LOCUS       XM_017021973            6611 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin
            type 1 motif 17 (ADAMTS17), transcript variant X1, mRNA.
ACCESSION   XM_017021973
VERSION     XM_017021973.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000015.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017021973.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6611
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
     gene            1..6611
                     /gene="ADAMTS17"
                     /gene_synonym="WMS4"
                     /note="ADAM metallopeptidase with thrombospondin type 1
                     motif 17; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 13 ESTs, 55 long SRA
                     reads, and 98% coverage of the annotated genomic feature
                     by RNAseq alignments, including 1 sample with support for
                     all annotated introns"
                     /db_xref="GeneID:170691"
                     /db_xref="HGNC:HGNC:17109"
                     /db_xref="MIM:607511"
     CDS             77..3646
                     /gene="ADAMTS17"
                     /gene_synonym="WMS4"
                     /codon_start=1
                     /product="A disintegrin and metalloproteinase with
                     thrombospondin motifs 17 isoform X1"
                     /protein_id="XP_016877462.1"
                     /db_xref="GeneID:170691"
                     /db_xref="HGNC:HGNC:17109"
                     /db_xref="MIM:607511"
                     /translation="MCDGALLPPLVLPVLLLLVWGLDPGTAVGDAAADVEVVLPWRVR
                     PDDVHLPPLPAAPGPRRRRRPRTPPAAPRARPGERALLLHLPAFGRDLYLQLRRDLRF
                     LSRGFEVEEAGAARRRGRPAELCFYSGRVLGHPGSLVSLSACGAAGGLVGLIQLGQEQ
                     VLIQPLNNSQGPFSGREHLIRRKWSLTPSPSAEAQRPEQLCKVLTEKKKPTWGRPSRD
                     WRERRNAIRLTSEHTVETLVVADADMVQYHGAEAAQRFILTVMNMVYNMFQHQSLGIK
                     INIQVTKLVLLRQRPAKLSIGHHGERSLESFCHWQNEEYGGARYLGNNQVPGGKDDPP
                     LVDAAVFVTRTDFCVHKDEPCDTVVPPAPFDVREGPGSPPWWCLGRELPEANGSQRVI
                     PDHSISKTWEGIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELGHNLGMNHDDDHSSC
                     AGRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKSKVSTCLLVTDPRSQHTVRLPHK
                     LPGMHYSANEQCQILFGMNATFCRNMEHLMCAGLWCLVEGDTSCKTKLDPPLDGTECG
                     ADKWCRAGECVSKTPIPEHVDGDWSPWGAWSMCSRTCGTGARFRQRKCDNPPPGPGGT
                     HCPGASVEHAVCENLPCPKGLPSFRDQQCQAHDRLSPKKKGLLTAVVVDDKPCELYCS
                     PLGKESPLLVADRVLDGTPCGPYETDLCVHGKCQKIGCDGIIGSAAKEDRCGVCSGDG
                     KTCHLVKGDFSHARGTVKNDLCTKVSTCVMAEAVPKCFSCYIEAAVIPAGARRIRVVE
                     DKPAHSFLALKDSGKGSINSDWKIELPGEFQIAGTTVRYVRRGLWEKISAKGPTKLPL
                     HLMVLLFHDQDYGIHYEYTVPVNRTAENQSEPEKPQDSLFIWTHSGWEGCSVQCGGGE
                     RRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRRCNLHPCQSRWVAGPWSPCSATCE
                     KGFQHREVTCVYQLQNGTHVATRPLYCPGPRPAAVQSCEGQDCLSIWEASEWSQCSAS
                     CGKGVWKRTVACTNSQGKCDASTRPRAEEACEDYSGCYEWKTGDWSTCSSTCGKGLQS
                     RVVQCMHKVTGRHGSECPALSKPAPYRQCYQEVCNDRINANTITSPRLAALTYKCTRD
                     QWTVYCRVIREKNLCQDMRWYQRCCQTCRDFYANKMRQPPPNS"
     polyA_site      6611
                     /gene="ADAMTS17"
                     /gene_synonym="WMS4"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 actccggctg gcgccgccgc ctagcgcgct cctgcttcgc cgccacggtc cgggggggct
       61 gccggtcccg ggtaccatgt gtgacggcgc cctgctgcct ccgctcgtcc tgcccgtgct
      121 gctgctgctg gtttggggac tggacccggg cacagctgtc ggcgacgcgg cggccgacgt
      181 ggaggtggtg ctcccgtggc gggtgcgccc cgacgacgtg cacctgccgc cgctgcccgc
      241 agcccccggg ccccgacggc ggcgacgccc ccgcacgccc ccagccgccc cgcgcgcccg
      301 gcccggagag cgcgccctgc tgctgcacct gccggccttc gggcgcgacc tgtaccttca
      361 gctgcgccgc gacctgcgct tcctgtcccg aggcttcgag gtggaggagg cgggcgcggc
      421 ccggcgccgc ggccgccccg ccgagctgtg cttctactcg ggccgtgtgc tcggccaccc
      481 cggctccctc gtctcgctca gcgcctgcgg cgccgccggc ggcctggttg gcctcattca
      541 gcttgggcag gagcaggtgc taatccagcc cctcaacaac tcccagggcc cattcagtgg
      601 acgagaacat ctgatcaggc gcaaatggtc cttgaccccc agcccttctg ctgaggccca
      661 gagacctgag cagctctgca aggttctaac agaaaagaag aagccgacgt ggggcaggcc
      721 ttcgcgggac tggcgggagc ggaggaacgc tatccggctc accagcgagc acacggtgga
      781 gaccctggtg gtggccgacg ccgacatggt gcagtaccac ggggccgagg ccgcccagag
      841 gttcatcctg accgtcatga acatggtata caatatgttt cagcaccaga gcctggggat
      901 taaaattaac attcaagtga ccaagcttgt cctgctacga caacgtcccg ctaagttgtc
      961 cattgggcac catggtgagc ggtccctgga gagcttctgt cactggcaga acgaggagta
     1021 tggaggagcg cgatacctcg gcaataacca ggttcccggc gggaaggacg acccgcccct
     1081 ggtggatgct gccgtgtttg tgaccaggac agatttctgt gtacacaagg atgaaccgtg
     1141 tgacactgtt gtgcccccag caccttttga tgtcagagag ggccctggaa gtcctccgtg
     1201 gtggtgtttg ggaagagagc tccccgaagc gaatggttct caaagggtga tcccagacca
     1261 cagcatcagc aaaacctggg aaggaattgc ttacttagga ggtgtgtgca gtgctaagag
     1321 gaagtgtgtg cttgccgaag acaatggtct caatttggcc tttaccatcg cccatgagct
     1381 gggccacaac ttgggcatga accacgacga tgaccactca tcttgcgctg gcaggtccca
     1441 catcatgtca ggagagtggg tgaaaggccg gaacccaagt gacctctctt ggtcctcctg
     1501 cagccgagat gaccttgaaa acttcctcaa gtcaaaagtc agcacctgct tgctagtcac
     1561 ggaccccaga agccagcaca cagtacgcct cccgcacaag ctgccgggca tgcactacag
     1621 tgccaacgag cagtgccaga tcctgtttgg catgaatgcc accttctgca gaaacatgga
     1681 gcatctaatg tgtgctggac tgtggtgcct ggtagaagga gacacatcct gcaagaccaa
     1741 gctggaccct cccctggatg gcaccgagtg tggggcagac aagtggtgcc gcgcggggga
     1801 gtgcgtgagc aagacgccca tcccggagca tgtggacgga gactggagcc cgtggggcgc
     1861 ctggagcatg tgcagccgaa catgtgggac gggagcccgc ttcaggcaga ggaaatgtga
     1921 caaccccccc cctgggcctg gaggcacaca ctgcccgggt gccagtgtag aacatgcggt
     1981 ctgcgagaac ctgccctgcc ccaagggtct gcccagcttc cgggaccagc agtgccaggc
     2041 acacgaccgg ctgagcccca agaagaaagg cctgctgaca gccgtggtgg ttgacgataa
     2101 gccatgtgaa ctctactgct cgcccctcgg gaaggagtcc ccactgctgg tggccgacag
     2161 ggtcctggac ggtacaccct gcgggcccta cgagactgat ctctgcgtgc acggcaagtg
     2221 ccagaaaatc ggctgtgacg gcatcatcgg gtctgcagcc aaagaggaca gatgcggggt
     2281 ctgcagcggg gacggcaaga cctgccactt ggtgaagggc gacttcagcc acgcccgggg
     2341 gacagttaag aatgatctct gtacgaaggt atccacatgt gtgatggcag aggctgttcc
     2401 caagtgtttc tcatgttata tcgaagctgc cgtcattcct gctggagctc ggaggatccg
     2461 tgtggtggag gataaacctg cccacagctt tctggctctc aaagactcgg gtaaggggtc
     2521 catcaacagt gactggaaga tagagctccc cggagagttc cagattgcag gcacaactgt
     2581 tcgctatgtg agaagggggc tgtgggagaa gatctctgcc aagggaccaa ccaaactacc
     2641 gctgcacttg atggtgttgt tatttcacga ccaagattat ggaattcatt atgaatacac
     2701 tgttcctgta aaccgcactg cggaaaatca aagcgaacca gaaaaaccgc aggactcttt
     2761 gttcatctgg acccacagcg gctgggaagg gtgcagtgtg cagtgcggcg gaggggagcg
     2821 cagaaccatc gtctcgtgta cacggattgt caacaagacc acaactctgg tgaacgacag
     2881 tgactgccct caagcaagcc gcccagagcc ccaggtccga aggtgcaact tgcacccctg
     2941 ccagtcacgg tgggtggcag gcccgtggag cccctgctcg gcgacctgtg agaaaggctt
     3001 ccagcaccgg gaggtgacct gcgtgtacca gctgcagaac ggcacacacg tcgctacgcg
     3061 gcccctctac tgcccgggcc cccggccggc ggcagtgcag agctgtgaag gccaggactg
     3121 cctgtccatc tgggaggcgt ctgagtggtc acagtgctct gccagctgtg gtaaaggggt
     3181 gtggaaacgg accgtggcgt gcaccaactc acaagggaaa tgcgacgcat ccacgaggcc
     3241 gagagccgag gaggcctgcg aggactactc aggctgctac gagtggaaaa ctggggactg
     3301 gtctacgtgc tcgtcgacct gcgggaaggg cctgcagtcc cgggtggtgc agtgcatgca
     3361 caaggtcaca gggcgccacg gcagcgagtg ccccgccctc tcgaagcctg ccccctacag
     3421 acagtgctac caggaggtct gcaacgacag gatcaacgcc aacaccatca cctccccccg
     3481 ccttgctgct ctgacctaca aatgcacacg agaccagtgg acggtatatt gccgggtcat
     3541 ccgagaaaag aacctctgcc aggacatgcg gtggtaccag cgctgctgcc agacctgcag
     3601 ggacttctat gcaaacaaga tgcgccagcc accgccgaac tcgtgacacg cagtcccaag
     3661 ggtcgctcaa agctcagact caggtctgaa acccacccac ccgcaagcct accagccttg
     3721 tggccacgcc cccacccggc tgccacaaga atccaactac atagaacatg agcgtggact
     3781 tggcgtttgc cattagtgct tccgtactta atatattgtt aacagccact ggctggcttt
     3841 ctacagtgag gagaaagtag gcatgagtca caaagtaact tcaatttcta ggatttcagg
     3901 tacctcgaag ggaagcacct ctggcagaca accgtcaaga gagagacatc atttagtgtt
     3961 cttgtcttga ctcgcttttg acatttgaat ttccagtgct tggtatatca tggaggaaac
     4021 atccccaaaa cgagacatgc tagaaaaggc tttattctga aagccggcga caccatggag
     4081 ggaggggcag gtgttggtga gcctctgccc gtggcttctc tggggagggc cgggctgctt
     4141 agcacacgtt tctctccatc taccttcttg accacatgag aaccaggacg ttgcctccat
     4201 gcccgtctct gagaacatag tctctaaatc ctaggtgttg ccttggaagt ctcgtgcgtg
     4261 gagtgtaaat ctatatatgc cagcgaggac agcagtgcca cgcagttcat accacccgca
     4321 tgggaagaat gttccaagag agtctgggtt tggggaagca tctaattttc agagctctgc
     4381 tgtccaccgt gtagggaaac agaagggcct ctcttcaagg tgctgtgaca taagaaacgg
     4441 taattgcggt gatggggttg cttcctaagg caaaggtaag cttgggccag cttcactggg
     4501 gcggatgggc acctgccccg ccttccggga acatccactc tggcctgcac ttcctaaagc
     4561 tttgtacctt agagatgctg taccacatcc cagtggcttt ctaccgaccg tggccattta
     4621 tctgaaggta agacgacatt tgggacctct gaggacacaa gcccaggcct aggatctgta
     4681 gagcaaggcc tgactgctct atcctggcac ggagcagcct gatgtgccag gaccagggga
     4741 ggaacgccat ctggctggca ctgctgcaca cccgccgagc cttcctgtag ccccagactt
     4801 tgtggtaccc attatcatca cgcctgtcat cattgaccca tcttcttggt ggggcaagga
     4861 tgatgcatga tgaaggaagg tccttccccc ctgcagcccc cttacgcctg gcagcagaca
     4921 agcagagtgg cctctttgag agcacagagg atggtagcac cctacctgca aggaggccgg
     4981 gcagggaccc tagatgccag gaggcctgtt ttgctcacca acttggtggg catttcatgg
     5041 gtgcttatgt tctaggactt taccgtaaat aacacctcct ccctgatttc agacggaagg
     5101 tctcacttgg acttccatgg gatcatctcc ctgtgcttct tgatttattg gtgctgtgtt
     5161 tctgtgtttt gttttgttac atgtcacaac cgtagagtta gcttaaatca gaaagaagcc
     5221 tctctgcctt ctccaccctg tcttacgagc tgtgtttttg tttttactac cctagaggca
     5281 gagaagcggt agggatgtca gggaatttac tcacttccac ttgaatcaac gagaagtgtt
     5341 gagaaacttc cgtgggtgct ctgtggaaag aaccgagggt gtcaggatgg agcggcccac
     5401 cctcgccccg cggcctgcgc agactgctgt cctccccttc aggcctggcc accagcagac
     5461 tcccatgaat tcccattttc acaaagccct caaaattttg ggggcgctga ggttcaattt
     5521 tcttcatccc caaatgaact gttaattcac tgaaagacat ttagactttt gcagccaagg
     5581 agcagagccg ggcaagctca ctaaggaagc cttagcttgg tctcctgcat gggccccggg
     5641 gcctccagat atgcccactg tcaccctggc aagggcccca caccctcaga atgaaaagga
     5701 ttgattgggt tattgtcaga tacccccatt agttccccta aagtctgcat ctgcagagct
     5761 cttttagctc atctttttgt tgtcggtgtt gttttttgag acagagtctc cctctgttgc
     5821 ccaggctgga gtgcagtggc gcgatctcag ctcattgaaa gctccgcctc ccgggttcag
     5881 gccattcttc tgcctcaccc tccccagtag ctgggactac aggcgcccac caccacgccc
     5941 acctactttt ttgtattttt actagagacg gggtttcacc atgttagcca ggatggtctc
     6001 gatctcctga cctcatgatc cacccgcctc agccttccaa agtgctggga ttacaggagt
     6061 gagccaccgc gcccggcctt ttagcttatc ttgaaatcca ccagcctacc ttctgttcat
     6121 ggcacgagca gtgatttcag tgaaaccatc ataaacattc ttgttccact agatgctgat
     6181 cacagcagtg atgtttctgt gttaataccc tgtactgtcc ctcgagtact gtacctttgt
     6241 gcttgcacac gtgtcactaa cgcacgtgtt accagagtct cacgacccta cggtgctatt
     6301 tttattggtg caaaattaaa ccctctcagc tgaccgttgc tggataggat cagaatgcag
     6361 gaaaagagcc tctatggcaa tacgattgtc cttttttcgt ttcagagtca aatgtatcta
     6421 ttttccattc gttaacttgc attacatact gtacccatgg aatttttgtt ttactttttg
     6481 gggctggttt tgaaaggaaa aaaaacggaa gacaaacatt ggacgccatt atacatgaaa
     6541 attatataga aaaattaatc atttcattgg aagcaagttg aatatgtgta ataaaatgtt
     6601 tttccataac a
//
