LOCUS       NM_015407               1066 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens abhydrolase domain containing 14A (ABHD14A), mRNA.
ACCESSION   NM_015407
VERSION     NM_015407.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1066)
  AUTHORS   Hoshino,J., Aruga,J., Ishiguro,A. and Mikoshiba,K.
  TITLE     Dorz1, a novel gene expressed in differentiating cerebellar granule
            neurons, is down-regulated in Zic1-deficient mouse
  JOURNAL   Brain Res Mol Brain Res 120 (1), 57-64 (2003)
   PUBMED   14667578
  REMARK    GeneRIF: Identification and characterization of Mouse Dorz1, along
            with sequence comparison to a similar protein in human.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CN256406.1, BC002571.2 and AY358201.1.
            
            On Nov 22, 2018 this sequence version replaced NM_015407.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC002571.2, SRR1660803.63732.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000273596.8/ ENSP00000273596.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 CN256406.1         43-46
            5-166               BC002571.2         1-162
            167-167             AY358201.1         162-162
            168-1066            BC002571.2         164-1062
FEATURES             Location/Qualifiers
     source          1..1066
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p21.2"
     gene            1..1066
                     /gene="ABHD14A"
                     /gene_synonym="DORZ1"
                     /note="abhydrolase domain containing 14A"
                     /db_xref="GeneID:25864"
                     /db_xref="HGNC:HGNC:24538"
                     /db_xref="MIM:618771"
     exon            1..141
                     /gene="ABHD14A"
                     /gene_synonym="DORZ1"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..888
                     /gene="ABHD14A"
                     /gene_synonym="DORZ1"
                     /note="abhydrolase domain-containing protein 14A;
                     alpha/beta hydrolase domain-containing protein 14A"
                     /codon_start=1
                     /product="protein ABHD14A"
                     /protein_id="NP_056222.2"
                     /db_xref="CCDS:CCDS2843.1"
                     /db_xref="GeneID:25864"
                     /db_xref="HGNC:HGNC:24538"
                     /db_xref="MIM:618771"
                     /translation="MVGALCGCWFRLGGARPLIPLGPTVVQTSMSRSQVALLGLSLLL
                     MLLLYVGLPGPPEQTSCLWGDPNVTVLAGLTPGNSPIFYREVLPLNQAHRVEVVLLHG
                     KAFNSHTWEQLGTLQLLSQRGYRAVALDLPGFGNSAPSKEASTEAGRAALLERALRDL
                     EVQNAVLVSPSLSGHYALPFLMRGHHQLHGFVPIAPTSTQNYTQEQFWAVKTPTLILY
                     GELDHILARESLRQLRHLPNHSVVKLRNAGHACYLHKPQDFHLVLLAFLDHLP"
     exon            142..353
                     /gene="ABHD14A"
                     /gene_synonym="DORZ1"
                     /inference="alignment:Splign:2.1.0"
     exon            354..469
                     /gene="ABHD14A"
                     /gene_synonym="DORZ1"
                     /inference="alignment:Splign:2.1.0"
     exon            470..705
                     /gene="ABHD14A"
                     /gene_synonym="DORZ1"
                     /inference="alignment:Splign:2.1.0"
     exon            706..1066
                     /gene="ABHD14A"
                     /gene_synonym="DORZ1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1036..1041
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ABHD14A"
                     /gene_synonym="DORZ1"
                     /note="hexamer: AATAAA"
     polyA_site      1066
                     /gene="ABHD14A"
                     /gene_synonym="DORZ1"
                     /note="major polyA site"
ORIGIN      
        1 gcaggcgcgc cgagatggcc gcgctcctgg ccgcctagag ccggagcggc ccgcggagct
       61 gcggaggcag ccatggtcgg ggcgctgtgc ggctgctggt tccgcctggg cggggcccgc
      121 ccgctcatcc cgttgggccc gactgtggta cagacctcca tgagccggtc ccaggtagcc
      181 ctgctgggcc tgagtctgct gctcatgctc ctactgtatg tggggctgcc aggcccccct
      241 gagcagactt cctgcctctg gggagacccc aatgtcacag tcctggctgg tctcacccct
      301 ggcaactcgc ccatctttta ccgcgaggtg ctcccactca accaggcaca cagggtggag
      361 gtggtgctgc ttcatggaaa ggcctttaac tctcacacgt gggagcagct gggcacactg
      421 cagctactgt cacagagggg ctaccgggcc gtggcccttg accttccagg ttttgggaac
      481 tcggcacctt caaaggaggc aagcacagag gcagggcggg cagcgctgct ggagcgggcg
      541 ctgcgggacc tggaggtaca gaatgccgtg ttggtgagcc cctcgctgag tggccactat
      601 gccctgccct tcctgatgcg aggccaccac cagctacatg gatttgtgcc catcgcaccc
      661 acctccaccc agaactacac ccaggagcaa ttctgggctg tgaagactcc aacccttatc
      721 ctgtatggag agctggacca catcctggct cgagagtcac tgcggcagct ccgccacctg
      781 cccaaccact ctgtggtgaa gctacgcaat gcaggccatg cctgttacct ccacaagccg
      841 caagacttcc accttgtcct gcttgccttc cttgaccatc taccttgaac taacccactc
      901 ccagctccca gcctggcatg agcttggaca gtctggaccg ccaccctccc tgaaccaggg
      961 agacagcctc tgggattgga ggccagaggc cagggtcaga cccagccagg actcctcatt
     1021 tcatctcaca gacacaataa aaaagcatat ttgtcctgcc tgggaa
//
