LOCUS       NM_018473               4041 bp    mRNA    linear   PRI 29-OCT-2024
DEFINITION  Homo sapiens acyl-CoA thioesterase 13 (ACOT13), transcript variant
            1, mRNA.
ACCESSION   NM_018473
VERSION     NM_018473.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4041)
  AUTHORS   Wang,B., Yang,Q., Che,L., Sun,L. and Du,N.
  TITLE     Acyl-CoA thioesterase 13 (ACOT13) attenuates the progression of
            autosomal dominant polycystic kidney disease in vitro via
            triggering mitochondrial-related cell apoptosis
  JOURNAL   Aging (Albany NY) 16 (16), 11877-11892 (2024)
   PUBMED   39172111
  REMARK    GeneRIF: Acyl-CoA thioesterase 13 (ACOT13) attenuates the
            progression of autosomal dominant polycystic kidney disease in
            vitro via triggering mitochondrial-related cell apoptosis.
REFERENCE   2  (bases 1 to 4041)
  AUTHORS   Du,N., Dong,D., Sun,L., Che,L., Li,X., Liu,Y. and Wang,B.
  TITLE     Identification of ACOT13 and PTGER2 as novel candidate genes of
            autosomal dominant polycystic kidney disease through whole exome
            sequencing
  JOURNAL   Eur J Med Res 26 (1), 142 (2021)
   PUBMED   34886911
  REMARK    GeneRIF: Identification of ACOT13 and PTGER2 as novel candidate
            genes of autosomal dominant polycystic kidney disease through whole
            exome sequencing.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4041)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (bases 1 to 4041)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   5  (bases 1 to 4041)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (bases 1 to 4041)
  AUTHORS   Kanno,K., Wu,M.K., Agate,D.S., Fanelli,B.J., Wagle,N., Scapa,E.F.,
            Ukomadu,C. and Cohen,D.E.
  TITLE     Interacting proteins dictate function of the minimal START domain
            phosphatidylcholine transfer protein/StarD2
  JOURNAL   J Biol Chem 282 (42), 30728-30736 (2007)
   PUBMED   17704541
  REMARK    GeneRIF: Yeast two-hybrid screening using libraries prepared from
            mouse liver and embryo identified Them2 (thioesterase superfamily
            member 2) and the homeodomain transcription factor Pax3 (paired box
            gene 3), respectively, as PC-TP-interacting proteins.
REFERENCE   7  (bases 1 to 4041)
  AUTHORS   Cheng,Z., Bao,S., Shan,X., Xu,H. and Gong,W.
  TITLE     Human thioesterase superfamily member 2 (hTHEM2) is co-localized
            with beta-tubulin onto the microtubule
  JOURNAL   Biochem Biophys Res Commun 350 (4), 850-853 (2006)
   PUBMED   17045243
  REMARK    GeneRIF: Small interference RNA silencing in cell line HCT116 shows
            that the hthem2 gene is essential for the cell sustained
            proliferation.
REFERENCE   8  (bases 1 to 4041)
  AUTHORS   Cheng,Z., Song,F., Shan,X., Wei,Z., Wang,Y., Dunaway-Mariano,D. and
            Gong,W.
  TITLE     Crystal structure of human thioesterase superfamily member 2
  JOURNAL   Biochem Biophys Res Commun 349 (1), 172-177 (2006)
   PUBMED   16934754
  REMARK    GeneRIF: analysis of human thioesterase superfamily member 2
            crystal structure
REFERENCE   9  (bases 1 to 4041)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
REFERENCE   10 (bases 1 to 4041)
  AUTHORS   Hu,R.M., Han,Z.G., Song,H.D., Peng,Y.D., Huang,Q.H., Ren,S.X.,
            Gu,Y.J., Huang,C.H., Li,Y.B., Jiang,C.L., Fu,G., Zhang,Q.H.,
            Gu,B.W., Dai,M., Mao,Y.F., Gao,G.F., Rong,R., Ye,M., Zhou,J.,
            Xu,S.H., Gu,J., Shi,J.X., Jin,W.R., Zhang,C.K., Wu,T.M.,
            Huang,G.Y., Chen,Z., Chen,M.D. and Chen,J.L.
  TITLE     Gene expression profiling in the human
            hypothalamus-pituitary-adrenal axis and full-length cDNA cloning
  JOURNAL   Proc Natl Acad Sci U S A 97 (17), 9543-9548 (2000)
   PUBMED   10931946
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DB214267.1, BC000894.1,
            AL031775.1 and CB852340.1.
            
            On Nov 23, 2018 this sequence version replaced NM_018473.3.
            
            Summary: This gene encodes a member of the thioesterase
            superfamily. In humans, the protein co-localizes with microtubules
            and is essential for sustained cell proliferation. The orthologous
            mouse protein forms a homotetramer and is associated with
            mitochondria. The mouse protein functions as a medium- and
            long-chain acyl-CoA thioesterase. Multiple transcript variants
            encoding different isoforms have been found for this gene.[provided
            by RefSeq, May 2009].
            
            Transcript Variant: This variant (1) represents the shorter
            transcript but encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DA893550.1, SRR1803614.16882.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000230048.5/ ENSP00000230048.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-107               DB214267.1         43-149
            108-709             BC000894.1         1-602
            710-3883            AL031775.1         9142-12315          c
            3884-4041           CB852340.1         36-193              c
FEATURES             Location/Qualifiers
     source          1..4041
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p22.3"
     gene            1..4041
                     /gene="ACOT13"
                     /gene_synonym="HT012; PNAS-27; THEM2"
                     /note="acyl-CoA thioesterase 13"
                     /db_xref="GeneID:55856"
                     /db_xref="HGNC:HGNC:20999"
                     /db_xref="MIM:615652"
     exon            1..268
                     /gene="ACOT13"
                     /gene_synonym="HT012; PNAS-27; THEM2"
                     /inference="alignment:Splign:2.1.0"
     CDS             188..610
                     /gene="ACOT13"
                     /gene_synonym="HT012; PNAS-27; THEM2"
                     /EC_number="3.1.2.2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     thioesterase superfamily member 2; hypothalamus protein
                     HT012; acyl-coenzyme A thioesterase 13; palmitoyl-CoA
                     hydrolase; hotdog-fold thioesterase superfamily member 2"
                     /codon_start=1
                     /product="acyl-coenzyme A thioesterase 13 isoform 1"
                     /protein_id="NP_060943.1"
                     /db_xref="CCDS:CCDS4558.1"
                     /db_xref="GeneID:55856"
                     /db_xref="HGNC:HGNC:20999"
                     /db_xref="MIM:615652"
                     /translation="MTSMTQSLREVIKAMTKARNFERVLGKITLVSAAPGKVICEMKV
                     EEEHTNAIGTLHGGLTATLVDNISTMALLCTERGAPGVSVDMNITYMSPAKLGEDIVI
                     TAHVLKQGKTLAFTSVDLTNKATGKLIAQGRHTKHLGN"
     exon            269..453
                     /gene="ACOT13"
                     /gene_synonym="HT012; PNAS-27; THEM2"
                     /inference="alignment:Splign:2.1.0"
     exon            454..4041
                     /gene="ACOT13"
                     /gene_synonym="HT012; PNAS-27; THEM2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      689..694
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ACOT13"
                     /gene_synonym="HT012; PNAS-27; THEM2"
                     /note="hexamer: AATAAA"
     polyA_site      709
                     /gene="ACOT13"
                     /gene_synonym="HT012; PNAS-27; THEM2"
                     /note="major polyA site"
     regulatory      1813..1818
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ACOT13"
                     /gene_synonym="HT012; PNAS-27; THEM2"
                     /note="hexamer: AATAAA"
     polyA_site      1835
                     /gene="ACOT13"
                     /gene_synonym="HT012; PNAS-27; THEM2"
     regulatory      3327..3332
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ACOT13"
                     /gene_synonym="HT012; PNAS-27; THEM2"
                     /note="hexamer: AATAAA"
     polyA_site      3355
                     /gene="ACOT13"
                     /gene_synonym="HT012; PNAS-27; THEM2"
     regulatory      4020..4025
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ACOT13"
                     /gene_synonym="HT012; PNAS-27; THEM2"
                     /note="hexamer: AATAAA"
     polyA_site      4041
                     /gene="ACOT13"
                     /gene_synonym="HT012; PNAS-27; THEM2"
ORIGIN      
        1 agtgagcaaa tcgcggacca ccggggctgc cagctcgcct gactcccggc ctcttgcgct
       61 cctaggggcg gagaagggtg cgggctcttc gccctttgtg tcctccttct ttcactaact
      121 tctggacttt ccagctcttc cgaagttcgt tcttgcgcaa agcccaaagg ctggaaaacc
      181 gtccacgatg accagcatga ctcagtctct gcgggaggtg ataaaggcca tgaccaaggc
      241 tcgcaatttt gagagagttt tgggaaagat tactcttgtc tctgctgctc ctgggaaagt
      301 gatttgtgaa atgaaagtag aagaagagca taccaatgca ataggcactc tccacggcgg
      361 tttgacagcc acgttagtag ataacatatc aacaatggct ctgctatgca cggaaagggg
      421 agcacccgga gtcagtgtcg atatgaacat aacgtacatg tcacctgcaa aattaggaga
      481 agatatagtg attacagcac atgttctgaa gcaaggaaaa acacttgcat ttacctctgt
      541 ggatctgacc aacaaggcca caggaaaatt aatagcacaa ggaagacaca caaaacacct
      601 gggaaactga gagaacagca gaatgaccta aagaaaccca acaatgaata tcaagtatag
      661 atttgactca aacaattgta atttttgaaa taaactagca aaaccagaag cagctagaaa
      721 tattcttgga ggaaaaggac ctggatatca agtagggtaa aggtgggggt gtcttttttc
      781 actttaagca tcttgttttc taatcatgtg tgataattgg gtgaaaaatt cttagctcaa
      841 agtgttttaa aaacaggtaa agcaaagaaa ctagcaggac cactctcagt taagattaaa
      901 actaaagtcc agtgttaagc taaaggagaa atagaaatta atggttctaa ttctgtttgg
      961 gctgctagga acaacagaaa tttttcatgg ttctagaagc tggaaagtcc tgggtcaagg
     1021 cccagcagat cctgttaggt gagggcccgc ttcctggctc atagatggtg ccttctcact
     1081 gtgtggtgga aggggcaagt gagccctctg ggttctcgtt tttgaaatgg agtctcgctc
     1141 tgttgcccag gctggagtac agcagcacga tctcggctca ctgcaatctc tgccccctgg
     1201 gttcaagtga ttctcctgcc tcagcctccc aagtagctgg gactataggc atgtgccatc
     1261 acacctagct aatttttgta gttttttgta gaaacagggt tcaccatgtt ggccaggctg
     1321 gtctcgaact cgtgacctca ggtgatccgc ctgccttggc cccccaaagt gctgggatta
     1381 caggtgtgag ccaatgtgcc cagcctgggt tctcttttgt aagggcactt actccaatct
     1441 tgagggttct gccctcgtga tctaataact tcccaaagac ccccacctgc taatatcacc
     1501 ttgggggttg ggattttaac atacaaattt aggggaaaca catggagacc acagcaatgg
     1561 ccaatcctta gcgaatctta ggtccttccc agatctaaaa tgccaagcta cacttgcatt
     1621 tccttttttt aagattatga aacttcaaaa tatatgaact acagcccata ttgaaaaata
     1681 aaatagattg agccatatgc ctaaaaaaga cctcaagaaa agtttgaggc taagcatgtt
     1741 agtgttacag gaaatggtcc aatagagggg gaagaaaaaa agcatgctac tagccccttt
     1801 tcttgtaccg agaataaaac catgcagatc tcaaacctcc aagtctatag tattgaaaag
     1861 accaagttca cttctcagaa gtctccaagt tcagttgact gtggcactct gagacagctt
     1921 ctgtcactca ggctggagtg atacaatcac agcttcccat agcctcaaaa tcccaggctc
     1981 aagacattct tccacctcag tctcctgagt agctggaact acaggcgtgt gccaccacgc
     2041 ctaattttat ttttgtagaa acaaggtctc actgttgccc agcctcgtct caaactccta
     2101 ggctcaagca atcctcctgc cttggccccc caagtactgg acttacaggt gtgaaccact
     2161 gcacccagct gactcttact tgatttctgt cagggaatct taatgaacat ttcatgacta
     2221 aagactaaaa aggatgcagc tttaagtaaa tttaagtcaa gttaacagtt aaagacaaat
     2281 cctttcccta cattagatcg cctgctgatc tgtccactgt gaaagggcag aagactccac
     2341 agtagcaata gcagcagtga gcatacagga gtcccagatg tttacttcta gtatttccca
     2401 ctaaaaggaa gctgggctcc ttggagaaac agctgactcc agggcttgag gctgggacag
     2461 aaaggttaca gtatcttatg catgaaagga gatgctcaaa ataataaagg catgcaaatt
     2521 atgatttgga gggaaaaaat atgaggccat agtgtttagg tagataataa atggcagaga
     2581 tagaacactc tcttacaaca aatgctgtaa atggacaaag cattagattt ggaaaatcac
     2641 tattttgtaa ccatcatagt taaagactgg tttgggtttt agtctggaaa gaatcgccaa
     2701 gggagctcct gataaaggaa cagggtattt gcacattgct tcccagagat tgctagtagt
     2761 aagtaccaca catagggcaa aaccaggaca ccttgaccag gcgctcaaaa gtaacatcaa
     2821 tgaagagcag atggagagta tacttgagaa gggcgttaag catgaataaa caattcaaat
     2881 gcaaaatgag taacaattta caagaaaaat tgccctgtac tccaaaaaac atagaggtca
     2941 tggaacacat aaaggctaag gaactgttcc acattaaaga caactgagaa caactaaatt
     3001 caatgatcct gtactctaga gggggggatc taaaacaagc taccaaggat actgggacaa
     3061 caaaacgaat atggatgata aagagtatca acattccctg agtttggtaa ttttactcta
     3121 gttatatgaa atattcttgt acttggaaca tatgccgaag tactaaggaa ggggtaagga
     3181 agcacaaagt gtgcaacaaa ctcaaatagc tcacaggtat aagtgtacag agaaaatgaa
     3241 aaaaatgtgg caaaataata aaaatgaggg taaagattac acaacagctt tcatattact
     3301 ctggtaactt ttctaaatta ttccaaaata aaaacgtaaa caatggctgc caaaatgcct
     3361 aacttggtga acataagtgt aattcaatat ggtaaattaa ttcaacatgg taaattaaga
     3421 gcataggcct taagagccag ccagcctggt tttaaatcct ccactactta tgatctgagc
     3481 ttgagcaagt tacttaacct ctgcatctat ttccaccaaa ggttgagagg ttaagacaag
     3541 agcttagaag agtacctggt tataataaac attcaaaatg ttatttcaaa tagattctaa
     3601 tttttaaata agaggacaca tgaaagcatt ttgaaattta agaatggccc tttcccatga
     3661 agcaaggcat aaggccaggt tgctaactgt tgaaagctga cagtatgttc ttgattcctg
     3721 ttcttgttga agttacacac tcaattgcca ggtatttttc ttctgaattt actatttagc
     3781 cacagactat gaaataattc tctaaggtga ccagtaacat cagtgaaatg gaaagaaaaa
     3841 gttaacactt caaactttgt gtattcacct gaatagtcag ggaactttca cctattttat
     3901 ttaggttttc tttttctttt tttctttttt tttcaaattc caaccagaag ctaaatacaa
     3961 ttggaaactg gtaagcacta gttttactcc aaaggagtag gatcattcag atttactcca
     4021 ataaaagtat gcaaccctta a
//
