LOCUS       NM_001620              18761 bp    mRNA    linear   PRI 01-AUG-2024
DEFINITION  Homo sapiens AHNAK nucleoprotein (AHNAK), transcript variant 1,
            mRNA.
ACCESSION   NM_001620
VERSION     NM_001620.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 18761)
  AUTHORS   Lu,X., Mei,Y., Fan,C., Chen,P., Li,X., Zeng,Z., Li,G., Xiong,W.,
            Xiang,B. and Yi,M.
  TITLE     Silencing AHNAK promotes nasopharyngeal carcinoma progression by
            upregulating the ANXA2 protein
  JOURNAL   Cell Oncol (Dordr) 47 (3), 833-850 (2024)
   PUBMED   37962808
  REMARK    GeneRIF: Silencing AHNAK promotes nasopharyngeal carcinoma
            progression by upregulating the ANXA2 protein.
REFERENCE   2  (bases 1 to 18761)
  AUTHORS   Zhang,C. and Liu,Y.
  TITLE     Identification of AHNAK expression associated with the pathogenesis
            of chronic obstructive pulmonary disease by bioinformatic analysis
  JOURNAL   Acta Biochim Pol 70 (4), 761-766 (2023)
   PUBMED   38051912
  REMARK    GeneRIF: Identification of AHNAK expression associated with the
            pathogenesis of chronic obstructive pulmonary disease by
            bioinformatic analysis.
REFERENCE   3  (bases 1 to 18761)
  AUTHORS   Sun,L., Lu,J., Li,K., Zhang,H., Zhao,X., Li,G. and Li,N.
  TITLE     Diagnostic and prognostic value of STAP1 and AHNAK methylation in
            peripheral blood immune cells for HBV-related hepatopathy
  JOURNAL   Front Immunol 13, 1091103 (2023)
   PUBMED   36713363
  REMARK    GeneRIF: Diagnostic and prognostic value of STAP1 and AHNAK
            methylation in peripheral blood immune cells for HBV-related
            hepatopathy.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 18761)
  AUTHORS   He,S.L., Zhao,X. and Yi,S.J.
  TITLE     CircAHNAK upregulates EIF2B5 expression to inhibit the progression
            of ovarian cancer by modulating the JAK2/STAT3 signaling pathway
  JOURNAL   Carcinogenesis 43 (10), 941-955 (2022)
   PUBMED   35710311
  REMARK    GeneRIF: CircAHNAK upregulates EIF2B5 expression to inhibit the
            progression of ovarian cancer by modulating the JAK2/STAT3
            signaling pathway.
REFERENCE   5  (bases 1 to 18761)
  AUTHORS   Shi,Y., Zhang,L., Wang,L. and Ding,H.
  TITLE     Downregulation of Circ_0088196 Contributes to the Development of
            Trophoblastic Cells through miR-133b Sponging Function to Affect
            the AHNAK Expression
  JOURNAL   Gynecol Obstet Invest 87 (5), 305-315 (2022)
   PUBMED   36198257
  REMARK    GeneRIF: Downregulation of Circ_0088196 Contributes to the
            Development of Trophoblastic Cells through miR-133b Sponging
            Function to Affect the AHNAK Expression.
REFERENCE   6  (bases 1 to 18761)
  AUTHORS   de Morree,A., Droog,M., Grand Moursel,L., Bisschop,I.J.,
            Impagliazzo,A., Frants,R.R., Klooster,R. and van der Maarel,S.M.
  TITLE     Self-regulated alternative splicing at the AHNAK locus
  JOURNAL   FASEB J 26 (1), 93-103 (2012)
   PUBMED   21940993
  REMARK    GeneRIF: AHNAK constitutes a novel mechanism in
            post-transcriptional control of gene expression.
REFERENCE   7  (bases 1 to 18761)
  AUTHORS   Gentil,B.J., Delphin,C., Mbele,G.O., Deloulme,J.C., Ferro,M.,
            Garin,J. and Baudier,J.
  TITLE     The giant protein AHNAK is a specific target for the calcium- and
            zinc-binding S100B protein: potential implications for Ca2+
            homeostasis regulation by S100B
  JOURNAL   J Biol Chem 276 (26), 23253-23261 (2001)
   PUBMED   11312263
REFERENCE   8  (bases 1 to 18761)
  AUTHORS   Kudoh,J., Wang,Y., Minoshima,S., Hashimoto,T., Amagai,M.,
            Nishikawa,T., Shtivelman,E., Bishop,J.M. and Shimizu,N.
  TITLE     Localization of the human AHNAK/desmoyokin gene (AHNAK) to
            chromosome band 11q12 by somatic cell hybrid analysis and
            fluorescence in situ hybridization
  JOURNAL   Cytogenet Cell Genet 70 (3-4), 218-220 (1995)
   PUBMED   7789175
REFERENCE   9  (bases 1 to 18761)
  AUTHORS   Shtivelman,E., Cohen,F.E. and Bishop,J.M.
  TITLE     A human gene (AHNAK) encoding an unusually large protein with a
            1.2-microns polyionic rod structure
  JOURNAL   Proc Natl Acad Sci U S A 89 (12), 5472-5476 (1992)
   PUBMED   1608957
  REMARK    Erratum:[Proc Natl Acad Sci U S A 1993 May 1;90(9):4328]
REFERENCE   10 (bases 1 to 18761)
  AUTHORS   Osborn,M., Johnsson,N., Wehland,J. and Weber,K.
  TITLE     The submembranous location of p11 and its interaction with the p36
            substrate of pp60 src kinase in situ
  JOURNAL   Exp Cell Res 175 (1), 81-96 (1988)
   PUBMED   3126079
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK300376.1, AP001363.4 and
            BE873999.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_001620.2.
            
            Summary: The protein encoded by this gene is a large (700 kDa)
            structural scaffold protein consisting of a central domain with 128
            aa repeats. The encoded protein may play a role in such diverse
            processes as blood-brain barrier formation, cell structure and
            migration, cardiac calcium channel regulation, and tumor
            metastasis. A much shorter variant encoding a 17 kDa isoform exists
            for this gene, and the shorter isoform initiates a feedback loop
            that regulates alternative splicing of this gene. [provided by
            RefSeq, Oct 2016].
            
            Transcript Variant: This variant (1, also known as L-AHNAK)
            represents the longest transcript and encodes the longer isoform
            (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK300376.1, AK095346.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2467146, SAMEA2467147
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000378024.9/ ENSP00000367263.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-839               AK300376.1         30-868
            840-18373           AP001363.4         11982-29515         c
            18374-18761         BE873999.1         1-388
FEATURES             Location/Qualifiers
     source          1..18761
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.3"
     gene            1..18761
                     /gene="AHNAK"
                     /gene_synonym="AHNAK1; AHNAKRS; PM227"
                     /note="AHNAK nucleoprotein"
                     /db_xref="GeneID:79026"
                     /db_xref="HGNC:HGNC:347"
                     /db_xref="MIM:103390"
     exon            1..147
                     /gene="AHNAK"
                     /gene_synonym="AHNAK1; AHNAKRS; PM227"
                     /inference="alignment:Splign:2.1.0"
     exon            148..246
                     /gene="AHNAK"
                     /gene_synonym="AHNAK1; AHNAKRS; PM227"
                     /inference="alignment:Splign:2.1.0"
     CDS             247..17919
                     /gene="AHNAK"
                     /gene_synonym="AHNAK1; AHNAKRS; PM227"
                     /note="isoform 1 is encoded by transcript variant 1;
                     AHNAK-related; desmoyokin; neuroblast
                     differentiation-associated protein AHNAK"
                     /codon_start=1
                     /product="neuroblast differentiation-associated protein
                     AHNAK isoform 1"
                     /protein_id="NP_001611.1"
                     /db_xref="CCDS:CCDS31584.1"
                     /db_xref="GeneID:79026"
                     /db_xref="HGNC:HGNC:347"
                     /db_xref="MIM:103390"
                     /translation="MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAA
                     RTGVVKEGDQIVGATIYFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTR
                     EVFSSCSSEVVLSGDDEEYQRIYTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAY
                     TVDVTGREGAKDIDISSPEFKIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPT
                     GSAVDIRAGAISASGPELQGAGHSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVP
                     AVDISSSLGGRAVEVQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAP
                     EVSVGHKGGKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLEGDLGLKGAKPQ
                     GHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETG
                     IDVTLPTGEVTVPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLS
                     LGSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGT
                     CRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEVDVRGPKVDVSAPDVEAHGPEW
                     NLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKG
                     PDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDAPDVDV
                     HGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISGPKIDVTAPDVSIEEPE
                     GKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKS
                     AKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVG
                     VEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMTVPKLE
                     GDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSKANVDIS
                     APKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKGNVDIS
                     APKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGPEV
                     DVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLHL
                     KGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKF
                     SMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKA
                     PKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDW
                     HLKMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKG
                     PKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDI
                     NAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPD
                     VNLEAPEGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKG
                     PEIDVKAPKMDVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVK
                     GDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFK
                     AEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMP
                     DVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPK
                     FKMPEMHFKAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELEC
                     PDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGV
                     EVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEG
                     EMKVPDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPK
                     ADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKVK
                     GDVDVSLPKLEGDLTGPSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVN
                     LNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHLKMPKMKM
                     PKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMH
                     FKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGPKLDADMPEVAVEG
                     PNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVDVPKLEGDLKGPHVDV
                     SGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEG
                     KLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKAD
                     VDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKGPKVKGD
                     VDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPGFKGE
                     GPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDI
                     DLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIK
                     MPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEM
                     HFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQ
                     GPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIEGPEG
                     KLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIRGP
                     QVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDI
                     DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEG
                     DMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPK
                     ADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGPKMK
                     GEVDVSLANVEGDLKGPALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPK
                     ISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGKSKKS
                     RFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFL
                     SISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVH
                     GPDWNLKMPKMKMPKFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEGPDLNVEGPEG
                     GLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGP
                     KVDINAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDV
                     DVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEG
                     DLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKG
                     PKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSM
                     PGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPK
                     ISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHL
                     KMPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPK
                     FKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDA
                     PDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDID
                     IHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPE
                     VDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVS
                     GPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVS
                     LPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDV
                     DVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNL
                     KGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKGPKFKMPEM
                     NIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEGKLKGPKFKMP
                     DVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKVGIDTPDID
                     IHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPE
                     VDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVS
                     GPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVDVT
                     LPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDV
                     DVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDL
                     KGPKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKV
                     TAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPK
                     FKKPKFGFGAKSPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSG
                     PKIKAKKQGFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYF
                     PDVEFDIKSPKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDV
                     DISVPKIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGP
                     KIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEG
                     DLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSM
                     KVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDI
                     KCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGV
                     DVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPG
                     IKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPE
                     SDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSK
                     FAGGLHFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSG
                     RELVGREMGVDVHFPKAEASIQAGAGDGEWEESEVKLKKSKIKMPKFNFSKPKGKGGV
                     TGSPEASISGSKGDLKSSKASLGSLEGEAEAEASSPKGKFSLFKSKKPRHRSNSFSDE
                     REFSGPSTPTGTLEFEGGEVSLEGGKVKGKHGKLKFGTFGGLGSKSKGHYEVTGSDDE
                     TGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPEVELSVSTKKE"
     exon            247..400
                     /gene="AHNAK"
                     /gene_synonym="AHNAK1; AHNAKRS; PM227"
                     /inference="alignment:Splign:2.1.0"
     exon            401..588
                     /gene="AHNAK"
                     /gene_synonym="AHNAK1; AHNAKRS; PM227"
                     /inference="alignment:Splign:2.1.0"
     exon            589..18761
                     /gene="AHNAK"
                     /gene_synonym="AHNAK1; AHNAKRS; PM227"
                     /inference="alignment:Splign:2.1.0"
     regulatory      18738..18743
                     /regulatory_class="polyA_signal_sequence"
                     /gene="AHNAK"
                     /gene_synonym="AHNAK1; AHNAKRS; PM227"
                     /note="hexamer: AATAAA"
     polyA_site      18761
                     /gene="AHNAK"
                     /gene_synonym="AHNAK1; AHNAKRS; PM227"
                     /note="major polyA site"
ORIGIN      
        1 ggccactcgg agctgctctg ccgcggggac tgcaccgccc gccctgccag acccgcccgg
       61 aacggggctc gtcgccgcca gtagccgcag caccgcagcc ttgggcctcg cgccggctat
      121 ggccgtgccc tggggctgag ccctcaggtt gtgaccgaga ttcccgacga gagagactga
      181 ggggaagaga ggaaggaggg gcgggctcct ggcaaggcat tcgctcctga gcggaatcct
      241 gcaaagatgg agaaggagga gacaacccgg gagctgctgc tgcccaactg gcagggtagt
      301 ggctcccacg ggctgaccat cgcccagagg gacgacggcg tctttgtgca ggaggtgacg
      361 cagaactccc ctgcggcccg cactggggtg gtcaaggagg gggaccagat tgtgggtgcc
      421 accatctact ttgacaacct gcagtcgggt gaggtgaccc agctgctgaa caccatgggg
      481 caccacacgg tgggcctgaa gctgcaccgc aagggggacc gctctcccga gcctggccag
      541 acctggaccc gtgaagtctt cagctcctgc agctctgaag tggttctgag cggggatgat
      601 gaggagtacc agcgcatcta caccacgaag atcaagccac ggctgaagtc ggaagatgga
      661 gtggaaggag acctcgggga gacccagagc cgtaccatca cagtgaccag aagggtcacg
      721 gcctacactg tggatgtgac tggccgggaa ggagccaagg acatagacat cagtagccct
      781 gaattcaaga tcaagattcc aagacatgaa ctgactgaaa tctccaatgt ggatgtggag
      841 acccagtctg ggaagaccgt gatcagactg ccctcgggct cgggggcagc ctctccgaca
      901 ggctctgctg tggatatccg agcaggggcc atttctgctt caggaccaga gctccaaggt
      961 gctggccact cgaagctcca ggtcaccatg cctgggataa aggtgggagg ctcaggtgtc
     1021 aatgtcaatg caaagggctt ggacttgggt ggcagaggag gggtccaagt tccagcagtg
     1081 gacatttcat cttctcttgg gggtagggca gtagaggtac agggcccatc tctggagagt
     1141 ggtgatcatg gcaaaattaa atttcccacc atgaaagtgc cgaaatttgg tgtctcaaca
     1201 gggcgtgagg gccagacacc aaaggcaggg ctgagggttt ctgcacctga agtctctgtg
     1261 gggcacaagg gcggcaagcc aggcttgact atccaagccc ctcagctgga agtcagtgtg
     1321 ccctctgcca atattgaggg ccttgagggg aagctgaagg gcccccaaat cactgggcca
     1381 tcacttgagg gtgacctagg cctgaaaggt gccaagccac aggggcacat tggggtggat
     1441 gcctctgctc cccaaattgg gggtagcatc actggcccca gtgtggaagt tcaggcccct
     1501 gacattgatg ttcaggggcc tgggagcaaa ctgaatgtgc ccaagatgaa agtccccaag
     1561 ttctctgtat caggtgcaaa gggagaggaa actgggattg atgtgacact gcctacaggt
     1621 gaagtgactg ttcctggggt ctctggggat gtcagcctgc ctgagattgc tactggtggg
     1681 ctggaaggaa agatgaaagg tactaaagtg aagactcctg aaatgattat tcagaaacct
     1741 aaaatctcca tgcaggatgt ggatctgagc cttgggtctc ctaaactgaa aggagatatt
     1801 aaggtttctg ctcctggggt gcaaggtgat gttaaaggcc ctcaagtggc acttaaaggc
     1861 tccagagtgg acatagagac accaaaccta gagggaacct tgacaggccc taggcttggc
     1921 agtccttccg ggaaaaccgg aacctgtagg atctctatgt cagaagtaga cttaaatgtg
     1981 gccgcaccta aagtgaaagg gggtgtagat gtcacactcc ccagagtaga agggaaagtc
     2041 aaagtccctg aagttgatgt cagaggcccc aaagtggatg tcagtgcccc agatgtcgaa
     2101 gcgcatggcc cagaatggaa cctgaaaatg cccaagatga aaatgcccac gttcagcact
     2161 ccaggagcca aaggggaagg tccagatgtt catatgactc tacccaaagg agatatcagt
     2221 atttcagggc ccaaggtcaa tgtggaagcc ccagatgtca acttggaggg tctgggggga
     2281 aaacttaaag gccccgatgt taagctgcct gatatgagtg tcaagacacc aaagatctcc
     2341 atgcctgatg tagatttgca cgtgaaaggt acaaaggtga agggagagta tgatgtaact
     2401 gtaccaaagc tggaaggaga actcaaaggc ccaaaagtgg acattgatgc cccagatgtg
     2461 gatgttcatg gcccagactg gcacttgaag atgcccaaga tgaaaatgcc caaattcagt
     2521 gtgccagggt tcaaagcaga gggcccagaa gtggatgtga acctgcccaa ggctgatgtg
     2581 gacatttccg ggcccaagat agatgttact gctcctgatg tgagcattga ggaaccagaa
     2641 gggaaattga aagggcccaa gtttaagatg cctgagatga acatcaaagt ccccaagatc
     2701 tccatgcctg atgtggactt acatctgaaa ggccctaacg taaagggaga atatgatgtc
     2761 acaatgccaa aggttgaaag tgagattaaa gttcctgatg ttgaacttaa aagtgccaaa
     2821 atggacattg atgtcccaga tgtggaggtt caaggcccag actggcacct gaagatgccc
     2881 aagatgaaaa tgcccaagtt cagcatgcct ggcttcaaag cagagggccc agaagtggat
     2941 gtgaacctgc ccaaggctga tgtggacatc tcaggaccca aggtgggtgt tgaagttcca
     3001 gatgtgaata ttgaaggacc tgaaggaaag ctgaagggcc ccaagttcaa gatgccagag
     3061 atgaatatca aggcccccaa gatctccatg cctgatgtgg acttgcatat gaaaggtcct
     3121 aaagtaaagg gagaatatga tatgacagtg ccaaagctgg aaggggacct gaaaggccca
     3181 aaagtagatg tcagtgcccc agatgttgaa atgcagggtc ctgactggaa cttgaagatg
     3241 ccaaagatta aaatgcccaa atttagcatg cccagcctca aaggagaggg gccagaattt
     3301 gatgtgaacc tgtccaaagc gaatgtggac atttctgcac caaaagtaga tactaatgct
     3361 ccagatctga gccttgaagg acctgaaggg aagttgaaag gcccgaagtt taagatgcct
     3421 gagatgcact tcagagctcc taagatgtct ttgccagatg ttgacctgga tcttaaagga
     3481 cccaaaatga aaggaaatgt agatatctct gcaccaaaga tagagggtga aatgcaggtt
     3541 ccagatgtgg acatcagagg tcccaaggta gatattaaag caccagatgt ggaaggccaa
     3601 ggcctggact ggagcctgaa aatacccaag atgaaaatgc ccaagttcag catgcccagc
     3661 ctcaaaggcg agggcccaga agtggatgtg aacttgccta aggctgacgt tgttgtctca
     3721 ggacccaagg tggacatcga agccccagat gtgagcctcg aaggtccaga agggaagctg
     3781 aagggtccca agtttaagat gcctgagatg catttcaaga cccccaagat ctccatgcct
     3841 gatgtggact tacacttgaa aggccccaaa gtcaaagggg atgtggatgt gtctgtgccc
     3901 aaggtagaag gtgaaatgaa agtgccagat gttgaaatca aaggacccaa aatggacatt
     3961 gatgccccag atgtggaggt tcaaggccca gactggcacc tgaagatgcc caagatgaaa
     4021 atgcccaagt ttagcatgcc tggcttcaaa ggagagggcc gagaagtgga tgtgaacctg
     4081 cccaaggctg acattgatgt ctcaggaccc aaggtggatg ttgaagtccc agatgtgagc
     4141 cttgagggcc cggaaggaaa gctgaagggc cccaagttta agatgcctga gatgcacttc
     4201 aaggccccca agatctccat gcctgatgtg gacctgaatc ttaaggggcc aaaattgaag
     4261 ggagatgtgg atgtgtcctt gcctgaggta gaaggtgaaa tgaaagtgcc agatgttgac
     4321 attaaagggc ccaaagttga cattagtgct ccagatgtgg atgttcatgg cccagattgg
     4381 cacctgaaga tgcccaaggt gaaaatgccc aagttcagca tgcccggctt caaaggagag
     4441 ggccctgaag tggatgtgaa gctgcccaaa gctgacgttg atgtctcagg acccaaaatg
     4501 gatgctgaag ttccagatgt gaatattgaa ggtccagacg caaaactaaa aggtcccaaa
     4561 ttcaagatgc cagaaatgag tataaagcct cagaagatat ccataccaga tgttggtttg
     4621 catttgaaag gtcctaaaat gaaaggagat tatgatgtaa cagttccaaa agtagaagga
     4681 gagataaaag ctcctgatgt tgacatcaaa ggccccaaag ttgatattaa tgcaccagat
     4741 gtggaggttc atggcccaga ctggcacctg aagatgccca aggtaaaaat gcccaagttc
     4801 agcatgcctg gctttaaagg agagggccca gaggtggata tgaacctgcc caaggctgac
     4861 cttggtgttt caggacccaa ggtggacatt gatgttccag atgtgaatct tgaagctcca
     4921 gaggggaaac taaaaggccc taagttcaag atgccaagca tgaatataca gacgcacaaa
     4981 atctctatgc ctgatgttgg acttaatttg aaagccccta aactgaaaac tgatgtagat
     5041 gtttcccttc ccaaagtgga aggagacttg aagggtcctg aaattgatgt gaaagcccct
     5101 aagatggatg tgaatgttgg tgatattgat attgaaggtc cagaagggaa gttgaagggc
     5161 cccaagttta agatgcctga gatgcatttc aaggccccca agatctccat gcccgatgtg
     5221 gacttacact tgaaaggccc caaagtcaaa ggggatatgg atgtgtctgt gcccaaggta
     5281 gaaggtgaaa tgaaagtgcc agatgttgac attaaagggc ccaaagtgga cattgatgcc
     5341 ccagatgtgg aggttcacga cccagattgg cacctgaaaa tgcccaagat gaaaatgccc
     5401 aagttcagta tgcctggctt caaagcagag ggccctgaag tggatgtgaa tctgccaaag
     5461 gctgacattg atgtgtctgg acccagtgtg gacactgatg ctcctgattt ggatattgag
     5521 ggaccagaag gaaagttgaa aggctccaaa tttaagatgc ccaagttgaa tataaaagct
     5581 cccaaggtct ccatgccaga tgtggacttg aatttgaagg gacccaaact gaagggagag
     5641 atagatgctt ctgtgccaga actggaaggt gatctcagag ggccgcaagt tgatgtcaaa
     5701 ggtccttttg tggaagcgga ggtgcccgat gttgatctgg agtgtcctga tgcaaagttg
     5761 aaagggccca agtttaagat gcctgagatg cacttcaagg cccccaagat ctccatgcct
     5821 gatgtggact tacacctgaa aggccccaaa gtcaaagggg atgcggatgt gtcggtgcca
     5881 aaattggagg gagatttaac aggccccagt gtgggtgtgg aggtgcctga tgttgagctg
     5941 gagtgtcctg atgcaaagtt gaaaggccct aaatttaaga tgccagacat gcacttcaag
     6001 gcccccaaga tctccatgcc tgatgtggac ttacacttga aaggccccaa agtcaaaggg
     6061 gatgtggatg tgtcggtgcc aaaattggag ggagatttaa caggtcccag tgtgggtgtg
     6121 gaggtgcctg atgttgagct ggagtgtcct gatgcaaagt tgaaagggcc caagtttaag
     6181 atgcctgaga tgcacttcaa gacccccaag atctccatgc ctgatgtgga cttacacctg
     6241 aaaggcccca aagtcaaagg ggatatggat gtgtctgtgc ccaaggtaga aggtgaaatg
     6301 aaagtgccag atgttgacat caaaggaccc aaaatggaca ttgatgcccc agatgtggat
     6361 gttcatggcc cagactggca cctgaagatg cccaagatga aaatgcccaa gttcagcatg
     6421 cctggcttca aagcagaggg cccagaagtg gatgtgaact tgcccaaggc tgatgttgtt
     6481 gtctcaggac ccaaggtgga tgttgaagtc ccagatgtga gccttgaagg tccagaaggg
     6541 aagctgaagg gccccaagct taagatgcct gagatgcact tcaaggcccc caagatctcc
     6601 atgcctgatg tggacttaca cttgaaaggc cccaaagtca aaggggatgt ggatgtgtct
     6661 ttgccaaaat tggagggaga tttaacaggc cccagtgtgg atgtggaggt gcctgatgtt
     6721 gagctggagt gtcctgatgc aaagttgaaa gggcccaagt ttaagatgcc tgagatgcac
     6781 ttcaagaccc ccaagatctc catgcctgat gtgaacttaa acttgaaagg ccccaaagtc
     6841 aaaggggata tggatgtgtc tgttcccaag gtagaaggtg aaatgaaagt gccagatgtt
     6901 gacatcagag ggcccaaagt ggacattgat gccccagatg tggatgttca tggcccagac
     6961 tggcacctga agatgcctaa gatgaaaatg cccaagttca gcatgcctgg cttcaaagga
     7021 gagggcccag aagtggatgt gaacttgccc aaggctgacg ttgatgtctc aggacccaag
     7081 gtggatgttg aagtcccaga tgtgagcctt gaaggtccag aagggaagct gaagggcccc
     7141 aagtttaaga tgcctgagat gcacttcaag acccccaaga tctccatgcc tgatgttgat
     7201 ttcaatttaa agggacccaa aatcaaagga gatgttgatg tttctgcccc aaagctggag
     7261 ggagagttaa aaggtccaga attggatgtc aaaggtccca aattagatgc tgacatgcca
     7321 gaagtagctg tggaaggccc aaatggcaag tggaaaactc ctaagttcaa gatgccagat
     7381 atgcacttta aagctcccaa aatctctatg ccagacctcg atctacactt gaagagcccc
     7441 aaggcaaaag gagaggtgga tgtagatgtt cccaaattgg aaggggacct taaagggcca
     7501 catgtggatg tcagtgggcc agacattgac attgagggac cagagggcaa attgaaaggc
     7561 cctaagttca agatgcctga tatgcatttc aaagccccca atatttctat gcctgatgtt
     7621 gatctaaatc tcaaaggacc caaaatcaag ggggatgtgg atgtgtctgt gcctgaggta
     7681 gaaggtaaac ttgaagtacc agatatgaac atcaggggcc ccaaagttga tgtaaatgcc
     7741 cccgatgtcc aagctccaga ctggcacctg aagatgccca agatgaaaat gcccaagttc
     7801 agcatgcctg gcttcaaagc agagggccct gaagtagacg tcaacttgcc taaggctgac
     7861 gttgacatct caggacccaa ggtggacatt gaaggccctg atgttaatat tgaaggacca
     7921 gagggaaagt tgaaagggcc taagttaaag atgccagaga tgaacatcaa agcccccaag
     7981 atctccatgc ctgactttga tttgcatctg aaaggtccca aggtgaaggg cgatgtggat
     8041 gtttctctgc ccaaagtgga aggtgacctc aagggccccg aagttgacat caaggggccc
     8101 aaagtggata ttaatgcccc agatgtgggt gttcaaggcc cagactggca cctgaagatg
     8161 cccaaggtga aaatgccaaa gttcagcatg cctggcttca aaggagaggg cccagatggg
     8221 gatgtgaagc tgcccaaggc tgacattgat gtctcaggac ccaaagtgga cattgaaggc
     8281 cctgatgtta acattgaagg accagaggga aagttgaaag ggcctaagtt caagatgcca
     8341 gagatgaata tcaaagcccc caagatctcc atgcctgata ttgacttaaa cctgaaagga
     8401 cccaaagtga agggtgatgt ggatgtttcc cttcctaaag tggaaggtga cctcaagggc
     8461 ccagaagttg acatcaaggg cccaaaagtg gacattgacg cacctgatgt tgatgttcat
     8521 ggcccagact ggcacctaaa gatgcccaag ataaaaatgc ccaagatcag catgcctggc
     8581 ttcaaaggag aaggtccaga tgtggacgtg aacctgccca aggctgacat tgatgtctca
     8641 ggaccgaaag tggatgttga atgtcccgat gtgaatatcg aaggacctga aggaaagtgg
     8701 aaaagtccaa agtttaagat gccagagatg cattttaaga ctccaaagat atccatgcca
     8761 gatattgacc tgaatctcac aggtccaaaa ataaaaggag atgtggatgt tacaggccct
     8821 aaggtagagg gagatctgaa aggtcctgaa gttgacctca aaggccccaa agtggacatt
     8881 gatgtcccag atgttaatgt tcagggtcca gactggcacc tgaagatgcc caagatgaaa
     8941 atgcccaagt tcagcatgcc tggcttcaaa gcagagggcc ctgaagtgga tgtgaacctg
     9001 cccaaggctg acgttgatgt ctcaggcccc aaagtggacg ttgaaggccc tgatgttaac
     9061 attgaaggac cagagggaaa gttgaaaggg cccaagttca agatgccaga gatgaatatc
     9121 aaagccccca agatccccat gcctgacttt gatttgcatc tgaaaggtcc caaggtgaag
     9181 ggcgatgtgg atatttctct gcccaaagtg gaaggtgacc tcaagggccc tgaagttgac
     9241 atcaggggtc cccaagtgga cattgatgtc ccggatgtgg gcgttcaagg cccagactgg
     9301 cacctaaaaa tgcccaaagt gaaaatgccc aaattcagca tgcctggctt caaaggagag
     9361 ggcccagatg tggatgtgaa cctgcccaag gctgaccttg atgtctcagg acccaaggtg
     9421 gacattgatg ttccagatgt gaatatcgaa ggcccagagg gaaagttgaa aggtcccaaa
     9481 ttcaaaatgc ctgagatgaa catcaaagcc cccaagatct ccatgcctga cattgatctt
     9541 aacctgaaag gtcccaaagt gaagggtgac atggatgtgt ctctgccaaa agtggaaggt
     9601 gacatgaaag ttcctgacgt ggatattaaa ggccccaaag tggatattaa tgccccagat
     9661 gtggatgttc aaggcccaga ctggcacctg aagatgccta aaataaaaat gcccaagatc
     9721 agcatgcctg gcttcaaagg agaaggtcca gaagtggacg tgaacctgcc caaggctgac
     9781 cttgacgtct caggacccaa ggtggacgtt gatgttccag atgtgaatat tgaaggtcca
     9841 gatgcgaaac tgaagggccc taaattcaag atgccagaga tgaacatcaa agctcctaaa
     9901 atatcaatgc ctgatttgga cctcaatctt aaaggcccta aaatgaaagg agaggtggat
     9961 gtttcacttg caaatgtaga aggtgatttg aaaggacctg ctcttgacat aaaaggccca
    10021 aagatagatg tagatgctcc agatattgac attcatggcc cagatgccaa attaaaaggt
    10081 ccaaaactga agatgcctga catgcatgta aacatgccca agatctccat gccagaaatt
    10141 gacttgaatt tgaaaggctc aaagcttaag ggagatgttg atgtctctgg gcccaagttg
    10201 gaaggtgaca ttaaagctcc cagtttggat ataaagggcc cagaagtgga cgtttccggt
    10261 cctaagctta atatcgaagg caagtcaaag aaatctcgtt ttaagcttcc caaatttaat
    10321 ttttcgggct ctaaagttca gacacctgaa gtggatgtca aaggtaaaaa gccagatatt
    10381 gacataacag gtccaaaagt tgatattaat gctcctgatg tcgaggtcca aggaaaagtg
    10441 aaaggatcca agtttaaaat gcctttcctg agtatttcat ctcccaaagt ttctatgcct
    10501 gacgtggagc taaatttgaa aagtcccaaa gtcaaaggag acttagatat tgcaggtccc
    10561 aatttagaag gtgactttaa aggccccaaa gtggatatta aggcaccaga agtcaatctt
    10621 aatgcacctg atgtggatgt tcatggtcca gactggaatc tgaaaatgcc caagatgaaa
    10681 atgcccaaat tcagtgtgtc tggcttaaaa gcagaagggc cagatgtagc tgtggatcta
    10741 ccaaaaggag acatcaacat agagggccca agtatgaaca ttgagggccc agatctcaat
    10801 gtggaaggtc cggagggagg cttgaaaggt cccaaattca agatgcctga catgaatatc
    10861 aaagctccca agatctccat gcctgacatt gacttaaact tgaaaggccc caaggtgaaa
    10921 ggtgatgtgg atatttctct tcccaaactt gaaggggatc tgaaagggcc agaggttgat
    10981 atcaaaggcc ctaaagtgga catcaatgcc ccagatgtgg atgttcatgg tccagactgg
    11041 catctgaaga tgcccaaagt gaaaatgccc aagttcagca tgcctggctt caaaggagaa
    11101 ggccctgaag tcgatgttac cctccctaaa gctgacattg acatttctgg tcccaatgta
    11161 gacgttgatg ttccagacgt gaatattgaa ggtccagatg caaagctgaa gggccccaag
    11221 ttcaagatgc ctgagatgaa catcaaagcc cccaagatct ccatgcctga ctttgacctg
    11281 aacttgaagg gacccaaaat gaagggtgat gtggttgtgt ctttgcccaa agtggaaggt
    11341 gatctaaaag gccctgaggt ggacatcaag ggccccaaag tggacattga cactcctgac
    11401 attaacatcg aaggctcaga gggtaaattc aagggaccca aatttaagat accagagatg
    11461 cacctgaagg ctcccaaaat atcgatgcct gacattgatt taaacctgaa gggccccaaa
    11521 gtcaagggcg atgtggatgt ttctctgccc aaaatggaag gtgacctcaa gggtcctgaa
    11581 gttgacatca agggccccaa agtggacatt aatgctccag atgttgatgt tcaaggccca
    11641 gactggcacc tgaagatgcc caaggtgaaa atgcccaagt tcagcatgcc tggcttcaaa
    11701 ggagagggcc cagatgtgga tgtgaacctg cccaaggctg accttgatgt ctcaggaccc
    11761 aaggtggaca ttgatgttcc agatgtgaat atcgaaggcc cagagggaaa gttgaaaggt
    11821 cccaaattca agatgcctga gatgaacatc aaagccccca agatctccat gcctgacatt
    11881 gatcttaacc tgaaaggacc caaagtgaag ggtgatatgg atgtgtctct gccaaaagtg
    11941 gaaggtgaca tgcaagttcc tgacttggat attaaaggcc ccaaagtgga tattaatgcc
    12001 ccagatgtgg atgttcgagg cccagactgg cacctgaaga tgcctaagat aaaaatgccc
    12061 aagatcagca tgcctggctt caaaggagaa ggtccagaag tggatgtgaa cctgcccaag
    12121 gctgaccttg acgtctcagg acccaaggtg gacgttgatg ttccagatgt gaatattgaa
    12181 ggtccagatg cgaaactgaa gggccctaaa ttcaagatgc cagagatgaa catcaaagcc
    12241 cccaagatct ccatgcctga ctttgatttg catctgaaag gccctaaggt gaaaggagat
    12301 gtggatgttt ctctgcctaa gatggaaggt gatctaaagg cccctgaagt tgacatcaag
    12361 ggccccaaag tggacattga tgccccagat gtggatgttc atggcccaga ctggcacctg
    12421 aagatgccca aggtgaaaat gcccaaattc agcatgccag gatttaaagg agagggccca
    12481 gaagtggatg ttaatttgcc caaagctgac attgatgtct caggacccaa agtggacatt
    12541 gacactcctg atattgatat tcatggtcca gaagggaaac tgaagggccc caaatttaaa
    12601 atgcctgacc tgcacctcaa ggcaccgaag atctctatgc ctgaagttga cctgaatctg
    12661 aaaggtccaa agatgaaggg cgacgtggac gtttctctgc ccaaagtgga aggcgacctc
    12721 aagggccctg aagttgacat caagggcccc aaagtggaca ttgatgtccc agatgtggac
    12781 gttcaaggcc cagactggca cttaaaaatg cccaaagtga aaatgcccaa gttcagcatg
    12841 cctggcttca aaggagaggg cccagatgtg gatgtgaacc tgcccaaggc tgaccttgac
    12901 gtctcaggac ccaaggtgga cattgatgtt cctgatgtga atatcgaagg tccagatgcg
    12961 aaactaaagg gccctaaatt caagatgcct gagatgaaca tcaaagcccc caagatctcc
    13021 atgcctgact ttgatttgca tctgaaaggt cccaaggtga agggtgatgt ggatgtttcc
    13081 cttcctaaag tggaaggtga cctcaagggc ccagaagttg acatcaaggg ccccaaagtg
    13141 gacatcgatg cccctgatgt agatgttcat ggcccagact ggcacctgaa gatgcccaag
    13201 gtgaaaatgc ccaaattcag catgccagga ttcaaaggag agggcccaga tgtggatgtt
    13261 acccttccta aggctgacat tgagatttct ggccccaaag tggacattga tgcccctgat
    13321 gtcagtatcg aaggtccaga tgcaaaactc aagggtccaa agttcaagat gccagagatg
    13381 aacatcaagg cccccaaaat ctccatgcct gacattgact ttaacttgaa gggtcccaaa
    13441 gtgaaaggtg atgtggatgt ctctctgccc aaagtggaag gtgatctcaa gggccctgaa
    13501 attgacataa aaggccccag tttggacatt gacacacctg atgtcaatat tgaaggtccg
    13561 gaaggaaaat tgaaggggcc caaatttaag atgcctgaga tgaacatcaa agctcccaaa
    13621 atctctatgc ctgactttga tttgcacctg aaaggtccca aggtgaaggg tgatgtggat
    13681 gtttcactac ctaaggtgga aagtgatctg aaagggccag aggtagacat tgaaggtcct
    13741 gaagggaagc tcaaaggtcc caagtttaag atgcctgatg tacatttcaa aagcccacaa
    13801 atctccatga gtgacattga tttgaatttg aaaggaccta agataaaagg agatatggac
    13861 atttccgttc ctaaactgga gggagatctg aaaggtccca aagtggatgt caaaggccct
    13921 aaagtgggca ttgacactcc tgatattgac attcatggtc cagaagggaa actgaagggc
    13981 cccaaattta aaatgcctga cttacacctc aaggcaccga agatctctat gcctgaagtt
    14041 gacctgaatc tgaaaggtcc aaaggtgaag ggcgacatgg acatttctct gcccaaagtg
    14101 gaaggcgacc tcaagggccc cgaagttgac atcagggacc ccaaagtgga cattgatgtc
    14161 ccagatgtgg acgttcaagg cccagactgg cacctaaaaa tgcccaaagt gaaaatgccc
    14221 aagttcagca tgcctggctt caaaggagag ggcccagatg tggatgtgaa cctgcccaag
    14281 gctgacattg atgtctcagg acccaaagtg gacgttgatg ttcctgatgt gaatatcgaa
    14341 ggtccagatg cgaaactaaa gggccccaag ttcaagatgc ctgagatgag catcaaagcc
    14401 cccaagatct ccatgcctga tattgactta aacctgaaag gacccaaagt gaagggcgat
    14461 gtggatgtta cccttcctaa agtggaaggt gacctcaagg gcccagaagc tgacatcaag
    14521 ggcccaaaag tggacatcaa cacccctgat gtggatgttc atggcccaga ctggcacctg
    14581 aagatgccca aggtgaaaat gcccaaattc agcatgcctg gcttcaaagg agaaggtcca
    14641 gatgtggatg tgagcctgcc caaggccgac atcgatgtct cgggacccaa ggtggacgtt
    14701 gatattccag atgtgaatat cgaaggtcca gacgcaaaac tgaagggccc caagttcaag
    14761 atgcctgaaa taaatatcaa agctcccaag atctccatac ctgatgttga cctggatttg
    14821 aaaggaccca aagtaaaagg agattttgat gtgtctgtcc ctaaggttga agggactttg
    14881 aaaggcccag aagtagatct taaaggtcca cgtctggatt tcgaaggccc tgatgccaaa
    14941 ctcagtggcc catctttgaa gatgccatcg ctggagatat ctgctcctaa agtaactgct
    15001 cctgatgttg atttgcatct caaggcacca aaaattggat tttcaggtcc gaagttagaa
    15061 ggtggtgaag tggacctcaa gggacccaaa gttgaagctc caagcttaga tgtacacatg
    15121 gacagcccag atattaacat cgaagggcca gatgttaaaa tccccaaatt taagaaaccc
    15181 aagtttggat ttggggcaaa aagccccaaa gctgacatca agtcaccttc actggatgtc
    15241 actgttcctg aggcagagct gaaccttgag actcctgaaa ttagtgttgg tggcaagggc
    15301 aagaaaagta agtttaaaat gcctaaaatt catatgagtg gtcctaagat taaggccaaa
    15361 aaacagggat ttgacctgaa tgttcctggg ggtgaaattg atgccagcct caaggctccg
    15421 gatgtagatg tcaacatcgc agggccggat gctgcactca aagtcgacgt gaaatcgccc
    15481 aaaaccaaga aaacgatgtt tggaaaaatg tacttcccag atgtagagtt tgacattaaa
    15541 tcacctaaat ttaaagctga ggcccctctc cctagcccca aactggaggg tgaactccag
    15601 gcacctgatc tggaactttc tttgccagcg attcacgtcg aaggtcttga catcaaggcg
    15661 aaggctccca aggtcaagat gccagatgtg gacatctcag tgccaaaaat agagggtgac
    15721 ctgaaaggcc ccaaagtgca ggcaaacttg ggtgcacctg acatcaacat cgaaggccta
    15781 gatgctaaag tcaaaacacc gtccttcggc atttctgccc ctcaagtctc catccctgat
    15841 gtgaatgtaa acttgaaagg accaaagata aagggtgatg tccccagcgt gggactggaa
    15901 ggaccagatg tagatctgca aggtccagaa gcaaaaatta agttccccaa gttttccatg
    15961 cccaagatcg gcatcccagg tgtgaaaatg gagggtgggg gagccgaggt ccatgcccag
    16021 ctaccctctc ttgaaggaga cttgagagga ccagatgtta agctcgaagg gcccgatgtt
    16081 tctctaaagg ggccaggagt agacttgcct tcagtgaacc tctctatgcc aaaagtctct
    16141 gggcctgacc ttgatctgaa cttgaaagga ccaagtttga agggagacct ggatgcatct
    16201 gttcccagca tgaaggtgca tgctccaggg ctcaacctca gtggtgtcgg tggcaaaatg
    16261 caggtgggag gagacggtgt gaaagtgcca gggatcgatg ccacaacaaa gcttaacgtt
    16321 ggggcaccag atgtgacact gaggggacca agcctgcagg gagatctggc tgtctctggt
    16381 gacatcaaat gccctaaagt atccgtagga gctcctgatc taagcttgga ggcatccgaa
    16441 ggcagcatta aacttcccaa aatgaagctg ccccaatttg gcatctctac tccggggtcc
    16501 gacttgcacg tcaatgccaa ggggccacag gtttctggcg aactgaaggg gccaggtgtg
    16561 gatgtgaacc tgaaagggcc tcggatttca gcaccgaatg tggactttaa cttggaagga
    16621 ccaaaagtga aagggagcct tggggccact ggtgagatca aaggccccac tgtcggagga
    16681 ggtcttccag gcattggtgt tcaaggccta gaaggaaacc tccagatgcc tggaattaag
    16741 tcctctggat gtgatgtgaa cctgccaggc gtgaatgtga aactcccaac tgggcagatt
    16801 tctgggcctg aaatcaaagg tggtctgaaa ggttcagaag taggtttcca tggggctgct
    16861 cctgatatca gtgtgaaggg gcctgccttt aatatggcat ctcctgagtc agattttggc
    16921 atcaacttga agggcccaaa aatcaaagga ggtgcggatg tttcaggggg tgtcagtgcc
    16981 ccagacatca gccttggtga agggcatttg agtgttaaag gttccggggg tgagtggaag
    17041 ggaccccaag tctcctctgc tctcaacttg gacacatcta agtttgctgg gggccttcat
    17101 ttctcaggac caaaggtgga aggaggtgtg aaaggaggtc agattggact ccaggctcct
    17161 gggctgagtg tgtctgggcc tcaaggtcac ttggaaagtg gatctggaaa agtaacattc
    17221 cctaaaatga agatccccaa atttaccttc tctggccgtg agctggttgg cagagaaatg
    17281 ggggtggatg ttcacttccc taaagcagag gccagcatcc aagctggtgc tggagacggc
    17341 gagtgggaag agtctgaagt caaactgaaa aagtccaaga tcaaaatgcc caagtttaat
    17401 ttttccaaac ctaaagggaa aggtggtgtc actggctcac cagaagcatc aatttctggg
    17461 tccaaaggtg acctgaaaag ttcaaaggcc agcctgggct ctctggaagg agaggcagag
    17521 gccgaagcct cttcaccgaa aggcaaattc tccttattta aaagtaagaa gccacggcac
    17581 cgctcaaatt cattcagtga tgaaagagag ttctctggac cttccacccc gacggggacg
    17641 ctggagtttg aaggtgggga agtgtctctg gaaggtggga aagttaaagg gaaacacggg
    17701 aagctgaaat tcggtacctt tggtggattg gggtcaaaga gcaaaggtca ttatgaggtg
    17761 actgggagcg atgatgagac aggcaagtta caggggagtg gggtgtccct ggcctctaag
    17821 aagtcccgac tgtcctcctc ttctagcaat gacagtggga ataaggttgg catccagctt
    17881 cccgaggtgg agctgtcagt ttccacaaag aaagagtagc aggcctttgt atgtgtgtac
    17941 atatatatat atataacaaa acatcagcct tgggtggtgt gttcctatat aaactccaaa
    18001 gggaaacaca ccgactgcct cagcaatcat gcaaagacct tgcctggccc ggtggcaagc
    18061 gctgaaaaac cgaccgcctg taggctcctg gaactataca gataggtaaa gagttccaag
    18121 ttcgtccagc ccatgtgcaa agtcaacagt atttgcctta agatttcata tatatatatt
    18181 tttttgcatt gactgctgag agctcctgtt tactaagcaa gcttttgtgt ttattatcct
    18241 catttttact gaacattgtt agttttgggg taatggaaac ccactttttc attgtaatga
    18301 ctttgggggc ttttgttagt aagggtgggt ggggtgatgg gttgcagacg gaggtcaggt
    18361 cttcctcttt cctgagactg gatctgttca aacagcaaac gcccacagat ggcccagagg
    18421 tggtggtagt cagggtgtgt gggtgttttt agggttcttt agtgttgttt ctttcaccca
    18481 ggggtggtgg tcccagccag tttggtgctg acggtgagag gaaattagaa tctgtttgca
    18541 aattgtccaa cccaccccct caacatgagg ggcttccatt ttctgtgttt tgtaagggaa
    18601 ctgtttcctt catgccgcca tgttcctgat attagttctg atttcttttt aacaaatgtt
    18661 atcatgatta agaaaatttc cagcacttta atggccaatt aactgagaat gtaagaaaat
    18721 tgatgctgta caaggcaaat aaagctgttt attaaccttg a
//
