LOCUS       XM_005254872            6410 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin
            type 1 motif 17 (ADAMTS17), transcript variant X5, mRNA.
ACCESSION   XM_005254872
VERSION     XM_005254872.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000015.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_005254872.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6410
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
     gene            1..6410
                     /gene="ADAMTS17"
                     /gene_synonym="WMS4"
                     /note="ADAM metallopeptidase with thrombospondin type 1
                     motif 17; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 16 ESTs, 62 long SRA
                     reads, 1 Protein, and 97% coverage of the annotated
                     genomic feature by RNAseq alignments, including 1 sample
                     with support for all annotated introns"
                     /db_xref="GeneID:170691"
                     /db_xref="HGNC:HGNC:17109"
                     /db_xref="MIM:607511"
     CDS             77..3445
                     /gene="ADAMTS17"
                     /gene_synonym="WMS4"
                     /codon_start=1
                     /product="A disintegrin and metalloproteinase with
                     thrombospondin motifs 17 isoform X5"
                     /protein_id="XP_005254929.1"
                     /db_xref="GeneID:170691"
                     /db_xref="HGNC:HGNC:17109"
                     /db_xref="MIM:607511"
                     /translation="MCDGALLPPLVLPVLLLLVWGLDPGTAVGDAAADVEVVLPWRVR
                     PDDVHLPPLPAAPGPRRRRRPRTPPAAPRARPGERALLLHLPAFGRDLYLQLRRDLRF
                     LSRGFEVEEAGAARRRGRPAELCFYSGRVLGHPGSLVSLSACGAAGGLVGLIQLGQEQ
                     VLIQPLNNSQGPFSGREHLIRRKWSLTPSPSAEAQRPEQLCKVLTEKKKPTWGRPSRD
                     WRERRNAIRLTSEHTVETLVVADADMVQYHGAEAAQRFILTVMNMVYNMFQHQSLGIK
                     INIQVTKLVLLRQRPAKLSIGHHGERSLESFCHWQNEEYGGARYLGNNQVPGGKDDPP
                     LVDAAVFVTRTDFCVHKDEPCDTVGIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELG
                     HNLGMNHDDDHSSCAGRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKSKVSTCLLV
                     TDPRSQHTVRLPHKLPGMHYSANEQCQILFGMNATFCRNMEHLMCAGLWCLVEGDTSC
                     KTKLDPPLDGTECGADKWCRAGECVSKTPIPEHVDGDWSPWGAWSMCSRTCGTGARFR
                     QRKCDNPPPGPGGTHCPGASVEHAVCENLPCPKGLPSFRDQQCQAHDRLSPKKKGLLT
                     AVVVDDKPCELYCSPLGKESPLLVADRVLDGTPCGPYETDLCVHGKCQKIGCDGIIGS
                     AAKEDRCGVCSGDGKTCHLVKGDFSHARGTGYIEAAVIPAGARRIRVVEDKPAHSFLA
                     LKDSGKGSINSDWKIELPGEFQIAGTTVRYVRRGLWEKISAKGPTKLPLHLMVLLFHD
                     QDYGIHYEYTVPVNRTAENQSEPEKPQDSLFIWTHSGWEGCSVQCGGGERRTIVSCTR
                     IVNKTTTLVNDSDCPQASRPEPQVRRCNLHPCQSRWVAGPWSPCSATCEKGFQHREVT
                     CVYQLQNGTHVATRPLYCPGPRPAAVQSCEGQDCLSIWEASEWSQCSASCGKGVWKRT
                     VACTNSQGKCDASTRPRAEEACEDYSGCYEWKTGDWSTCSSTCGKGLQSRVVQCMHKV
                     TGRHGSECPALSKPAPYRQCYQEVCNDRINANTITSPRLAALTYKCTRDQWTVYCRVI
                     REKNLCQDMRWYQRCCQTCRDFYANKMRQPPPNS"
     polyA_site      6410
                     /gene="ADAMTS17"
                     /gene_synonym="WMS4"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 actccggctg gcgccgccgc ctagcgcgct cctgcttcgc cgccacggtc cgggggggct
       61 gccggtcccg ggtaccatgt gtgacggcgc cctgctgcct ccgctcgtcc tgcccgtgct
      121 gctgctgctg gtttggggac tggacccggg cacagctgtc ggcgacgcgg cggccgacgt
      181 ggaggtggtg ctcccgtggc gggtgcgccc cgacgacgtg cacctgccgc cgctgcccgc
      241 agcccccggg ccccgacggc ggcgacgccc ccgcacgccc ccagccgccc cgcgcgcccg
      301 gcccggagag cgcgccctgc tgctgcacct gccggccttc gggcgcgacc tgtaccttca
      361 gctgcgccgc gacctgcgct tcctgtcccg aggcttcgag gtggaggagg cgggcgcggc
      421 ccggcgccgc ggccgccccg ccgagctgtg cttctactcg ggccgtgtgc tcggccaccc
      481 cggctccctc gtctcgctca gcgcctgcgg cgccgccggc ggcctggttg gcctcattca
      541 gcttgggcag gagcaggtgc taatccagcc cctcaacaac tcccagggcc cattcagtgg
      601 acgagaacat ctgatcaggc gcaaatggtc cttgaccccc agcccttctg ctgaggccca
      661 gagacctgag cagctctgca aggttctaac agaaaagaag aagccgacgt ggggcaggcc
      721 ttcgcgggac tggcgggagc ggaggaacgc tatccggctc accagcgagc acacggtgga
      781 gaccctggtg gtggccgacg ccgacatggt gcagtaccac ggggccgagg ccgcccagag
      841 gttcatcctg accgtcatga acatggtata caatatgttt cagcaccaga gcctggggat
      901 taaaattaac attcaagtga ccaagcttgt cctgctacga caacgtcccg ctaagttgtc
      961 cattgggcac catggtgagc ggtccctgga gagcttctgt cactggcaga acgaggagta
     1021 tggaggagcg cgatacctcg gcaataacca ggttcccggc gggaaggacg acccgcccct
     1081 ggtggatgct gccgtgtttg tgaccaggac agatttctgt gtacacaagg atgaaccgtg
     1141 tgacactgtt ggaattgctt acttaggagg tgtgtgcagt gctaagagga agtgtgtgct
     1201 tgccgaagac aatggtctca atttggcctt taccatcgcc catgagctgg gccacaactt
     1261 gggcatgaac cacgacgatg accactcatc ttgcgctggc aggtcccaca tcatgtcagg
     1321 agagtgggtg aaaggccgga acccaagtga cctctcttgg tcctcctgca gccgagatga
     1381 ccttgaaaac ttcctcaagt caaaagtcag cacctgcttg ctagtcacgg accccagaag
     1441 ccagcacaca gtacgcctcc cgcacaagct gccgggcatg cactacagtg ccaacgagca
     1501 gtgccagatc ctgtttggca tgaatgccac cttctgcaga aacatggagc atctaatgtg
     1561 tgctggactg tggtgcctgg tagaaggaga cacatcctgc aagaccaagc tggaccctcc
     1621 cctggatggc accgagtgtg gggcagacaa gtggtgccgc gcgggggagt gcgtgagcaa
     1681 gacgcccatc ccggagcatg tggacggaga ctggagcccg tggggcgcct ggagcatgtg
     1741 cagccgaaca tgtgggacgg gagcccgctt caggcagagg aaatgtgaca accccccccc
     1801 tgggcctgga ggcacacact gcccgggtgc cagtgtagaa catgcggtct gcgagaacct
     1861 gccctgcccc aagggtctgc ccagcttccg ggaccagcag tgccaggcac acgaccggct
     1921 gagccccaag aagaaaggcc tgctgacagc cgtggtggtt gacgataagc catgtgaact
     1981 ctactgctcg cccctcggga aggagtcccc actgctggtg gccgacaggg tcctggacgg
     2041 tacaccctgc gggccctacg agactgatct ctgcgtgcac ggcaagtgcc agaaaatcgg
     2101 ctgtgacggc atcatcgggt ctgcagccaa agaggacaga tgcggggtct gcagcgggga
     2161 cggcaagacc tgccacttgg tgaagggcga cttcagccac gcccggggga caggttatat
     2221 cgaagctgcc gtcattcctg ctggagctcg gaggatccgt gtggtggagg ataaacctgc
     2281 ccacagcttt ctggctctca aagactcggg taaggggtcc atcaacagtg actggaagat
     2341 agagctcccc ggagagttcc agattgcagg cacaactgtt cgctatgtga gaagggggct
     2401 gtgggagaag atctctgcca agggaccaac caaactaccg ctgcacttga tggtgttgtt
     2461 atttcacgac caagattatg gaattcatta tgaatacact gttcctgtaa accgcactgc
     2521 ggaaaatcaa agcgaaccag aaaaaccgca ggactctttg ttcatctgga cccacagcgg
     2581 ctgggaaggg tgcagtgtgc agtgcggcgg aggggagcgc agaaccatcg tctcgtgtac
     2641 acggattgtc aacaagacca caactctggt gaacgacagt gactgccctc aagcaagccg
     2701 cccagagccc caggtccgaa ggtgcaactt gcacccctgc cagtcacggt gggtggcagg
     2761 cccgtggagc ccctgctcgg cgacctgtga gaaaggcttc cagcaccggg aggtgacctg
     2821 cgtgtaccag ctgcagaacg gcacacacgt cgctacgcgg cccctctact gcccgggccc
     2881 ccggccggcg gcagtgcaga gctgtgaagg ccaggactgc ctgtccatct gggaggcgtc
     2941 tgagtggtca cagtgctctg ccagctgtgg taaaggggtg tggaaacgga ccgtggcgtg
     3001 caccaactca caagggaaat gcgacgcatc cacgaggccg agagccgagg aggcctgcga
     3061 ggactactca ggctgctacg agtggaaaac tggggactgg tctacgtgct cgtcgacctg
     3121 cgggaagggc ctgcagtccc gggtggtgca gtgcatgcac aaggtcacag ggcgccacgg
     3181 cagcgagtgc cccgccctct cgaagcctgc cccctacaga cagtgctacc aggaggtctg
     3241 caacgacagg atcaacgcca acaccatcac ctccccccgc cttgctgctc tgacctacaa
     3301 atgcacacga gaccagtgga cggtatattg ccgggtcatc cgagaaaaga acctctgcca
     3361 ggacatgcgg tggtaccagc gctgctgcca gacctgcagg gacttctatg caaacaagat
     3421 gcgccagcca ccgccgaact cgtgacacgc agtcccaagg gtcgctcaaa gctcagactc
     3481 aggtctgaaa cccacccacc cgcaagccta ccagccttgt ggccacgccc ccacccggct
     3541 gccacaagaa tccaactaca tagaacatga gcgtggactt ggcgtttgcc attagtgctt
     3601 ccgtacttaa tatattgtta acagccactg gctggctttc tacagtgagg agaaagtagg
     3661 catgagtcac aaagtaactt caatttctag gatttcaggt acctcgaagg gaagcacctc
     3721 tggcagacaa ccgtcaagag agagacatca tttagtgttc ttgtcttgac tcgcttttga
     3781 catttgaatt tccagtgctt ggtatatcat ggaggaaaca tccccaaaac gagacatgct
     3841 agaaaaggct ttattctgaa agccggcgac accatggagg gaggggcagg tgttggtgag
     3901 cctctgcccg tggcttctct ggggagggcc gggctgctta gcacacgttt ctctccatct
     3961 accttcttga ccacatgaga accaggacgt tgcctccatg cccgtctctg agaacatagt
     4021 ctctaaatcc taggtgttgc cttggaagtc tcgtgcgtgg agtgtaaatc tatatatgcc
     4081 agcgaggaca gcagtgccac gcagttcata ccacccgcat gggaagaatg ttccaagaga
     4141 gtctgggttt ggggaagcat ctaattttca gagctctgct gtccaccgtg tagggaaaca
     4201 gaagggcctc tcttcaaggt gctgtgacat aagaaacggt aattgcggtg atggggttgc
     4261 ttcctaaggc aaaggtaagc ttgggccagc ttcactgggg cggatgggca cctgccccgc
     4321 cttccgggaa catccactct ggcctgcact tcctaaagct ttgtacctta gagatgctgt
     4381 accacatccc agtggctttc taccgaccgt ggccatttat ctgaaggtaa gacgacattt
     4441 gggacctctg aggacacaag cccaggccta ggatctgtag agcaaggcct gactgctcta
     4501 tcctggcacg gagcagcctg atgtgccagg accaggggag gaacgccatc tggctggcac
     4561 tgctgcacac ccgccgagcc ttcctgtagc cccagacttt gtggtaccca ttatcatcac
     4621 gcctgtcatc attgacccat cttcttggtg gggcaaggat gatgcatgat gaaggaaggt
     4681 ccttcccccc tgcagccccc ttacgcctgg cagcagacaa gcagagtggc ctctttgaga
     4741 gcacagagga tggtagcacc ctacctgcaa ggaggccggg cagggaccct agatgccagg
     4801 aggcctgttt tgctcaccaa cttggtgggc atttcatggg tgcttatgtt ctaggacttt
     4861 accgtaaata acacctcctc cctgatttca gacggaaggt ctcacttgga cttccatggg
     4921 atcatctccc tgtgcttctt gatttattgg tgctgtgttt ctgtgttttg ttttgttaca
     4981 tgtcacaacc gtagagttag cttaaatcag aaagaagcct ctctgccttc tccaccctgt
     5041 cttacgagct gtgtttttgt ttttactacc ctagaggcag agaagcggta gggatgtcag
     5101 ggaatttact cacttccact tgaatcaacg agaagtgttg agaaacttcc gtgggtgctc
     5161 tgtggaaaga accgagggtg tcaggatgga gcggcccacc ctcgccccgc ggcctgcgca
     5221 gactgctgtc ctccccttca ggcctggcca ccagcagact cccatgaatt cccattttca
     5281 caaagccctc aaaattttgg gggcgctgag gttcaatttt cttcatcccc aaatgaactg
     5341 ttaattcact gaaagacatt tagacttttg cagccaagga gcagagccgg gcaagctcac
     5401 taaggaagcc ttagcttggt ctcctgcatg ggccccgggg cctccagata tgcccactgt
     5461 caccctggca agggccccac accctcagaa tgaaaaggat tgattgggtt attgtcagat
     5521 acccccatta gttcccctaa agtctgcatc tgcagagctc ttttagctca tctttttgtt
     5581 gtcggtgttg ttttttgaga cagagtctcc ctctgttgcc caggctggag tgcagtggcg
     5641 cgatctcagc tcattgaaag ctccgcctcc cgggttcagg ccattcttct gcctcaccct
     5701 ccccagtagc tgggactaca ggcgcccacc accacgccca cctacttttt tgtattttta
     5761 ctagagacgg ggtttcacca tgttagccag gatggtctcg atctcctgac ctcatgatcc
     5821 acccgcctca gccttccaaa gtgctgggat tacaggagtg agccaccgcg cccggccttt
     5881 tagcttatct tgaaatccac cagcctacct tctgttcatg gcacgagcag tgatttcagt
     5941 gaaaccatca taaacattct tgttccacta gatgctgatc acagcagtga tgtttctgtg
     6001 ttaataccct gtactgtccc tcgagtactg tacctttgtg cttgcacacg tgtcactaac
     6061 gcacgtgtta ccagagtctc acgaccctac ggtgctattt ttattggtgc aaaattaaac
     6121 cctctcagct gaccgttgct ggataggatc agaatgcagg aaaagagcct ctatggcaat
     6181 acgattgtcc ttttttcgtt tcagagtcaa atgtatctat tttccattcg ttaacttgca
     6241 ttacatactg tacccatgga atttttgttt tactttttgg ggctggtttt gaaaggaaaa
     6301 aaaacggaag acaaacattg gacgccatta tacatgaaaa ttatatagaa aaattaatca
     6361 tttcattgga agcaagttga atatgtgtaa taaaatgttt ttccataaca
//
