LOCUS       NM_001080482            4642 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens apical junction component 1 homolog (AJM1), mRNA.
ACCESSION   NM_001080482 XM_372159
VERSION     NM_001080482.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4642)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL355987.31.
            
            On Feb 8, 2021 this sequence version replaced NM_001080482.4.
            
            ##Evidence-Data-START##
            CDS exon combination :: ERR4352441.415695.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA1968540, SAMEA2142348 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000436881.3/ ENSP00000412388.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-112               AL355987.31        120963-121074
            113-196             AL355987.31        122681-122764
            197-4642            AL355987.31        122841-127286
FEATURES             Location/Qualifiers
     source          1..4642
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q34.3"
     gene            1..4642
                     /gene="AJM1"
                     /gene_synonym="ajm-1; C9orf172"
                     /note="apical junction component 1 homolog"
                     /db_xref="GeneID:389813"
                     /db_xref="HGNC:HGNC:37284"
     exon            1..112
                     /gene="AJM1"
                     /gene_synonym="ajm-1; C9orf172"
                     /inference="alignment:Splign:2.1.0"
     exon            113..196
                     /gene="AJM1"
                     /gene_synonym="ajm-1; C9orf172"
                     /inference="alignment:Splign:2.1.0"
     exon            197..4642
                     /gene="AJM1"
                     /gene_synonym="ajm-1; C9orf172"
                     /inference="alignment:Splign:2.1.0"
     CDS             256..3186
                     /gene="AJM1"
                     /gene_synonym="ajm-1; C9orf172"
                     /note="uncharacterized protein C9orf172"
                     /codon_start=1
                     /product="apical junction component 1 homolog"
                     /protein_id="NP_001073951.2"
                     /db_xref="CCDS:CCDS48059.1"
                     /db_xref="GeneID:389813"
                     /db_xref="HGNC:HGNC:37284"
                     /translation="MTRTDPPDLLVSTVYQDIKVATPGPASKCSPCERSVARPAEPAP
                     FNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPPG
                     LTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGR
                     VAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARP
                     APQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPP
                     GPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTF
                     PIQEPPSRSYYGEAPRAYGLPYGPRYVPEEPRAHSTARPFYTEDFGRYRERDVLARTY
                     PHPRSSPAWADWGPRPYRTLQVVPPSDPDPLLASWHGGTGTSPPRLATDSRHYSRSWD
                     NILAPGPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPVVVNLSTSPRRYAALSL
                     SETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWELPGGRTRPPPHAAP
                     DGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQLRRLLDSRPAGSGAP
                     ALAPPRSPPASAGSAEEPAAPGEAADASPEPSADEDDLMTCSNARCRRTETMFNACLY
                     FKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSGPVHRAFSRIA
                     RVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARE
                     LAAAGRLYEPAECFLLSVSVAVGPGTAPPGTPALPAPAPRSHGPTVRKFAKVALAAGS
                     PARPPPARSREPDMETLILTPPPGTAGLDQDGEAGRRAREVAFIHIQRELRLRGVFLR
                     HEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASANLL
                     DDIM"
     regulatory      4621..4626
                     /regulatory_class="polyA_signal_sequence"
                     /gene="AJM1"
                     /gene_synonym="ajm-1; C9orf172"
                     /note="hexamer: AGTAAA"
     polyA_site      4642
                     /gene="AJM1"
                     /gene_synonym="ajm-1; C9orf172"
                     /note="major polyA site"
ORIGIN      
        1 gctgctgcct ggaagcttct gcccgtgccg gggacgcagc agtgccgggg acacagagga
       61 gccgacctgg gggtggcaca gcccaccggg gcacagccag agcagcaccc aggtgcttct
      121 gaccccggca tggaggaagc gcccgcgttc tcggcccagg cccgcagcca gggctgctcc
      181 gcccgctgcg ccccagggca aaagccccgc aaggcagtgt gagctggagc cgccagcctg
      241 gggacctctt ttaagatgac ccgtacggac cctccggacc tgctggtgtc gaccgtgtac
      301 caggacatca aggtggcgac cccgggaccc gcgtccaagt gctcgccatg tgagcgatcc
      361 gtggcccggc ctgctgagcc cgcgcctttc aacaagcgcc actgccgcag cttcgacttc
      421 ctggaggcgc tggacgggcc ggccatggag accctgccgg agccaccgcc gccggagtcc
      481 gctgtgccgc gcgcccggac ccgcgaagcc gagccacgcc gccgcgcccg ctccaagagt
      541 gcgccccgcg cgcccccggg cctgacgccc gcgcccgcct cgccgccggt gttgccccgc
      601 cgagggcggg aggcccagcg tgcggcgcgg gccgaggcat cgccgcgccg ggagcccgcg
      661 tacccggcgc tccgcgccct tgccaacgag ctgcatccca tcaagttgca gccgcagcgg
      721 ggcggccccg gccgcgtcgc gcccctgtgc gccgccgcgg gccgctgcgc accgcccgag
      781 ccacccgcgg gtcccgcccc ccacgtgcgc tgccgcctgg acatcaagcc agacgacgca
      841 gtgctccagc acgccacccg gggctcgcgg tcctgcgggc ccaccgaggc cgcgcactgg
      901 gcccgccccg ccccgcagtt ccacggcctc acggtgcccg ggccccgcca catggcgctg
      961 tcgcgcaccc cgacgcccag cgactcatac tgtgcggatc cccgggcgtt ctactgcgac
     1021 gggcccctgc ctgggccccg ggactacgcc gagcgccgca gtctgccctt caccaccccg
     1081 ccgggcccca cccagttctt ctatacagag gagccccaag gcttccgggg cagctttgca
     1141 gccagtcccg gcccaacctt cgacgcctac taccccaggc cctatccgtc cgaggagctc
     1201 tcggggccca gtccaaggcg catgggcggc tactacgcag gagaggtgcg caccttccca
     1261 atccaggaac cgccctcccg ctcctactat ggggaggctc cacgagccta cggcctgccc
     1321 tacgggcccc gctatgtccc cgaggagccc cgggcccact ccaccgcccg ccccttttac
     1381 acggaggact tcggaaggta ccgcgagcgt gacgtcctgg ctcggacgta cccgcacccg
     1441 cgcagcagcc cggcctgggc ggactggggc ccgcgaccgt accgcaccct gcaagtggtg
     1501 ccgccctctg accccgaccc gttgctcgcc tcctggcacg gcggcaccgg caccagtccg
     1561 ccccggctgg ccaccgacag ccgccactac tcgcgctcct gggacaacat tctggccccg
     1621 gggccgcgcc gagaagaccc gttgggccgc ggccgcagct acgagaacct gctggggcgc
     1681 gaggtgcggg agccgcgagg cgtgtccccc gaaggccggc gcccgcccgt cgtcgtgaac
     1741 ctgtccacct ctcccagacg ctacgccgca ctgtccctgt ccgagacgtc gctgacggag
     1801 aagggccgcg cgggcgaggg cctgggccgc aactggtacg tgacgcccga gatcaccatc
     1861 actgacaatg acctgcgcgc caccgagcgc ccgagcgcca gggcctggga gttgcccggg
     1921 ggccgcacgc ggccacctcc ccacgcggcc cccgacggcc ccacctctgg ccgccagcgg
     1981 agcctagagc agctggacga gctcatcacg gacctggtca tcgactcgcg acccaccgcc
     2041 ggccaggcct cagagcccgc ggccgactgc ctgggccccc aactgcgccg actgctggac
     2101 tcgcggcccg cgggctccgg ggcccccgcg ctggcgccgc cacgctcgcc ccccgcctcg
     2161 gccggcagcg ccgaggagcc cgcggccccg ggagaggcgg ccgacgcgtc ccccgaaccc
     2221 agcgccgacg aggacgacct gatgacctgc tccaatgcgc gctgccggcg caccgagacc
     2281 atgttcaacg cctgcctcta cttcaagtcc tgccacagct gctacaccta ctactgctcg
     2341 cgcctgtgcc gccgcgagga ctgggacgcc cacaaggcgc gctgcgtgta cggccgcgtg
     2401 ggcagcgtgt gccgccacgt actgcagttt tgccgcgaca gcggcccggt gcaccgcgct
     2461 ttctcgcgca tcgcgcgtgt cggcttcctg tcgcgcggcc gcggcgtgct cttcctgggc
     2521 ttcccaagtc caggctcggc cgacaacttc ctgcgctttg gcctggaggg gctgctgcta
     2581 tcccccacct acctatcgct gcgtgagctg gccacacacg cggcgcccct gggcagctac
     2641 gcgcgcgagc tggcggccgc tgggcgcctc tacgaaccgg cagagtgctt cctgctcagc
     2701 gtgtccgtgg ccgtgggacc cggcaccgcg ccaccgggga caccggccct gcccgcgccc
     2761 gcgccacgca gccacgggcc aacagtgcgc aagttcgcca aggtagcgct ggcggccggc
     2821 agccccgcgc ggccgccccc ggcgcggagc cgcgagcccg acatggagac gctgatcctg
     2881 acgccaccgc cgggcacggc gggcctggat caggacggcg aggcgggccg gcgcgcgcgc
     2941 gaggtggcct tcatccacat ccagcgcgag ctgcggctgc gcggcgtctt cctgcgccac
     3001 gagttcccgc gcgtctacga gcagctttgc gagttcgtcg aggccaacag gcgcttcacg
     3061 cccaccacca tctaccccac ggaccggcgc accggccgcc ccttcatgtg catgatcatg
     3121 gccgcctccg agccgcgcgc gctcgactgg gtggccagcg ccaacctgct ggacgacatc
     3181 atgtgaggcg ccgggcccac caggcctagc ccaggcgctg gcccgaaccc tgccctgccc
     3241 actcaggccc cgcccggccc acccagggcc gcccccgagc cccgccaggg ccccaccccg
     3301 acttcttcta ggccccgcct ctaattcccc agccttccaa gctccgctca gttcggcctc
     3361 cagctccgcc caggccccca ccccccggcc cttcgtcccc gtagtgttcc tcacaggccc
     3421 ttcgccttcc cacccccagc aacccctctc cctcctccgg gcctcctccc tctcccagct
     3481 cgccctcgag gatccccaga agaagtcggt cctcgccctc ggtgctcccc gctgggaggc
     3541 ggggtgggcc tgaggaccgc cgagctctgc cttcactcgg aggggtcact actgcacaga
     3601 ccccacccgt agagatccgg tccccgtcgg tccgcggggc tctcgctgga gcctccccga
     3661 ctccggtttc ccctcgtcca gaagcccgac gtaaccaaag cccagtctgt cactttaaac
     3721 acgccccgcc ccgcctcccg cggctgtgtt gcctcctcgc tggagaacac cctggtcgac
     3781 ctctgtgcgt ccgtgtgcgc gagcgcgtcc cgccgaggcg gtgggcaggg cggacggtgc
     3841 gcagtgcgtt cccgctggtc ggagccagca cactaaccac gccacgcgcc ctgccgtccc
     3901 ttcgcctcca gccgctgcag tctgggccct gcaggagctg ggaaaaaccg cagggaggtc
     3961 ttcaggccga tatgcaagtc tcccagccga aggggcaggg gacctgaaca ggggaagcag
     4021 agcacctggg cctggccaga gctgacacct ggctaggaga ggaaggacca agggacgggg
     4081 cgttcccagg tgggagcctg gagggcaaag cgtggtgcga gcaggtgagg gagagagcta
     4141 gttggtaagc gtggaagccc acccgagggg gcttgacctg tcccgagagg tccccgcaca
     4201 cccgctctgg ccgcacgccg tactgcgggc gtggaggcgc aagcccggcg gcccggcctc
     4261 cacctgtccc ccaagtgcac cctggtccgc gcccagagct ctctggaggg tggggtatgc
     4321 gggagagggg tggaggccaa acgcaagggc cctcctggag tccccagccc tacttcggag
     4381 ccaggggagg gggcaccaag tgagagaaat tgggcacccc cgcctccgct cctgctttcg
     4441 cacccggcac gcccatctcg tccccgcgcg tctgcaccgg ccaggcgtcc cgcttgccca
     4501 cccgccgccg cgccccgcgc cccctacccc agggcctctg cattcggccc cacccctgag
     4561 ggccggccgg gaacgcccct ggaccggaat aatttccagg gggcaagagc tttcgaacca
     4621 agtaaaatag aacttgaatg ta
//
