.,
            McNeish,I., Menon,U., Milne,R.L., Modugno,F., Moysich,K.B.,
            Ness,R.B., Nevanlinna,H., Odunsi,K., Olson,S.H., Orlow,I.,
            Orsulic,S., Paul,J., Pejovic,T., Pelttari,L.M., Permuth,J.B.,
            Pike,M.C., Poole,E.M., Rosen,B., Rossing,M.A., Rothstein,J.H.,
            Runnebaum,I.B., Rzepecka,I.K., Schernhammer,E., Schwaab,I.,
            Shu,X.O., Shvetsov,Y.B., Siddiqui,N., Sieh,W., Song,H.,
            Southey,M.C., Spiewankiewicz,B., Sucheston-Campbell,L.,
            Tangen,I.L., Teo,S.H., Terry,K.L., Thompson,P.J., Thomsen,L.,
            Tworoger,S.S., van Altena,A.M., Vergote,I., Vestrheim Thomsen,L.C.,
            Vierkant,R.A., Walsh,C.S., Wang-Gohrke,S., Wentzensen,N.,
            Whittemore,A.S., Wicklund,K.G., Wilkens,L.R., Woo,Y.L., Wu,A.H.,
            Wu,X., Xiang,Y.B., Yang,H., Zheng,W., Ziogas,A., Lee,A.W.,
            Pearce,C.L., Berchuck,A., Schildkraut,J.M., Ramus,S.J.,
            Monteiro,A.N.A., Narod,S.A., Sellers,T.A., Gayther,S.A.,
            Kelemen,L.E., Chenevix-Trench,G., Risch,H.A., Pharoah,P.D.P.,
            Goode,E.L. and Phelan,C.M.
  TITLE     Variants in genes encoding small GTPases and association with
            epithelial ovarian cancer susceptibility
  JOURNAL   PLoS One 13 (7), e0197561 (2018)
   PUBMED   29979793
  REMARK    GeneRIF: Inherited variants in ARHGEF10L and AKAP6, with potential
            transcriptional regulatory function and association with Epithelial
            ovarian cancer risk, warrant investigation in independent
            Epithelial ovarian cancer study populations.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 14984)
  AUTHORS   Suryavanshi,S.V., Jadhav,S.M., Anderson,K.L., Katsonis,P.,
            Lichtarge,O. and McConnell,B.K.
  TITLE     Human muscle-specific A-kinase anchoring protein polymorphisms
            modulate the susceptibility to cardiovascular diseases by altering
            cAMP/PKA signaling
  JOURNAL   Am J Physiol Heart Circ Physiol 315 (1), H109-H121 (2018)
   PUBMED   29600899
  REMARK    GeneRIF: AKAP6 SNPs found in human patients with cardiovascular
            diseases significantly affect the cAMP/PKA signaling pathway.
            Erratum:[Am J Physiol Heart Circ Physiol. 2019 Feb 1;316(2):H432.
            doi: 10.1152/ajpheart.zh4-2504-corr.2019.. PMID: 30715904]
REFERENCE   4  (bases 1 to 14984)
  AUTHORS   Andrews,S.J., Das,D., Anstey,K.J. and Easteal,S.
  TITLE     Association of AKAP6 and MIR2113 with cognitive performance in a
            population-based sample of older adults
  JOURNAL   Genes Brain Behav 16 (4), 472-478 (2017)
   PUBMED   28067462
  REMARK    GeneRIF: Two single nucleotide polymorphisms (SNPs),
            MIR211-rs10457441 and AKAP6-rs17522122 were genotyped in 1570
            non-demented older Australians of European ancestry.
            AKAP6-rs17522122*T was associated with worse baseline performance
            in episodic memory, working memory, vocabulary and perceptual
            speed, but it was not associated with cognitive change in any
            domain.
REFERENCE   5  (bases 1 to 14984)
  AUTHORS   Lee,S.W., Won,J.Y., Yang,J., Lee,J., Kim,S.Y., Lee,E.J. and
            Kim,H.S.
  TITLE     AKAP6 inhibition impairs myoblast differentiation and muscle
            regeneration: Positive loop between AKAP6 and myogenin
  JOURNAL   Sci Rep 5, 16523 (2015)
   PUBMED   26563778
  REMARK    GeneRIF: Findings indicate a interplay between A-kinase anchoring
            protein 6 (AKAP6) and myogenin.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 14984)
  AUTHORS   Marx,S.O., Reiken,S., Hisamatsu,Y., Jayaraman,T., Burkhoff,D.,
            Rosemblit,N. and Marks,A.R.
  TITLE     PKA phosphorylation dissociates FKBP12.6 from the calcium release
            channel (ryanodine receptor): defective regulation in failing
            hearts
  JOURNAL   Cell 101 (4), 365-376 (2000)
   PUBMED   10830164
REFERENCE   7  (bases 1 to 14984)
  AUTHORS   Kapiloff,M.S., Schillace,R.V., Westphal,A.M. and Scott,J.D.
  TITLE     mAKAP: an A-kinase anchoring protein targeted to the nuclear
            membrane of differentiated myocytes
  JOURNAL   J Cell Sci 112 (Pt 16), 2725-2736 (1999)
   PUBMED   10413680
REFERENCE   8  (bases 1 to 14984)
  AUTHORS   Yang,J., Drazba,J.A., Ferguson,D.G. and Bond,M.
  TITLE     A-kinase anchoring protein 100 (AKAP100) is localized in multiple
            subcellular compartments in the adult rat heart
  JOURNAL   J Cell Biol 142 (2), 511-522 (1998)
   PUBMED   9679148
REFERENCE   9  (bases 1 to 14984)
  AUTHORS   Lester,L.B. and Scott,J.D.
  TITLE     Anchoring and scaffold proteins for kinases and phosphatases
  JOURNAL   Recent Prog Horm Res 52, 409-29 (1997)
   PUBMED   9238861
  REMARK    Review article
REFERENCE   10 (bases 1 to 14984)
  AUTHORS   McCartney,S., Little,B.M., Langeberg,L.K. and Scott,J.D.
  TITLE     Cloning and characterization of A-kinase anchor protein 100
            (AKAP100). A protein that targets A-kinase to the sarcoplasmic
            reticulum
  JOURNAL   J Biol Chem 270 (16), 9327-9333 (1995)
   PUBMED   7721854
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL136298.5, AL132988.4,
            AL117672.5 and AL049781.5.
            
            On Nov 23, 2018 this sequence version replaced NM_004274.4.
            
            Summary: The A-kinase anchor proteins (AKAPs) are a group of
            structurally diverse proteins, which have the common function of
            binding to the regulatory subunit of protein kinase A (PKA) and
            confining the holoenzyme to discrete locations within the cell.
            This gene encodes a member of the AKAP family. The encoded protein
            is highly expressed in various brain regions and cardiac and
            skeletal muscle. It is specifically localized to the sarcoplasmic
            reticulum and nuclear membrane, and is involved in anchoring PKA to
            the nuclear membrane or sarcoplasmic reticulum. [provided by
            RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660803.84315.1, U17195.2
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2144120
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000280979.9/ ENSP00000280979.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-111               AL136298.5         71360-71470         c
            112-469             AL132988.4         44187-44544
            470-721             AL132988.4         146281-146532
            722-2491            AL117672.5         9343-11112
            2492-2614           AL117672.5         41233-41355
            2615-2711           AL117672.5         63523-63619
            2712-2875           AL117672.5         64742-64905
            2876-3024           AL117672.5         142424-142572
            3025-3145           AL117672.5         160103-160223
            3146-3292           AL049781.5         155883-156029       c
            3293-3517           AL049781.5         152601-152825       c
            3518-3733           AL049781.5         114590-114805       c
            3734-7147           AL049781.5         63668-67081         c
            7148-14984          AL049781.5         50799-58635         c
FEATURES             Location/Qualifiers
     source          1..14984
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q12"
     gene            1..14984
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /note="A-kinase anchoring protein 6"
                     /db_xref="GeneID:9472"
                     /db_xref="HGNC:HGNC:376"
                     /db_xref="MIM:604691"
     exon            1..111
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /inference="alignment:Splign:2.1.0"
     exon            112..469
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /inference="alignment:Splign:2.1.0"
     CDS             146..7105
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /note="protein kinase A anchoring protein 6; AKAP-6; AKAP
                     100; A-kinase anchor protein 100 kDa; A kinase (PRKA)
                     anchor protein 6"
                     /codon_start=1
                     /product="A-kinase anchor protein 6"
                     /protein_id="NP_004265.3"
                     /db_xref="CCDS:CCDS9644.1"
                     /db_xref="GeneID:9472"
                     /db_xref="HGNC:HGNC:376"
                     /db_xref="MIM:604691"
                     /translation="MLTMSVTLSPLRSQDLDPMATDASPMAINMTPTVEQGEGEEAMK
                     DMDSDQQYEKPPPLHTGADWKIVLHLPEIETWLRMTSERVRDLTYSVQQDSDSKHVDV
                     HLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNVIVDIHAVQLLWHQLRVSVLV
                     LRERILQGLQDANGNYTRQTDILQAFSEETKEGRLDSLTEVDDSGQLTIKCSQNYLSL
                     DCGITAFELSDYSPSEDLLSGLGDMTSSQVKTKPFDSWSYSEMEKEFPELIRSVGLLT
                     VAADSISTNGSEAVTEEVSQVSLSVDDKGGCEEDNASAVEEQPGLTLGVSSSSGEALT
                     NAAQPSSETVQQESSSSSHHDAKNQQPVPCENATPKRTIRDCFNYNEDSPTQPTLPKR
                     GLFLKEETFKNDLKGNGGKRQMVDLKPEMSRSTPSLVDPPDRSKLCLVLQSSYPNSPS
                     AASQSYECLHKVGNGNLENTVKFHIKEISSSLGRLNDCYKEKSRLKKPHKTSEEVPPC
                     RTPKRGTGSGKQAKNTKSSAVPNGELSYTSKAIEGPQTNSASTSSLEPCNQRSWNAKL
                     QLQSETSSSPAFTQSSESSVGSDNIMSPVPLLSKHKSKKGQASSPSHVTRNGEVVEAW
                     YGSDEYLALPSHLKQTEVLALKLENLTKLLPQKPRGETIQNIDDWELSEMNSDSEIYP
                     TYHVKKKHTRLGRVSPSSSSDIASSLGESIESGPLSDILSDEESSMPLAGMKKYADEK
                     SERASSSEKNESHSATKSALIQKLMQDIQHQDNYEAIWEKIEGFVNKLDEFIQWLNEA
                     METTENWTPPKAEMDDLKLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELIASHKAG
                     LKDMLRMIASQWKELQRQIKRQHSWILRALDTIKAEILATDVSVEDEEGTGSPKAEVQ
                     LCYLEAQRDAVEQMSLKLYSEQYTSSSKRKEEFADMSKVHSVGSNGLLDFDSEYQELW
                     DWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKTELLSKVEALKKGGVLL
                     PNDLLEKVDSINEKWELLGKTLGEKIQDTMAGHSGSSPRDLLSPESGSLVRQLEVRIK
                     ELKGWLRDTELFIFNSCLRQEKEGTMNTEKQLQYFKSLCREIKQRRRGVASILRLCQH
                     LLDDRETCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESETLNVIDP
                     GLMDLNGMSEDALEWDEMDISNKLISLNEESNDLDQELQPVIPSLKLGETSNEDPGYD
                     EEADNHGGSQYASNITAPSSPHIYQVYSLHNVELYEDNHMPFLKNNPKVTGMTQPNVL
                     TKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNSGSESGIVSEGDTETTTNS
                     EMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESIKLPNSSQSSISPVGCV
                     NGKVGDLNSITKHTPDCLGEELQGKHDVFTFYDYSYLQGSKLKLPMIMKQSQSEKAHV
                     EDPLLRGFYFDKKSCKSKHQTTELQPDVPPHERILASASHEMDRISYKSGNIEKTFTG
                     MQNAKQLSLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLF
                     SCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQSSSQKMSF
                     TGQMSLDIASSINEDSAASLTELSSSDELSLCSEDIVLHKNKIPESNASFRKRLTRSV
                     ADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCIKDEDDDSSIATDDE
                     IYEDCTLMSGLDYIKNELQTWIRPKLSLTRDKKRCNVSDEMKGSKDISSSEMTNPSDT
                     LNIETLLNGSVKRVSENNGNGKNSSHTHELGTKRENKKTIFKVNKDPYVADMENGNIE
                     GIPERQKGKPNVTSKVSENLGSHGKEISESEHCKCKALMDSLDDSNTAGKEFVSQDVR
                     HLPKKCPNHHHFENQSTASTPTEKSFSELALETRFNNRQDSDALKSSDDAPSMAGKSA
                     GCCLALEQNGTEENASISNISCCNCEPDVFHQKDAEDCSVHNFVKEIIDMASTALKSK
                     SQPENEVAAPTSLTQIKEKVLEHSHRPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEEK
                     SSTPLPLDTTDSGLDDKEDIECFFEACVEGDSDGEEPCFSSAPPNESAVPSEAAMPLQ
                     ATACSSEFSDSSLSADDADTVALSSPSSQERAEVGKEVNGLPQTSSGCAENLEFTPSK
                     LDSEKESSGKPGESGMPEEHNAASAKSKVQDLSLKANQPTDKAALHPSPKTLTCEENL
                     LNLHEKRHRNMHR"
     exon            470..721
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /inference="alignment:Splign:2.1.0"
     exon            722..2491
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /inference="alignment:Splign:2.1.0"
     exon            2492..2614
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /inference="alignment:Splign:2.1.0"
     exon            2615..2711
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /inference="alignment:Splign:2.1.0"
     exon            2712..2875
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /inference="alignment:Splign:2.1.0"
     exon            2876..3024
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /inference="alignment:Splign:2.1.0"
     exon            3025..3145
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /inference="alignment:Splign:2.1.0"
     exon            3146..3292
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /inference="alignment:Splign:2.1.0"
     exon            3293..3517
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /inference="alignment:Splign:2.1.0"
     exon            3518..3733
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /inference="alignment:Splign:2.1.0"
     exon            3734..7147
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /inference="alignment:Splign:2.1.0"
     exon            7148..14984
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8086..8091
                     /regulatory_class="polyA_signal_sequence"
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /note="hexamer: AATAAA"
     polyA_site      8117
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /note="major polyA site"
     regulatory      8333..8338
                     /regulatory_class="polyA_signal_sequence"
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /note="hexamer: AATAAA"
     polyA_site      8351
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
     regulatory      11279..11284
                     /regulatory_class="polyA_signal_sequence"
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /note="hexamer: ATTAAA"
     polyA_site      11299
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
     regulatory      14962..14967
                     /regulatory_class="polyA_signal_sequence"
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
                     /note="hexamer: ATTAAA"
     polyA_site      14984
                     /gene="AKAP6"
                     /gene_synonym="ADAP100; ADAP6; AKAP100; mAKAP; PRKA6"
ORIGIN      
        1 atctgaactg atgtcacagc atcatgcagc aggtcaaaca aggcatctcc tagtattgca
       61 tcctacagat gtgctgtaaa catcaaaaga agacggtggg atcaggagat gctgttttgg
      121 aaagaagtga ggtttagact tctccatgtt aaccatgagc gtgacacttt cccccctgag
      181 gtcacaggac ctggatccca tggctactga tgcttcaccc atggccatca acatgacacc
      241 cactgtggag cagggtgagg gagaagaggc aatgaaggac atggactctg accagcagta
      301 tgaaaagcca cccccactac acacaggggc tgactggaag attgtcctcc acttacctga
      361 aattgagacc tggctccgga tgacctcaga gagggtccga gacctaacct attcagtcca
      421 gcaggattcg gacagcaagc atgtggatgt acatctagtt caactaaagg acatttgtga
      481 agatatttct gatcatgttg agcaaatcca tgccctcctt gaaacagagt tctccctaaa
      541 gctgctgtct tactctgtca acgtgatagt ggacatccac gcagtgcagc tcctctggca
      601 ccagcttcga gtctcagtgc tggttctgcg ggagcgcatt ctgcaaggtc tgcaggacgc
      661 caatggcaac tacactaggc agacggacat tctgcaagct ttctctgaag agacaaaaga
      721 gggccggctt gattctctaa cagaagtgga tgactcagga caattaacca tcaaatgttc
      781 tcaaaattac ttgtctctgg attgtggcat tactgcattc gaactgtctg actacagtcc
      841 aagtgaggat ttgctcagtg ggctaggtga catgacctct agccaagtca aaaccaaacc
      901 ctttgactct tggagctaca gtgagatgga aaaggagttt cctgagctta tccgaagtgt
      961 tggtttactt acggtagctg ctgactctat ctctaccaat ggcagtgaag cagttactga
     1021 ggaggtatct caagtatctc tctcagtaga cgacaaaggt ggatgtgagg aagacaatgc
     1081 ttctgcagtc gaagagcaac caggcttaac actgggggtg tcatcatctt caggagaagc
     1141 tctgacaaat gctgctcaac cctcctctga gactgtgcag caagaatcca gttcctcctc
     1201 ccatcatgat gcaaagaatc agcagcctgt tccttgtgaa aatgcaaccc ccaaacgaac
     1261 catcagagat tgctttaatt ataacgagga ctctcccacg cagcctacat tgccaaaaag
     1321 aggacttttt cttaaagagg aaacttttaa gaatgatctg aaaggcaatg gtggaaagag
     1381 gcaaatggtt gatctaaagc ctgagatgag cagaagcacc ccttcgctag tagatcctcc
     1441 tgacagatcc aaactttgcc tggtattgca gtcttcttac cccaacagcc cttctgctgc
     1501 cagccagtct tatgagtgtt tacacaaggt ggggaatggg aaccttgaaa acacagtcaa
     1561 atttcacatt aaagaaattt cttccagcct gggaaggctt aacgactgct ataaagagaa
     1621 atctcgactt aaaaagccac acaagacctc agaagaggtg cctccatgcc gaacacctaa
     1681 acgggggact ggttcaggca aacaagctaa aaatacaaag agctcagcag tgccaaatgg
     1741 agagctttct tatacttcca aggccataga ggggccacaa acaaattctg cttccacatc
     1801 ctcacttgag ccttgtaatc agagaagttg gaatgccaaa ttgcaattgc agtcagaaac
     1861 atccagttca ccagctttta ctcagagcag tgaatcctct gttggctcag acaacatcat
     1921 gtctccggtg ccacttcttt caaaacacaa aagcaaaaaa ggtcaagcct cctctccaag
     1981 tcacgtcact aggaatggtg aggttgtgga ggcctggtat ggctctgatg aatacctagc
     2041 actgccctct caccttaagc agacagaagt attggctttg aagttggaaa acctaacaaa
     2101 gcttctgcct cagaaaccca gaggagaaac catccagaat attgatgact gggaactgtc
     2161 tgaaatgaat tcagattctg aaatctatcc aacctatcat gtcaaaaaga agcatacaag
     2221 gctaggcagg gtgtctccaa gctcatctag tgacatagcc tcttcactag gggagagcat
     2281 tgaatctggg cccctgagtg acattctttc tgatgaggag tccagtatgc ctctcgctgg
     2341 catgaaaaag tatgctgatg agaagtcaga aagagcttca tcctctgaga aaaatgagag
     2401 ccattctgcc actaaatcag ctttaattca gaaactgatg caagatattc agcaccaaga
     2461 caactatgaa gccatatggg aaaaaataga ggggtttgta aacaaactgg atgaattcat
     2521 tcaatggtta aatgaagcca tggaaactac agaaaattgg actcccccta aagcagagat
     2581 ggatgacctt aaactgtatc tggagacaca cttgagtttt aagttgaatg tagacagtca
     2641 ttgtgctctc aaggaagctg tggaggagga aggacaccaa cttcttgagc ttattgcatc
     2701 tcacaaagca ggactgaagg acatgctgcg gatgattgca agtcaatgga aggagctgca
     2761 gaggcaaatc aaacggcagc acagctggat tctcagggct ctggatacca tcaaagccga
     2821 gatactggct actgatgtgt ctgtggagga tgaggaaggg actggaagcc ccaaggctga
     2881 ggttcaacta tgctacctgg aagcacaaag agatgctgtt gagcagatgt ccctcaagct
     2941 gtacagcgag cagtatacca gcagcagcaa gcgaaaggaa gagtttgctg atatgtcaaa
     3001 agttcattca gtgggaagca atgggcttct ggactttgat tcagaatatc aggagctctg
     3061 ggattggctg attgacatgg agtcccttgt gatggacagc cacgacctga tgatgtcaga
     3121 ggagcagcag cagcatcttt acaagcgata cagtgtggaa atgtccatca gacacctgaa
     3181 aaagacggag ctgcttagta aggttgaagc tttgaagaaa ggtggcgttt tactaccaaa
     3241 tgatctcctt gaaaaagtgg attcaattaa tgaaaaatgg gaactgcttg ggaaaaccct
     3301 aggagagaag atccaggaca caatggcagg gcacagtggg tcgagtccac gtgacctgct
     3361 ctctcctgaa agtggaagcc tggtaaggca gctggaggtc aggatcaaag aactgaaagg
     3421 atggctaaga gatacagagc ttttcatctt caattcctgt ctgagacaag aaaaggaagg
     3481 aacaatgaat actgagaaac aactgcaata ctttaagtcc ctctgtcgtg aaatcaagca
     3541 acgacgtcga ggagttgcct ccattctgcg actatgccag catcttttgg atgaccggga
     3601 gacttgcaat ctgaatgcag accaccagcc catgcagctg atcattgtaa atcttgaaag
     3661 aaggtgggaa gccattgtca tgcaagccgt ccagtggcaa acacgtctac aaaagaagat
     3721 gggaaaggaa tctgagactt tgaatgtgat tgatcctggc ttgatggacc taaatgggat
     3781 gagtgaggat gccctggaat gggatgaaat ggacataagt aacaagttaa ttagtttgaa
     3841 tgaggaatca aatgaccttg atcaagaact ccaacctgtt atcccttcct tgaagcttgg
     3901 agagacaagt aatgaggacc ctggttatga cgaggaggct gataaccatg ggggatctca
     3961 gtatgcctca aatattactg ccccctctag tccacacatt taccaggtgt acagcctcca
     4021 caatgttgaa ctctatgagg acaaccacat gccatttctg aaaaacaatc caaaggtcac
     4081 tggcatgaca cagcctaatg ttttaactaa gagtctcagt aaagactctt cattttcatc
     4141 taccaaatct ttgccagatc ttctaggtgg ttccaatttg gtaaagccct gcgcatgtca
     4201 tggaggagac atgagccaga attcaggcag tgagagtgga attgtcagtg aaggagacac
     4261 agaaaccact accaactctg aaatgtgctt gctcaatgca gtggatgggt ccccaagtaa
     4321 ccttgaaact gaacatctgg acccacaaat gggagatgca gttaacgtgt taaagcaaaa
     4381 atttacagat gagggggaaa gcattaagct tccaaatagc tctcagtcgt ccatttcacc
     4441 agtgggttgt gtaaatggaa aagttggaga tttaaacagt attaccaaac atacccctga
     4501 ctgtttggga gaagaattac aaggaaaaca tgatgtgttt acattttatg attactcata
     4561 cctccaaggc tcaaaactca aattaccaat gataatgaaa cagtcacaaa gcgaaaaagc
     4621 gcatgtggag gatcccctgc ttcgtggttt ttattttgat aaaaaatcat gcaaatctaa
     4681 acatcagact acagagttac aaccagatgt acctccccat gaaaggattt tggcaagtgc
     4741 atctcatgaa atggatcgca tttcatataa aagtggcaat atagaaaaga cattcactgg
     4801 catgcagaat gccaaacagc tctccctttt atctcatagt tcatctattg agtccctttc
     4861 tccagggggt gatttatttg gattgggcat ctttaaaaat ggcagtgaca gcctccagcg
     4921 aagcacttct ttagaaagtt ggttgacttc ctataaaagc aatgaagatc tctttagctg
     4981 tcacagctct ggggatataa gcgtgagcag tggctcagtt ggtgaactaa gtaaaagaac
     5041 attagatctc ctgaatcgtt tggagaatat ccagagcccc tcagagcaaa agataaaacg
     5101 aagtgtttct gatatcactc ttcaaagcag ttcccaaaag atgtccttta ctggccagat
     5161 gtcattggac atagcatctt ctatcaatga agactcagcg gcatctctaa cagaacttag
     5221 cagcagtgac gagctctctc tttgctcaga ggatattgtg ttacacaaga acaagatccc
     5281 ggaatcgaat gcatcgttca ggaagcgtct gactcgttca gtggctgatg aaagcgatgt
     5341 caatgtcagc atgattgtta atgtctcttg cacctctgct tgcactgatg atgaagatga
     5401 cagcgacctg ctctccagct ctacccttac cttgactgaa gaagagctgt gcatcaaaga
     5461 tgaggatgac gactccagta ttgcaacaga tgatgaaatt tatgaagact gcaccttgat
     5521 gtcagggcta gactacataa agaatgaatt acagacctgg attaggccaa aattgtcttt
     5581 gacaagagat aagaaaaggt gcaatgtcag tgatgagatg aagggcagta aagatataag
     5641 tagcagtgag atgaccaatc cctctgatac tctgaatatt gagacccttc taaatggctc
     5701 tgtaaaacgt gtctctgaaa ataatggaaa tggtaagaat tcatctcata cccatgagtt
     5761 agggacaaag cgtgaaaata agaaaactat tttcaaagtt aataaagatc catatgtggc
     5821 tgacatggaa aatggcaata ttgaaggtat tccagaaagg caaaagggaa aaccgaatgt
     5881 gacttcaaag gtatcagaaa atcttggttc acatgggaaa gagatttcag agagtgagca
     5941 ttgtaagtgt aaagcactta tggatagttt agatgattca aatactgctg gcaaggaatt
     6001 tgtttcccaa gatgttagac atcttccaaa gaaatgtcca aatcaccacc attttgaaaa
     6061 tcaaagcact gcctctactc ccactgagaa gtctttctca gaactggctt tagaaaccag
     6121 gtttaacaac agacaagact ctgatgcact gaaatcatct gatgatgcac cgagtatggc
     6181 tggaaaatct gctggttgtt gcctagcact tgaacaaaac ggaacagagg aaaatgcttc
     6241 tatcagcaac atttcctgtt gcaactgtga gccagatgtt ttccatcaaa aagatgccga
     6301 agattgttca gtacacaact ttgttaagga aatcattgac atggcttcga cagccctaaa
     6361 aagtaaatct caacctgaaa acgaggtggc tgctcctact tcattaactc aaatcaagga
     6421 gaaagtgttg gagcattctc accggcccat ccagctgaga aaaggggact tttattcgta
     6481 cttatctctc tcatctcatg acagtgattg tggggaggtc accaattaca tagaagagaa
     6541 aagcagcact ccattgccac tagacaccac tgactcgggc ttagatgaca aggaagatat
     6601 tgaatgcttt tttgaggcct gtgttgaggg tgactctgat ggagaggagc cttgtttctc
     6661 tagtgctcct ccaaatgaat ctgcagttcc cagcgaagct gcaatgccac tacaagcaac
     6721 agcatgttct tctgagttca gtgatagttc tctttcagct gatgatgcag atacagtggc
     6781 tctttcaagt ccttcctctc aggaaagagc tgaggttgga aaggaagtga atggtttgcc
     6841 ccaaacttcc agtggctgtg cagaaaactt agagtttact ccttcaaagc ttgacagtga
     6901 aaaggaaagt tccggaaaac caggtgaatc tggaatgcca gaagaacata atgctgcttc
     6961 agccaaatct aaagttcaag acctctcctt gaaggcaaat cagccaacag acaaggccgc
     7021 attgcatccc agccccaaaa ctttaacctg tgaagaaaat cttctaaacc ttcatgaaaa
     7081 acgacataga aatatgcata ggtagaatgt accccctccc caagcatgaa aatcatctca
     7141 ctgaaagata cgcctggctg caactcaggg gtggcctcat cctcccgccc tgggctggcc
     7201 tctggttcca tcacgtttgt cactgccgtt tattacattg acttctccca agatgaatct
     7261 tccttccaaa tgtgttttct ccacacaagc cttgtgatct gaatgtgtgc gctggttctc
     7321 tttaggtgat cgtctttgaa gttcagcaaa gctgcttgtt ctcccatgga ttcctgtccc
     7381 aagctacctc taccaaccct ctctctccag ctagactttt ctctttgcct cctcccttcc
     7441 cttccactct ttaaagttct gcagttcacc aactggtagt ccattaaatt ctcctgtcta
     7501 gaatgacccc cccaccagta cttgaccaat ttcatgtatc aatctggatt tttttttaac
     7561 ggtataatga ctgtgtttat tgaaagagtt ttacctaaaa agccaacatt tgaattggtt
     7621 gcagcataga gaagaaacac tggtccttct ttcaaaatta agcaactatt aaaagcgcca
     7681 ttttatttat ttcatttaaa aaataatcta tgcagcattt caagaaacaa ccatatggtg
     7741 ttgtatatta taaactggtg acattctact attgaattat gtacaacatt ttcatttttt
     7801 atgcttcttg aggtggtaat gagaaaaaag ttttttaaaa aagtgtgcct tgctgtattt
     7861 cttataccat ttattaaaaa gctgctttca cggtaaaatt atgttggttt gaaaggagga
     7921 aatagcaagg ttaagatgtg tgaataattt ctgtatatat gtataaccaa gtacaaacat
     7981 tgatgtataa tgacagtata aaatgctttc atgtttgtga tgtctagtga tgtggaaaat
     8041 ataagcctta aatccattag attgcatggt aattaaaatt ggcataataa acacagatta
     8101 ttgggggaaa aggaaaatta gtgatctctt ctactatgtt ctttaccaaa ttgttgcatc
     8161 tggttctgaa aaagtatagc atgtagcagc ttccaaacat attcatattg cttaagaggc
     8221 ttaacattac ctaaactaga gactagacgt aaagccttca gttttcaaaa tctttctggt
     8281 cactataaag atcttggaac agcaaatgat taaatgtcag ttcccctaaa ccaataaaca
     8341 tttatactag attttttatt tccacttatc attaatgatt taatgttgga tttcaggtac
     8401 cttgtatgtc ttaatttatt ttaaatattt attttgaatg agtttgatag aaagctagta
     8461 gaaaagtaca gaaaatttga ctattattta tagatttcag gtatatttat atgtgtaaaa
     8521 gaaattgaca aagaaatatt tcatctggcc tttactgact cctgttaaat gcagttttaa
     8581 atttatatcg taacacctac ttaagtgcct gacacagtag gtattcaata aaaatttact
     8641 gaattaaagg attaaattag gtgacatggt gacatctatc cctttatttt gacactaaaa
     8701 catggacaca actagaaaga ggtacaatgc aatataaagt cacaatagat aatatatatc
     8761 aaatttctaa aaggtaaaga atgttgtggg ttcatgcagt cacaggaatg acaatcattc
     8821 aacagatagt tcagaaacac tttttatctg caaggcacta ttctagatcc agaagatgca
     8881 atgttgaaca aacagacaaa gccctgccct cagaaggctg tcctgcatta ggaacaagtg
     8941 aacacgcaaa tgacatgaag tatttgttgc agagctgagg aacagagcaa atgtagtgat
     9001 agaagcgcaa tgagagaagc agcagtgggt acaaggagga agaaaaaggg cttgcagaga
     9061 gtggaaagtt agtggaatat tcatgaaact tcattgcagg ggtaatagaa gaaaaagtaa
     9121 attgggagga cttaatggaa ggtcttttaa aaagttaact tggagcttct gtatgtaaaa
     9181 tgctaggtaa taaggacact ttgtacaggc tgttttgcac ctgattttat ttatcattag
     9241 tgccacgcca agatcattta gacgatgctt atctgtaatt ctaccacttt aataactatt
     9301 tgtattttta tgccccttct gatcttttcc atatgtattt ctaaatggat aaattattct
     9361 aggcttctta ataggtagta atttgttcaa aagcggtttt agccagacat ctagttgcag
     9421 tgttcaagag gattatgggg gaaagagatt agagataatt gtctagttag ggggcagctg
     9481 gagaaaataa gctaagtttg caataacaga gtacacaagt atagtggccc aggatgtagt
     9541 gaaagaacaa atcctagagt ctttgaaatt tctaagggca ttctagacct ctgttgggat
     9601 atggtattat tttacatact gacacaacct aaattttctt tgggtagtaa ctaatgtcaa
     9661 gtctacatcg actggtaaaa cattcaaaga acaaactgac aatgatgttc tacctacttg
     9721 ttacatgctc atggaagacc gtgcagtatt gaaagtattt gttaattatc tgcttagtat
     9781 taacactaaa tttgtagaat gactttcagg tttgttgaac aatgcctttt caggttggaa
     9841 gaagaaaaat agcctcaatc tcccacccca tgtaggcact acctccccaa ttacccttag
     9901 aaaatgatca caccaactct gcctacacac ttccagtgat agtggctcat tgtctgttaa
     9961 ggcaaactgt tccactgttg ggcatatctc tttgttagaa agttctttct taggttgcta
    10021 aaatctgcct agtaccccgc taccctgttc tgtcttatgg agcagcccag attatcttta
    10081 ctccctcttt ctcatggcaa ccctgaagat aatcaaggcc agttactcat catctcccaa
    10141 ccactgtttc ctcaactgcc cttcatatgt catggttttc agatccattc caacctgact
    10201 gaatgttaac agacagaatt cttcacatta aggaactgtc ttcatcatca tacatgtaga
    10261 aaagaatctg aacatttaag tgcgaagttt tctctagaaa tatattcaag atatgtttat
    10321 tctattattg taaatttcaa acaataaata aataagaatc catgacttcc ttcagtggcc
    10381 cagtccagtg cctaagtcat ctggaatctt ctccttacat cgaatacaaa cctaacctgt
    10441 ttccaagtag ggcactccct ccgcttattt attcatttat tcagccattc agcaaacatt
    10501 tattaaatgg ctacctatgt gaggcactat atttggcatt aggtatataa aggcaactaa
    10561 cacatggtat ctgtctccaa aggtttacag cttttcttct gaaagtgcct tttgtgtcct
    10621 tgaatagagt gattatgact tttgtctcaa ttaaatgatg acctcattta gtttctgatg
    10681 aagtttctct acatttaaga aaatctagtg agcaaaacgg tatacaaaaa atcatctgga
    10741 tctgactacc agaaaaagta aagtggtttt aattacagaa agaaaaatat ttgttagatt
    10801 tctggtcact gaataaatat gcatcttata caacacagaa caacctaaat ttagggcttc
    10861 tggaaacctg agtttgatga ctttgttgtg tttggttcat ccggactagg tttcacccat
    10921 tctataattc ctagaaacaa actagatgaa aatatcaatg aaatgatcca ggtctgtctt
    10981 acaagtcaat ttgctttagc ttccaaaaga agttgaaatt ttttagaatt ttaaagaaaa
    11041 actcactttt caagtgtcat ataattctta tattttaaat ataaatcgaa ccaactaaat
    11101 ttaccgctat atttttttct acatattctt ttttcaattt tcattttgaa aaaattcaga
    11161 cctatgtaaa agttgagagt agaacaaaga tacttggtac tcatccctca ggttcattta
    11221 ttgttaatat ttcaccatat ttacttcatc tctgtataca cacacacttt tttgtatgat
    11281 taaatcattt gaaattaaat tgtagagtat gatacttcat ctgcaaatac ttcagcatgt
    11341 gttagctgag aacatgggta ttcttctgca agtctacaat accatcttca tactcaagaa
    11401 atgtaacatt ggctggtcat ggtggctcac gcctgtaatc ccagcacttt gggaggccaa
    11461 ggcgtgtgga tcacctaagg tcaggagttc gagatcagcc tggccaacat ggtgaaaccc
    11521 cgtctctact aaaaatacaa aaattagcca ggcgtggtag ctgtaatccc agctacttgg
    11581 gaggctgagg caggagaatt gcttgaagcc aggaggcaga ggttgcagtg agccgagatt
    11641 gcaccactgc actccagcct gggcaagaag agtgaaattt tgtctcaaaa aaaaaaatgt
    11701 aatattaata caataatacc tgatagttta tattcaagtt tctctaacta cccaaattat
    11761 gtcctcttat agttgttttt gttttaatac agtattcaaa caaagatcac acactgcttt
    11821 tagtttccaa gtcttttttt tttttttttt ttttaaatct tgcatagttt ccctgtgctt
    11881 ttactctatt tttctttggg cttttataac atcgacagtt ctgaaaagtc caggccagtt
    11941 ttgcagaatg atccacaatc ttgatgggtc tagttgtttt ctcattgtta aactcagggt
    12001 aaactttttt ttgtcaagta aatacatagg tgactttgca ttcacagcca ctctttaatg
    12061 aagattgatt gaataactga cattcctgat atgttttaaa gttcacagct tactctttca
    12121 gcccatgctt catccatcta aggcaagggt cagcaaactg tggcacgtgg gccaaattca
    12181 gctcgttgcc tgttctggtt tgacccattt gaacaattga cgagcttcaa acaattttta
    12241 cattttttag tagttaaaca aaagaatact tcatgacatg tgaaaatcat atgaaattta
    12301 aattttggtg tccatgtata aagttttatt agaacacatc cacgcacatt tgtttccata
    12361 gtctacggat gctttgacac tatacaaagt tacgtacttg caacaaaagc catatggcct
    12421 gcaaaaccta aaacatttac tatctggatc attacagaaa gttttctgat ccctggtcta
    12481 tgatattcta aattccgaca cattttctta ggatagattt ccatttgcaa attcagtgta
    12541 agacataaac accggcaata gttgtgtttt ttttttcttt ttacttccta gattttattg
    12601 cattctcaac ttgtttcata ttaccttaaa aaataaagtg cacttaaaga ttgtttcaca
    12661 tccacagttt gtttaaggat ttaaatttag ttcactatta ctgcctggct ttgattgatt
    12721 tagagggtta gtcaattaca gactaaataa ttagttcaat caaaaccatc agaaaaattg
    12781 acacaaactc acttccatgc accagtaaac tggaatcctt tctttaaatg tttttctaaa
    12841 gcaatccgag gaattaaatt caggccattt cacagtcagt ttttttcaaa ttcatttttc
    12901 aactcaaagg caaaaccatg atcaaaatat tgtatatagt acaccttcag ttcccaactg
    12961 ctgaatttac caaggaatta agtattcacc acaaaccctg gtgtggccat aggtggacac
    13021 tctaattaaa aagaagatgt tcaaaaagaa tagtccttct tttctttctt aaattcacct
    13081 ttgatagcac tgccacactt ctgggaaggg aacgttcaag gaaaccgtat agccacttct
    13141 tttttaaaag cagccacata ccttctatat aacaatggcc ctttagtttg agagttgcca
    13201 catatttgca tttccagagt aaaataatag gatgacatgg gcaggtcagg cccacaatag
    13261 tatggtttct ttggcaaagg cattttggcc aatgccgtaa gaccattctg gcccttgatt
    13321 aatgggttct caccaaagca gaaattacgc agagcttatt tgtccttgca ttttgaagta
    13381 aatcattgcc tgcataaagc aactcttttg tctcttttcc attgcaacac acaggagttg
    13441 gaatgtgttc atacgtgtaa gactgtctta gtctgcccag actgcttgga ctgtgttgtt
    13501 tataaacaac agaatttact gctcaaagtt ctggagactg ggaagttcaa gatcaagatg
    13561 ctagcagatt cagtgtctga ggagggctca ctttctgttt cattgatgca ccttactgca
    13621 tcctcatctg gtggaagggg cagtgaacaa gctcccttgg gcccctttta cgaaagcact
    13681 aattccattc atgaagactt cacaacttaa tcacctccca aaggctccat ctcttaatac
    13741 gatcacattg gggattaggt ttcaacatac caattttggg ggtacacaaa tattgaggtg
    13801 atagacactt ccaggctttt gccaaacatt agtaaacaat ttccagtgaa tactctgccc
    13861 cattctctcc tactcaagca gagtatctta aggcagcaga ttggagtgac gttactttaa
    13921 gggtaacttt gaagccaatc taattcatac tcaaaaaagt attccaaaat tttggtactc
    13981 tattatgggt tacaaacccc ttgtgacacc atatttaaga gccactgcta ttgaggcttg
    14041 cactctcttg cttgaaatga ggtgctccca aacctgggag atggctccca aagaacaaga
    14101 gaatcaaccc catcgtgcat ttatgtgctg ccccaggtaa tccacaggca caaagaactt
    14161 gagcttcctg gtgtgttctt cagaaaaaaa ggaattcaaa aagcaaatgt aaaatggaac
    14221 agaacttggc ctcaaagtga tgttggaaaa atagccagtc ctgatgactt ggtcgaggta
    14281 acttgctttg cccactgtta actacagagc catatgataa tggaacatca aggttttcca
    14341 gataaaccca aagccttttg tgtctatacc ttgtaacctg tcatgttcat caacgtttta
    14401 gactgtacca ttgctctttc tcccttcttt attcatttta tatggggacg tttgactagg
    14461 atcaccagat gtagatttgg taatttttcc ataccattaa gatgtatgat aatggatttt
    14521 attaatttaa cacaaatgca taaaaatatg atgtaataag aaacaatcct gaaattatta
    14581 aaacatttct ttgtccttac ttaaacctaa cctgccattt taaaagacac ctaactctat
    14641 aaacaaatgg gccattacag acgtaaaaca aatattattc agtgaaattt attcaaggac
    14701 ttaaaatgat tgaaggcatt aggaacataa aaatgcataa gatcctcttt taaatcccaa
    14761 tattccctaa ccactggttt ataaaaaata ctctaaggtt tatagaatta gtttggttcc
    14821 gttagttgat caagttactt acactaagtc agcaattcaa aacaaataat tccctctgtg
    14881 tgtgtttgtt tgcttgcaaa tatgtttcat tttaaagtgt ctttttatat agaaagccaa
    14941 gttggtggaa tttatcttgt cattaaaatg atgtgaaaat caaa
//
