LOCUS       XM_017018993            8686 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ATP binding cassette subfamily D member 2
            (ABCD2), transcript variant X2, mRNA.
ACCESSION   XM_017018993
VERSION     XM_017018993.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000012.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017018993.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8686
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
     gene            1..8686
                     /gene="ABCD2"
                     /gene_synonym="ABC39; ALDL1; ALDR; ALDRP; hALDR"
                     /note="ATP binding cassette subfamily D member 2; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 7 ESTs, 36 long SRA reads, 1 Protein, and 92% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 5 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:225"
                     /db_xref="HGNC:HGNC:66"
                     /db_xref="MIM:601081"
     CDS             189..1859
                     /gene="ABCD2"
                     /gene_synonym="ABC39; ALDL1; ALDR; ALDRP; hALDR"
                     /codon_start=1
                     /product="ATP-binding cassette sub-family D member 2
                     isoform X2"
                     /protein_id="XP_016874482.1"
                     /db_xref="GeneID:225"
                     /db_xref="HGNC:HGNC:66"
                     /db_xref="MIM:601081"
                     /translation="MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRL
                     KQSGHGKKKAAAYPAAENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTT
                     ETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFV
                     NSAIRYLECKLALAFRTRLVDHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFS
                     QSVAHLYSNLTKPILDVMLTSYTLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSP
                     KFGKLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKSYKALADQMNLIL
                     SKRLWYIMIEQFLMKYVWSSSGLIMVAIPIITATGFADGEDGQKQVMVSERTEAFTTA
                     RNLLASGADAIERIMSSYKEVTELAGYTARVYNMFWVFDEVKRGIYKRTAVIQESESH
                     SKNGAKVELPLSDTLAIKGKVIDVDHGIICENVPIITPAGEVVASRLNFKVEEGMHLL
                     ITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQHMFYIPQSLSVFPSP"
ORIGIN      
        1 agatgcagcg gagtctgagc tctgctgcat ctgtcacagc agaacaaaat taaaaacaca
       61 acagtggaag agaaacgctg cagactatgg gacgctgtag gactttctaa aacatttgct
      121 ggggatttct gtgaagcatg atcttttaaa acgaattctt ttggaagccg gtttgggtaa
      181 ctgggaaaat gacacatatg ctaaatgcag cagctgatcg agtgaaatgg accagatcga
      241 gtgctgctaa gagggctgcc tgcctggtgg ctgcggcata tgctctgaaa accctctatc
      301 ccatcattgg caagcgttta aagcaatctg gccacgggaa gaaaaaagca gcagcttacc
      361 ctgctgcaga gaacacagaa atactgcatt gcaccgagac catttgtgaa aaaccttcgc
      421 ctggagtgaa tgcagatttc ttcaaacagc tactagaact tcggaaaatt ttgtttccaa
      481 aacttgtgac cactgaaaca gggtggctct gcctgcactc agtggctcta atctcaagaa
      541 cctttctttc tatctatgtg gctggtctgg atggaaaaat cgtgaaaagc attgtggaaa
      601 agaagcctcg gactttcatc atcaaattaa tcaagtggct tatgattgcc atccctgcta
      661 ccttcgtcaa cagtgcaata aggtacctgg aatgcaaatt ggctttggcc ttcagaactc
      721 gcctagtaga ccacgcctat gaaacctatt ttacaaatca gacttattat aaagtgatca
      781 atatggatgg gaggctggca aaccctgacc aatctcttac ggaggatatt atgatgttct
      841 cccaatctgt ggctcacttg tattccaatc tgaccaaacc tattttagat gtaatgctga
      901 cctcctatac actcattcaa actgctacat ccagaggagc aagcccaatt gggcccaccc
      961 tactagcagg acttgtggtg tatgccactg ctaaagtgtt aaaagcctgt tctcccaaat
     1021 ttggcaaact ggtggcagag gaagcacata gaaaaggcta tttgcggtat gtgcactcga
     1081 gaattatagc caatgtagaa gaaattgcct tttacagagg acataaggta gaaatgaaac
     1141 aacttcagaa aagttacaaa gctttagcag atcagatgaa cctcatttta tccaaacgtt
     1201 tgtggtacat catgatagaa cagttcctga tgaagtatgt ttggagcagc agtggactaa
     1261 ttatggtggc tatacctatt atcactgcaa ctggctttgc agatggtgag gatggccaaa
     1321 agcaagttat ggttagtgaa cggacagaag cctttaccac tgctcgaaat ttactggcct
     1381 ctggagctga tgctattgaa aggattatgt cttcatacaa agaggtcact gaattagcag
     1441 gctacactgc tcgagtgtac aatatgtttt gggtctttga tgaagtaaaa agaggcattt
     1501 ataagagaac tgctgtcatt caagaatctg aaagccatag caagaatgga gctaaggtag
     1561 aattacctct cagtgacaca ttggcaatta aaggaaaagt tattgatgtg gatcacggaa
     1621 ttatttgtga aaatgttccc ataattacac cagcaggaga agtggtggct tccaggctaa
     1681 acttcaaagt agaagaagga atgcatcttt tgataactgg tcccaatggt tgtgggaaaa
     1741 gttctctctt cagaattcta agtgggctct ggcctgtgta tgaaggagtc ctctataaac
     1801 cacctcctca acatatgttt tatattccac aaagtttatc tgtctttcca agtccctaag
     1861 gagagatttg tgatcccctg ctctcacttt cacaaatcca ctaatttatg gcctatttgt
     1921 tacttcctaa tcccctggta agtttctgtc ttcatccatg aaagccccta aacccaccct
     1981 tttacttgtt tattttgttc acctgctaac aaaattttat agtatgctaa caatcatcaa
     2041 aataataaat tggaatattt agtgggagtt gggggtagag agagagtggg agagaagcaa
     2101 cagaggaagg gacagaagga agaaagacag atgataatag atatttgctg acaaaatata
     2161 ttttgctcag agtaaaatct tgctttcttt tgtactagtt tttaaaaata atactccaga
     2221 agatcatttg catacatcac attacagttg ggcctctgta tctgcagctt ccacaacctt
     2281 ggattcaacc caccatgaat aaaaaatatt tttaaaataa acactgaaaa caacaacata
     2341 accataaaaa atcatacaaa caaaaaacca atgcatagta tttgtattgt gttaggtatt
     2401 acaagtaatc taaagatgat ttaaagtata tagggggatg tgtgttggtg atatgcaaat
     2461 actgtggcca ttttatataa aggcatctgt ggattttggt gttttctggg gtcctggaac
     2521 cagttccacc ctgggcacca acccatcatg taattctaac acgtatgctc ttactaccta
     2581 cgcttccttg gcagaaatat cttgaaaaag aaattttaat cgtaattttc ttactattca
     2641 aacttactat gcaggcccaa atactaaggc ccacaagatc tgaaatagat tcaggcttcc
     2701 cacaatggtg tacaaaaagg taacttgtat aaacttctgc ccacccatga ctttggagtc
     2761 tgagaaacaa aaggttcaga aagtgaaaga aggattatat ataagtatag aattaaatct
     2821 gatcaaatac tttttttaaa gaaagaaaaa gaaaaaaagg gagaaatagc tggagtattg
     2881 tgtttcatgt cagagagata acaatttttt tttcatttag tctttttagg atagacaata
     2941 attagcatat aatcttatga tgtttatgta tcatttagtt ataaataaaa acattcaact
     3001 aatggaaata aaaaccagaa ataagtgcct caagaaaggc aagaaatgct atggatgttc
     3061 aaaatgagga aaaaatagaa cagtgtgtca tttgacctga gttttgaaag taattcagga
     3121 tttgaacagt tgccatggat tgcatcagtt tctccaattt ctaaataggt aagaaatacc
     3181 acagattcaa gtaagcagaa gtttttgttt tttggacact tctggatagc ataatgttct
     3241 ttcctactct cctctaacac acgatgctga gaaaagaaag catttcttag actcatcccc
     3301 actaataaga agtcatcagt acatactgga aatgatagtg ctcatcctct cagtccttac
     3361 tcgtttgctg cactgtttct tttagctgaa gttctttgat ttaatttttt aaggtttttt
     3421 agtaatttgg atgtttgcca ttttcccagt ctctagctaa ggagctcaac ctgctctcta
     3481 taagtaagtg acacaatttt atgtgctaaa ttacttctca aaaagcataa taaaagatga
     3541 cggtagcttg cttccacaac actcattatt ttttgtttcc tgttttcaga agatattctg
     3601 aaattatgag taacatttta cttatcagct caatatttgt ttatttctaa ctagtaacta
     3661 ctacttcatt cacagggttg tgtgcacaag taccatgtta cttaatctcc tagattaaat
     3721 ataaatacta cttgataaat aaagttatga atcacatttt aaaattaaat gcaacataaa
     3781 agtcttaaat ttgattgtaa gcaggaatgg taaacatcac taattagatt gtacaggaaa
     3841 ttaaatatag ataataactt tatttctatc ttgttatgca tgaataatac atattaatta
     3901 tgttctgtat aagttatgct aaatagagta tttttaagta attaaattga atttcaaagg
     3961 gactacatac tttacttagc gttatatgga atttcaaagc cagagttaga ctataccaag
     4021 tctttgaata caaatcttct gtactcactg cctctcattt tcagattaat aagattatca
     4081 catttaagca tcttaagatg aaaaaaatcc tactgttttt gatcttaaat attttctcag
     4141 ataatcataa cacagtctgt attactttcc caactttctg aggaataaca aaatatcatt
     4201 ctttataatt tgtcttcact tttcaaaaat atctgtatct tcagctatct tcttttttct
     4261 ttttcttttt ttgaaacaga gtgtcactct gtcacccagg ctggagtgca gtggcacaat
     4321 cttggctcac tgcagcctct gcctcctggg ttcaccatgg taccaccatg cacggctaat
     4381 tttttattat ttgtattgac agggttttcc taccttgcca gggctaatct tgaactcctg
     4441 gcctcaagtg attatcgcac ctcagcttcc caagtaactg ggattacagg cgcccaccac
     4501 gaaacccaga gaatttttgt atttttagta gagttggggt ttcatcacgt tggccaggcc
     4561 ggtctcgaac tcctggcctc aagtgatcca cccgccttgg cctcccaaag tgctgggatt
     4621 aaacacgtga gccactctac ctggccattg tattcttcaa ctgtttttct aaggaagaag
     4681 agcttaagac atgaaatctc agcctttaca agtactagta tatttatgtt ttctttggta
     4741 tctttaattg atatctatat tttctttgat ggcatttcca cttcttcctt ttaatgatat
     4801 agtgtgtgtg ttttaaaaaa ttatatgcat taaaattgat tttatcctga gaatgttgtg
     4861 acctcttgag ataactgttg ggtcctaggc atcctgaacc aggattgagc atctctaggg
     4921 tattgttatt ttttgtaatt aacaatatgt caaacaatta gtgtgtgcta gtcacaattc
     4981 tacatatata agtttcttat ttttctgtat gacaacctat aaagttggta ttagtatccc
     5041 tattttgtga gaaaacttaa agaggtttaa gtcctccagt ggataaatgc tggagctaga
     5101 atttgaactc agatgtgcct taccctaaag tcattttgcc ttattggtat caacaggggc
     5161 atgtgtatga aaaattacta ccctttatcc tgaccttgca agtatcacca gctaaggttg
     5221 ttttcttggt gtgctgatct gtactaatat caagctgtgg tttggaggca gaggtcctca
     5281 taatcctcga tgtacatggc aattaagtca attttaacat acattttagc ataggtactt
     5341 ggccatcatt cagatatgtt aaggtgaagg aagctatatt ctcatatgaa agtgaaattt
     5401 taaaaaattt attggtgttc aattcatttt caaattaaat tttattctct actctttcct
     5461 attcttctaa aattcatttc tccataaaat tttaaagaat ttttcaaaaa tagtccctta
     5521 attttaaatc agaattcttg ttgagatata aaacaagcaa accttaattt tcaggatgca
     5581 ttatggctta aaaagatcat gacttaccct ttatgtcatc aaaagaagag attgtcgctt
     5641 gcaacagtga agacggtgtt ttatttcaga agttctgcag aaagggcttg aaggacgata
     5701 ataccaacat tggcacaact gccctgtgca ctaagaagta cttgcaccaa ataagcttta
     5761 tggatatttt aaaatatgaa gttctgggct gggcctggtg gctcatgact gtaatcccag
     5821 cactttagga ggctgaggtt ggataatcac ttgaggccag gaatttaagg ttagccctgg
     5881 caacataggg ggaccccgtc aatacaaata ataaaaaagt agctggatat ggtggtactt
     5941 gcctgtagtc ccagctactt aagaggctga ggtgggaggg ctgcttgagt ctgggaagtt
     6001 gaggctgcag tgagccatga ttgcaccact gcactctggc ctgggcaaca gagtgagatg
     6061 ctatctcaaa agaataaaaa taaaaataaa acaaaaaaat aaaagctgtg aagttccatt
     6121 ttctattgtt tctatatgaa tgacttccaa atctaagatt tcttctttgt agggatcagg
     6181 gaactctgtg ttatatatca acattgttta acccacacat ataaaaccag atgatggcta
     6241 ttaactagaa agcatatgag atcaggtcag aagaactgat ttgcctcttt tctctatgga
     6301 ggacagaaag ggtgctgtta aagtattctc agtgagatcc ttgctttttt tctttttatc
     6361 caagatctca gattttaaaa atgaggatgt ggtctggaaa aggatctaag caagaatctg
     6421 gggtatgctg ttttaaatat cttaatctca attttcctat aggtctctag cttttggacc
     6481 tgtcaattct taatgaatat ctagctgcca aaaggcaaac agggtgcacc tcttgaggac
     6541 aaggagtgtg tttatttaag aaagaggcag actagcaggc cactgcctga gtggaatatg
     6601 ggtctataaa agccactgga ataaaggagg aatgtgatgt ggcttaatcc agagctcctc
     6661 acagaactct atacctatgt actgtgccaa tgtgtatgta ggttacatat ctattgtcct
     6721 gctgccctca aagcaaagaa atatggcttt gggagtaggg gttgtactgg aacagacttt
     6781 gcccttgttg agtcactgtt gaacaaactt ttatagatta aaagctagaa aaggcaacca
     6841 catgtctctg tacagcactg gtaggatcct agtaaatata ttgtaattgt gcaataaata
     6901 tctgataagt gattgactga atgaatgaac atctccacag atttggtttc tactgccaag
     6961 tcaatctggt accttacact aattatgagc aatctattta ttttgctgct tgcagtaggt
     7021 atgttgcaaa attctcttta tgatggggat aaatatctgt catttaacat gtcctttttt
     7081 agaaaattat tttaaccaca aggaaggctt agtagcattg ctgtagcaaa ttgacttcta
     7141 ttccttgctt tctgactgtt agacttacag ccaagtaatc tttgtataaa tacctttggg
     7201 cagtcagttg acagaaatag aagttgtaca ttttagttcc tcctgtgtag tagttggtac
     7261 agttcagttt ttttaaatct cttttaaaga gatctataaa tgtaaacaca attttctata
     7321 gctttctatg gcttggaaga atgctaaaga tactttttaa aatctttaac ttttctaagg
     7381 gctcatttat aaaagtaata atgaaaaaac tcccctctca ctcaaaagtt tttctcattt
     7441 tatgagtact attacattaa accatatgga actgcaattt ttataggtca aatatcagca
     7501 atttaaatgg taatctgata taatgataaa tactcttaaa gttgactttt acagaaattt
     7561 gcatttttaa cagcttagca atactttaat tcttccacta ataatatatt tatttattta
     7621 cttattgaga cagtgtctca ctctattgcc caggctggag ttcagtgaca caatcttggc
     7681 tcactgcaac ctctgtctcc agggttcaag agattcttgt gcctcagcct cccaagtagc
     7741 tgggattaca ggtgtgtgcc accacacctg gctaattttt gcatttttag tagagatggg
     7801 gtttcaccat gttgagcagg ctggtctcaa acttctgacc tcaggtgatt cacccagctt
     7861 ggcctcccaa attacgggga ttacagatgc gagccactgc acctggccta atattatttt
     7921 tattacttgg aaataaacct catccctgct cttaagaggc tattctcatc tctgttttgg
     7981 aatctagaaa tatcttatcc aaaagatata atttcagtaa tagtaaatat ctattttcac
     8041 ttgaatattt cttcttatta tcacacattt tttaagaata ctataaatga ctcaaatcta
     8101 gttctttcta tgcatgaaaa accctgatgc aatgattggt tccagcatgt atagttatgt
     8161 gaattattga tagttaaatt ttatgccttt cagattgtta acttcttttg ctacgacaac
     8221 acagcagtac ttagtggtac attattctta aacttaacac atctcatgcc ttaaatacag
     8281 ttaacattgc tgcaaaattt ttatcaatat tgttccaatt aaattttata tgattacttt
     8341 aaaaatttgt tttctctgca tataggcctt tcatgtcaca cttttttttc tcctctggat
     8401 ttgaattggt tttttgctct caatttagga aatatttaga attttgtgtc attcagaagc
     8461 tccaagcaca tagatacagc taacacttct cagtgctttc ccattctttc tagctttgtc
     8521 ttagagaata ataaaaaagt aactctaaca aacatcaata cattttacca aaaaaaaaaa
     8581 atcactgtca gattacttag atgttaatgc agaaaagtgg gaatataatg caaagtataa
     8641 aagcaccttg agacattagt aacaaaacta taaaaagcca taatca
//
