LOCUS       XM_047434149            6159 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ATP binding cassette subfamily C member 1
            (ABCC1 blood group) (ABCC1), transcript variant X19, mRNA.
ACCESSION   XM_047434149
VERSION     XM_047434149.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000016.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6159
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
     gene            1..6159
                     /gene="ABCC1"
                     /gene_synonym="ABC29; ABCC; DFNA77; GS-X; MRP; MRP1"
                     /note="ATP binding cassette subfamily C member 1 (ABCC1
                     blood group); Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 4 mRNAs, 35 ESTs, 646 long SRA
                     reads, 5 Proteins, and 99% coverage of the annotated
                     genomic feature by RNAseq alignments, including 7 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:4363"
                     /db_xref="HGNC:HGNC:51"
                     /db_xref="MIM:158343"
     CDS             137..4387
                     /gene="ABCC1"
                     /gene_synonym="ABC29; ABCC; DFNA77; GS-X; MRP; MRP1"
                     /codon_start=1
                     /product="multidrug resistance-associated protein 1
                     isoform X19"
                     /protein_id="XP_047290105.1"
                     /db_xref="GeneID:4363"
                     /db_xref="HGNC:HGNC:51"
                     /db_xref="MIM:158343"
                     /translation="MALRGFCSADGSDPLWDWNVTWNTSNPDFTKCFQNTVLVWVPCF
                     YLWACFPFYFLYLSRHDRGYIQMTPLNKTKTALGFLLWIVCWADLFYSFWERSRGIFL
                     APVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTA
                     LKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSR
                     ITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVV
                     YSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAI
                     HDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSG
                     MRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQ
                     VILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEI
                     LNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFA
                     VYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEE
                     LEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGC
                     GKSSLLSALLAEMDKVEGHVAIKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQEL
                     LARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQ
                     LSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIG
                     LFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIA
                     VFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMI
                     PEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLES
                     VSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRL
                     ECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAV
                     ERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTING
                     GEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDP
                     VLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQR
                     QLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMD
                     YTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMAKDAGLV"
ORIGIN      
        1 gccgccgccg ccgccgccag cgctagcgcc agcagccggg cccgatcacc cgccgcccgg
       61 tgcccgccgc cgcccgcgcc agcaaccggg cccgatcacc cgccgcccgg tgcccgccgc
      121 cgcccgcgcc accggcatgg cgctccgggg cttctgcagc gccgatggct ccgacccgct
      181 ctgggactgg aatgtcacgt ggaataccag caaccccgac ttcaccaagt gctttcagaa
      241 cacggtcctc gtgtgggtgc cttgttttta cctctgggcc tgtttcccct tctacttcct
      301 ctatctctcc cgacatgacc gaggctacat tcagatgaca cctctcaaca aaaccaaaac
      361 tgccttggga tttttgctgt ggatcgtctg ctgggcagac ctcttctact ctttctggga
      421 aagaagtcgg ggcatattcc tggccccagt gtttctggtc agcccaactc tcttgggcat
      481 caccatgctg cttgctacct ttttaattca gctggagagg aggaagggag ttcagtcttc
      541 agggatcatg ctcactttct ggctggtagc cctagtgtgt gccctagcca tcctgagatc
      601 caaaattatg acagccttaa aagaggatgc ccaggtggac ctgtttcgtg acatcacttt
      661 ctacgtctac ttttccctct tactcattca gctcgtcttg tcctgtttct cagatcgctc
      721 acccctgttc tcggaaacca tccacgaccc taatccctgc ccagagtcca gcgcttcctt
      781 cctgtcgagg atcaccttct ggtggatcac agggttgatt gtccggggct accgccagcc
      841 cctggagggc agtgacctct ggtccttaaa caaggaggac acgtcggaac aagtcgtgcc
      901 tgttttggta aagaactgga agaaggaatg cgccaagact aggaagcagc cggtgaaggt
      961 tgtgtactcc tccaaggatc ctgcccagcc gaaagagagt tccaaggtgg atgcgaatga
     1021 ggaggtggag gctttgatcg tcaagtcccc acagaaggag tggaacccct ctctgtttaa
     1081 ggtgttatac aagacctttg ggccctactt cctcatgagc ttcttcttca aggccatcca
     1141 cgacctgatg atgttttccg ggccgcagat cttaaagttg ctcatcaagt tcgtgaatga
     1201 cacgaaggcc ccagactggc agggctactt ctacaccgtg ctgctgtttg tcactgcctg
     1261 cctgcagacc ctcgtgctgc accagtactt ccacatctgc ttcgtcagtg gcatgaggat
     1321 caagaccgct gtcattgggg ctgtctatcg gaaggccctg gtgatcacca attcagccag
     1381 aaaatcctcc acggtcgggg agattgtcaa cctcatgtct gtggacgctc agaggttcat
     1441 ggacttggcc acgtacatta acatgatctg gtcagccccc ctgcaagtca tccttgctct
     1501 ctacctcctg tggctgaatc tgggcccttc cgtcctggct ggagtggcgg tgatggtcct
     1561 catggtgccc gtcaatgctg tgatggcgat gaagaccaag acgtatcagg tggcccacat
     1621 gaagagcaaa gacaatcgga tcaagctgat gaacgaaatt ctcaatggga tcaaagtgct
     1681 aaagctttat gcctgggagc tggcattcaa ggacaaggtg ctggccatca ggcaggagga
     1741 gctgaaggtg ctgaagaagt ctgcctacct gtcagccgtg ggcaccttca cctgggtctg
     1801 cacgcccttt ctggtggcct tgtgcacatt tgccgtctac gtgaccattg acgagaacaa
     1861 catcctggat gcccagacag ccttcgtgtc tttggccttg ttcaacatcc tccggtttcc
     1921 cctgaacatt ctccccatgg tcatcagcag catcgtgcag gcgagtgtct ccctcaaacg
     1981 cctgaggatc tttctctccc atgaggagct ggaacctgac agcatcgagc gacggcctgt
     2041 caaagacggc gggggcacga acagcatcac cgtgaggaat gccacattca cctgggccag
     2101 gagcgaccct cccacactga atggcatcac cttctccatc cccgaaggtg ctttggtggc
     2161 cgtggtgggc caggtgggct gcggaaagtc gtccctgctc tcagccctct tggctgagat
     2221 ggacaaagtg gaggggcacg tggctatcaa gacgcggatc ttggtcacgc acagcatgag
     2281 ctacttgccg caggtggacg tcatcatcgt catgagtggc ggcaagatct ctgagatggg
     2341 ctcctaccag gagctgctgg ctcgagacgg cgccttcgct gagttcctgc gtacctatgc
     2401 cagcacagag caggagcagg atgcagagga gaacggggtc acgggcgtca gcggtccagg
     2461 gaaggaagca aagcaaatgg agaatggcat gctggtgacg gacagtgcag ggaagcaact
     2521 gcagagacag ctcagcagct cctcctccta tagtggggac atcagcaggc accacaacag
     2581 caccgcagaa ctgcagaaag ctgaggccaa gaaggaggag acctggaagc tgatggaggc
     2641 tgacaaggcg cagacagggc aggtcaagct ttccgtgtac tgggactaca tgaaggccat
     2701 cggactcttc atctccttcc tcagcatctt ccttttcatg tgtaaccatg tgtccgcgct
     2761 ggcttccaac tattggctca gcctctggac tgatgacccc atcgtcaacg ggactcagga
     2821 gcacacgaaa gtccggctga gcgtctatgg agccctgggc atttcacaag ggatcgccgt
     2881 gtttggctac tccatggccg tgtccatcgg ggggatcttg gcttcccgct gtctgcacgt
     2941 ggacctgctg cacagcatcc tgcggtcacc catgagcttc tttgagcgga cccccagtgg
     3001 gaacctggtg aaccgcttct ccaaggagct ggacacagtg gactccatga tcccggaggt
     3061 catcaagatg ttcatgggct ccctgttcaa cgtcattggt gcctgcatcg ttatcctgct
     3121 ggccacgccc atcgccgcca tcatcatccc gccccttggc ctcatctact tcttcgtcca
     3181 gaggttctac gtggcttcct cccggcagct gaagcgcctc gagtcggtca gccgctcccc
     3241 ggtctattcc catttcaacg agaccttgct gggggtcagc gtcattcgag ccttcgagga
     3301 gcaggagcgc ttcatccacc agagtgacct gaaggtggac gagaaccaga aggcctatta
     3361 ccccagcatc gtggccaaca ggtggctggc cgtgcggctg gagtgtgtgg gcaactgcat
     3421 cgttctgttt gctgccctgt ttgcggtgat ctccaggcac agcctcagtg ctggcttggt
     3481 gggcctctca gtgtcttact cattgcaggt caccacgtac ttgaactggc tggttcggat
     3541 gtcatctgaa atggaaacca acatcgtggc cgtggagagg ctcaaggagt attcagagac
     3601 tgagaaggag gcgccctggc aaatccagga gacagctccg cccagcagct ggccccaggt
     3661 gggccgagtg gaattccgga actactgcct gcgctaccga gaggacctgg acttcgttct
     3721 caggcacatc aatgtcacga tcaatggggg agaaaaggtc ggcatcgtgg ggcggacggg
     3781 agctgggaag tcgtccctga ccctgggctt atttcggatc aacgagtctg ccgaaggaga
     3841 gatcatcatc gatggcatca acatcgccaa gatcggcctg cacgacctcc gcttcaagat
     3901 caccatcatc ccccaggacc ctgttttgtt ttcgggttcc ctccgaatga acctggaccc
     3961 attcagccag tactcggatg aagaagtctg gacgtccctg gagctggccc acctgaagga
     4021 cttcgtgtca gcccttcctg acaagctaga ccatgaatgt gcagaaggcg gggagaacct
     4081 cagtgtcggg cagcgccagc ttgtgtgcct agcccgggcc ctgctgagga agacgaagat
     4141 ccttgtgttg gatgaggcca cggcagccgt ggacctggaa acggacgacc tcatccagtc
     4201 caccatccgg acacagttcg aggactgcac cgtcctcacc atcgcccacc ggctcaacac
     4261 catcatggac tacacaaggg tgatcgtctt ggacaaagga gaaatccagg agtacggcgc
     4321 cccatcggac ctcctgcagc agagaggtct tttctacagc atggccaaag acgccggctt
     4381 ggtgtgagcc ccagagctgg catatctggt cagaactgca gggcctatat gccagcgccc
     4441 agggaggagt cagtacccct ggtaaaccaa gcctcccaca ctgaaaccaa aacataaaaa
     4501 ccaaacccag acaaccaaaa catattcaaa gcagcagcca ccgccatccg gtcccctgcc
     4561 tggaactggc tgtgaagacc caggagagac agagatgcga accacccaaa acacgcacac
     4621 cctgcccctg gtgccctgag acagacacac agcctcacgc ccccaggaat gcaagtggtt
     4681 tcctggtgct tcccacggag gagttttggc agccagactt ctggaggaat tggttgtata
     4741 gaagatccta gtgaccaaat tcagcctact gcctcggatc tctccagccg aagtctgtgg
     4801 actgcaagtc tttgagatgc ttctggctcc catcacctct aacatccttg tctgggtcta
     4861 ccaggaacgc ttcatttcct tggggctgca gttttgtggt tgaggggcct ggagaaaatc
     4921 attttctccc cttggcagtg tcccagggcc ctggatggtc ctcttaccaa catctggtct
     4981 tccaggcact caaaagctgg gaaccagcat ctcagcgcca gctctaccag ttctcgtttt
     5041 gggccagagg cagcctctgc actcccacgc ctgtcctcct ggaagggacc tggttggact
     5101 aacggctaac ctggacctgg aactgtaggg ccaggggatt gtctcagggc cgacgttcca
     5161 cctggggctt ccctccccac ccaccccgac tccaggcttt cccttttttc ttttgttcaa
     5221 cattgtaaga acaatcaatg ctgttattac tgttcccacc atgattgatg tggggtaaat
     5281 attaaggaga tggcctcatg ggaatttgac cttgactaga aatagagact gagagtgagc
     5341 aaccagctgg aaggtactat gccagtccta gcagaaaaat gtgttagggg cctggcccaa
     5401 agcagtgttg gttgcttaca gtgttgattg attttgttct tttttcttac cacctctttt
     5461 ctttccctct catggtacct gctcatggtt atgaagcttt caaagtaaag aacacgaaat
     5521 acctcccaag tattaccagt gggtaccaaa aaaatgtccc cttgagtctt ttccttgttt
     5581 ttagatgtta attctctccc ttggcatccg gttagccccc cagggggggc agcattgtgg
     5641 agaacttgat atttagttac tgatgctctt ccaggacacg aaaagaaccc atctttgaat
     5701 atcaatgatt tttttttttt aagtactgtt ccggggagaa aaacagtctc aaaacttgaa
     5761 cttcttggga atagaagtgt tgggctgaga agtaacattc ccaggaaata gtgagaagct
     5821 cgccctgtgt ttgaaaccgt gttggtctct gtgttcctgg aagaaaacag ggaagcagca
     5881 tcttttaaag cctgttcttt aaggtgtctc gttagagccc aaagtggaat ccggaaggca
     5941 gccagagctg aggctgcccc aagactcaga cttgctaaga attacgccgc cgacttcaaa
     6001 cccagagagc atctttcttt taggcgaaaa cgcatatatt tattttttgt aagttatacc
     6061 attctttcac attagataaa ctaagttttg ggggatcctt ttgtaatgac ttacactgga
     6121 aatgcgaaca tttgcagtaa aaaaatatat atatatcta
//
