LOCUS       NM_032859               5313 bp    mRNA    linear   PRI 17-DEC-2024
DEFINITION  Homo sapiens abhydrolase domain containing 13 (ABHD13), mRNA.
ACCESSION   NM_032859
VERSION     NM_032859.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5313)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   2  (bases 1 to 5313)
  AUTHORS   Hosgood,H.D. 3rd, Zhang,L., Shen,M., Berndt,S.I., Vermeulen,R.,
            Li,G., Yin,S., Yeager,M., Yuenger,J., Rothman,N., Chanock,S.,
            Smith,M. and Lan,Q.
  TITLE     Association between genetic variants in VEGF, ERCC3 and
            occupational benzene haematotoxicity
  JOURNAL   Occup Environ Med 66 (12), 848-853 (2009)
   PUBMED   19773279
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   3  (bases 1 to 5313)
  AUTHORS   Anney,R.J., Lasky-Su,J., O'Dushlaine,C., Kenny,E., Neale,B.M.,
            Mulligan,A., Franke,B., Zhou,K., Chen,W., Christiansen,H.,
            Arias-Vasquez,A., Banaschewski,T., Buitelaar,J., Ebstein,R.,
            Miranda,A., Mulas,F., Oades,R.D., Roeyers,H., Rothenberger,A.,
            Sergeant,J., Sonuga-Barke,E., Steinhausen,H., Asherson,P.,
            Faraone,S.V. and Gill,M.
  TITLE     Conduct disorder and ADHD: evaluation of conduct problems as a
            categorical and quantitative trait in the international multicentre
            ADHD genetics study
  JOURNAL   Am J Med Genet B Neuropsychiatr Genet 147B (8), 1369-1378 (2008)
   PUBMED   18951430
REFERENCE   4  (bases 1 to 5313)
  AUTHORS   Dunham,A., Matthews,L.H., Burton,J., Ashurst,J.L., Howe,K.L.,
            Ashcroft,K.J., Beare,D.M., Burford,D.C., Hunt,S.E.,
            Griffiths-Jones,S., Jones,M.C., Keenan,S.J., Oliver,K., Scott,C.E.,
            Ainscough,R., Almeida,J.P., Ambrose,K.D., Andrews,D.T.,
            Ashwell,R.I., Babbage,A.K., Bagguley,C.L., Bailey,J., Bannerjee,R.,
            Barlow,K.F., Bates,K., Beasley,H., Bird,C.P., Bray-Allen,S.,
            Brown,A.J., Brown,J.Y., Burrill,W., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M.E., Clark,S.Y., Clarke,G., Clee,C.M.,
            Clegg,S.C., Cobley,V., Collins,J.E., Corby,N., Coville,G.J.,
            Deloukas,P., Dhami,P., Dunham,I., Dunn,M., Earthrowl,M.E.,
            Ellington,A.G., Faulkner,L., Frankish,A.G., Frankland,J.,
            French,L., Garner,P., Garnett,J., Gilbert,J.G., Gilson,C.J.,
            Ghori,J., Grafham,D.V., Gribble,S.M., Griffiths,C., Hall,R.E.,
            Hammond,S., Harley,J.L., Hart,E.A., Heath,P.D., Howden,P.J.,
            Huckle,E.J., Hunt,P.J., Hunt,A.R., Johnson,C., Johnson,D., Kay,M.,
            Kimberley,A.M., King,A., Laird,G.K., Langford,C.J., Lawlor,S.,
            Leongamornlert,D.A., Lloyd,D.M., Lloyd,C., Loveland,J.E.,
            Lovell,J., Martin,S., Mashreghi-Mohammadi,M., McLaren,S.J.,
            McMurray,A., Milne,S., Moore,M.J., Nickerson,T., Palmer,S.A.,
            Pearce,A.V., Peck,A.I., Pelan,S., Phillimore,B., Porter,K.M.,
            Rice,C.M., Searle,S., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
            Smith,M., Steward,C.A., Sycamore,N., Tester,J., Thomas,D.W.,
            Tracey,A., Tromans,A., Tubby,B., Wall,M., Wallis,J.M., West,A.P.,
            Whitehead,S.L., Willey,D.L., Wilming,L., Wray,P.W., Wright,M.W.,
            Young,L., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E., Beck,S.,
            Bentley,D.R., Rogers,J. and Ross,M.T.
  TITLE     The DNA sequence and analysis of human chromosome 13
  JOURNAL   Nature 428 (6982), 522-528 (2004)
   PUBMED   15057823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL157762.13, BQ424339.1, BC022566.1, BX647428.1 and BC018608.1.
            
            On Nov 23, 2018 this sequence version replaced NM_032859.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803616.229993.1,
                                           SRR1660803.248558.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000375898.4/ ENSP00000365063.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                AL157762.13        16450-16472
            24-110              BQ424339.1         1-87
            111-1982            BC022566.1         4-1875
            1983-3879           BX647428.1         1540-3436
            3880-5313           BC018608.1         873-2306
FEATURES             Location/Qualifiers
     source          1..5313
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q33.3"
     gene            1..5313
                     /gene="ABHD13"
                     /gene_synonym="bA153I24.2; BEM46L1; C13orf6"
                     /note="abhydrolase domain containing 13"
                     /db_xref="GeneID:84945"
                     /db_xref="HGNC:HGNC:20293"
                     /db_xref="MIM:621039"
     exon            1..268
                     /gene="ABHD13"
                     /gene_synonym="bA153I24.2; BEM46L1; C13orf6"
                     /inference="alignment:Splign:2.1.0"
     exon            269..5313
                     /gene="ABHD13"
                     /gene_synonym="bA153I24.2; BEM46L1; C13orf6"
                     /inference="alignment:Splign:2.1.0"
     CDS             289..1302
                     /gene="ABHD13"
                     /gene_synonym="bA153I24.2; BEM46L1; C13orf6"
                     /note="abhydrolase domain-containing protein 13;
                     alpha/beta hydrolase domain-containing protein 13"
                     /codon_start=1
                     /product="protein ABHD13"
                     /protein_id="NP_116248.2"
                     /db_xref="CCDS:CCDS32007.1"
                     /db_xref="GeneID:84945"
                     /db_xref="HGNC:HGNC:20293"
                     /db_xref="MIM:621039"
                     /translation="MEKSWMLWNFVERWLIALASWSWALCRISLLPLIVTFHLYGGII
                     LLLLIFISIAGILYKFQDVLLYFPEQPSSSRLYVPMPTGIPHENIFIRTKDGIRLNLI
                     LIRYTGDNSPYSPTIIYFHGNAGNIGHRLPNALLMLVNLKVNLLLVDYRGYGKSEGEA
                     SEEGLYLDSEAVLDYVMTRPDLDKTKIFLFGRSLGGAVAIHLASENSHRISAIMVENT
                     FLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCRMPSLFISGLSDQLIPPVMM
                     KQLYELSPSRTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVVKSHSPEEMAKTSSNV
                     TII"
     regulatory      1957..1962
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ABHD13"
                     /gene_synonym="bA153I24.2; BEM46L1; C13orf6"
                     /note="hexamer: AATAAA"
     polyA_site      1980
                     /gene="ABHD13"
                     /gene_synonym="bA153I24.2; BEM46L1; C13orf6"
                     /note="major polyA site"
     regulatory      3036..3041
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ABHD13"
                     /gene_synonym="bA153I24.2; BEM46L1; C13orf6"
                     /note="hexamer: ATTAAA"
     polyA_site      3058
                     /gene="ABHD13"
                     /gene_synonym="bA153I24.2; BEM46L1; C13orf6"
     regulatory      5288..5293
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ABHD13"
                     /gene_synonym="bA153I24.2; BEM46L1; C13orf6"
                     /note="hexamer: AATAAA"
     polyA_site      5313
                     /gene="ABHD13"
                     /gene_synonym="bA153I24.2; BEM46L1; C13orf6"
ORIGIN      
        1 agagcgggca gggttcccac tccgggagcg gagacggaga acaggttatg tgggagccgg
       61 cgggggcatt tgccggcgac acccgagcgg gggccggaag tggggccaca gctcgcagca
      121 ggagctccgg gctagaccgt ggcgccggca gcggcccctg ggctggagga ggatgatgag
      181 gagcgacgga agcgacgcgg gggtacgctg ctgcgcggcg cccggtttcg tgcccgcggc
      241 cgactgcgca gcctgtccgc gagtctgaga tacttacaga gagctacaat ggaaaagtcc
      301 tggatgctgt ggaactttgt tgaaagatgg ctaatagcct tggcttcatg gtcttgggct
      361 ctctgccgta tttctctttt acctttaata gtgacttttc atctgtatgg aggcattatc
      421 ttacttttgt taatattcat atcaatagca ggtattctgt ataaattcca ggatgtattg
      481 ctttattttc cagaacagcc atcctcttca cgtctttatg ttcccatgcc cactggcatt
      541 ccacatgaaa acattttcat cagaaccaaa gatggaatac gtctgaatct tattttgata
      601 cgatacactg gagacaattc accctattcc ccaactataa tttattttca tgggaatgca
      661 ggcaacatag gtcacaggtt gccaaatgca ttacttatgt tggttaacct caaagttaac
      721 cttttgctgg ttgattatcg aggatatgga aaaagtgaag gagaagcaag tgaagaagga
      781 ctctacttag attctgaagc tgtgttagac tacgtgatga ctagacctga ccttgataaa
      841 acaaaaattt ttctttttgg ccgttccttg ggtggagcag tggctattca tttggcttct
      901 gaaaattcac ataggatttc agccattatg gtggagaaca catttttaag cataccacat
      961 atggccagca ctttattttc attctttccg atgcgttacc ttcctttatg gtgctacaaa
     1021 aataaatttt tgtcctacag aaaaatctct cagtgtagaa tgccttcact tttcatctct
     1081 ggactctcag atcaattaat tccaccagta atgatgaaac aactttatga actctcccca
     1141 tctcggacta agagattagc catttttcca gatgggactc acaatgacac atggcagtgc
     1201 caaggctatt tcactgcact tgaacagttc atcaaagaag tcgtaaagag ccattctcct
     1261 gaagaaatgg caaaaacttc atctaatgta acaattatat aatgtttccc tttttgatta
     1321 ttgcattgta ttttaatttg tgcagaatga taaagaatgt tccttttaga agtgtgttat
     1381 gtctgtacct gtctgaagag tgacattaaa ctttgaaagg acttcactgc tcctttacga
     1441 tattccaaat agttttttac attggaaaaa ctaattcttg ggattctttc atacattttc
     1501 atcaaaactt tcagtgtgat tatgtattca tatcttcagt ttaatatgtc agtataatag
     1561 atattgttca aaagtttctt gttgctaaag tggtgtaatc tgttacacag atgaatagct
     1621 agatgtggaa agagatatgt aaacaagaaa cctttgggta ttgtttctta agtaaatatt
     1681 gggacaatca tggtaagcaa acttagttct gtaactgcat ttttcacctt aaaagttaaa
     1741 tgaaatgcat gatggtattt tattccttga attatgcaat gcaacatttt acatgtaaat
     1801 agcactggtc atatactgat gtatatggtt atctgggtta tatctatttt tatgtaaact
     1861 ctattttgtt tttggcaaga agtgaaattg agacttatgt gcaggttgcc attgaatttt
     1921 gctctggtga atgctgagat ccagcttttt cttacaaata aatgggaccc tgttttccaa
     1981 tacaaatgta ccgtgttttt gttaggtaca gtctggatca tggcatgtag aaatagaaat
     2041 ttagaatttt actgcagctt tgatgtgcat atttgaactt tttaacattt gtaactttgg
     2101 tggcaaagag aattttagct tctatcgatt ttgtaagtct tcagctgaac cactaatagc
     2161 agtcatagtg aagattagca ctacttagaa ttaaattagg aagtctttta tcattgcagg
     2221 attgtacata ctactttata aaaattctca cctttgattt taaatcccag tacctagtta
     2281 tatctaacct atcaaaggca agatatcatt tattggactt cttgaaaata aaagttacaa
     2341 aatccaacaa caacaacaac aaaacaatgt tcttggtttt aatgttccag ttgctgtgaa
     2401 atagaactcc tacaatcaaa agacagtttt aggaagtctt atttattgat tttaaaagtt
     2461 ttacatgtag gagtgtggga atgaaggaat tctggagctt tttgacacaa aacctattac
     2521 cacatttagc agttaaatgg ctataggtgg gaagtaggat ttagatgtat agaaaagtaa
     2581 gaaaatctta cttagaaaaa agccccttga aacttgcagg atttacttaa taaaaataca
     2641 cgctatgagt cataattgtg ccaagttgtt tcatgcagtc ctcaaaaatt agatgtaatt
     2701 gagctttgtg taatattatg tcagctttaa catataatat tttgaatatt ttagctatat
     2761 ttagtggctt tctgcaagca actagaacag agaagtaatg ggtcaataat cttgacctta
     2821 atttaaaact ttcaatggag atagggctag aaatactttt gccaaatagc attcttattc
     2881 actttatgcc ggtatttaga aaaaataaat tatagcaagt atgatttcta agaatgtttt
     2941 tctataaatt actaattgta aaaagtcttg ctttttaaaa caagttggta atgcatatca
     3001 tggaaggcat attttgtatg tataaattca ccacaattaa agattattct tgtcagtcct
     3061 tgctatgtag aatgactatt ctaaatatta atgtattaaa aagaaaatac aacaaaatgt
     3121 atatttagac acgagcttac atggcatacc ttatatttgt atcattcttt aaagtttaca
     3181 aaaaaaaacc ttatgttttt atgtaatcag tcattacact agggagaaat ttatcagctt
     3241 tagttctaaa tatgctcatg aggtataaaa gctatttctt catcagtatt ttgcttttat
     3301 gctgcttttt ctttttgata ctccaggttt ataaactatc ttttaaaatt ttaagccagg
     3361 acttcaaaaa ttgtagagta cttgtttggc gttccctacc ttcattctct tagggttaag
     3421 gagcctttct ttctgcagct aagggcagag gctgtgccta gggctatacc accactagca
     3481 tctgtatttg agactgtttc cttagatggg taagaggtgg aaaacaaact tagtatcagg
     3541 ggtccatgaa gcccatggca tcatttttga aaatatttct agttttgtag ccaaagcaat
     3601 tggttttagt aaaatgagac ttcttcagga gtcactcctt tactgtggac ccattgctta
     3661 gtgggaatgg aagtatatgt atctatcttg tgtattaact tctgacttat ttatacaaga
     3721 gcagctatag gagtttacaa aagaacttta agttattaag ttactataaa tttggggatc
     3781 ctagagtgat cttaaatatg gcaagataca gctcatttag aataaaatct cacatccatt
     3841 attttaaagg gaatgattgg ggggaaaaac tggtgaaaaa gaaatataaa aaggacccta
     3901 aaaagaattc tgcaaaataa gagaagaaat aatttgtgac aggtaataga atactagtag
     3961 gatagaaaca actagaaagg aaagtgtgac acagttttta aatttagatg tagaaaataa
     4021 tgaattaatg agattggtga aaggaaatca tgcaaaacat ttgaatgcaa agcatttcta
     4081 acaaaaagtg actggagcac ttgccattgc aacaaccctg tttttgcaat taggtttttg
     4141 actgttaaaa tggatatttt cataaaaatg gtgttctgaa ttttgctaca gggctgctta
     4201 aatttatgat tacctgtaga cacttgatat ttacatagat tacagctttg gtaatatgtc
     4261 actggagtaa ttacgctgta atacctgttg agaattcata ccatctgatg cttatatatt
     4321 aatttcttat gtttgtaagt ttggctttgt gggaataggt gtggagaaat taaagagtga
     4381 aggccatatt tcatttttta taaattatct ttcaagctca gatagcttaa gagcagttta
     4441 tattaaggag acccttttct ccttgaggat agggataggt aaggtaaact tgtaaaaagg
     4501 atgtcacaga agtcactttt taattaagtc atgattgaga tactgaactc ttccactcat
     4561 tcttctttcc cattttccta ttatgtttga taattatatg tatttttaaa aactgtgaga
     4621 ggaaaaatta gtcataaccc ttttgggtta tccacttaaa tttaggtatt ttcatattac
     4681 tcaggtaaag atggaaatga cagagcacag acatttattt tttaaattga tagggtagaa
     4741 aatgaaatgt acttctgttt attcttaata ctatatatat atatacacac atagttttag
     4801 caaattggaa ataatatatt catttgtatg gcaagataaa tgcagtcatc ttaatactag
     4861 tctatacatt tttgccaaat ggcgcaaata tacctccatt tatattttgt atcttaaaat
     4921 gtagtttaaa aataggacca tgtatgagac acttttttac aaaaagtgcc gtatatacat
     4981 atgtaacagg tgagtgtgtg tttaacataa tttataatta tttctgtcag tacagcgtat
     5041 atggaaaatt caagttgttt ttaacatatt caagtatgtt cagtataaaa taagttaatc
     5101 ccatttcata atgtaaatca tatttttgtt atttgccata ttttatttga agtgataaaa
     5161 ttttataact caaatttgaa tgtcatagta cattgtgtgc taaccatggc aagcaaacat
     5221 ttacatttgt tttttacaat aaatttcttt taaaatatac tttctatttt tctgtactga
     5281 catatgcaat aaattggtac attaaaaatt tga
//
