LOCUS       XM_047434904            2239 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin
            type 1 motif 4 (ADAMTS4), transcript variant X1, mRNA.
ACCESSION   XM_047434904
VERSION     XM_047434904.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2239
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..2239
                     /gene="ADAMTS4"
                     /gene_synonym="ADAMTS-2; ADAMTS-4; ADMP-1"
                     /note="ADAM metallopeptidase with thrombospondin type 1
                     motif 4; Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 8 ESTs, 102 long SRA reads, 2
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 17 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:9507"
                     /db_xref="HGNC:HGNC:220"
                     /db_xref="MIM:603876"
     CDS             428..2239
                     /gene="ADAMTS4"
                     /gene_synonym="ADAMTS-2; ADAMTS-4; ADMP-1"
                     /codon_start=1
                     /product="A disintegrin and metalloproteinase with
                     thrombospondin motifs 4 isoform X1"
                     /protein_id="XP_047290860.1"
                     /db_xref="GeneID:9507"
                     /db_xref="HGNC:HGNC:220"
                     /db_xref="MIM:603876"
                     /translation="MSQTGSHPGRGLAGRWLWGAQPCLLLPIVPLSWLVWLLLLLLAS
                     LLPSARLASPLPREEEIVFPEKLNGSVLPGSGAPARLLCRLQAFGETLLLELEQDSGV
                     QVEGLTVQYLGQAPELLGGAEPGTYLTGTINGDPESVASLHWDGGALLGVLQYRGAEL
                     HLQPLEGGTPNSAGGPGAHILRRKSPASGQGPMCNVKAPLGSPSPRPRRAKRFASLSR
                     FVETLVVADDKMAAFHGAGLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGE
                     EGPQVGPSAAQTLRSFCAWQRGLNTPEDSDPDHFDTAILFTRQDLCGVSTCDTLGMAD
                     VGTVCDPARSCAIVEDDGLQSAFTAAHELGHVFNMLHDNSKPCISLNGPLSTSRHVMA
                     PVMAHVDPEEPWSPCSARFITDFLDNGYGHCLLDKPEAPLHLPVTFPGKDYDADRQCQ
                     LTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQTKHSPWADGTPCGPAQACMGGRCLH
                     MDQLQDFNIPQAGGWGPWGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRF
                     RSCNTEDCPTGSGGRWDPLFPGQLLGLCPGPMHPCWL"
ORIGIN      
        1 gggagaaccc acagggagac ccacagacac atatgcacga gagagacaga ggaggaaaga
       61 gacagagaca aaggcacagc ggaagaaggc agagacaggg caggcacaga agcggcccag
      121 acagagtcct acagagggag aggccagaga agctgcagaa gacacaggca gggagagaca
      181 aagatccagg aaaggagggc tcaggaggag agtttggaga agccagaccc ctgggcacct
      241 ctcccaagcc caaggactaa gttttctcca tttcctttaa cggtcctcag cccttctgaa
      301 aactttgcct ctgaccttgg caggagtcca agcccccagg ctacagagag gagctttcca
      361 aagctagggt gtggaggact tggtgcccta gacggcctca gtccctccca gctgcagtac
      421 cagtgccatg tcccagacag gctcgcatcc cgggaggggc ttggcagggc gctggctgtg
      481 gggagcccaa ccctgcctcc tgctccccat tgtgccgctc tcctggctgg tgtggctgct
      541 tctgctactg ctggcctctc tcctgccctc agcccggctg gccagccccc tcccccggga
      601 ggaggagatc gtgtttccag agaagctcaa cggcagcgtc ctgcctggct cgggcgcccc
      661 tgccaggctg ttgtgccgct tgcaggcctt tggggagacg ctgctactag agctggagca
      721 ggactccggt gtgcaggtcg aggggctgac agtgcagtac ctgggccagg cgcctgagct
      781 gctgggtgga gcagagcctg gcacctacct gactggcacc atcaatggag atccggagtc
      841 ggtggcatct ctgcactggg atgggggagc cctgttaggc gtgttacaat atcggggggc
      901 tgaactccac ctccagcccc tggagggagg cacccctaac tctgctgggg gacctggggc
      961 tcacatccta cgccggaaga gtcctgccag cggtcaaggt cccatgtgca acgtcaaggc
     1021 tcctcttgga agccccagcc ccagaccccg aagagccaag cgctttgctt cactgagtag
     1081 atttgtggag acactggtgg tggcagatga caagatggcc gcattccacg gtgcggggct
     1141 aaagcgctac ctgctaacag tgatggcagc agcagccaag gccttcaagc acccaagcat
     1201 ccgcaatcct gtcagcttgg tggtgactcg gctagtgatc ctggggtcag gcgaggaggg
     1261 gccccaagtg gggcccagtg ctgcccagac cctgcgcagc ttctgtgcct ggcagcgggg
     1321 cctcaacacc cctgaggact cggaccctga ccactttgac acagccattc tgtttacccg
     1381 tcaggacctg tgtggagtct ccacttgcga cacgctgggt atggctgatg tgggcaccgt
     1441 ctgtgacccg gctcggagct gtgccattgt ggaggatgat gggctccagt cagccttcac
     1501 tgctgctcat gaactgggtc atgtcttcaa catgctccat gacaactcca agccatgcat
     1561 cagtttgaat gggcctttga gcacctctcg ccatgtcatg gcccctgtga tggctcatgt
     1621 ggatcctgag gagccctggt ccccctgcag tgcccgcttc atcactgact tcctggacaa
     1681 tggctatggg cactgtctct tagacaaacc agaggctcca ttgcatctgc ctgtgacttt
     1741 ccctggcaag gactatgatg ctgaccgcca gtgccagctg accttcgggc ccgactcacg
     1801 ccattgtcca cagctgccgc cgccctgtgc tgccctctgg tgctctggcc acctcaatgg
     1861 ccatgccatg tgccagacca aacactcgcc ctgggccgat ggcacaccct gcgggcccgc
     1921 acaggcctgc atgggtggtc gctgcctcca catggaccag ctccaggact tcaatattcc
     1981 acaggctggt ggctggggtc cttggggacc atggggtgac tgctctcgga cctgtggggg
     2041 tggtgtccag ttctcctccc gagactgcac gaggcctgtc ccccggaatg gtggcaagta
     2101 ctgtgagggc cgccgtaccc gcttccgctc ctgcaacact gaggactgcc caactggctc
     2161 aggtggtaga tgggaccccc tgttccccgg acagctcctc ggtctgtgtc cagggccgat
     2221 gcatccatgc tggctgtga
//
