LOCUS       XM_011518178            3260 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin
            type 1 motif 13 (ADAMTS13), transcript variant X6, mRNA.
ACCESSION   XM_011518178
VERSION     XM_011518178.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000009.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011518178.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3260
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
     gene            1..3260
                     /gene="ADAMTS13"
                     /gene_synonym="ADAM-TS13; ADAMTS-13; C9orf8; vWF-CP;
                     VWFCP"
                     /note="ADAM metallopeptidase with thrombospondin type 1
                     motif 13; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 10 ESTs, 21 long SRA
                     reads, 1 Protein, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 7 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:11093"
                     /db_xref="HGNC:HGNC:1366"
                     /db_xref="MIM:604134"
     CDS             106..3054
                     /gene="ADAMTS13"
                     /gene_synonym="ADAM-TS13; ADAMTS-13; C9orf8; vWF-CP;
                     VWFCP"
                     /codon_start=1
                     /product="A disintegrin and metalloproteinase with
                     thrombospondin motifs 13 isoform X6"
                     /protein_id="XP_011516480.1"
                     /db_xref="GeneID:11093"
                     /db_xref="HGNC:HGNC:1366"
                     /db_xref="MIM:604134"
                     /translation="MSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRA
                     IGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQV
                     CGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRYVV
                     AGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRRYGE
                     EYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVET
                     VQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKT
                     LPPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADG
                     LEAPVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAH
                     VWTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPA
                     RWQYKLAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEP
                     CPPRWKVMSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLI
                     ADCTYRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWA
                     GPCVGQGTPSLVPHEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQEN
                     SVQSSACGRQHLEPTGTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLL
                     LWGRLTWRKMCRKLLDMTFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDM
                     QLFGPWGEIVSPSLSPATSNAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYIL
                     IRDTHSLRTTAFHGQQVLYWESESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQD
                     PQSWKGKEGT"
ORIGIN      
        1 ctggggtccc cgaagtcctt gctcccgctc ctgcggagga ggtgtggtca ccaggaggcg
       61 gcagtgcaac aaccccaggc ctgcgagaag acccagctgg agttcatgtc gcaacagtgc
      121 gccaggaccg acggccagcc gctgcgctcc tcccctggcg gcgcctcctt ctaccactgg
      181 ggtgctgctg taccacacag ccaaggggat gctctgtgca gacacatgtg ccgggccatt
      241 ggcgagagct tcatcatgaa gcgtggagac agcttcctcg atgggacccg gtgtatgcca
      301 agtggccccc gggaggacgg gaccctgagc ctgtgtgtgt cgggcagctg caggacattt
      361 ggctgtgatg gtaggatgga ctcccagcag gtatgggaca ggtgccaggt gtgtggtggg
      421 gacaacagca cgtgcagccc acggaagggc tctttcacag ctggcagagc gagagaatat
      481 gtcacgtttc tgacagttac ccccaacctg accagtgtct acattgccaa ccacaggcct
      541 ctcttcacac acttggcggt gaggatcgga gggcgctatg tcgtggctgg gaagatgagc
      601 atctccccta acaccaccta cccctccctc ctggaggatg gtcgtgtcga gtacagagtg
      661 gccctcaccg aggaccggct gccccgcctg gaggagatcc gcatctgggg acccctccag
      721 gaagatgctg acatccaggt ttacaggcgg tatggcgagg agtatggcaa cctcacccgc
      781 ccagacatca ccttcaccta cttccagcct aagccacggc aggcctgggt gtgggccgct
      841 gtgcgtgggc cctgctcggt gagctgtggg gcagggctgc gctgggtaaa ctacagctgc
      901 ctggaccagg ccaggaagga gttggtggag actgtccagt gccaagggag ccagcagcca
      961 ccagcgtggc cagaggcctg cgtgctcgaa ccctgccctc cctactgggc ggtgggagac
     1021 ttcggcccat gcagcgcctc ctgtgggggt ggcctgcggg agcggccagt gcgctgcgtg
     1081 gaggcccagg gcagcctcct gaagacattg cccccagccc ggtgcagagc aggggcccag
     1141 cagccagctg tggcgctgga aacctgcaac ccccagccct gccctgccag gtgggaggtg
     1201 tcagagccca gctcatgcac atcagctggt ggagcaggcc tggccttgga gaacgagacc
     1261 tgtgtgccag gggcagatgg cctggaggct ccagtgactg aggggcctgg ctccgtagat
     1321 gagaagctgc ctgcccctga gccctgtgtc gggatgtcat gtcctccagg ctggggccat
     1381 ctggatgcca cctctgcagg ggagaaggct ccctccccat ggggcagcat caggacgggg
     1441 gctcaagctg cacacgtgtg gacccctgcg gcagggtcgt gctccgtctc ctgcgggcga
     1501 ggtctgatgg agctgcgttt cctgtgcatg gactctgccc tcagggtgcc tgtccaggaa
     1561 gagctgtgtg gcctggcaag caagcctggg agccggcggg aggtctgcca ggctgtcccg
     1621 tgccctgctc ggtggcagta caagctggcg gcctgcagcg tgagctgtgg gagaggggtc
     1681 gtgcggagga tcctgtattg tgcccgggcc catggggagg acgatggtga ggagatcctg
     1741 ttggacaccc agtgccaggg gctgcctcgc ccggaacccc aggaggcctg cagcctggag
     1801 ccctgcccac ctaggtggaa agtcatgtcc cttggcccat gttcggccag ctgtggcctt
     1861 ggcactgcta gacgctcggt ggcctgtgtg cagctcgacc aaggccagga cgtggaggtg
     1921 gacgaggcgg cctgtgcggc gctggtgcgg cccgaggcca gtgtcccctg tctcattgcc
     1981 gactgcacct accgctggca tgttggcacc tggatggagt gctctgtttc ctgtggggat
     2041 ggcatccagc gccggcgtga cacctgcctc ggaccccagg cccaggcgcc tgtgccagct
     2101 gatttctgcc agcacttgcc caagccggtg actgtgcgtg gctgctgggc tgggccctgt
     2161 gtgggacagg gtacgcccag cctggtgccc cacgaagaag ccgctgctcc aggacggacc
     2221 acagccaccc ctgctggtgc ctccctggag tggtcccagg cccggggcct gctcttctcc
     2281 ccggctcccc agcctcggcg gctcctgccc gggccccagg aaaactcagt gcagtccagt
     2341 gcctgtggca ggcagcacct tgagccaaca ggaaccattg acatgcgagg cccagggcag
     2401 gcagactgtg cagtggccat tgggcggccc ctcggggagg tggtgaccct ccgcgtcctt
     2461 gagagttctc tcaactgcag tgcgggggac atgttgctgc tttggggccg gctcacctgg
     2521 aggaagatgt gcaggaagct gttggacatg actttcagct ccaagaccaa cacgctggtg
     2581 gtgaggcagc gctgcgggcg gccaggaggt ggggtgctgc tgcggtatgg gagccagctt
     2641 gctcctgaaa ccttctacag agaatgtgac atgcagctct ttgggccctg gggtgaaatc
     2701 gtgagcccct cgctgagtcc agccacgagt aatgcagggg gctgccggct cttcattaat
     2761 gtggctccgc acgcacggat tgccatccat gccctggcca ccaacatggg cgctgggacc
     2821 gagggagcca atgccagcta catcttgatc cgggacaccc acagcttgag gaccacagcg
     2881 ttccatgggc agcaggtgct ctactgggag tcagagagca gccaggctga gatggagttc
     2941 agcgagggct tcctgaaggc tcaggccagc ctgcggggcc agtactggac cctccaatca
     3001 tgggtaccgg agatgcagga ccctcagtcc tggaagggaa aggaaggaac ctgagggtca
     3061 ttgaacattt gttccgtgtc tggccagccc tggagggttg acccctggtc tcagtgcttt
     3121 ccaattcgaa ctttttccaa tcttaggtat ctactttaga gtcttctcca atgtccaaaa
     3181 ggctaggggg ttggaggtgg ggactctgga aaagcagccc ccatttcctc gggtaccaat
     3241 aaataaaaca tgcaggctga
//
