LOCUS       XM_047417103            9541 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ALF transcription elongation factor 4
            (AFF4), transcript variant X3, mRNA.
ACCESSION   XM_047417103
VERSION     XM_047417103.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000005.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9541
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
     gene            1..9541
                     /gene="AFF4"
                     /gene_synonym="AF5Q31; CHOPS; MCEF"
                     /note="ALF transcription elongation factor 4; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 27 ESTs, 1453 long SRA reads, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 55 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:27125"
                     /db_xref="HGNC:HGNC:17869"
                     /db_xref="MIM:604417"
     CDS             473..3877
                     /gene="AFF4"
                     /gene_synonym="AF5Q31; CHOPS; MCEF"
                     /codon_start=1
                     /product="AF4/FMR2 family member 4 isoform X2"
                     /protein_id="XP_047273059.1"
                     /db_xref="GeneID:27125"
                     /db_xref="HGNC:HGNC:17869"
                     /db_xref="MIM:604417"
                     /translation="MNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSK
                     EDKLSSRIQSMLGNYDEMKDFIGDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGS
                     HQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSG
                     SSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDA
                     NWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYS
                     SQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKESQQSNFGTGEQK
                     RYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGA
                     DNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLN
                     KVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQ
                     KGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASS
                     MPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDS
                     DESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDR
                     YPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHK
                     NEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTE
                     HGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSS
                     SSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYL
                     DAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVL
                     CLRCESLLYLRLFKLKKENALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSP
                     KLSPGNSGNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLS
                     KEQKEFFAELDKVMGPLIFNASIMTDLVRYTRQGLHWLRQDAKLIS"
ORIGIN      
        1 gtcagtcaca gccctggctg caggagtcca gctgccgtcg ccgccgccag cggacggggc
       61 ggggatcctg gtgccaggtc ttcgttaacc cgcccccgcc gcctcagtca gctgtcccag
      121 cccgggcccg accgtcatgg agcggtgcgg ggcctacgcc tgttccgtgt gaggcgcatc
      181 gctgccgccg ccgccgacgc cgccttcgtt tgtcgaggcc tccggaaccc ccgccgcctc
      241 ccggagcccc tcgcccttgg cagcctgtca ccgccccctg ggcgggctcg aatgcgcgtc
      301 cggtgaaggt gcaggcccgg cgccgccact gccgcagcca ggagatggtt cgggcctagc
      361 ggagccggga ctggagggaa tctagagcaa cagcaaagct gaggtcaaac taccgtaagg
      421 atggacacca aggaagctgt gtttgggaca aaaagaaatc aagataagca acatgaaccg
      481 tgaagaccgg aatgtgctgc gtatgaaaga acgggaaagg cggaatcagg aaattcagca
      541 gggcgaagac gccttcccac ctagctctcc tctctttgca gagccataca aagttactag
      601 caaagaagat aagttatcaa gtcgtattca gagtatgctt ggaaactacg atgaaatgaa
      661 ggatttcata ggagacagat ctataccaaa gcttgttgca attcccaagc ctacagtacc
      721 accatcagca gatgaaaaat ctaacccaaa tttctttgaa cagagacatg gaggctctca
      781 tcagagtagc aaatggactc cagtaggacc cgcacccagc acttctcagt ctcagaaacg
      841 gtcctcaggc ttacagagtg gacatagtag ccagcggacc agcgcaggta gcagtagtgg
      901 cactaacagt agtggtcaga ggcacgaccg tgagtcatat aacaatagtg ggagcagtag
      961 ccggaaaaaa ggccagcatg gatcagaaca ctccaaatca cgttcttcca gccctggaaa
     1021 accccaggct gtttcttcat taaactctag tcattccagg tctcatggga atgatcacca
     1081 tagcaaggaa catcaacgct ccaaatcacc tcgggaccct gatgcaaact gggattctcc
     1141 ttcccgtgta cctttttcaa gtgggcagca ctcaactcaa tctttcccac cctcattgat
     1201 gtcaaagtcc aattcaatgt tacagaaacc cactgcctat gtgcggccca tggacggaca
     1261 ggagtccatg gaaccaaagc tgtcctctga gcactacagc agccaatccc atggcaacag
     1321 catgactgag ctgaagccca gcagcaaagc acatctcacc aagctgaaaa taccttccca
     1381 accactggat gcatcagctt ctggtgatgt gagctgtgtg gatgaaatcc taaaagagtc
     1441 tcagcagtcc aattttggca ctggagaaca aaaaagatat aatccttcta aaacttcaaa
     1501 tgggcaccag tctaaatcta tgttaaaaga tgacttaaaa ctaagcagca gtgaagacag
     1561 tgatggggaa caggattgtg ataagacaat gccgaggagt acaccaggaa gtaactctga
     1621 accttcacac cataatagtg aaggagcaga taactccagg gatgattcta gtagccacag
     1681 tggatctgaa agcagctctg gatctgactc agagagtgaa agtagttcca gtgacagtga
     1741 ggcaaatgag ccatcccaga gtgcatctcc cgagcctgaa cccccgccaa caaacaaatg
     1801 gcaacttgat aattggctga ataaagtgaa cccacataaa gtgtcacccg cctcttcagt
     1861 ggacagtaac atcccatcat ctcaaggcta caaaaaggaa ggccgagagc agggcactgg
     1921 gaatagctac actgatacaa gtggacctaa agaaacgagt tccgctactc cgggacgaga
     1981 ctccaaaacc atccaaaagg gatcagaaag tgggcgtggg aggcagaaat ctcctgcaca
     2041 gagtgacagc acaacacaga gaagaactgt aggcaaaaaa caacccaaaa aggctgagaa
     2101 ggcagctgct gaagagcctc gtggaggcct gaagatagaa agtgaaaccc ctgtagactt
     2161 ggctagcagc atgccctcca gcagacacaa agcagccacc aaaggctcaa ggaaacccaa
     2221 tataaagaag gagtctaagt cttcccctcg acctacagca gagaaaaaga aatataagtc
     2281 aacaagtaaa tcttcccaga aatcaaggga aatcatagaa acagatacct catcctcaga
     2341 ttcagatgaa agtgagagcc ttcctccttc ctcacaaact cctaagtacc ccgagagcaa
     2401 taggactcct gttaaaccct cctcagtgga ggaagaagat agcttttttc ggcaacgaat
     2461 gttctctcct atggaagaga aggaacttct ttcacccctc agtgagcctg atgacaggta
     2521 cccacttatt gtgaagattg acctgaatct tttgactaga ataccaggaa agccttacaa
     2581 agaaacagag ccgcccaagg gggaaaagaa aaatgtgcca gaaaagcaca cgagagaggc
     2641 tcagaaacaa gcctcagaaa aagtttccaa caaaggcaag aggaagcata agaatgaaga
     2701 tgataaccga gccagtgaga gcaagaaacc caaaacggag gacaagaatt cagcaggcca
     2761 taagccatcc agcaacagag agtcatctaa gcagagtgct gcaaaagaaa aggatttgtt
     2821 gccttctccc gctgggcctg ttccttcaaa agatccaaaa acagagcatg gctctcggaa
     2881 gaggactatt agtcagtctt cttccttaaa gtcaagcagt aacagcaaca aggagacgag
     2941 tggcagcagc aaaaacagtt cctccacatc aaagcagaag aagaccgaag ggaagacttc
     3001 cagtagctcc aaggaggtta aggaaaaggc tccaagtagc tcctctaact gtcctccatc
     3061 tgcaccaact cttgattctt ctaagcctcg gagaacaaag cttgtctttg atgacagaaa
     3121 ttattcagca gaccattatt tacaagaagc aaaaaagcta aagcacaatg cagatgcatt
     3181 gtctgatagg tttgagaaag ctgtatacta tcttgatgct gtggtatctt tcattgaatg
     3241 tgggaatgca ttagagaaga atgctcagga atccaaatcc ccattcccta tgtattcaga
     3301 gacggtggat ctcatcaaat acactatgaa gctaaagaat tacttggcac cagatgctac
     3361 agctgcagat aaacgactca cagtactttg cctgcgatgc gagtctttgc tgtacctgag
     3421 gctgttcaaa ctgaagaagg aaaatgctct gaagtactca aagacactga cagagcacct
     3481 gaagaattct tataataatt ctcaagcacc atcgcctggc ttgggaagca aagctgtggg
     3541 gatgccttcc cctgtttctc caaagctgtc accaggcaat tcaggaaatt attcatctgg
     3601 ggccagtagt gcttctgcaa gtggttcttc agtgaccatt ccacagaaga tccaccagat
     3661 ggcagccagc tatgttcagg tcacatccaa cttcctctat gccaccgaaa tttgggacca
     3721 agctgaacag ctttccaaag agcaaaaaga attctttgct gaactggata aagtaatggg
     3781 ccctctcatc tttaatgcaa gcatcatgac agatctagtt cgttataccc ggcagggact
     3841 gcactggctt cgccaggatg ccaagttgat atcttgaact gaacacattc tcgttgcctc
     3901 tgattttctc cacaacactg tgtcacatca cgaaggaaaa ctgccataac ataccaccta
     3961 gtcgacacta agaatgagga atagttttct cctcgttggt tcatgtgttg ttgtttttga
     4021 taatccaaag cgatcatgtc agttggccct ttaatatttc caatgtgaaa gattatttaa
     4081 atgcttttaa atctgcagca cattgataag atggtttccg tgagctatga taagattgaa
     4141 attccagttg caattcataa ctaatgaatt gaaattttat ttattttaat ttttttaagt
     4201 tcccagattg gggctagttt aagacttagt tatttctgcc tataaattta ctctgttgaa
     4261 tatttagcat aaatttaatg tagacatttt tatttatata ccttgggagc tttattacct
     4321 aatatctttt tgtggtagct gttctaagag taagaattgg ttcgtctaaa ataaggacat
     4381 attctttcta cacctgctac ctgacctgat atttgaaatc ttaactccaa ttttattatt
     4441 gtggaattta cagttagtat taaggatatt cttctacaca tgaaaaaatc acttaaatat
     4501 gagaaaatgg cattctacat gtatgtacta tgaaatgtgt ctgatttggt atgcattatt
     4561 tcaaaaactg tgaatgtgtg ttaataacac tacagcaatc acacagtgac tatagcttgc
     4621 atttaatgca ttacaaaaga gggaggacaa actttctaga agaagcattt catgttgaag
     4681 ggtttcataa aaggacaatc ctgaacgtta cggattttat taaaaccata tgttattttt
     4741 tgttgctaat catttgacac ttaatcgaaa cagaataagt tactgtggaa aaaaggatga
     4801 tccaactcct gaggattgcc gcctgtgtgt ctttaattga ttatctttga tagttagagt
     4861 tatttttcag atttttcccc ctcatactgg attgtgatgc tctgatatga gcatgcaatg
     4921 actgatacag aaataggctg gagcttcggt gtgtgctttt gctatacagc ttacagttct
     4981 aatgcctgat gtagagatga tgaatttctc ctttttaaac ctatcttctg tttactcctt
     5041 ttgcattatg aaggccctct tcaatgatgt atgtttctga tggaatcaga aaatttcaca
     5101 ctagaaaagt gtacctaact tgattcagtg tgagctcttg ggacagggag tggagccagg
     5161 ggtagagctt aaagaagctg gctctgtaag agttgtatat caaagtacct tttgctacaa
     5221 ggtgcatata gaagtctaag ataagaaatg taccctctat actttatttt tcatgcccct
     5281 atcatgtttg gtgtgcctta aatcttacct ttaaatgaag actctatgga ttgtttacaa
     5341 atgaagtttt acactaggac cagatcgtcc atacatgatt ggtcttctac aataataatg
     5401 ttcaattctt tcattttaaa tctttcttta gggtcatata aagattagtt ctttcagaaa
     5461 agctattgct ttggtacatg acttagtcta accagttggg taatgctgct ttgaaaaata
     5521 gtttgtccct ctccccattc caaaaatgaa tccattcagt cagaaaaaaa gattatccta
     5581 ctatttgtag atgattgcta aggcttgaaa taggaaaggg gaaagaaggg atagaaaagt
     5641 ttcaagtcca gtagtgcagt gaatcctttg tgtttgagac ttttttacac ttatttctga
     5701 agttagtgaa ctttcattgt ccctgtggcc tcatatttat agagcttctt aactgttttg
     5761 tacctcagat tgtttttaga tgtcattgaa gattgagatg tacaaattat gttgaattta
     5821 acctgtttct cttggagaaa ttgcctctga tatctttcta acttaatctt agtgtgttct
     5881 aggaacagtt ttccataaga ggacaacttc tcaatgatca tgatagttat ttagtaagaa
     5941 ataatggttg ttaatcaaat acatgttatg tcttgtcctt ctctgatttt tctgacttgg
     6001 attccttaat ttgcagtgat gtcttagaaa tggaaaaagt atcctctggg ctttcagact
     6061 ttcagcaaca acagccagtg ggatacctct gagttcttgt gttctagtct cttgtatgtc
     6121 ctgaaaggca gcaggagcat ttttggggtc acactgatat tttgttaaag cagagtttcc
     6181 tgcatggttt atggtgctgc tctaatattt tctctttaaa actgtgtcaa tttttggaga
     6241 atgaattttt caaccttttc attgtggagg atttttccca caaggtagta atgggcaatg
     6301 gatcaaaatc ctatcataaa tgattgaatt ttcaatgtca tagtgtgtgg aaatactact
     6361 ccctttcctc catgtctatc ttcttagatg ttctgtcttt gtcatcatct gctccagcac
     6421 atactttgga ctcctttaca ggtgaccttc ccccctccct cctcaatagg tgtcctcagt
     6481 gttttctaag catttaaaac tgaatttgac aagtggctaa aaacttagtc tgagacttgt
     6541 acttagtata tggttaatta tagaaacaac aactatttta aacagttact ctgttgactg
     6601 ctctttatga ctacacttgt atgccaggag gcagcagcct atacaccatt agactcttta
     6661 caagcaacca acgaaccaat tgcagtggtt gcagttgtca cagtagtctt gcctgggcca
     6721 gactgggctg ggctgtggga agcattcccc ttcaggggag tttccacagc tcagcccagg
     6781 ctccagtctg gctagagagc atccagccca ttccttgcct cagtgccacc tttttctggg
     6841 caagtagcca agaagtgact ttatatgcag tgagtacttc agataaactt acagctacag
     6901 ctgccgaaga gtggagaagg ttgaccacca tttatttaat tctctagtgt aaaaacaatt
     6961 gagagcagtg tgcgtgagcc cacagacacc tgtgtttctg ggagctctgg cagtggcgga
     7021 ttcataggca cttgggctgc actttgaatg acacacttgg ctttattaga ttcactagtt
     7081 tttaaaaaat tgttgttcgt ttcttttcat taaaggttta atcagacaga tcagacagca
     7141 taattttgta tttaatgaca gaaacgttgg tacatttctt catgaatgag cttgcattct
     7201 gaagcaagag cctacaaaag gcacttgtta taaatgaaag ttctggctct agaggccagt
     7261 actctggagt ttcagagcag ccagtgattg ttccagtcag tgatgcctag ttatatagag
     7321 gaggagtaca ctgtgcactc ttctaggtgt aagggtatgc aactttggat cttaaaattc
     7381 tgtacacata cacactttat atatatgtat gtatgtatga aaacatgaaa ttagtttgtc
     7441 aaatatgtgt gtgtttagta ttttagctta gtgcaactat ttccacatta tttattaaat
     7501 tgatctaaga cactttcttg ttgacacctt gaatattaat gttcaagggt gcaatgtgta
     7561 ttcctttaga ttgttaaagc ttaattacta tgatttgtag taaattaact tttaaaatgt
     7621 atttgagccc ttctgtagtg tcgtagggct cttacagggt gggaaagatt ttaattttcc
     7681 agttgctaat tgaacagtat ggcctcatta tatattttga tttataggag tttgtgtctg
     7741 ggtcccagga acatctactg gggatgactg ttaggcagct tgtgatgatg ttttttaaaa
     7801 aacctaagta acttggggag acagagcatt tcaaacccat atagacacct atcatacctg
     7861 tatatcccct aatacatgga acataaattt catttcagct ttatgcatta atgtattgaa
     7921 gaggcaggct ttttttccag taataatact gtacatctaa ggttgctatt cagtaaaact
     7981 aatagaagag ataattattg aataccttgg aatatgtagt gagaagaggc caaatttttc
     8041 atgtttgtga gcatgtcttt cagatactcg ctaatggaga aattcacttt agacctctag
     8101 accccaaaac caagttagca agtgacaaaa agtaaattat taatagtctg taaagtggat
     8161 gctggtctta caaagctcct attcacatga accctatggt taattagaaa gaacttgctg
     8221 tctccagaaa agggaatgga aataataact atgtatcttc ttttcatgta atttggtcac
     8281 agaataaggt attcaagtta agtctaatcc aagtcttaga gatctttaag tatcctaaaa
     8341 tagcagccta agtagtcatc atgtaaagaa gttgactttc aggaatgtca gcattgacct
     8401 ctccttgcca ctgttactca gctaaacata acttgccatt cttaaaaata aaaaagctcc
     8461 cacccagaaa ctctagtgat actcagtttt gacctcttac tgcttccatg tgggacttct
     8521 tttcagcttt taaccattgg aattttctac ctgctatgtt cctctctgga aaatatcaat
     8581 ttggaaatgc tgcctttcaa atcaatgcca tgatcatcca tattgttgag tttgttgttg
     8641 gtgttccaga agtgtcccca ttttacaact ttatgcacac acctggcaaa tcattaacat
     8701 gagcattcaa cagtactggg atgggtgggg tgggggtagg gggctcacca acagaactgg
     8761 ccagttgaca ttgcctgaaa aggcaccacc tttaagggcc agttgtgggg ttggtaagca
     8821 cagttatgaa aatttctatc tagcctccgt tttgaatggt tttaagaaat tttgtatatg
     8881 gaggatggaa atgcttatat atttattgaa aatcctttta tttgaaatta aaattatttg
     8941 gtatataatt gtttgatatt tggggagggt tttggagggg agataatgtc actgataaat
     9001 taaaagcctg ttgattttgc agaaaggtac tgttagtgac tgataaggat gcctttgttt
     9061 tgtacatgaa ccaaatcttt gttttacatt tcttttatcc aaaatattta ggcatctgac
     9121 attttcaacc agaatttcaa ttatatactg tgatttttat ttgttgcaat acattacaat
     9181 ttcagaggta ctttggggct caaaagctag gatttctaag tcagtatgtg catttcacac
     9241 gataaagctg ttaatggtga gcaaagtatt atatactaac tagatttttc cacatctgta
     9301 tagtatatta tatgtatttt gtggtattga gagtatagaa agtttagagt gtcaaacatg
     9361 cgtttaatgt gtatttttaa acaaatttat ggcaattaaa atatttggag acaagggtat
     9421 cacatttcaa tttgtaaaga tctttttaac tctactgtgt cattaagatg ctttgtacaa
     9481 tgccaaacca tagttggaga aactaagttt aataaatatc aaatagattt tctgtattaa
     9541 a
//
