LOCUS       XM_005267942            2783 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ATP binding cassette subfamily D member 4
            (ABCD4), transcript variant X5, mRNA.
ACCESSION   XM_005267942
VERSION     XM_005267942.5
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000014.9) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_005267942.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2783
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
     gene            1..2783
                     /gene="ABCD4"
                     /gene_synonym="ABC41; EST352188; MAHCJ; P70R; P79R; PMP69;
                     PXMP1L"
                     /note="ATP binding cassette subfamily D member 4; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 40 ESTs, 450 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 59 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:5826"
                     /db_xref="HGNC:HGNC:68"
                     /db_xref="MIM:603214"
     CDS             185..1591
                     /gene="ABCD4"
                     /gene_synonym="ABC41; EST352188; MAHCJ; P70R; P79R; PMP69;
                     PXMP1L"
                     /codon_start=1
                     /product="lysosomal cobalamin transporter ABCD4 isoform
                     X5"
                     /protein_id="XP_005267999.1"
                     /db_xref="GeneID:5826"
                     /db_xref="HGNC:HGNC:68"
                     /db_xref="MIM:603214"
                     /translation="MTSITRTSASARTWSDSAGSSAAWPASSSSPRSPSSTTLTSASK
                     GWLGPVSIFGYFILGTVVNKTLMGPIVMKLVHQEKLEGDFRFKHMQIRVNAEPAAFYR
                     AGHVEHMRTDRRLQRLLQTQRELMSKELWLYIGINTFDYLGSILSYVVIAIPIFSGVY
                     GDLSPAELSTLVSKNAFVCIYLISCFTQLIDLSTTLSDVAGYTHRIGQLRETLLDMSL
                     KSQDCEILGESEWGLDTPPGWPAAEPADTAFLLERVSISAPSSDKPLIKDLSLKISEG
                     QSLLITGNTGTGKTSLLRVLGGLWTSTRGSVQMLTDFGPHGVLFLPQKPFFTDGTLRE
                     QVIYPLKEVYPDSGSADDERILRFLELAGLSNLVARTEGLDQQVDWNWYDVLSPGEMQ
                     RLSFARLFYLQPKYAVLDEATSALTEEVESELYRIGQQLGMTFISVGHRQSLEKFHSL
                     VLKLCGGGRWELMRIKVE"
ORIGIN      
        1 agagtccctc gggtctcagg tcatggcggt cgcggggccc gcgcccggag ctggcgccag
       61 ctgaagagct ttgatcagtt cacctgcaac ctgctgtatg tgagctggag gaaggacctc
      121 actgagcacc ttcaccgcct ctacttccgg ggccgtgcgt actacaccct caacgtgctg
      181 cgggatgaca tcgataaccc ggaccagcgc atcagccagg acgtggagcg attctgccgg
      241 cagctcagca gcatggccag caagctcatc atctccccgt tcaccctcgt ctactacact
      301 taccagtgct tccaaaggct ggctcgggcc tgtgagcatc ttcgggtatt tcatcctggg
      361 gaccgtggtg aacaaaactt tgatgggccc cattgtgatg aagctggtgc atcaggagaa
      421 gctggaggga gattttaggt tcaagcacat gcagattcgg gtgaatgcgg agcctgctgc
      481 tttctacaga gctgggcatg tggagcacat gaggacagac cgcaggctgc agagactcct
      541 tcagacccag agggagctga tgtccaagga gctctggctg tacatcggca tcaacacctt
      601 tgactatctg ggcagcatcc tgagttacgt tgtcatcgca atccccattt tcagcggggt
      661 ctatggagac ctgagtcccg cagagcttag caccctggtc agcaagaatg cctttgtgtg
      721 catctacctc atcagctgct tcacccagct catcgacctg tccacgacgc tctcagatgt
      781 ggctggctac acgcacagaa ttgggcagct tcgggagacg cttctggaca tgtccctgaa
      841 gtcacaggac tgcgagatcc tgggcgagag cgagtggggc ttggacacac ccccagggtg
      901 gccagcggca gagccagcag acacagcatt tctccttgag cgggtctcca tctctgcccc
      961 ctcctctgac aaacccctaa tcaaggatct gagcctaaag atctccgagg gacagagcct
     1021 gctcatcaca ggcaacacgg gcactggcaa gacctccttg ctccgggttc tgggtggcct
     1081 ctggacgagt acacggggct cagtgcagat gctgacggac tttgggcccc atggggtgct
     1141 attcctgcca caaaagccat tcttcactga cgggaccctt cgggagcagg tgatatatcc
     1201 cctgaaggag gtctaccccg actcaggttc tgccgatgat gagaggatct tgaggttctt
     1261 ggaattggca ggcctgtcca acttggtggc aaggacagag ggcctggacc agcaggtgga
     1321 ctggaactgg tatgatgttc tgtccccggg ggagatgcaa cggctctcct ttgcccgact
     1381 cttctacctg cagccgaagt acgcagtgct tgatgaagcc accagtgccc tgacagagga
     1441 agtggagagc gagctctatc gcatcggcca gcagctgggg atgacgttca tcagtgtggg
     1501 acatcggcag agccttgaga agtttcattc cttggttctg aaactctgtg gaggaggaag
     1561 atgggagctg atgagaatca aagtggaatg aagctctggc ttttggaagg agagccacac
     1621 tgtggcgggt cggcggccct caggagagac caggaggact gacagcgaag atcgagctca
     1681 ggttcgccac atagatcccg tgcaggagcc acatgggtcc tgtgcaggac ccctagcagt
     1741 ggtgggctga gcccaggtct aggtttctgt gggggacact gaatctccca gtgttcagtc
     1801 tcccaggact ctgctgcctc agccagagcc tccatatgct tgaagtgctg attacctaca
     1861 aatgatttca gatcatgttt gctaaagaga aatctggaag tgtgagatct gtaagaaatg
     1921 aaagaaatga ctcttggagt caagagatct ggaaatcttt taatcagtta aattgtgcag
     1981 caatagattt ttaactttaa ctgaccattt aagtttttta ataagttttt tacaaagaaa
     2041 agttaaacat taaaaagaat tacagctttc tgtcttctct atcatggaat gatctttttt
     2101 attgaatctc cagatttgta tttgacagct tggtgggaag ggaagcacac tctgctgttc
     2161 tggaatctta tgcccagggt ttttcacttc tccccacatc tccctttcca cttgccagtg
     2221 ttgtgtagtt agaacctgaa ccactaactt ccaggggcct ttggtctgcc ctaccttaac
     2281 ccaaatgaaa gtaaatccct ttccccttag ccaaaataag gttgggtttt ctaaaaaaat
     2341 agtctatatt agggaacaac aacagcaaat tagacaaaac ccagaaagca caaagcatga
     2401 ggtggagtta ctgtgcccaa agtcctcact cagaccagtg cccctccagt tcagttgtct
     2461 atgtattacc ttccttacct tcataatttt tgccaggctt ctgtacttct agtacttgag
     2521 ttacttaata tttttaaaaa caaacctttt aagtttaaat ggatttttaa gtgaaatttt
     2581 acacttaaca tagatggaaa gtaactaaaa ataaatacaa gaaaaaccat cggtgttatt
     2641 aacttacggc tagatgctgt tgcctgcata gactctgggc ctgaggcttg ttcattttgt
     2701 aaaaaagaga ggtgaggagt tagacggact ggcactcaac tgagattttt ctccttaata
     2761 aaatcagaaa gatggagtga gaa
//
