LOCUS       XM_011539300            5056 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin
            type 1 motif 14 (ADAMTS14), transcript variant X1, mRNA.
ACCESSION   XM_011539300
VERSION     XM_011539300.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000010.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011539300.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5056
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
     gene            1..5056
                     /gene="ADAMTS14"
                     /note="ADAM metallopeptidase with thrombospondin type 1
                     motif 14; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 8 ESTs, 61 long SRA reads,
                     and 99% coverage of the annotated genomic feature by
                     RNAseq alignments, including 4 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:140766"
                     /db_xref="HGNC:HGNC:14899"
                     /db_xref="MIM:607506"
     CDS             298..3468
                     /gene="ADAMTS14"
                     /codon_start=1
                     /product="A disintegrin and metalloproteinase with
                     thrombospondin motifs 14 isoform X1"
                     /protein_id="XP_011537602.1"
                     /db_xref="GeneID:140766"
                     /db_xref="HGNC:HGNC:14899"
                     /db_xref="MIM:607506"
                     /translation="MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPC
                     STDFRGRFLSHVVSGPAAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVG
                     RHSLYFNVTVFGKELHLRLRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTG
                     MPGAAVAISNCDGLAGLIRTDSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAE
                     PDGDLHNEAFGLGDLPNLLGLVGDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHG
                     KEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQ
                     VCRWAHSQQRQDPSHAEHHDHVVFLTRQDFGPSGMQGYAPVTGMCHPLRSCALNHEDG
                     FSSAFVIAHETGHVLGMEHDGQGNGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELS
                     RYLPSYDCLLDDPFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQL
                     WCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHCIWKSPEQTYGQDGGWSSWTKFGS
                     CSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQVCNSEECPGTYEDFRAQQCAKR
                     NSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSV
                     CARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPA
                     GARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTFTAMGLEWEDAVEDAKES
                     LKTSGPLPEAIAILCSATCGEGIQQRQVVCRTNANSLGHCEGDRPDTVQVCSLPACGG
                     NHQNSTVRADVWELGTPEGQWVPQSEPLHPINKISSTEPCTGDRSVFCQMEVLDRYCS
                     IPGYHRLCCVSCIKKASGPNPGPDPGPTSLPPFSTPGSPLPGPQDPADAAEPPGKPTG
                     SEDHQHGRATQLPGALDTSSPGTQHPFAPETPIPGASWSISPTTPGGLPWGWTQTPTP
                     VPEDKGQPGEDLRHPGTSLPAASPVT"
ORIGIN      
        1 actgcgcggg cgggctgacc gaccagccgg cagttggcac cgggtgcgct ggcgcgtcag
       61 tggccccgct ctccagccgg cagcctcgcg cgcccggagc cagcggtcca ggcggcggcg
      121 ccgcgcaggg gacccggagc aggcgggagg gaagcagcta ggcggggagg cggctgaggc
      181 ggcagcggcg gcagccagcc ggtgctccga cagcccgggg cgcaccctag cctcgccgcc
      241 ctcagcctgg gacttgggga tcgggcgctt gcccagcccg cgtcccagcg cggccacatg
      301 gctccactcc gcgcgctgct gtcctacctg ctgcctttgc actgtgcgct ctgcgccgcc
      361 gcgggcagcc ggaccccaga gctgcacctc tctggaaagc tcagtgacta tggtgtgaca
      421 gtgccctgca gcacagactt tcggggacgc ttcctctccc acgtggtgtc tggcccagca
      481 gcagcctctg cagggagcat ggtagtggac acgccaccca cactaccacg acactccagt
      541 cacctccggg tggctcgcag ccctctgcac ccaggaggga ccctgtggcc tggcagggtg
      601 gggcgccact ccctctactt caatgtcact gttttcggga aggaactgca cttgcgcctg
      661 cggcccaatc ggaggttggt agtgccagga tcctcagtgg agtggcagga ggattttcgg
      721 gagctgttcc ggcagccctt acggcaggag tgtgtgtaca ctggaggtgt cactggaatg
      781 cctggggcag ctgttgccat cagcaactgt gacggattgg cgggcctcat ccgcacagac
      841 agcaccgact tcttcattga gcctctggag cggggccagc aggagaagga ggccagcggg
      901 aggacacatg tggtgtaccg ccgggaggcc gtccagcagg agtgggcaga acctgacggg
      961 gacctgcaca atgaagcctt tggcctggga gaccttccca acctgctggg cctggtgggg
     1021 gaccagctgg gcgacacaga gcggaagcgg cggcatgcca agccaggcag ctacagcatc
     1081 gaggtgctgc tggtggtgga cgactcggtg gttcgcttcc atggcaagga gcatgtgcag
     1141 aactatgtcc tcaccctcat gaatatcgta gatgagattt accacgatga gtccctgggg
     1201 gttcatataa atattgccct cgtccgcttg atcatggttg gctaccgaca gtccctgagc
     1261 ctgatcgagc gcgggaaccc ctcacgcagc ctggagcagg tgtgtcgctg ggcacactcc
     1321 cagcagcgcc aggaccccag ccacgctgag caccatgacc acgttgtgtt cctcacccgg
     1381 caggactttg ggccctcagg tatgcaaggg tatgcacccg tcactggcat gtgtcacccc
     1441 ctgaggagct gtgccctcaa ccatgaggat ggcttctcct cagccttcgt gatagctcat
     1501 gagaccggcc acgtgctcgg catggagcat gacggtcagg ggaatggctg tgcagatgag
     1561 accagcctgg gcagcgtcat ggcgcccctg gtgcaggctg ccttccaccg cttccattgg
     1621 tcccgctgca gcaagctgga gctcagccgc tacctcccct cctacgactg cctcctcgat
     1681 gacccctttg atcctgcctg gccccagccc ccagagctgc ctgggatcaa ctactcaatg
     1741 gatgagcagt gccgctttga ctttggcagt ggctaccaga cctgcttggc attcaggacc
     1801 tttgagccct gcaagcagct gtggtgcagc catcctgaca acccgtactt ctgcaagacc
     1861 aagaaggggc ccccgctgga tgggactgag tgtgcacccg gcaagtggtg cttcaaaggt
     1921 cactgcatct ggaagtcgcc ggagcagaca tatggccagg atggaggctg gagctcctgg
     1981 accaagtttg ggtcatgttc gcggtcatgt gggggcgggg tgcgatcccg cagccggagc
     2041 tgcaacaacc cctccccagc ctatggaggc cgcctgtgct tagggcccat gttcgagtac
     2101 caggtctgca acagcgagga gtgccctggg acctacgagg acttccgggc ccagcagtgt
     2161 gccaagcgca actcctacta tgtgcaccag aatgccaagc acagctgggt gccctacgag
     2221 cctgacgatg acgcccagaa gtgtgagctg atctgccagt cggcggacac gggggacgtg
     2281 gtgttcatga accaggtggt tcacgatggg acacgctgca gctaccggga cccatacagc
     2341 gtctgtgcgc gtggcgagtg tgtgcctgtc ggctgtgaca aggaggtggg gtccatgaag
     2401 gcggatgaca agtgtggagt ctgcgggggt gacaactccc actgcaggac tgtgaagggg
     2461 acgctgggca aggcctccaa gcaggcagga gctctcaagc tggtgcagat cccagcaggt
     2521 gccaggcaca tccagattga ggcactggag aagtcccccc accgcattgt ggtgaagaac
     2581 caggtcaccg gcagcttcat cctcaacccc aagggcaagg aagccacaag ccggaccttc
     2641 accgccatgg gcctggagtg ggaggatgcg gtggaggatg ccaaggaaag cctcaagacc
     2701 agcgggcccc tgcctgaagc cattgccatc ctgtgctctg ccacctgtgg agagggcatc
     2761 cagcagcggc aggtggtgtg caggaccaac gccaacagcc tcgggcattg cgagggggat
     2821 aggccagaca ctgtccaggt ctgcagcctg cccgcctgtg gaggaaatca ccagaactcc
     2881 acggtgaggg ccgatgtctg ggaacttggg acgccagagg ggcagtgggt gccacaatct
     2941 gaacccctac atcccattaa caagatatca tcaacggagc cctgcacggg agacaggtct
     3001 gtcttctgcc agatggaagt gctcgatcgc tactgctcca ttcccggcta ccaccggctc
     3061 tgctgtgtgt cctgcatcaa gaaggcctcg ggccccaacc ctggcccaga ccctggccca
     3121 acctcactgc cccccttctc cactcctgga agccccttac caggacccca ggaccctgca
     3181 gatgctgcag agcctcctgg aaagccaacg ggatcagagg accatcagca tggccgagcc
     3241 acacagctcc caggagctct ggatacaagc tccccaggga cccagcatcc ctttgcccct
     3301 gagacaccaa tccctggagc atcctggagc atctccccta ccacccccgg ggggctgcct
     3361 tggggctgga ctcagacacc tacgccagtc cctgaggaca aagggcaacc tggagaagac
     3421 ctgagacatc ccggcaccag cctccctgct gcctccccgg tgacatgagc tgtgccctgc
     3481 catcccactg gcacgtttac actctgtgta ctgccccgtg actcccagct cagaggacac
     3541 acatagcagg gcaggcgcaa gcacagactt cattttaaat cattcgcctt cttctcgttt
     3601 ggggctgtga tgctctttac cccacaaagc ggggtgggag gaagacaaag atcagggaaa
     3661 gccctaatcg gagatacctc agcaagctgc ccccggcggg actgaccctc tcagggcccc
     3721 tgttggtctc ccctgccaag accagggtca actattgctc cctcctcaca gaccctgggc
     3781 ctgggcaggt ctgaatcccg gctggtctgt agctagaagc tgtcagggct gcctgccttc
     3841 ccggaactgt gaggacccct gtggaggccc tgcatatttg gcccctctcc ccagaaaggc
     3901 aaagcagggc cagggtaggt gggggactgt tcacagccag gccgagagga ggggggcctg
     3961 ggaatgtggc atgaggcttc ccagctgcag ggctggaggg ggtggaacac aaggtgatcg
     4021 caggcccagc tcctggaagc caagagctcc atgcagttcc accagctgag gccaggcagc
     4081 agaggccagt ttgtctttgc tggccagaag atggtgctca tggccatact ctggccttgc
     4141 agatgtcact agtgttactt ctagtgactc cagattacag actggccccc caatctcacc
     4201 ccagcccacc agagaagggg gctcaggaca ccctggaccc caagtcctca gcatccaggg
     4261 atttccaaac tggcgctcac tccctgactc caccaggatg gcaacttcaa ttatcactct
     4321 cagcctggaa ggggactctg tgggacacag agggaacacg atttctcagg ctgtcccttc
     4381 aatcattgcc cttctccgaa gatcgctcct gctggagtcg gacatcttca tcttctacct
     4441 ggctcaagct gggccagagt gtgtggttct cccaggggtg gttggacccc aggactgagg
     4501 accagagtcc actcatagcc tggccctgga gatgacaagg gccacccagg ccaagtgccc
     4561 cagggcaggg tgccagcccc tggcctggtg ctggagtggg gaagacacac tcacccacgg
     4621 tgctgtaagg gcctgagctg tgctcagctg ccggccatgc tacctccaag ggacaggtaa
     4681 cagtcttaga tcctctggct ctcaggaagt ggcagggggt cccaggacac ctccggggtc
     4741 ttggaggatg tctcctaaac tcctgccagg tgatagaggt gcttctcact tcttccttcc
     4801 ccaaggcaaa ggggctgttc tgagccagcc tggaggaaca tgagtagtgg gcccctggcc
     4861 tgcaacccct ttggagagtg gaggtcctgg ggggctcccc gccctccccc tgttgccctc
     4921 ccctccctgg gatgctgggg cacacgcgga gtcattcctg tgagaaccag cctggcctgt
     4981 gttaaactct tgtgccttgg aaatccagat ctttaaaatt ttatgtattt attaacatcg
     5041 ccattggacc ccaaaa
//
