LOCUS       NM_001395425            3515 bp    mRNA    linear   PRI 20-OCT-2024
DEFINITION  Homo sapiens adhesion G protein-coupled receptor D2 (ADGRD2), mRNA.
ACCESSION   NM_001395425
VERSION     NM_001395425.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3515)
  AUTHORS   Hamann,J., Aust,G., Arac,D., Engel,F.B., Formstone,C.,
            Fredriksson,R., Hall,R.A., Harty,B.L., Kirchhoff,C., Knapp,B.,
            Krishnan,A., Liebscher,I., Lin,H.H., Martinelli,D.C., Monk,K.R.,
            Peeters,M.C., Piao,X., Promel,S., Schoneberg,T., Schwartz,T.W.,
            Singer,K., Stacey,M., Ushkaryov,Y.A., Vallon,M., Wolfrum,U.,
            Wright,M.W., Xu,L., Langenhan,T. and Schioth,H.B.
  TITLE     International Union of Basic and Clinical Pharmacology. XCIV.
            Adhesion G protein-coupled receptors
  JOURNAL   Pharmacol Rev 67 (2), 338-367 (2015)
   PUBMED   25713288
  REMARK    Review article
REFERENCE   2  (bases 1 to 3515)
  AUTHORS   Nordstrom,K.J., Lagerstrom,M.C., Waller,L.M., Fredriksson,R. and
            Schioth,H.B.
  TITLE     The Secretin GPCRs descended from the family of Adhesion GPCRs
  JOURNAL   Mol Biol Evol 26 (1), 71-84 (2009)
   PUBMED   18845549
REFERENCE   3  (bases 1 to 3515)
  AUTHORS   Bjarnadottir,T.K., Fredriksson,R., Hoglund,P.J., Gloriam,D.E.,
            Lagerstrom,M.C. and Schioth,H.B.
  TITLE     The human and mouse repertoire of the adhesion family of
            G-protein-coupled receptors
  JOURNAL   Genomics 84 (1), 23-33 (2004)
   PUBMED   15203201
REFERENCE   4  (bases 1 to 3515)
  AUTHORS   Vassilatis,D.K., Hohmann,J.G., Zeng,H., Li,F., Ranchalis,J.E.,
            Mortrud,M.T., Brown,A., Rodriguez,S.S., Weller,J.R., Wright,A.C.,
            Bergmann,J.E. and Gaitanaris,G.A.
  TITLE     The G protein-coupled receptor repertoires of human and mouse
  JOURNAL   Proc Natl Acad Sci U S A 100 (8), 4903-4908 (2003)
   PUBMED   12679517
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL137846.24.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN02400288 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000696331.1/ ENSP00000512565.1
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-60                AL137846.24        124631-124690
            61-191              AL137846.24        125485-125615
            192-284             AL137846.24        125790-125882
            285-348             AL137846.24        126271-126334
            349-561             AL137846.24        126690-126902
            562-1203            AL137846.24        127215-127856
            1204-1302           AL137846.24        128179-128277
            1303-1388           AL137846.24        128664-128749
            1389-1673           AL137846.24        129023-129307
            1674-1785           AL137846.24        130802-130913
            1786-1920           AL137846.24        131652-131786
            1921-2044           AL137846.24        132293-132416
            2045-2150           AL137846.24        132796-132901
            2151-2306           AL137846.24        140438-140593
            2307-2410           AL137846.24        141901-142004
            2411-2513           AL137846.24        142268-142370
            2514-2667           AL137846.24        142699-142852
            2668-2801           AL137846.24        143402-143535
            2802-2917           AL137846.24        143612-143727
            2918-3038           AL137846.24        144674-144794
            3039-3080           AL137846.24        149626-149667
            3081-3125           AL137846.24        149751-149795
            3126-3184           AL137846.24        150537-150595
            3185-3215           AL137846.24        150859-150889
            3216-3515           AL137846.24        152461-152760
FEATURES             Location/Qualifiers
     source          1..3515
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q33.3"
     gene            1..3515
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /note="adhesion G protein-coupled receptor D2"
                     /db_xref="GeneID:347088"
                     /db_xref="HGNC:HGNC:18651"
                     /db_xref="MIM:620837"
     exon            1..60
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            61..191
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            192..284
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     CDS             249..3197
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /note="G-protein coupled receptor GPR144; G
                     protein-coupled receptor PGR24; G-protein coupled receptor
                     144"
                     /codon_start=1
                     /product="adhesion G protein-coupled receptor D2
                     precursor"
                     /protein_id="NP_001382354.1"
                     /db_xref="CCDS:CCDS94480.1"
                     /db_xref="GeneID:347088"
                     /db_xref="HGNC:HGNC:18651"
                     /db_xref="MIM:620837"
                     /translation="MAPWCYCFLCLLIRSLSGTPSNSPGESRNPWAPAPVAAGEVVKT
                     AGGVCKFSGQRLSWWQAQESCEQQFGHLALQPPDGVLASRLRDPVWVGQREAPLRRPP
                     QRRARTTAVLVFDERTADRAARLRSPLPELAALTACTHVQWDCASPDPAALFSVAAPA
                     LPNALQLRAFAEPGGVVRAALVVRGQHAPFLAAFRADGRWHHVCATWEQRGGRWALFS
                     DGRRRAGARGLGAGHPVPSGGILVLGQDQDSLGGGFSVRHALSGNLTDFHLWARALSP
                     AQLHRARACAPPSEGLLFRWDPGALDVTPSLLPTVWVRLLCPVPSEECPTWNPGPRSE
                     GSELCLEPQPFLCCYRTEPYRRLQDAQSWPGQDVISRVNALANDIVLLPDPLSEVHGA
                     LSPAEASSFLGLLEHVLAMEMAPLGPAALLAVVRFLKRVVALGAGDPELLLTGPWEQL
                     SQGVVSVASLVLEEQVADTWLSLREVIGGPMALVASVQRLAPLLSTSMTSERPRMRIQ
                     HRHAGLEVRSLRLREASTRGCLFTMPGGRPEGPGHIHIPASEVRRLLRKGLSGVTVIH
                     SWFTSRVFQHTLEGPDLEPQAPASSEEANRVQRFLSTQVGSAIISSEVWDVTGEVNVA
                     MTFHLQHRAQSPLFPPHPPSPYTGGAWATTGCSVAALYLDSTACFCNHSTSFAILLQI
                     YEVQRGPEEESLLRTLSFVGCGVSFCALTTTFLLFLVAGVPKSERTTVHKNLTFSLAS
                     AEGFLMTSEWAKANEVACVAVTVAMHFLFLVAFSWMLVEGLLLWRKVVAVSMHPGPGM
                     RLYHATGWGVPVGIVAVTLAMLPHDYVAPGHCWLNVHTNAIWAFVGPVLFVLTANTCI
                     LARVVMITVSSARRRARMLSPQPCLQQQIWTQIWATVKPVLVLLPVLGLTWLAGILVH
                     LSPAWAYAAVGLNSIQGLYIFLVYAACNEEVRSALQRMAEKKVAEGPMALELPQHSPP
                     LQTRRDRLWN"
     exon            285..348
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            349..561
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            562..1203
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            1204..1302
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1388
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            1389..1673
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            1674..1785
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            1786..1920
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            1921..2044
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            2045..2150
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            2151..2306
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            2307..2410
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            2411..2513
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            2514..2667
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            2668..2801
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            2802..2917
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            2918..3038
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            3039..3080
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            3081..3125
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            3126..3184
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            3185..3215
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     exon            3216..3515
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3496..3501
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /note="hexamer: AATAAA"
     polyA_site      3515
                     /gene="ADGRD2"
                     /gene_synonym="GPR144; PGR24"
                     /note="major polyA site"
ORIGIN      
        1 agtccccgca gatgcctcgc agacggtgaa cggccacagg cgccaggcca gccatagcgg
       61 ggaccctgag ctctgtttcg cccctctctg gccagcgact gctgctgcct ccccctctcc
      121 cagctctcca gggcgacagt gtttccctgc ttcggtcctg aaggggctcc tggagaccat
      181 cttttgtgca atccaagttg gcctgcctgt gacccctgct gtctgtcacc tgctccgttg
      241 gatccaggat ggcaccgtgg tgctactgtt tcctctgcct cctgatcagg agtctctctg
      301 ggaccccctc caactcccca ggtgaatcaa ggaacccttg ggccccagcc cccgtggccg
      361 ccggcgaggt ggtgaagact gcaggtgggg tgtgcaagtt ctctggacag cgactgagct
      421 ggtggcaggc ccaagagtcc tgcgagcagc agtttggcca cttggcactg cagccccctg
      481 atggggttct tgcttcacgg ctgcgcgatc cggtctgggt gggccaaaga gaggcccctc
      541 tgcggagacc cccacagagg cgtgcgcgca ccaccgccgt gctggtgttc gacgagagga
      601 cggctgaccg ggcggcgcgg ctgcggagcc ctctgcctga gctggcagcg ctgaccgcgt
      661 gtactcacgt gcagtgggac tgtgcctcgc ccgaccccgc agcgctcttc tccgttgccg
      721 cgcccgcgct gcccaacgcg ctgcagctgc gcgccttcgc cgagccgggg ggcgtcgtgc
      781 gcgctgcgct ggtggtgcgt gggcagcacg cgcccttcct cgcagccttc cgcgccgacg
      841 gccgctggca ccatgtgtgc gccacgtggg agcagcgggg cgggcgctgg gcgctgttct
      901 ccgatgggag gcggcgcgct ggggcgcggg ggctgggcgc cggccacccg gtgccgtccg
      961 gcggcatcct ggtgctgggc caggatcagg actctctggg cggtggcttc tcggtgcgtc
     1021 acgccctcag cggcaacctc accgacttcc acctgtgggc gcgggcgctg agccccgctc
     1081 agctgcaccg ggcacgggcc tgcgcgccgc cctcagaggg cctgctcttc cgctgggacc
     1141 cgggcgccct ggacgtcacg ccctcgctgc tgcccactgt gtgggtgcgc cttctctgtc
     1201 ccgtgccctc cgaggagtgc cctacgtgga acccgggacc tcgcagtgag ggctctgagc
     1261 tctgcctgga gccgcagccc ttcctctgct gctaccggac agagccctat cgtcggctgc
     1321 aggatgccca gtcgtggcct ggccaggatg ttatcagccg agtcaatgcc ttggccaacg
     1381 acattgtgct cctcccggac cccctctccg aagtccatgg ggccctgtcc ccagcggagg
     1441 cctccagctt cctgggcctt ctggagcatg tcctggcgat ggagatggct cccctggggc
     1501 cggccgcact gctggctgtt gtccgcttcc tgaagagggt ggtggccctc ggggctgggg
     1561 acccagagct gttgttgaca ggcccctggg agcagctgag ccaaggcgtt gtatctgtgg
     1621 ccagcctggt cctggaggag caggtggctg acacatggct ctccctccgt gaagtgattg
     1681 gtgggcctat ggccctggtg gcgagtgtgc agcgcctggc acccctgctg agcacctcaa
     1741 tgacctcaga gcggccccga atgcgcatcc agcaccgcca tgctggcctg gaggtgcgga
     1801 gcttacgctt gagggaggcc agcacgaggg gctgcttatt cacaatgcct ggtgggcgtc
     1861 cagaggggcc cggccatatc cacattcctg cgagtgaagt gaggcgactc ctcaggaaag
     1921 gcctctctgg agtcaccgtg atccacagct ggttcacctc cagagtcttc cagcacaccc
     1981 tagagggacc ggacctagag ccccaggccc ctgccagctc agaggaggca aacagggtgc
     2041 agaggttcct aagcacccag gtggggtcag ccatcatctc ctctgaagtg tgggacgtca
     2101 ctggagaggt caacgtggcc atgacctttc atctccagca ccgggcccag agccccctgt
     2161 tccctcccca tcccccaagc ccatatacag ggggtgcctg ggccaccaca ggctgctccg
     2221 tggctgccct gtacctggac tccaccgcct gcttctgcaa ccacagcacc agctttgcca
     2281 tcctgctgca aatctatgaa gtacagagag gccctgagga ggagtcgctg ctgaggactc
     2341 tgtcatttgt gggctgtggc gtgtccttct gcgccctcac caccaccttc ttgctcttcc
     2401 tggtggccgg ggtccccaag tcagagcgaa ccacagtcca caagaacctc accttctccc
     2461 tggcctctgc cgagggcttc ctcatgacca gcgagtgggc caaggccaat gaggtggcat
     2521 gtgtggctgt cacagtcgca atgcacttcc tctttctggt ggcattctcc tggatgctgg
     2581 tggaggggct gctgctgtgg aggaaggtgg tagctgtgag catgcacccg ggcccaggca
     2641 tgcggctcta ccacgccaca ggctggggcg tgcctgtggg catcgtggcg gtcaccctgg
     2701 ccatgctccc ccatgactac gtggcccccg gacattgctg gctcaatgtg cacacaaatg
     2761 ccatctgggc cttcgtgggg cctgtgctct tcgtgctgac tgccaacacc tgcatcctgg
     2821 cccgtgtggt aatgatcacc gtgtccagtg cccgccgccg tgcccgcatg ttgagcccac
     2881 agccctgcct gcagcagcag atctggaccc agatatgggc cacggtgaag cccgtgctgg
     2941 tcctgctgcc cgtcctaggc ctgacctggc tggcaggcat cctggtgcac ctgagccccg
     3001 cctgggccta cgctgccgtg ggcctcaact ccatccaggg gctgtacatc ttcctggttt
     3061 atgctgcctg caatgaggag gtgcggagcg ccctgcagag gatggctgag aagaaggtgg
     3121 ccgagggacc tatggcccta gaactccctc agcattctcc tccattgcaa acccggagag
     3181 acaggctgtg gaactgacag cgttcaaagc ttcaggtttc tagagagtgg ctgggaaact
     3241 cgtcgccaaa ccctgcccag ctcagctctg ctgggacccc agaccccaga acggcgcagc
     3301 gggagtccct gagccccaac agcggcccca gctcccgtgg cctcagcctc tggctttccc
     3361 taaaggactg tgggcctcag ccccctgttc ccctagccca ccaggtcccc aggctctttc
     3421 ccccagtctt tgcctatctg tgatctgctc cttcccccat gctccgaagt tccaacgggc
     3481 tctgccgtgt ctggtaataa ataggactgt tgggc
//
