LOCUS       XM_024449677            2767 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ATP binding cassette subfamily D member 4
            (ABCD4), transcript variant X7, mRNA.
ACCESSION   XM_024449677
VERSION     XM_024449677.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000014.9) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_024449677.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2767
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
     gene            1..2767
                     /gene="ABCD4"
                     /gene_synonym="ABC41; EST352188; MAHCJ; P70R; P79R; PMP69;
                     PXMP1L"
                     /note="ATP binding cassette subfamily D member 4; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 43 ESTs, 470 long SRA reads, 1 Protein, and 98%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 33 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:5826"
                     /db_xref="HGNC:HGNC:68"
                     /db_xref="MIM:603214"
     CDS             232..1575
                     /gene="ABCD4"
                     /gene_synonym="ABC41; EST352188; MAHCJ; P70R; P79R; PMP69;
                     PXMP1L"
                     /codon_start=1
                     /product="lysosomal cobalamin transporter ABCD4 isoform
                     X7"
                     /protein_id="XP_024305445.1"
                     /db_xref="GeneID:5826"
                     /db_xref="HGNC:HGNC:68"
                     /db_xref="MIM:603214"
                     /translation="MASKLIISPFTLVYYTYQCFQSTGWLGPVSIFGYFILGTVVNKT
                     LMGPIVMKLVHQEKLEGDFRFKHMQIRVNAEPAAFYRAGHVEHMRTDRRLQRLLQTQR
                     ELMSKELWLYIGINTFDYLGSILSYVVIAIPIFSGVYGDLSPAELSTLVSKNAFVCIY
                     LISCFTQLIDLSTTLSDVAGYTHRIGQLRETLLDMSLKSQDCEILGESEWGLDTPPGW
                     PAAEPADTAFLLERVSISAPSSDKPLIKDLSLKISEGQSLLITGNTGTGKTSLLRVLG
                     GLWTSTRGSVQMLTDFGPHGVLFLPQKPFFTDGTLREQVIYPLKEVYPDSGSADDERI
                     LRFLELAGLSNLVARTEGLDQQVDWNWYDVLSPGEMQRLSFARLFYLQPKYAVLDEAT
                     SALTEEVESELYRIGQQLGMTFISVGHRQSLEKFHSLVLKLCGGGRWELMRIKVE"
ORIGIN      
        1 agagtccctc gggtctcagg tcatggcggt cgcggggccc gcgcccggag ctggcgccag
       61 gcccaggtta gatctgcaat ttctccagcg gttcctgcag atactgaagg ttttgtttcc
      121 ttcttggtca tcacaaaatg ccttgatgtt cctgaccctt ttgtgcctga ccctactggg
      181 gaccagcgca tcagccagga cgtggagcga ttctgccggc agctcagcag catggccagc
      241 aagctcatca tctccccgtt caccctcgtc tactacactt accagtgctt ccaaagcaca
      301 ggctggctcg ggcctgtgag catcttcggg tatttcatcc tggggaccgt ggtgaacaaa
      361 actttgatgg gccccattgt gatgaagctg gtgcatcagg agaagctgga gggagatttt
      421 aggttcaagc acatgcagat tcgggtgaat gcggagcctg ctgctttcta cagagctggg
      481 catgtggagc acatgaggac agaccgcagg ctgcagagac tccttcagac ccagagggag
      541 ctgatgtcca aggagctctg gctgtacatc ggcatcaaca cctttgacta tctgggcagc
      601 atcctgagtt acgttgtcat cgcaatcccc attttcagcg gggtctatgg agacctgagt
      661 cccgcagagc ttagcaccct ggtcagcaag aatgcctttg tgtgcatcta cctcatcagc
      721 tgcttcaccc agctcatcga cctgtccacg acgctctcag atgtggctgg ctacacgcac
      781 agaattgggc agcttcggga gacgcttctg gacatgtccc tgaagtcaca ggactgcgag
      841 atcctgggcg agagcgagtg gggcttggac acacccccag ggtggccagc ggcagagcca
      901 gcagacacag catttctcct tgagcgggtc tccatctctg ccccctcctc tgacaaaccc
      961 ctaatcaagg atctgagcct aaagatctcc gagggacaga gcctgctcat cacaggcaac
     1021 acgggcactg gcaagacctc cttgctccgg gttctgggtg gcctctggac gagtacacgg
     1081 ggctcagtgc agatgctgac ggactttggg ccccatgggg tgctattcct gccacaaaag
     1141 ccattcttca ctgacgggac ccttcgggag caggtgatat atcccctgaa ggaggtctac
     1201 cccgactcag gttctgccga tgatgagagg atcttgaggt tcttggaatt ggcaggcctg
     1261 tccaacttgg tggcaaggac agagggcctg gaccagcagg tggactggaa ctggtatgat
     1321 gttctgtccc cgggggagat gcaacggctc tcctttgccc gactcttcta cctgcagccg
     1381 aagtacgcag tgcttgatga agccaccagt gccctgacag aggaagtgga gagcgagctc
     1441 tatcgcatcg gccagcagct ggggatgacg ttcatcagtg tgggacatcg gcagagcctt
     1501 gagaagtttc attccttggt tctgaaactc tgtggaggag gaagatggga gctgatgaga
     1561 atcaaagtgg aatgaagctc tggcttttgg aaggagagcc acactgtggc gggtcggcgg
     1621 ccctcaggag agaccaggag gactgacagc gaagatcgag ctcaggttcg ccacatagat
     1681 cccgtgcagg agccacatgg gtcctgtgca ggacccctag cagtggtggg ctgagcccag
     1741 gtctaggttt ctgtggggga cactgaatct cccagtgttc agtctcccag gactctgctg
     1801 cctcagccag agcctccata tgcttgaagt gctgattacc tacaaatgat ttcagatcat
     1861 gtttgctaaa gagaaatctg gaagtgtgag atctgtaaga aatgaaagaa atgactcttg
     1921 gagtcaagag atctggaaat cttttaatca gttaaattgt gcagcaatag atttttaact
     1981 ttaactgacc atttaagttt tttaataagt tttttacaaa gaaaagttaa acattaaaaa
     2041 gaattacagc tttctgtctt ctctatcatg gaatgatctt ttttattgaa tctccagatt
     2101 tgtatttgac agcttggtgg gaagggaagc acactctgct gttctggaat cttatgccca
     2161 gggtttttca cttctcccca catctccctt tccacttgcc agtgttgtgt agttagaacc
     2221 tgaaccacta acttccaggg gcctttggtc tgccctacct taacccaaat gaaagtaaat
     2281 ccctttcccc ttagccaaaa taaggttggg ttttctaaaa aaatagtcta tattagggaa
     2341 caacaacagc aaattagaca aaacccagaa agcacaaagc atgaggtgga gttactgtgc
     2401 ccaaagtcct cactcagacc agtgcccctc cagttcagtt gtctatgtat taccttcctt
     2461 accttcataa tttttgccag gcttctgtac ttctagtact tgagttactt aatattttta
     2521 aaaacaaacc ttttaagttt aaatggattt ttaagtgaaa ttttacactt aacatagatg
     2581 gaaagtaact aaaaataaat acaagaaaaa ccatcggtgt tattaactta cggctagatg
     2641 ctgttgcctg catagactct gggcctgagg cttgttcatt ttgtaaaaaa gagaggtgag
     2701 gagttagacg gactggcact caactgagat ttttctcctt aataaaatca gaaagatgga
     2761 gtgagaa
//
