LOCUS       NM_001142807            2699 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens acyl-CoA oxidase like (ACOXL), transcript variant 1,
            mRNA.
ACCESSION   NM_001142807
VERSION     NM_001142807.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2699)
  AUTHORS   O'Hurley,G., Busch,C., Fagerberg,L., Hallstrom,B.M., Stadler,C.,
            Tolf,A., Lundberg,E., Schwenk,J.M., Jirstrom,K., Bjartell,A.,
            Gallagher,W.M., Uhlen,M. and Ponten,F.
  TITLE     Analysis of the Human Prostate-Specific Proteome Defined by
            Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and
            ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer
  JOURNAL   PLoS One 10 (8), e0133449 (2015)
   PUBMED   26237329
  REMARK    GeneRIF: The study identified two proteins, TMEM79 and ACOXL, with
            potential to differentiate between benign and cancerous prostatic
            glands in tissue biopsies.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2699)
  AUTHORS   Figueiredo,J.C., Hsu,L., Hutter,C.M., Lin,Y., Campbell,P.T.,
            Baron,J.A., Berndt,S.I., Jiao,S., Casey,G., Fortini,B., Chan,A.T.,
            Cotterchio,M., Lemire,M., Gallinger,S., Harrison,T.A., Le
            Marchand,L., Newcomb,P.A., Slattery,M.L., Caan,B.J., Carlson,C.S.,
            Zanke,B.W., Rosse,S.A., Brenner,H., Giovannucci,E.L., Wu,K.,
            Chang-Claude,J., Chanock,S.J., Curtis,K.R., Duggan,D., Gong,J.,
            Haile,R.W., Hayes,R.B., Hoffmeister,M., Hopper,J.L., Jenkins,M.A.,
            Kolonel,L.N., Qu,C., Rudolph,A., Schoen,R.E., Schumacher,F.R.,
            Seminara,D., Stelling,D.L., Thibodeau,S.N., Thornquist,M.,
            Warnick,G.S., Henderson,B.E., Ulrich,C.M., Gauderman,W.J.,
            Potter,J.D., White,E. and Peters,U.
  CONSRTM   CCFR; GECCO
  TITLE     Genome-wide diet-gene interaction analyses for risk of colorectal
            cancer
  JOURNAL   PLoS Genet 10 (4), e1004228 (2014)
   PUBMED   24743840
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2699)
  AUTHORS   Okada,Y., Wu,D., Trynka,G., Raj,T., Terao,C., Ikari,K., Kochi,Y.,
            Ohmura,K., Suzuki,A., Yoshida,S., Graham,R.R., Manoharan,A.,
            Ortmann,W., Bhangale,T., Denny,J.C., Carroll,R.J., Eyler,A.E.,
            Greenberg,J.D., Kremer,J.M., Pappas,D.A., Jiang,L., Yin,J., Ye,L.,
            Su,D.F., Yang,J., Xie,G., Keystone,E., Westra,H.J., Esko,T.,
            Metspalu,A., Zhou,X., Gupta,N., Mirel,D., Stahl,E.A., Diogo,D.,
            Cui,J., Liao,K., Guo,M.H., Myouzen,K., Kawaguchi,T., Coenen,M.J.,
            van Riel,P.L., van de Laar,M.A., Guchelaar,H.J., Huizinga,T.W.,
            Dieude,P., Mariette,X., Bridges,S.L. Jr., Zhernakova,A., Toes,R.E.,
            Tak,P.P., Miceli-Richard,C., Bang,S.Y., Lee,H.S., Martin,J.,
            Gonzalez-Gay,M.A., Rodriguez-Rodriguez,L., Rantapaa-Dahlqvist,S.,
            Arlestig,L., Choi,H.K., Kamatani,Y., Galan,P., Lathrop,M., Eyre,S.,
            Bowes,J., Barton,A., de Vries,N., Moreland,L.W., Criswell,L.A.,
            Karlson,E.W., Taniguchi,A., Yamada,R., Kubo,M., Liu,J.S., Bae,S.C.,
            Worthington,J., Padyukov,L., Klareskog,L., Gregersen,P.K.,
            Raychaudhuri,S., Stranger,B.E., De Jager,P.L., Franke,L.,
            Visscher,P.M., Brown,M.A., Yamanaka,H., Mimori,T., Takahashi,A.,
            Xu,H., Behrens,T.W., Siminovitch,K.A., Momohara,S., Matsuda,F.,
            Yamamoto,K. and Plenge,R.M.
  CONSRTM   RACI consortium; GARNET consortium
  TITLE     Genetics of rheumatoid arthritis contributes to biology and drug
            discovery
  JOURNAL   Nature 506 (7488), 376-381 (2014)
   PUBMED   24390342
REFERENCE   4  (bases 1 to 2699)
  AUTHORS   Speedy,H.E., Di Bernardo,M.C., Sava,G.P., Dyer,M.J., Holroyd,A.,
            Wang,Y., Sunter,N.J., Mansouri,L., Juliusson,G., Smedby,K.E.,
            Roos,G., Jayne,S., Majid,A., Dearden,C., Hall,A.G.,
            Mainou-Fowler,T., Jackson,G.H., Summerfield,G., Harris,R.J.,
            Pettitt,A.R., Allsup,D.J., Bailey,J.R., Pratt,G., Pepper,C.,
            Fegan,C., Rosenquist,R., Catovsky,D., Allan,J.M. and Houlston,R.S.
  TITLE     A genome-wide association study identifies multiple susceptibility
            loci for chronic lymphocytic leukemia
  JOURNAL   Nat Genet 46 (1), 56-60 (2014)
   PUBMED   24292274
REFERENCE   5  (bases 1 to 2699)
  AUTHORS   Berndt,S.I., Skibola,C.F., Joseph,V., Camp,N.J., Nieters,A.,
            Wang,Z., Cozen,W., Monnereau,A., Wang,S.S., Kelly,R.S., Lan,Q.,
            Teras,L.R., Chatterjee,N., Chung,C.C., Yeager,M.,
            Brooks-Wilson,A.R., Hartge,P., Purdue,M.P., Birmann,B.M.,
            Armstrong,B.K., Cocco,P., Zhang,Y., Severi,G.,
            Zeleniuch-Jacquotte,A., Lawrence,C., Burdette,L., Yuenger,J.,
            Hutchinson,A., Jacobs,K.B., Call,T.G., Shanafelt,T.D., Novak,A.J.,
            Kay,N.E., Liebow,M., Wang,A.H., Smedby,K.E., Adami,H.O., Melbye,M.,
            Glimelius,B., Chang,E.T., Glenn,M., Curtin,K.,
            Cannon-Albright,L.A., Jones,B., Diver,W.R., Link,B.K., Weiner,G.J.,
            Conde,L., Bracci,P.M., Riby,J., Holly,E.A., Smith,M.T.,
            Jackson,R.D., Tinker,L.F., Benavente,Y., Becker,N., Boffetta,P.,
            Brennan,P., Foretova,L., Maynadie,M., McKay,J., Staines,A.,
            Rabe,K.G., Achenbach,S.J., Vachon,C.M., Goldin,L.R., Strom,S.S.,
            Lanasa,M.C., Spector,L.G., Leis,J.F., Cunningham,J.M.,
            Weinberg,J.B., Morrison,V.A., Caporaso,N.E., Norman,A.D.,
            Linet,M.S., De Roos,A.J., Morton,L.M., Severson,R.K., Riboli,E.,
            Vineis,P., Kaaks,R., Trichopoulos,D., Masala,G., Weiderpass,E.,
            Chirlaque,M.D., Vermeulen,R.C., Travis,R.C., Giles,G.G.,
            Albanes,D., Virtamo,J., Weinstein,S., Clavel,J., Zheng,T.,
            Holford,T.R., Offit,K., Zelenetz,A., Klein,R.J., Spinelli,J.J.,
            Bertrand,K.A., Laden,F., Giovannucci,E., Kraft,P., Kricker,A.,
            Turner,J., Vajdic,C.M., Ennas,M.G., Ferri,G.M., Miligi,L.,
            Liang,L., Sampson,J., Crouch,S., Park,J.H., North,K.E., Cox,A.,
            Snowden,J.A., Wright,J., Carracedo,A., Lopez-Otin,C., Bea,S.,
            Salaverria,I., Martin-Garcia,D., Campo,E., Fraumeni,J.F. Jr., de
            Sanjose,S., Hjalgrim,H., Cerhan,J.R., Chanock,S.J., Rothman,N. and
            Slager,S.L.
  TITLE     Genome-wide association study identifies multiple risk loci for
            chronic lymphocytic leukemia
  JOURNAL   Nat Genet 45 (8), 868-876 (2013)
   PUBMED   23770605
REFERENCE   6  (bases 1 to 2699)
  AUTHORS   Okada,Y., Hirota,T., Kamatani,Y., Takahashi,A., Ohmiya,H.,
            Kumasaka,N., Higasa,K., Yamaguchi-Kabata,Y., Hosono,N., Nalls,M.A.,
            Chen,M.H., van Rooij,F.J., Smith,A.V., Tanaka,T., Couper,D.J.,
            Zakai,N.A., Ferrucci,L., Longo,D.L., Hernandez,D.G., Witteman,J.C.,
            Harris,T.B., O'Donnell,C.J., Ganesh,S.K., Matsuda,K., Tsunoda,T.,
            Tanaka,T., Kubo,M., Nakamura,Y., Tamari,M., Yamamoto,K. and
            Kamatani,N.
  TITLE     Identification of nine novel loci associated with white blood cell
            subtypes in a Japanese population
  JOURNAL   PLoS Genet 7 (6), e1002067 (2011)
   PUBMED   21738478
REFERENCE   7  (bases 1 to 2699)
  AUTHORS   Lan,Q., Au,W.Y., Chanock,S., Tse,J., Wong,K.F., Shen,M., Siu,L.P.,
            Yuenger,J., Yeager,M., Hosgood,H.D. 3rd, Purdue,M.P., Liang,R. and
            Rothman,N.
  TITLE     Genetic susceptibility for chronic lymphocytic leukemia among
            Chinese in Hong Kong
  JOURNAL   Eur J Haematol 85 (6), 492-495 (2010)
   PUBMED   20731705
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   8  (bases 1 to 2699)
  AUTHORS   Van Veldhoven,P.P.
  TITLE     Biochemistry and genetics of inherited disorders of peroxisomal
            fatty acid metabolism
  JOURNAL   J Lipid Res 51 (10), 2863-2895 (2010)
   PUBMED   20558530
  REMARK    Review article
REFERENCE   9  (bases 1 to 2699)
  AUTHORS   Slager,S.L., Goldin,L.R., Strom,S.S., Lanasa,M.C., Spector,L.G.,
            Rassenti,L., Leis,J.F., Camp,N.J., Kay,N.E., Vachon,C.M., Glenn,M.,
            Weinberg,J.B., Rabe,K.G., Cunningham,J.M., Achenbach,S.J.,
            Hanson,C.A., Marti,G.E., Call,T.G., Caporaso,N.E. and Cerhan,J.R.
  TITLE     Genetic susceptibility variants for chronic lymphocytic leukemia
  JOURNAL   Cancer Epidemiol Biomarkers Prev 19 (4), 1098-1102 (2010)
   PUBMED   20332261
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   10 (bases 1 to 2699)
  AUTHORS   Di Bernardo,M.C., Crowther-Swanepoel,D., Broderick,P., Webb,E.,
            Sellick,G., Wild,R., Sullivan,K., Vijayakrishnan,J., Wang,Y.,
            Pittman,A.M., Sunter,N.J., Hall,A.G., Dyer,M.J., Matutes,E.,
            Dearden,C., Mainou-Fowler,T., Jackson,G.H., Summerfield,G.,
            Harris,R.J., Pettitt,A.R., Hillmen,P., Allsup,D.J., Bailey,J.R.,
            Pratt,G., Pepper,C., Fegan,C., Allan,J.M., Catovsky,D. and
            Houlston,R.S.
  TITLE     A genome-wide association study identifies six susceptibility loci
            for chronic lymphocytic leukemia
  JOURNAL   Nat Genet 40 (10), 1204-1210 (2008)
   PUBMED   18758461
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC114776.3, AC096591.1, AC023131.8 and AC096670.1.
            
            On Jul 3, 2019 this sequence version replaced NM_001142807.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK300513.1, SRR18074969.1451948.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2144333
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000439055.6/ ENSP00000407761.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-202               AC114776.3         105889-106090
            203-299             AC114776.3         141684-141780
            300-383             AC114776.3         158048-158131
            384-470             AC114776.3         166966-167052
            471-569             AC096591.1         202-300
            570-684             AC096591.1         4736-4850
            685-771             AC096591.1         5140-5226
            772-844             AC096591.1         7778-7850
            845-977             AC096591.1         11389-11521
            978-1012            AC096591.1         47497-47531
            1013-1129           AC096591.1         114915-115031
            1130-1283           AC096591.1         139615-139768
            1284-1393           AC023131.8         12799-12908
            1394-1505           AC023131.8         21584-21695
            1506-1593           AC096670.1         167507-167594       c
            1594-1664           AC096670.1         149933-150003       c
            1665-1766           AC096670.1         106255-106356       c
            1767-2699           AC096670.1         80673-81605         c
FEATURES             Location/Qualifiers
     source          1..2699
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q13"
     gene            1..2699
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /note="acyl-CoA oxidase like"
                     /db_xref="GeneID:55289"
                     /db_xref="HGNC:HGNC:25621"
     exon            1..202
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            203..299
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     CDS             225..1967
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /note="isoform 1 is encoded by transcript variant 1;
                     acyl-coenzyme A oxidase-like protein; acyl-CoA
                     oxidase-like protein"
                     /codon_start=1
                     /product="acyl-coenzyme A oxidase-like protein isoform 1"
                     /protein_id="NP_001136279.1"
                     /db_xref="CCDS:CCDS46389.1"
                     /db_xref="GeneID:55289"
                     /db_xref="HGNC:HGNC:25621"
                     /translation="MRALTVQRVKFAMDLPLLKRAGQDLAEKTKNFVSRSLVIGEVLS
                     MADMATGVKCGIIYWLFGGAIRNLGSPEHVTKWFQPLQEQKYTGMFAMTERGHGSNAR
                     GIQTEATFDLSAQEFVIDTPCENAEKMYIGNAMYGNYAAVFAQLIIDGRSQGPHCFIV
                     PVRDENGSLYPGVTAIDMMYKEGLHGVDNGILIFDKVRIPRENLLDKFGSVAPDGQYH
                     SPIRNKSARFNAMLAALTPSRLAVAFQAMGAMKLGLTIAIRYSHSRRQFGPKTKEEVK
                     IIEHQTQTLRLMPHLATALALTFVSRYAGALLDEDVFQGKELVNSRSLQALVAGLKAY
                     STWENIRCLQDCRECTGGMVVGRELLAQYTKQYEEKPLFGLLQNWAESVGDKLRTSFL
                     AFNMDTVDDLAFLLKAVKFRERVLQRGLVARIYYKVKTKKEDFFHAWNSCLHHVASLS
                     LAHTHRVTLEQFSLAVKSCPDQEDQTLLMKFCLLYGTKLVFQERAWYLEHKYLTPMAS
                     TRIRNQLLDLCDSVKDDARRVISTFNIPHTYLHAPIAGISNPRAAWAFYPAPLQPRPR
                     EEARSRRPKLGAKL"
     exon            300..383
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            384..470
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            471..569
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            570..684
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            685..771
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            772..844
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            845..977
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            978..1012
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1129
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1283
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1393
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            1394..1505
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            1506..1593
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            1594..1664
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            1665..1766
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     exon            1767..2699
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2675..2680
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /note="hexamer: AATAAA"
     regulatory      2679..2684
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /note="hexamer: AAGAAA"
     polyA_site      2694
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
     polyA_site      2699
                     /gene="ACOXL"
                     /gene_synonym="ACOX4"
                     /note="major polyA site"
ORIGIN      
        1 acctgctggg agctggagga ggcgcggagc gaagccggcc ctgccagcca cgcggagaag
       61 cagaggcagg tgagcgcgat gcagccggcg ccgggtctgg ggctcgggga ctcctccctg
      121 caccgctacc tggacggcga cttctggagc ctcaagaacg agctgcgcgg actcctcggc
      181 ggcgcccgct cttccggcaa aggtatgatt taagcttgga tgaaatgaga gctttgacag
      241 ttcagagagt gaagtttgcc atggacctgc ctctgttaaa acgtgcaggt caggatctgg
      301 cagagaaaac aaagaatttt gtcagccgaa gccttgtcat aggagaagtc ctctccatgg
      361 cggacatggc cacaggagtg aagtgcggaa taatttattg gctatttggt ggtgctatca
      421 ggaatctcgg aagccctgaa catgttacta agtggtttca gccactccag gagcagaaat
      481 acactgggat gtttgcaatg accgagaggg gccatgggag caacgcgaga gggatccaga
      541 ccgaagccac ctttgacctc tctgcccagg agtttgtaat tgacacgccg tgtgaaaatg
      601 cggagaagat gtatattgga aatgccatgt acgggaatta tgcagctgtc tttgcccagc
      661 tcatcataga tggaagatct caagggcccc actgtttcat cgttcctgtc cgggatgaaa
      721 acggaagctt gtacccagga gtcacagcta ttgatatgat gtacaaggag ggtctgcatg
      781 gtgtggacaa tgggatatta atatttgaca aggttcggat acccagggag aacctgctgg
      841 ataagtttgg ttccgtggct ccagatggac agtaccattc gcctattagg aacaagagtg
      901 caagattcaa tgccatgctg gcagcactga ccccttcgag attagctgtg gctttccaag
      961 ctatgggtgc catgaagctt gggttgacga tagccattcg ctatagccac agccggaggc
     1021 agtttgggcc caaaaccaag gaagaggtga agatcattga gcaccaaaca cagaccctgc
     1081 ggctgatgcc ccacctggcc acagccttgg ccctgacctt cgtcagcagg tatgctgggg
     1141 ccctcctgga tgaggatgtc ttccagggaa aggagctggt caacagtcgc tcgctgcagg
     1201 ctctggtggc ggggctgaag gcctacagca cctgggagaa catccgctgc ctgcaggact
     1261 gccgcgagtg cactggaggc atggttgtgg ggcgggaact gctggcccaa tacaccaaac
     1321 agtatgaaga aaaaccactc tttggcctgc tccaaaactg ggctgaatct gtgggggaca
     1381 agctgagaac cagtttcctg gcatttaaca tggacacagt tgatgatctc gcctttctgt
     1441 tgaaagcagt gaaatttcgt gaaagggttc ttcagcgggg tttggtggcc agaatttatt
     1501 ataaggtaaa gaccaagaag gaggattttt tccatgcctg gaactcgtgt ctgcaccacg
     1561 tggcttctct gtccctggca cacactcacc gagttacctt agagcagttc tccctagcag
     1621 tgaagagctg tcctgaccaa gaggaccaga ctttgttaat gaagttttgt ctgttgtatg
     1681 gaaccaagct ggtgtttcag gagcgggcct ggtatttaga acataaatac ttgactccca
     1741 tggccagcac gaggatcagg aatcagttgc tggatttgtg cgactcggtg aaggatgatg
     1801 cccggagggt gatctcgacc tttaacattc cacacaccta cctccacgca ccaatcgccg
     1861 gaatctccaa cccgcgggcc gcgtgggctt tctaccctgc accgctgcag ccgcggccac
     1921 gggaagaggc gcgctcccgg cggcccaagc tgggagccaa gctctaacgg gtgtggcggg
     1981 aagtgtggtg gcccgccagc agctgccacg acgctcgctc caccgacgcc cagagctgtg
     2041 gccgaggccg ggggctggca cccgctgggc cgccactctc ggggattttg gtggcaaagc
     2101 ggaggtcccg ccgaggctgg cgaggtgcgc ggctggctgc taggaaagag atccagacgg
     2161 tcgcctggtg cgctggatcc ctgtgccctt tccctgaaac ccagcctggc ctgactgcaa
     2221 cctctcccaa cttcagtgcc ggatccccta gacaatcagg gtgggctccc cgctgcgagc
     2281 gcgccccaca gccgggtgcc gccaaaggtc tcctgctgtt agcggtgact cacattccca
     2341 gtgatttaga aaaactgtgg tgccgagtga aagaaaaaaa aaaaagcaaa cacccttaga
     2401 caaaagaaaa aagctccact ctttccgcga gcgggaaaaa aggtttggtt cagcaagtga
     2461 tgctatttca gtgaatcaga cgctctgggg ctctgcaagg aaacgcacgg actgggagaa
     2521 ggaagtggga gcctagagtt ttgctctcgg caaaacaaga actcggcttg tcctcccagg
     2581 ccggcggttt ccgtacggca agacaaggcg cggaaaacat ttttaccatc tgacgctgta
     2641 gtctgtcctt tagaagagaa taggtgaaaa gtttaataaa gaaattaagc gatgtggaa
//
