LOCUS       NM_001031854            1820 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens 1-aminocyclopropane-1-carboxylate synthase homolog
            (inactive) like (ACCSL), transcript variant 1, mRNA.
ACCESSION   NM_001031854 XM_372375
VERSION     NM_001031854.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1820)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 1820)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC134775.8, AB231734.1, AB231732.1, AB231733.1 and DW009984.1.
            
            On Jun 28, 2007 this sequence version replaced NM_001031854.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB231734.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1968968 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000378832.1/ ENSP00000368109.1
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-44                AC134775.8         70653-70696         c
            45-631              AB231734.1         45-631
            632-984             AB231732.1         211-563
            985-1334            AB231733.1         292-641
            1335-1346           AB231732.1         914-925
            1347-1646           DW009984.1         46-345
            1647-1820           AB231734.1         1647-1820
FEATURES             Location/Qualifiers
     source          1..1820
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p11.2"
     gene            1..1820
                     /gene="ACCSL"
                     /note="1-aminocyclopropane-1-carboxylate synthase homolog
                     (inactive) like"
                     /db_xref="GeneID:390110"
                     /db_xref="HGNC:HGNC:34391"
     exon            1..560
                     /gene="ACCSL"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..1763
                     /gene="ACCSL"
                     /note="isoform 1 is encoded by transcript variant 1;
                     1-aminocyclopropane-1-carboxylate synthase-like protein 2;
                     ACC synthase-like protein 2;
                     1-aminocyclopropane-1-carboxylate synthase
                     (inactive)-like; probable inactive
                     1-aminocyclopropane-1-carboxylate synthase-like protein 2;
                     1-aminocyclopropane-1-carboxylate synthase
                     homolog(non-functional)-like"
                     /codon_start=1
                     /product="probable inactive
                     1-aminocyclopropane-1-carboxylate synthase-like protein 2
                     isoform 1"
                     /protein_id="NP_001027025.2"
                     /db_xref="CCDS:CCDS41636.1"
                     /db_xref="GeneID:390110"
                     /db_xref="HGNC:HGNC:34391"
                     /translation="MSHRSDTLPVPSGQRRGRVPRDHSIYTQLLEITLHLQQAMTEHF
                     VQLTSRQGLSLEERRHTEAICEHEALLSRLICRMINLLQSGAASGLELQVPLPSEDSR
                     GDVRYGQRAQLSGQPDPVPQLSDCEAAFVNRDLSIRGIDISVFYQSSFQDYNAYQKDK
                     YHKDKNTLGFINLGTSENKLCMDLMTERLQESDMNCIEDTLLQYPDWRGQPFLREEVA
                     RFLTYYCRAPTRLDPENVVVLNGCCSVFCALAMVLCDPGEAFLVPAPFYGGFAFSSRL
                     YAKVELIPVHLESEVTVTNTHPFQLTVDKLEEALLEARLEGKKVRGLVLINPQNPLGD
                     IYSPDSLMKYLEFAKRYNLHVIIDEIYMLSVFDESITFHSILSMKSLPDSNRTHVIWG
                     TSKDFGISGFRFGALYTHNKEVASAVSAFGYLHSISGITQHKLCQLLQNTEWIDKVYL
                     PTNCYRLREAHKYITAELKALEIPFHNRSSGLYVWINLKKYLDPCTFEEERLLYCRFL
                     DNKLLLSRGKTYMCKEPGWFCLIFADELPRLKLAMRRFCDVLQEQKEALIVKQLEDAM
                     RE"
     exon            561..620
                     /gene="ACCSL"
                     /inference="alignment:Splign:2.1.0"
     exon            621..691
                     /gene="ACCSL"
                     /inference="alignment:Splign:2.1.0"
     exon            692..761
                     /gene="ACCSL"
                     /inference="alignment:Splign:2.1.0"
     exon            762..828
                     /gene="ACCSL"
                     /inference="alignment:Splign:2.1.0"
     exon            829..926
                     /gene="ACCSL"
                     /inference="alignment:Splign:2.1.0"
     exon            927..1004
                     /gene="ACCSL"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1105
                     /gene="ACCSL"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1195
                     /gene="ACCSL"
                     /inference="alignment:Splign:2.1.0"
     exon            1196..1241
                     /gene="ACCSL"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1383
                     /gene="ACCSL"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1526
                     /gene="ACCSL"
                     /inference="alignment:Splign:2.1.0"
     exon            1527..1680
                     /gene="ACCSL"
                     /inference="alignment:Splign:2.1.0"
     exon            1681..1820
                     /gene="ACCSL"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctctttctc cataggtgcc aggcagcctt cagaggccag taaagatacc cggagtatga
       61 gtcatcggtc agacaccctt cctgtgccct ctggtcagag gagaggccgg gtccccagag
      121 accacagcat ctatacccag ctgttggaga taacgctgca cttgcagcag gccatgacgg
      181 agcacttcgt gcagctgacg agcagacagg gcctgtcgct ggaggaaagg aggcacactg
      241 aggccatctg tgagcatgaa gcccttctga gtcgcttaat atgccggatg atcaacctcc
      301 tacagtctgg ggccgcgagt ggcctggagc tccaagtgcc tcttccttct gaggactcta
      361 ggggtgatgt cagatatggg cagagggccc aactctctgg gcagcctgat ccagttcccc
      421 aactgagtga ttgtgaagct gcctttgtca accgcgacct atccatccgt gggattgaca
      481 tctctgtctt ttatcagtcg agcttccagg actacaatgc ctaccaaaaa gataaatatc
      541 ataaggacaa gaacaccttg ggtttcatta accttggcac cagtgagaac aagctctgca
      601 tggatctgat gactgaaaga ttgcaagaaa gtgacatgaa ctgcattgag gacaccttgc
      661 ttcagtaccc tgattggaga gggcagccat tcctgcggga agaagtggcc cggttcctga
      721 cctactactg cagggcacct acccgacttg acccagaaaa tgtggtggtt ctaaatggct
      781 gctgctctgt cttctgtgcc ctggccatgg ttctgtgtga tccaggcgag gccttcctgg
      841 tccctgctcc cttctatggt ggctttgcct ttagctcccg cctgtatgca aaggttgagt
      901 tgattcctgt ccacctggag agtgaggtca ctgttacaaa cacccatcct ttccagctca
      961 ctgtggacaa gttagaggaa gccctgcttg aagctaggct tgaggggaaa aaggtccgag
     1021 gccttgtgct aatcaaccct cagaatcctc tgggtgacat ctactcccca gactcactga
     1081 tgaaatacct ggaatttgcc aagaggtata acctacatgt gatcatagat gagatttaca
     1141 tgctgtctgt gtttgatgaa tccatcacat tccacagcat tctgagcatg aaaagtttgc
     1201 ctgatagcaa caggacccat gtgatctggg gtaccagtaa ggattttggc atctctggct
     1261 tccgctttgg tgctctgtat acccacaaca aggaggtggc ctctgctgtg agtgcctttg
     1321 gctacctcca cagtatttct ggcatcaccc agcacaagct gtgtcaactg ctccagaaca
     1381 cagaatggat tgacaaagta tacctaccca ccaattgcta ccggctccgg gaagctcaca
     1441 agtacatcac tgctgagctg aaggcattgg agatcccttt tcacaaccgc agctctggcc
     1501 tctatgtctg gatcaacttg aaaaagtacc tggatccctg tacatttgaa gaagaacggc
     1561 tcctctattg ccgcttcctg gacaacaagc tattgttatc ccgtggcaaa acctacatgt
     1621 gtaaggagcc aggctggttc tgcctcatct ttgcagatga gctcccccgg ctaaaattgg
     1681 ctatgcgtcg gttctgtgat gtgctgcagg agcagaagga ggctttgata gtgaagcagt
     1741 tggaggatgc aatgagggag taggccgtct gcctcccaac cagcagttcc agcccatcac
     1801 ttgctcaggg accccctaat
//
