LOCUS       NM_138420              18335 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens AHNAK nucleoprotein 2 (AHNAK2), transcript variant 1,
            mRNA.
ACCESSION   NM_138420 XM_001132404 XM_290629
VERSION     NM_138420.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 18335)
  AUTHORS   Xu,M., Wen,J., Xu,Q., Li,H., Lin,B., Bhandari,A. and Qu,J.
  TITLE     AHNAK2 Promotes the Progression of Differentiated Thyroid Cancer
            through PI3K/AKT Signaling Pathway
  JOURNAL   Curr Cancer Drug Targets 24 (2), 220-229 (2024)
   PUBMED   36089788
  REMARK    GeneRIF: AHNAK2 Promotes the Progression of Differentiated Thyroid
            Cancer through PI3K/AKT Signaling Pathway.
REFERENCE   2  (bases 1 to 18335)
  AUTHORS   Li,X., Li,H., Shao,M.M., Miao,J., Fu,Y. and Hu,B.
  TITLE     Downregulation of AHNAK2 inhibits cell cycle of lung adenocarcinoma
            cells by interacting with RUVBL1
  JOURNAL   Thorac Cancer 14 (22), 2093-2104 (2023)
   PUBMED   37349884
  REMARK    GeneRIF: Downregulation of AHNAK2 inhibits cell cycle of lung
            adenocarcinoma cells by interacting with RUVBL1.
REFERENCE   3  (bases 1 to 18335)
  AUTHORS   Ye,R., Liu,D., Guan,H., AiErken,N., Fang,Z., Shi,Y., Zhang,Y. and
            Wang,S.
  TITLE     AHNAK2 promotes thyroid carcinoma progression by activating the
            NF-kappaB pathway
  JOURNAL   Life Sci 286, 120032 (2021)
   PUBMED   34627772
  REMARK    GeneRIF: AHNAK2 promotes thyroid carcinoma progression by
            activating the NF-kappaB pathway.
REFERENCE   4  (bases 1 to 18335)
  AUTHORS   Lin,Q.Y., Qi,Q.L., Hou,S., Chen,Z., Jiang,N., Zhang,L. and Lin,C.H.
  TITLE     Silencing of AHNAK2 restricts thyroid carcinoma progression by
            inhibiting the Wnt/beta-catenin pathway
  JOURNAL   Neoplasma 68 (5), 1063-1071 (2021)
   PUBMED   34374294
  REMARK    GeneRIF: Silencing of AHNAK2 restricts thyroid carcinoma
            progression by inhibiting the Wnt/beta-catenin pathway.
REFERENCE   5  (bases 1 to 18335)
  AUTHORS   Zheng,L., Li,S., Zheng,X., Guo,R. and Qu,W.
  TITLE     AHNAK2 is a novel prognostic marker and correlates with immune
            infiltration in papillary thyroid cancer: Evidence from integrated
            analysis
  JOURNAL   Int Immunopharmacol 90, 107185 (2021)
   PUBMED   33218938
  REMARK    GeneRIF: AHNAK2 is a novel prognostic marker and correlates with
            immune infiltration in papillary thyroid cancer: Evidence from
            integrated analysis.
REFERENCE   6  (bases 1 to 18335)
  AUTHORS   Han,H. and Kursula,P.
  TITLE     Periaxin and AHNAK nucleoprotein 2 form intertwined homodimers
            through domain swapping
  JOURNAL   J Biol Chem 289 (20), 14121-14131 (2014)
   PUBMED   24675079
  REMARK    GeneRIF: Periaxin and AHNAK nucleoprotein 2 form intertwined
            homodimers through domain swapping
REFERENCE   7  (bases 1 to 18335)
  AUTHORS   Okada,Y., Wu,D., Trynka,G., Raj,T., Terao,C., Ikari,K., Kochi,Y.,
            Ohmura,K., Suzuki,A., Yoshida,S., Graham,R.R., Manoharan,A.,
            Ortmann,W., Bhangale,T., Denny,J.C., Carroll,R.J., Eyler,A.E.,
            Greenberg,J.D., Kremer,J.M., Pappas,D.A., Jiang,L., Yin,J., Ye,L.,
            Su,D.F., Yang,J., Xie,G., Keystone,E., Westra,H.J., Esko,T.,
            Metspalu,A., Zhou,X., Gupta,N., Mirel,D., Stahl,E.A., Diogo,D.,
            Cui,J., Liao,K., Guo,M.H., Myouzen,K., Kawaguchi,T., Coenen,M.J.,
            van Riel,P.L., van de Laar,M.A., Guchelaar,H.J., Huizinga,T.W.,
            Dieude,P., Mariette,X., Bridges,S.L. Jr., Zhernakova,A., Toes,R.E.,
            Tak,P.P., Miceli-Richard,C., Bang,S.Y., Lee,H.S., Martin,J.,
            Gonzalez-Gay,M.A., Rodriguez-Rodriguez,L., Rantapaa-Dahlqvist,S.,
            Arlestig,L., Choi,H.K., Kamatani,Y., Galan,P., Lathrop,M., Eyre,S.,
            Bowes,J., Barton,A., de Vries,N., Moreland,L.W., Criswell,L.A.,
            Karlson,E.W., Taniguchi,A., Yamada,R., Kubo,M., Liu,J.S., Bae,S.C.,
            Worthington,J., Padyukov,L., Klareskog,L., Gregersen,P.K.,
            Raychaudhuri,S., Stranger,B.E., De Jager,P.L., Franke,L.,
            Visscher,P.M., Brown,M.A., Yamanaka,H., Mimori,T., Takahashi,A.,
            Xu,H., Behrens,T.W., Siminovitch,K.A., Momohara,S., Matsuda,F.,
            Yamamoto,K. and Plenge,R.M.
  CONSRTM   RACI consortium; GARNET consortium
  TITLE     Genetics of rheumatoid arthritis contributes to biology and drug
            discovery
  JOURNAL   Nature 506 (7488), 376-381 (2014)
   PUBMED   24390342
REFERENCE   8  (bases 1 to 18335)
  AUTHORS   de Morree,A., Droog,M., Grand Moursel,L., Bisschop,I.J.,
            Impagliazzo,A., Frants,R.R., Klooster,R. and van der Maarel,S.M.
  TITLE     Self-regulated alternative splicing at the AHNAK locus
  JOURNAL   FASEB J 26 (1), 93-103 (2012)
   PUBMED   21940993
REFERENCE   9  (bases 1 to 18335)
  AUTHORS   Huang,Y., Laval,S.H., van Remoortere,A., Baudier,J., Benaud,C.,
            Anderson,L.V., Straub,V., Deelder,A., Frants,R.R., den Dunnen,J.T.,
            Bushby,K. and van der Maarel,S.M.
  TITLE     AHNAK, a novel component of the dysferlin protein complex,
            redistributes to the cytoplasm with dysferlin during skeletal
            muscle regeneration
  JOURNAL   FASEB J 21 (3), 732-742 (2007)
   PUBMED   17185750
REFERENCE   10 (bases 1 to 18335)
  AUTHORS   Komuro,A., Masuda,Y., Kobayashi,K., Babbitt,R., Gunel,M.,
            Flavell,R.A. and Marchesi,V.T.
  TITLE     The AHNAKs are a class of giant propeller-like proteins that
            associate with calcium channel proteins of cardiomyocytes and other
            cells
  JOURNAL   Proc Natl Acad Sci U S A 101 (12), 4053-4058 (2004)
   PUBMED   15007166
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL512802.2.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_138420.3.
            
            Summary: This gene encodes a large nucleoprotein. The encoded
            protein has a tripartite domain structure with a relatively short
            N-terminus and a long C-terminus, separated by a large body of
            repeats. The N-terminal PSD-95/Discs-large/ZO-1 (PDZ)-like domain
            is thought to function in the formation of stable homodimers. The
            encoded protein may play a role in calcium signaling by associating
            with calcium channel proteins. Alternative splicing results in
            multiple transcript variants. [provided by RefSeq, Apr 2017].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based partly on alignments and guided by the published
            mouse sequence (PubMed ID 15007166).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2155984,
                              SAMEA2156670 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000333244.6/ ENSP00000353114.4
            RefSeq Select criteria    :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-192               AL512802.2         59490-59681         c
            193-251             AL512802.2         38921-38979         c
            252-350             AL512802.2         38717-38815         c
            351-452             AL512802.2         37895-37996         c
            453-603             AL512802.2         36790-36940         c
            604-788             AL512802.2         36264-36448         c
            789-18335           AL512802.2         18560-36106         c
FEATURES             Location/Qualifiers
     source          1..18335
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q32.33"
     gene            1..18335
                     /gene="AHNAK2"
                     /gene_synonym="C14orf78"
                     /note="AHNAK nucleoprotein 2"
                     /db_xref="GeneID:113146"
                     /db_xref="HGNC:HGNC:20125"
                     /db_xref="MIM:608570"
     exon            1..192
                     /gene="AHNAK2"
                     /gene_synonym="C14orf78"
                     /inference="alignment:Splign:2.1.0"
     CDS             138..17525
                     /gene="AHNAK2"
                     /gene_synonym="C14orf78"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein AHNAK2"
                     /codon_start=1
                     /product="protein AHNAK2 isoform 1"
                     /protein_id="NP_612429.2"
                     /db_xref="CCDS:CCDS45177.1"
                     /db_xref="GeneID:113146"
                     /db_xref="HGNC:HGNC:20125"
                     /db_xref="MIM:608570"
                     /translation="MCDCFHMVLPTWPGTPGSVSGRQLQPGEPGAETEDDHSVTEGPA
                     DEGIRPRPQGSSPVYEYTTEAADFGLQEDAPGRQGSAGRRRSWWKRDSGDSRTFFRMS
                     RPEAVQEATEVTLKTEVEAGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLL
                     STTVFFENIKYEDALKILQYSEPYKVQFKIRRQLPAPQDEEWASSDAQHGPQGKEKED
                     TDVADGCRETPTKTLEGDGDQERLISKPRVGRGRQSQRERLSWPKFQSIKSKRGPGPQ
                     RSHSSSEAYEPRDAHDVSPTSTDTEAQLTVERQEQKAGPGSQRRRKFLNLRFRTGSGQ
                     GPSSTGQPGRGFQSGVGRAGVLEELGPWGDSLEETGAATGSRREERAEQDREVMPAQS
                     MPLPTELGDPRLCEGTPQEGGLRAARLHGKTLEGQAQETAVAQRKPRAQPTPGMSREG
                     EGEGLQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVHDLKTPKFAFSTEKEPERERRL
                     STPQRGKRQDASSKAGTGLKGEEVEGAGWMPGREPTTHAEAQGDEGDGEEGLQRTRIT
                     EEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATEDTEQGREGEATATADRR
                     EQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQILTEKEVATKDSKFKMPKFKM
                     PLFGASAPGKSMEASVDVSAPKVEADVSLLSMQGDLKTTDLSVQTPSADLEVQDGQVD
                     VKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLSS
                     MEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMEDSV
                     DVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKV
                     HLPKVEMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDGEVSLPSMEVDVQAQK
                     AKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKALVDVSAPKVEA
                     DLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPS
                     FKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLDSARLE
                     GELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSLPSMQG
                     DLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLK
                     GPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKD
                     VTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDLSAPKVEADMSLPSMQGDLKTTDLSI
                     QPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGP
                     KLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFK
                     MPKFKMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLEV
                     QAGQVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKV
                     EVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSF
                     GVSAPGKSIEASVDVSEPKVEADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKL
                     PEGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKGPKLDLKGPKAEVMAPDVEV
                     SLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI
                     EASVDVSAPKVEAEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGA
                     GLKGHLPKVDMPSFKMPKVDLKGPQTDVKGAKLDLKGPKAEVTAPDVEVSLPSMEVDV
                     QAQKAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSIEASVDVPAP
                     KVEADVSLPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKV
                     EMPSLKMPKVDLKGPQVDIKGPKLDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDS
                     AHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSPPKVEADMSLP
                     SMQGDLKTTDLSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPK
                     VDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSL
                     ADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEASADVSALKVEADVSLPSMQGDLKTT
                     DLSVQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLKGPQID
                     VKGPKLDLKGPKTDVMAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTKD
                     SRFKIPKFKMPSFGVSAPGKSIEASVDVSAPKVEADGSLSSMQGDLKATDLSIQPPSA
                     DLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQLDVKGPKLDLK
                     GPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKFK
                     MPSFRVSAPGESIEALVDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQLEVQAGQV
                     DVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDLKGPKAEVTAP
                     DVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAP
                     GKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVKLPEGHV
                     PEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVEVSLPSV
                     EVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVSVD
                     VSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGH
                     LPKLQMPSFKMPKVDRKGPQIDVKGPKLDLKGPKTDVTAPDVEVSQPGMEVDVEAPGA
                     KLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVLVDVSAPKVEAD
                     LSLPSMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSF
                     KMPKVDRKGPQIDIKGPKLDLKGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEG
                     DLSLADKDVTAKDSKFKMPKFKMPSYRASAPGKSIQASVDVSAPKAEADVSLPSMQGD
                     LKTTDLSIQLPSVDLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKS
                     PQVDIKGPKLDLKVPKAEVTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDV
                     TAKDSKFKMPKFKMPSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQ
                     PPSADLEVQAVQVDVELLEGPVPEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPK
                     LDLKGPKAEVRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKM
                     PKFKMPSFRVSAPGKSMEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQ
                     AGQMDVKLPEGQVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKAE
                     VTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFG
                     VSAPGKSIEASVHVSAPKVEADVSLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKLL
                     EGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVS
                     LPSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSME
                     ASVDVTAPKVEADVSLPSMQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAS
                     LKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVKMSLSSMEVDVQ
                     APRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVSELK
                     AKADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQ
                     MPCLKMPKVALKGPQVDVKGPKLDLKGPKADVMTPVVEVSLPSMEVDVEAPGAKLDSV
                     RLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSIEASLDVSALKVEADVSLPS
                     MQGDLKTTHLSIQPPSADLEVQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPSFKVPKV
                     DLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLSLA
                     DKDVTAKDSKFKMPKFKMPSFGMLSPGKSIEVSVDVSAPKMEADMSIPSMQGDLKTTD
                     LRIQAPSADLEVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVDLKGPQVDV
                     KGPKLDLKGPKAEVMAPDVEVSLPSVETDVQAPGSMLDGARLEGDLSLAHEDVAGKDS
                     KFQGPKLSTSGFEWSSKKVSMSSSEIEGNVTFHEKTSTFPIVESVVHEGDLHDPSRDG
                     NLGLAVGEVGMDSKFKKLHFKVPKVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSECS
                     SFELQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPHFESSILSPCEDVTLTKYQVTVP
                     RAALAPELALEIPSGSQADIPLPKTECSTDLQPPEGVPTSQAESHSGPLNSMIPVSLG
                     QVSFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVMSPLSPGERVQCPLPSTQLPSPGT
                     CVSQGPEELVASLQTSVVAPGEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPK
                     VDPECSVEDSKLSLVLDKDEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMK
                     ASKSGVSLPQRDVDPSLSSATAGGSFQDTEKASSDGGRGGLGATASATGSEGVNLHRP
                     QVHIPSLGFAKPDLRSSKAKVEVSQPEADLPLPKHDLSTEGDSRGCGLGDVPVSQPCG
                     EGIAPTPEDPLQPSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRD
                     RGGAGKLEVAQTQAPAATGGEAAAKVKEFLVSGSNVEAAMSLQLPEADAEVTASESKS
                     STDILRCDLDSTGLKLHLSTAGMTGDELSTSEVRIHPSKGPLPFQMPGMRLPETQVLP
                     GEIDETPLSKPGHDLASMEDKTEKWSSQPEGPLKLKASSTDMPSQISVVNVDQLWEDS
                     VLTVKFPKLMVPRFSFPAPSSEDDVFIPTVREVQCPEANIDTALCKESPGLWGASILK
                     AGAGVPGEQPVDLNLPLEAPPISKVRVHIQGAQVESQEVTIHSIVTPEFVDLSVPRTF
                     STQIVRESEIPTSEIQTPSYGFSLLKVKIPEPHTQARVYTTMTQHSRTQEGTEEAPIQ
                     ATPGVDSISGDLQPDTGEPFEMISSSVNVLGQQTLTFEVPSGHQLADSCSDEEPAEIL
                     EFPPDDSQEATTPLADEGRAPKDKPESKKSGLLWFWLPNIGFSSSVDETGVDSKNDVQ
                     RSAPIQTQPEARPEAELPKKQEKAGWFRFPKLGFSSSPTKKSKSTEDGAELEEQKLQE
                     ETITFFDARESFSPEEKEEGELIGPVGTGLDSRVMVTSAARTELILPEQDRKADDESK
                     GSGLGPNEG"
     exon            193..251
                     /gene="AHNAK2"
                     /gene_synonym="C14orf78"
                     /inference="alignment:Splign:2.1.0"
     exon            252..350
                     /gene="AHNAK2"
                     /gene_synonym="C14orf78"
                     /inference="alignment:Splign:2.1.0"
     exon            351..452
                     /gene="AHNAK2"
                     /gene_synonym="C14orf78"
                     /inference="alignment:Splign:2.1.0"
     exon            453..603
                     /gene="AHNAK2"
                     /gene_synonym="C14orf78"
                     /inference="alignment:Splign:2.1.0"
     exon            604..788
                     /gene="AHNAK2"
                     /gene_synonym="C14orf78"
                     /inference="alignment:Splign:2.1.0"
     exon            789..18335
                     /gene="AHNAK2"
                     /gene_synonym="C14orf78"
                     /inference="alignment:Splign:2.1.0"
     regulatory      18313..18318
                     /regulatory_class="polyA_signal_sequence"
                     /gene="AHNAK2"
                     /gene_synonym="C14orf78"
                     /note="hexamer: AATAAA"
     polyA_site      18335
                     /gene="AHNAK2"
                     /gene_synonym="C14orf78"
                     /note="major polyA site"
ORIGIN      
        1 agtccgaggt cggccgcccg cggcagcgca gggcagcggg gcagagcgcg gctcccgccc
       61 gcccgccccg tgcgccggag ccgggaccag cgactggacg cgacgggccg ccaggcccgc
      121 accgcctggc cgccgcgatg tgcgactgct tccacatggt gctgcccacc tggcccggaa
      181 cccccggcag cgtgtccggc cgtcagctgc agcccgggga gccaggtgca gaaacggaag
      241 atgaccactc tgtgactgaa gggcctgcgg atgagggcat tcgaccacgg ccgcaggggt
      301 cttcacctgt ctacgaatac acgactgagg ctgccgactt tggactccag gaagacgccc
      361 ccggcaggca aggttctgct gggagacgga gatcctggtg gaagcgagat tcaggggact
      421 cacggacatt tttcaggatg agtcgtccag aggctgtcca ggaggcaaca gaggtgacgc
      481 tgaagacaga ggtggaggca ggagccagtg gctacagtgt cacaggtggt ggggaccagg
      541 ggatcttcgt caagcaagtg ctgaaggact cctcagccgc caagcttttt aacttgagag
      601 aaggggatca gctgctcagt acaaccgtgt tctttgaaaa cataaaatat gaagatgctc
      661 tcaaaatcct tcaatattca gagccgtaca aggttcagtt caaaatcaga cggcagctcc
      721 ctgccccaca ggatgaagag tgggcttcca gcgatgccca gcacggccca cagggcaagg
      781 agaaggagga cacggatgtt gctgatgggt gcagagagac ccccacgaaa actctggaag
      841 gagatgggga ccaagagaga ctcatctcca aaccaagggt ggggagaggc aggcagagcc
      901 agagggagag gctctcttgg ccaaaatttc aatccataaa gagcaagcgg gggccgggac
      961 cccagaggtc acacagctcg tcagaggcct acgaacctag ggacgcacat gacgtgtccc
     1021 ctacaagcac agacacagag gcccagctca cggtggagcg ccaagagcag aaggcagggc
     1081 cgggcagcca gaggaggcgg aagttcctca acctcagatt caggacaggc tcgggacagg
     1141 gcccttcatc gacaggacag ccaggcaggg ggttccagag tggggtgggc cgtgctgggg
     1201 tcctggaaga gttggggccc tggggtgata gcctcgagga gactggggct gccacaggca
     1261 gcaggagaga ggagagggca gaacaggatc gagaagtgat gcctgctcag agcatgccat
     1321 tgcccacaga gctcggtgac cctagacttt gcgagggaac ccctcaggaa gggggactca
     1381 gggcagccag gctccatgga aagaccctgg aggggcaggc acaggagaca gcagtggccc
     1441 agaggaagcc cagggcccag ccaactcctg gaatgagccg ggagggtgaa ggcgagggac
     1501 tgcagagcct ggaaatcggg atcgccagac tgtccttgag agacacaacc gaaggaggca
     1561 cacagattgg cccaccagaa attagggtgc gagtacacga tttaaagaca ccaaaatttg
     1621 cattttccac agaaaaagag ccagaaagag aaaggcgcct tagtacccca cagcgaggga
     1681 agagacagga tgcgtcctca aaagcgggta ctggcctgaa gggtgaggag gtggaaggag
     1741 ccgggtggat gccgggcagg gaaccaacca cacatgcaga agcacagggg gatgaaggag
     1801 atggagagga aggactacag aggacaagga tcactgagga acaggacaag ggcagggaag
     1861 acacagaagg acagataaga atgcccaagt tcaagatacc ctccttagga tggtcgccaa
     1921 gcaagcacac aaagacaggc agagaaaaag ccacagaaga cacagagcag ggaagggaag
     1981 gagaggccac agcaacagct gatagaagag aacagagacg cacagaggaa ggattaaaag
     2041 acaaagaaga cagtgactca atgacaaaca caacaaaaat acaactaata cacgatgaaa
     2101 aacgcttaaa aaaggaacaa attctgacag aaaaggaagt ggccaccaaa gacagcaagt
     2161 tcaaaatgcc caagttcaag atgccattgt tcggggcgtc agccccaggc aagtccatgg
     2221 aggcctcggt ggatgtgtct gcgccgaagg tggaggccga cgtgagcctc ctctccatgc
     2281 agggggacct caagaccact gacctcagcg tccagacccc ttccgctgac ctggaggtcc
     2341 aggatggcca agtggatgtg aaacttccgg agggccccct gcccgaggga gccagcctca
     2401 aagggcacct gcccaaggtg cagaggccca gtttgaagat gcccaaagtg gacctcaagg
     2461 gccccaagct ggacctgaaa ggccccaagg cggaagtgac agcccccgat gtgaagatgt
     2521 ctctgtccag catggaggtg gacgtccagg ccccgagagc aaagctggat ggtgcgcggc
     2581 tggaggggga cctgtccctg gccgacaagg aggtgactgc caaagacagc aagttcaaaa
     2641 tgcccaagtt caagatgcca tcattcgggg tgtcggcccc aggcaagtcc atggaggact
     2701 cggtggatgt gtctgcgccg aaggtggagg ccgacgtgag cctctcctcc atgcaggggg
     2761 acctcaaggc cactgacctc agcattcagc ccccttccgc tgacctggag gtccaggctg
     2821 gccaagtgga tgtgaaactt ccggagggcc ctgtgcccga gggagccggc cccaaagtgc
     2881 acctgcccaa agtggagatg cccagtttca agatgcccaa agtggacctc aagggccccc
     2941 agatagatgt taagggcccc aagctggacc tgaaaggccc caaggcggaa gtgacagccc
     3001 ccgatggcga ggtgtctctg cccagcatgg aggtggatgt ccaggcccag aaggccaagc
     3061 tggatggtgc gtggctggag ggggacctgt ccctggccga caaggacgtg actgccaaag
     3121 acagcaagtt caaaatgccc aagttcaaga tgccgtcgtt cggggtatcg gccccaggga
     3181 agtccatcaa ggccttggtg gatgtgtctg cacccaaggt ggaggccgac ctgagtctcc
     3241 cctccatgca gggggacctg aagaccactg acctcagcat tcagcctgct tctactgacc
     3301 tgaaggtcca ggctgaccag gtggatgtga agctcccgga gggccacctg cccgagggag
     3361 ctggccttaa agggcacttg cccaaggtgg agatgcccag tttcaagatg cccaaagtgg
     3421 ccctcaaggg cccccaggtg gacgtcaagg gccccaagct ggacctgaaa agccccaagg
     3481 cggaagtcac agcccctgat gtggaggtgt ctctgcccag cgtggaggtg gacgtcgagg
     3541 ccccgggagc caagctggac agtgcgcggc tggaggggga actgtccctg gccgacaagg
     3601 atgtgactgc caaagacagc aggttcaaaa tgcccaagtt caagatgcca tcgttcgggg
     3661 cgtcagcccc aggcaagtcc atcgaggcct cggtggatgt gtctgcaccc aaagtggagg
     3721 ccgacgtgag tctcccctcc atgcaggggg acctcaagac cactgacctc agcattcagc
     3781 ccccttccgc tgacctggag gtccacgctg gccaggtgga cgtgaagctc ctggagggcc
     3841 acgtgcctga gggagccggc ttcaaagggc acctgcccaa ggtgcagatg cctagtttga
     3901 agatgcccaa agtggacctc aagggccccc aggtggaagt caggggcccc aagctggacc
     3961 tgaaaggtca taaggcagag gtgacggccc acgaagtggc tgtgtctctg cccagtgtgg
     4021 aggtggacat gcaggccccg ggagccaagt tggatggcgc acagctggac ggggacctgt
     4081 ccctggctga caaggacgtg actgccaaag acagcaagtt caaaatgccc aagttcaaga
     4141 tgccgtcgtt cggggtgtct gccccaggca agtccattga ggcctccgtg gacctgtctg
     4201 cacccaaggt ggaggccgac atgagcctcc cctccatgca gggggacctc aagaccactg
     4261 acctcagcat tcagccccct tccactgacc tggagctcca ggctggccaa ttggacgtga
     4321 aactcccaga gggccccgtg cccgagggag ccggcctcaa agggcacctg cccaagctgc
     4381 agatgcccag tttcaaggtg cccaaagtgg acctcaaggg ccctgaaata gacatcaagg
     4441 gccccaagct ggacctaaaa gaccccaagg tggaagtgac agcccctgat gtggaggttt
     4501 ctctgcccag cgtggaggtg gatgtcgagg ccccaggagc caagctggat ggtggacggc
     4561 tggaggagga catgtccctg gccgacaagg acttgactac caaagacagc aagttcaaaa
     4621 tgcccaagtt caagatgccg tcgttcgggg tgtctgcccc aggcaagtcc atcgaggcct
     4681 cagtggatgt gtctgcgccg aaggtggagg ccgacgtgag cctcccctcc atgcaggggg
     4741 acctcaaggc cactgacctg agcatacagc ccccttctgc tgacctggag gtccaggctg
     4801 gccaagtgga cgtgaaactc ccagagggcc ctgtgtccga gggagccggc ctcaaagggc
     4861 acctgcccaa agtgcagatg cccagtttca agatgcccaa agtggacctc aaggggcccc
     4921 agatagatgt taagggcccc aagctggacc tgaaaggccc caaggtggaa gtgacagccc
     4981 ccgatgtgaa gatgtctctg tccagcatgg aggtggacgt ccaggccccg agagcaaagc
     5041 tggatggtgc gcagctggag ggggacctgt ccctggccga caaggcggtg actgccaaag
     5101 acagcaagtt caaaatgccc aagttcaaga tgccatcatt tggggtgtcg gccccaggca
     5161 agtccatcga ggcctcggtg gatgtgtctg agccgaaggt ggaagctgat gtgagcctcc
     5221 cctccatgca gggggacctg aagaccactg acctcagcat tcagtcccct tccgccgacc
     5281 tggaggtcca ggctggccaa gtgaacgtga aactcccgga gggccccctt cccgagggag
     5341 ccggcttcaa agggcacctc cccaaggtgc agatgcccag tttgaagatg cccaaagtgg
     5401 ccctcaaggg cccccagatg gacgtcaagg gccccaagct ggacctgaaa ggccccaagg
     5461 cggaggtgat ggcccccgac gtggaggtgt ctctgcccag cgtggaggtg gacgtcgagg
     5521 ctccaggagc caagctggac agtgtgcggc tggagggtga cctgtccctg gccgacaagg
     5581 atgtgactgc caaagacagc aagttcaaaa tgcccaagtt caagatgccg tcgttcgggg
     5641 tgtctgcccc aggcaagtcc atcgaggcct cggtggatgt gtctgcgccg aaggtggagg
     5701 ccgaagtgag cctcccctcc atgcaggggg acctcaagac cacggacctc tgcattccgc
     5761 tcccttctgc agacctggtg gtccaggctg gccaagtgga catgaagctc ccggagggcc
     5821 aggtgcccga gggagccggc ctcaaagggc acttgcccaa ggtggatatg cccagtttca
     5881 agatgcccaa agtggacctc aagggccccc agacagatgt taagggcgcc aagctggacc
     5941 tgaaaggccc caaggcggaa gtgacagccc ccgatgtcga ggtgtctctg cccagcatgg
     6001 aggtggatgt ccaggcccag aaggctaagc tggatggtgc gcggctggag ggagacctgt
     6061 ccctggccga caaggacatg actgccaaag acagcaagtt caaaatgccc aaattcaaga
     6121 tgccgtcgtt cggggtatcg gccccaggga ggtccatcga ggcctcggtg gatgtgcctg
     6181 cacccaaggt ggaggccgac gtgagtctcc cctccatgca gggggacctg aagaccactg
     6241 acctcagcat tcagccccct tctgccgacc tgaaggtcca gactggccag gtggatgtga
     6301 agctcccgga gggccacgtg cccgagggag ctggcctcaa agggcacctg cccaaggtgg
     6361 agatgcccag tttgaagatg cccaaagtgg acctcaaggg cccccaggtg gacatcaagg
     6421 gccccaaact ggacctaaaa gaccccaagg tggaaatgag agtccccgat gtcgaggtgt
     6481 ctctgcccag catggaggtg gacgtccagg ccccaagagc caagctggat agtgcgcatc
     6541 tgcaggggga cctgaccctg gccaacaagg acctgactac caaagacagc aagttcaaaa
     6601 tgcccaagtt caagatgccg tcgtttgggg tgtctgcccc aggcaagtcc atcgaggcct
     6661 cggtggatgt gtctccaccc aaggtggagg ccgacatgag tctcccctcc atgcaggggg
     6721 acctcaagac cactgacctc agcattcagc ccctttccgc cgacgtgaag gtccaggctg
     6781 gccaggtgga cgtgaaactc ctggagggcc ctgtgcccga ggaagtcggc ctcaaagggc
     6841 acctgcccaa gctgcagatg cccagtttca aggtgcccaa agtggacctc aagggccccg
     6901 aaatagacat caagggcccc aagctggacc taaaagaccc caaggtggaa gtgacagccc
     6961 ctgatgtgga ggtgtctctg cccagcgtgg aggtggacgt caaggcccca ggagccaagc
     7021 tggatggtgc gcggctggag ggggacatgt ccctggccga caaggacgtg actgccaaag
     7081 acagcaagtt caaaatgccc aagttcaaga tgctgtcgtt tggggtgtct gcccttggca
     7141 agtccatcga ggcctcagcg gatgtgtctg cgttgaaggt ggaggccgac gtgagcctcc
     7201 cctccatgca gggggacctc aagaccactg acctcagcgt tcagccccct tccgctgacc
     7261 tggaggtcca ggctggccaa gtggatgtga aactcccaga gggccccgtg ccggagggag
     7321 ccggcctcaa agggcacctg cccaagctgc agatgcccag tttcaagatg cccaaagtag
     7381 atctcaaggg cccccagata gatgtcaagg gccccaagct ggacctgaaa ggccccaaga
     7441 cggacgtgat ggcccccgac gtggaggtgt ctcagcccag cgtggaggtg gatgtcgagg
     7501 ccccgggagc caagctggat ggtgcgtggc tggaggggga cctgtctgtg gcggacaagg
     7561 atgtgactac caaagacagc aggttcaaaa ttcccaagtt caagatgccg tcattcgggg
     7621 tgtctgcccc aggcaagtcc atcgaggcct cggtggatgt gtctgcgccg aaggtggagg
     7681 ccgacgggag cctctcctcc atgcaggggg acctcaaggc cactgacctc agcattcagc
     7741 ccccttccgc tgacctggag gtccaggctg gccaagtgga cgtgaaactc ccagagggcc
     7801 ctgtgccgga gggagccggc ctcaaagggc acctgcccaa ggtgcagatg cccagtttca
     7861 agatgcctga aatggacctc aagggccccc agctagatgt caagggcccc aagctggacc
     7921 tgaaaggccc caaggcggaa gtgacagccc ccgatgtgga gatgtctctg tccagcatgg
     7981 aggtggacgt ccaggccccg agagcaaagc tggatggtgc gcggctggag ggggacctgt
     8041 ccctggccga caagggtgtg acagccaaag atagcaagtt caaaatgccc aagttcaaga
     8101 tgccatcatt cagggtgtcg gccccaggcg agtccatcga ggcgttggtg gatgtgtctg
     8161 agctgaaggt ggaagccgac atgagcctcc cctccatgca aggggacctt aagaccactg
     8221 acatcagcat tcagcccccc tctgcccaac tggaggtcca ggctggccag gtggatgtga
     8281 aactcccaga gggccacgtt cccgagggag ccggcctcaa agggcacctg cccaagctgc
     8341 agatgcccag tttcaagatg cctgaagtgg acctcaaggg cccccagata gatgttaagg
     8401 gccccaacgt ggacctgaaa ggccccaagg cggaagtgac agcccccgat gtgaagatgt
     8461 ctctgtccag catggaggtg gacgtccagg ccccgagagc aaagctggat ggtgcgcggc
     8521 tggaggggga cctgtccctg gccgacaagg gcatgacagc caaagacagc aagttcaaaa
     8581 tgcccaagtt caagatgccg tcattcgggg tgtcggcccc aggcaagtcc atcgaggcct
     8641 cggtggatgt gtctgagctg aaggtggaag ctgacgggag cttcccctcc atgcaagggg
     8701 atcttaagac cactgacatc cgcattcagc ccccctccgc ccaactggag gtccaggctg
     8761 gccaggtgga cgtgaaactc ccagagggcc acgttcccga gggagccggc ctcaaagggc
     8821 acctgcccaa ggtgcagatg cccagtttca agatgcccaa agtggatctc aagggccccc
     8881 agatagacgt caagggcccc aagctggacc tgaaaggccc caaggcggag gtgacggccc
     8941 ccgacgtgga ggtgtctctg cccagcgtgg aggtggacgt cgaggccccg agagcaaagc
     9001 tggatggtgc acggctggag ggtgacctgt ccctggccga caaggatgtg actgccaaag
     9061 acagcaagtt caaaatgccc aagttcaaga tgccgtcgtt cggggtgtct gccccaggca
     9121 agtccattga ggtctcggtg gatgtgtctg cgccgaaggt ggaggccgaa gtgagcctcc
     9181 cctccatgca gggggacctg aagaccactg acatcagcat tgagcccccc tctgcccaac
     9241 tggaggtcca ggctggccag gtggacctga agctcccaga gggccacgtt cccgagggag
     9301 ctggcctcaa agggcacctg cccaagttgc agatgcccag tttcaagatg cccaaagtag
     9361 atcgcaaggg accccagata gatgtcaagg gccccaagct ggacctgaaa ggcccgaaga
     9421 cggacgtgac ggcccccgac gtggaggtgt ctcagcccgg catggaggtg gatgtcgagg
     9481 ccccaggagc caagttggat ggtgcacggc tggaggggga cctgtccctg gccgacaagg
     9541 atgtgactgc caaagacagc aagttcaaaa tgcccaagtt caagatgccg tcgttcgggg
     9601 tgtctgcccc aggcaagtcc attgaggtct tggtggatgt gtctgcgcca aaggtggagg
     9661 ccgacctgag cctcccctcc atgcaggggg acctgaagaa cactgacatc agcattgagc
     9721 ccccctctgc ccaactggag gtccaggctg gccaggtgga cgtgaagctc ccagagggcc
     9781 acgttctcga gggagctggc ctcaaagggc acctgcccaa gttgcagatg cccagtttca
     9841 agatgcccaa agtagatcgc aagggccccc agatagacat caagggcccc aagctggacc
     9901 tgaaaggccc gaagatggat gtgacggccc ccgacgtgga ggtgtctcag cccagcatgg
     9961 aggtggacgt cgaggcccca ggagccaagt tggatggtgc acggctggag ggggacctgt
    10021 ccctggccga caaggatgtg actgccaaag acagcaagtt caaaatgccc aaattcaaga
    10081 tgccgtcgta cagggcgtct gccccaggca agtccatcca ggcctcggtg gatgtgtctg
    10141 cgccgaaggc ggaggccgac gtgagcctcc cctccatgca gggggacctc aagaccactg
    10201 acctcagcat tcagctccct tctgtggacc tggaggtcca ggctggccag gtggacgtga
    10261 agctcccgga gggccacgtg cccgagggag ctggcctcaa agggcacctg cccaaggtgg
    10321 agatgcccag tttcaagatg cccaaagtgg acctcaagag cccccaggtg gacatcaagg
    10381 gccccaagct ggacctaaaa gtccccaagg cggaagtgac agtccctgat gtggaggtgt
    10441 ctctgcccag cgtggaggtg gacgtccagg ccccgagagc caagctggat ggtgcgcggc
    10501 tggaggggga cctgtccctg gctgaaaagg atgtgactgc caaagacagc aagttcaaaa
    10561 tgcccaagtt caagatgccc tccttcgggg tgtcggcccc aggcaggtcc atcgaggcct
    10621 cgctggatgt gtctgcgccg aaggtggagg ccgacgtgag cctctcctcc atgcaggggg
    10681 acctcaaggc cactgacctc agcattcagc ccccttccgc tgacctggag gtccaggctg
    10741 tccaagtgga tgtggaactc ctggagggcc ccgtgcccga gggagccggc ctcaaagggc
    10801 acctgcccaa agtggagatg cccagtttaa agacgcccaa agtggacctc aagggccccc
    10861 agatagatgt taagggcccc aagctggacc tgaaaggccc caaggcagaa gtgagagtcc
    10921 ccgatgtcga ggtgtctctg cccagcgtgg aggtggatgt ccaggccccg aaggccaagc
    10981 tggatgctgg gcggctggag ggagacctgt ccctggctga caaggacgtg actgccaaag
    11041 acagcaagtt caaaatgccc aaattcaaga tgccgtcatt cagggtatcg gccccaggga
    11101 agtccatgga ggcctcggtg gatgtgtctg cacccaaggt ggaagccgat gtgagtctcc
    11161 cctccatgca gggggacctg aagaccactg acctcagcat tcagccccct tctgccgacc
    11221 tgaaggtcca ggctggccag atggatgtga agctcccgga gggccaggtg cccgagggag
    11281 ccggcctcaa agagcacctg cccaaggtgg agatgcccag tttgaagatg cccaaagtgg
    11341 acctcaaggg cccccaggtg gacatcaagg gccccaagct ggacctaaaa gtctccaagg
    11401 cggaagtcac agcccctgat gtggaggtgt ctctgcccag cgtggaggtg gacgtccagg
    11461 ccccaagagc caaactggat agtgcacagc tggaggggga cctgtccctg gccgacaagg
    11521 atgtgactgc caaagacagc aaattcaaaa tgcccaagtt caagatgccg tcatttgggg
    11581 tgtctgcccc aggcaagtcc attgaggcct cggtgcacgt gtctgcaccc aaggtggagg
    11641 ccgatgtgag tctcccctcc atgcaggggg acctcaagac cactgacctc agcattcagc
    11701 cccattctgc cgacctgacg gtccaagctc gccaggtgga catgaaactc ctggagggcc
    11761 acgtgcccga ggaagccggc ctcaaaggac acctgcccaa ggtgcagatg cccagtttca
    11821 agatgcccaa agtcgacctc aagggccctg aaatagacat caagggcccc aagctggacc
    11881 taaaagaccc caaggtggaa gtgacagccc ctgatgtgga ggtttctctg cccagcgtgg
    11941 aggtggacgt cgaggcccca ggagccaagc tggatggtgc gcggctggag ggggacctgt
    12001 ccctggccga caaggacatg acggccaaag acagcaagtt caaaatgccc aagttcaaga
    12061 tgccgtcgtt cggggtgtct gccccaggca agtccatgga ggcatcagtg gatgtgaccg
    12121 cgccaaaggt ggaggccgac gtgagcctcc cttccatgca gggggacctc aaggccactg
    12181 acctcagcgt tcagccccct tccgctgacc tggaggtcca ggctggccaa gtggacgtga
    12241 aactcccaga gggccccgtg cccgagggag ccagcctcaa agggcacctg cccaaggtgc
    12301 agatgcccag tttcaagatg cccaaagtgg acctcaaggg cccccagata gatgttaagg
    12361 gccccaagct ggacctgaaa ggccccaagg cggaagtgac agcccctgat gtgaagatgt
    12421 ctctgtccag catggaggtg gacgtccagg ccccgagagc aaagctggat ggtgtgcagc
    12481 tggaggggga cctgtccctg gccgacaagg atgtgactgc caaagacagc aagttcaaaa
    12541 tgcccaagtt caagatgcca tcattcgggg tgtcggcccc aggcaagtcc atggaggcgt
    12601 ccgtggatgt gtctgagctg aaggcgaaag ccgacgtgag cctcccctcc atgcaggggg
    12661 acctcaagac cactgacctc agcattcagt ccccttccgc cgacctggag gtccaggctg
    12721 gccaagtgga cgtgaaactc ccggagggcc ccctgcccaa gggagccggc ctcaaagggc
    12781 acctccccaa ggtgcagatg ccctgtttga agatgcccaa agtggccctc aagggccccc
    12841 aggtggatgt caagggcccc aagctggacc tgaaaggccc caaggcggat gtgatgaccc
    12901 ccgtcgtgga ggtgtctctg cccagcatgg aggtggacgt cgaggccccg ggagccaagc
    12961 tggacagtgt gcggctggag ggtgacctgt ccctagccga caaggacatg actgccaaag
    13021 acagcaagtt caaaatgccc aagttcaaga tgccgtcgtt cggggtgtct gccccaggca
    13081 agtccatcga ggcctcgttg gatgtgtctg cgctgaaggt ggaggctgac gtgagcctcc
    13141 cctccatgca gggggacctg aagaccactc acctcagcat tcagccccct tccgctgatc
    13201 tggaggtcca ggctggccaa gaggatgtga aactcccaga gggccctgtg catgagggag
    13261 ccggcctcaa agggcacctg ccgaagctgc agatgcccag tttcaaggta cccaaagtgg
    13321 acctcaaggg tccccagata gacgttaatg tccccaagct ggacctgaaa ggccccaagg
    13381 tggaggtgac gtcccccaac ctggacgtgt ctctgcccag catggaggtg gacatccaag
    13441 ccccaggagc caagctggac agtacgcggc tggaggggga cctgtccctg gctgacaagg
    13501 acgtgactgc caaagacagc aagttcaaaa tgcccaagtt caagatgcca tcctttggga
    13561 tgttgtcccc aggcaagtcc atcgaggtct cggtggatgt gtctgcgcca aagatggagg
    13621 ccgacatgag cattccctcc atgcaggggg acctcaagac cactgacctc cgcattcagg
    13681 ccccttccgc cgacctggag gtccaggctg gccaggtgga cttgaaactt ccagaaggcc
    13741 acatgcccga ggtagccggc ctcaaagggc acctgcccaa ggtggagatg cccagtttca
    13801 agatgcccaa agtggacctc aagggccccc aggtggacgt caagggcccc aagctggacc
    13861 tgaaaggccc aaaggcagag gtgatggccc ccgatgtgga ggtgtctctg cccagcgtgg
    13921 agacggatgt ccaggcccca ggatccatgc tggatggtgc gcggcttgag ggggacctgt
    13981 ccctggccca cgaggatgta gctgggaaag acagtaagtt tcaaggacca aaactgagca
    14041 cgtctggttt tgaatggtcg tcaaagaaag tttccatgtc ttcctctgaa atcgaaggaa
    14101 atgttacatt ccatgagaag acttccacat ttcccattgt ggaatctgtt gttcatgaag
    14161 gtgatcttca tgatccatct cgcgatggta acttggggct tgctgttgga gaagttggaa
    14221 tggattcgaa gtttaagaaa ctgcatttta aagtgcccaa agtttcattt tcttctacca
    14281 aaactcctaa agatagttta gtcccaggtg caaagtctag cataggtctt tccacgattc
    14341 ctttatcatc ttcagaatgc tcaagttttg aattacaaca ggtttcggct tgttcagagc
    14401 catccatgca gatgcctaag gtgggttttg ctgggtttcc atcatcccgg cttgatctca
    14461 ctggtcctca ctttgaatct tctattctct ctccctgtga ggatgttaca cttacaaaat
    14521 accaggtgac tgttcccaga gctgccttgg cccctgagct tgctctggaa attccttctg
    14581 ggtctcaggc tgatattcct cttcccaaga cagagtgctc cactgacctg cagcctccag
    14641 agggagttcc aacatctcaa gctgagagtc actctggccc actgaattcc atgattcctg
    14701 tttctcttgg tcaggtatct tttcctaaat tctataaacc aaagtttgtg ttttcagtcc
    14761 cccaaatggc agttcctgag ggagacctac atgcagcagt gggtgcccca gtcatgtctc
    14821 ctcttagccc tggagaaaga gtgcagtgcc ccttgccaag cacccagctg ccatccccag
    14881 gcacctgtgt gtctcagggc ccagaagagc ttgtggcctc cttgcagaca tcagtagtgg
    14941 cccctggaga agccccttct gaagatgctg accacgaagg gaaagggagt cccttgaaaa
    15001 tgcctaagat taagcttcca tcatttaggt ggtccccgaa gaaggaaaca gggccaaagg
    15061 tggacccaga atgcagcgtg gaggactcaa aactcagcct ggttttagac aaggatgaag
    15121 tggccccgca gtctgccatc cacatggatc tgcctcctga gagggatgga gagaagggga
    15181 ggagcacaaa gcctggcttt gccatgccaa aacttgcact tcccaaaatg aaggcttcta
    15241 agagtggggt cagcctgcca cagagagacg tggatccttc cctttctagt gccacagcag
    15301 ggggtagctt tcaagacaca gaaaaggcca gcagtgacgg tggtagggga ggacttggtg
    15361 caacagcaag tgccacagga agtgagggtg tgaacctcca ccggccacag gtccacattc
    15421 ccagtttggg ctttgccaaa cctgatctca gatcctccaa ggccaaggtg gaggtgagcc
    15481 agcctgaagc tgacctgcct cttcccaaac atgatctgtc taccgaaggt gacagcagag
    15541 gatgtgggct cggggatgtc ccagtgagcc agccttgtgg ggaggggata gcccccacac
    15601 ctgaagatcc cctccagcca tcctgtagaa aaccagatgc tgaagtcctc acagtggaaa
    15661 gcccagagga ggaagccatg accaagtact cgcaggaaag ctggtttaaa atgcccaagt
    15721 tccgcatgcc cagccttagg cgctctttca gggacagagg cggggctgga aagctggaag
    15781 tggctcagac acaggcaccg gcagcaacag ggggtgaagc agcagctaaa gtcaaagagt
    15841 tccttgtttc tgggtcaaac gtggaggcag ctatgtccct acagctccca gaggcagatg
    15901 cagaagtgac agcttctgag agcaaatcat ccacagatat tctaaggtgt gatcttgaca
    15961 gcacaggctt gaagctgcac ctctccactg ctgggatgac tggggatgag ctttccactt
    16021 ctgaggtcag gatccatcca tccaaaggac ctctcccttt tcagatgcct ggcatgaggc
    16081 ttccagaaac ccaggttctt ccaggagaaa tagatgagac tcctctttcc aagccaggac
    16141 atgaccttgc cagcatggag gataaaacag agaaatggtc ttcccagcct gaaggtccac
    16201 ttaaattgaa agcttcaagt actgatatgc catcccagat ttctgtggtt aatgtggatc
    16261 aactgtggga agattctgtc ctaactgtca aattccccaa attaatggta ccaaggttct
    16321 ccttccctgc ccccagctca gaggatgatg tgttcatccc cactgtgagg gaagtgcagt
    16381 gtccagaggc caatattgat acagcccttt gtaaggaaag tccggggctc tggggagcca
    16441 gcatcctgaa ggcaggtgct ggggtccctg gggagcagcc tgtggacctt aacctgcctt
    16501 tggaagctcc cccaatttca aaggtcagag tgcatattca gggtgctcag gttgaaagtc
    16561 aagaggtcac tatacacagc atagtgacac cagagtttgt agatctctca gtacccagga
    16621 ctttttccac tcagattgtg cgggaatcag agatccccac gtcagagatt caaacacctt
    16681 cgtacggatt ttccttatta aaagtgaaaa tcccagagcc ccacacgcag gctagagtgt
    16741 acacaacaat gactcaacac tctaggactc aggagggcac agaagaggct cccatacaag
    16801 ccaccccagg agtagactcc atttctggag atctccagcc tgacactgga gaaccatttg
    16861 agatgatctc ttccagcgtc aatgtactgg gacagcaaac actcacattt gaagttcctt
    16921 ctggccacca gcttgcagac agctgttcag atgaggagcc agcagaaatt cttgagtttc
    16981 cccctgatga tagccaagag gcaaccacac cactggcaga tgaaggcagg gctccaaaag
    17041 acaaaccaga aagtaaaaaa tctggtctgc tctggttttg gcttccaaac attgggtttt
    17101 cctcttctgt tgatgagaca ggtgttgatt ccaaaaatga cgtccagaga tctgctccca
    17161 ttcaaacaca gcctgaggca cgaccagagg cagaactgcc taaaaaacag gagaaggcag
    17221 gctggttccg atttcccaaa ttagggttct cctcatctcc taccaagaaa agcaaaagca
    17281 ccgaagatgg ggcagagctg gaagaacaaa aacttcaaga agaaacaatc acgttttttg
    17341 atgcccgaga aagtttctcc cctgaagaga aggaagaggg tgaactgatc gggcctgtgg
    17401 gcactgggct ggactccaga gtgatggtga catccgcggc aagaacagag ttaatcctgc
    17461 ccgagcagga cagaaaagct gacgatgaaa gcaaagggtc aggcctggga ccaaatgaag
    17521 gctgagaggt atggctcatc agtacaagag agatgcaaaa aactaagttg gaaagtaaag
    17581 gctacacaca catatggagc accccatccc acagcacatt acatccacct cacttcacag
    17641 aacggagaac agagcagaaa tgaccagaac acctttgtca ccatcacaca gccctcctaa
    17701 aatggaacca aagcttccca gctccctcaa agctttggat gcaaagaagg caccctgact
    17761 tccacaagac accagaattc acacggtact cagaggcact gctggggaag tttgttggtc
    17821 tttattagat aaatttccag agacctgtcc ataataccca acagaacatg actgtttctt
    17881 tgaggaaagg gttataatgt ctgtggtgta caagtcgttt ttggtataac ttctttcctg
    17941 ctgctgctgc ttcccggcaa acatagtttt cctatttcag gcagagtgcg gtatattcca
    18001 ggaaacactg tttcctactc acttagctta cttctttgtt gaatgcctca ctaatggcaa
    18061 gtttcaagat gttttgggtg acaatgcaca catgctgggc aaaagggtga tggccagtgg
    18121 ctggcagctg ggccagcaga agctaggaca tctgtgagtt gtcattctca tctatccatg
    18181 tccactggcc tgccagcatc cgccagtgcc ttgccagtgt gcacggtccc acactgtggc
    18241 ccctgagtcc cctaatgtac acgctgcagc cagaatgcag atggagctgg cttggctgtt
    18301 ccctggatgg gcaataaaga aagtgctgca tccca
//
